Journal of Cartilage & Joint Preservation最新文献

{"title":"From past and current cartilage surgical techniques to NextGen approaches","authors":"Ignacio Dallo , Cassandra A. Lee , Luis Eduardo Passarelli Tirico , Rachel M. Frank","doi":"10.1016/j.jcjp.2024.100188","DOIUrl":"10.1016/j.jcjp.2024.100188","url":null,"abstract":"","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"4 2","pages":"Article 100188"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254524000246/pdfft?md5=e6e5add58ae9a40dd9b94b4dcc44d09e&pid=1-s2.0-S2667254524000246-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140768526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cell-free biomimetic scaffold for chondral and osteochondral lesions: surgical technique for custom and standardized implantation","authors":"Luca Andriolo ,&nbsp;Luca De Marziani ,&nbsp;Alessandro Di Martino ,&nbsp;Angelo Boffa ,&nbsp;Stefano Zaffagnini ,&nbsp;Giuseppe Filardo","doi":"10.1016/j.jcjp.2024.100173","DOIUrl":"10.1016/j.jcjp.2024.100173","url":null,"abstract":"<div><h3>Introduction</h3><p>Cell-free chondral and osteochondral scaffolds have been introduced to address lesions of the articular surface. A proper implantation technique is key to favor scaffold integration, regenerative processes, and positive clinical outcomes.</p></div><div><h3>Objectives</h3><p>The purpose of this article is to describe indications and surgical steps for both the custom traditional free-hand implantation approach and an innovative minimally invasive technique for the standardized implantation of this biomimetic cell-free scaffold (MaioRegen; Fin-Ceramica Faenza Spa).</p></div><div><h3>Methods</h3><p>Indications and contraindications for this scaffold implantation have been provided. The required steps for surgical preparation, implantation technique, and postoperative management have been described as well to address articular surface lesions of the knee.</p></div><div><h3>Results</h3><p>A dedicated instrumentation for circular implants of different sizes has been developed to allow more precise preparation of the depth and width of the defect, reducing the invasiveness and increasing implant stability. The custom free-hand technique with chisels and osteotomes remains useful when the lesion does not allow the use of the standardized instrumented technique. In case further stability of the implant is needed, fibrin glue addition should be considered.</p></div><div><h3>Conclusions</h3><p>By guiding the readers with the key perioperative and intraoperative steps, chondral and osteochondral defects can be addressed with the use of a cell-free scaffold, maximizing implant stability.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"4 2","pages":"Article 100173"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266725452400009X/pdfft?md5=88c34609da3d3d4d0570d11da9082792&pid=1-s2.0-S266725452400009X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140277255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the potential of mesenchymal stem/stromal cell-derived extracellular vesicles as cell-free therapy for osteoarthritis: a narrative review","authors":"Kazunori Shimomura ,&nbsp;Keng Lin Wong ,&nbsp;Samundeeswari Saseendar ,&nbsp;Sathish Muthu ,&nbsp;Sebastian Concaro ,&nbsp;Tiago Lazzaretti Fernandes ,&nbsp;Ansar Mahmood","doi":"10.1016/j.jcjp.2024.100184","DOIUrl":"10.1016/j.jcjp.2024.100184","url":null,"abstract":"<div><h3>Introduction</h3><p>Mesenchymal stem/stromal cell (MSC)-based therapies in cartilage repair and osteoarthritis (OA) treatment have gained attention. Recently, there has been increasing evidence to suggest that MSCs secrete a wide range of trophic factors to modulate the injured tissue environment. Extracellular vesicles (EVs) have been suggested to explain the positive and sometimes curative effect, through the paracrine stimulation of the resident progenitor cells to aid in repair.</p></div><div><h3>Objectives</h3><p>To give a narrative review of the current evidence for MSC-derived EV’s potential therapeutic effects and future perspectives for the treatment of OA.</p></div><div><h3>Methods</h3><p>A literature search was conducted using the MEDLINE databases in November 2023. A total of 24 animal studies describing EV, including exosomes utilized in cartilage and OA treatments were identified and analyzed.</p></div><div><h3>Results</h3><p>Preclinical animal studies indicated that EVs could enhance the therapeutic effects for the treatment of OA, although the purification methods for EVs and their cell sources would be highly relevant to therapeutic efficacy. In contrast, there have been no published clinical studies regarding EVs for the treatment of OA, and thus, properly controlled clinical trials and regulations are essential steps in future clinical applications.</p></div><div><h3>Conclusions</h3><p>The current evidences suggest that the administration of MSC-derived EVs into damaged joints could effectively reduce cartilage loss and alleviate the progression of OA. In contrast, there are still several potential problems to be solved, including their classification, safety and toxicity in clinical use, as well as optimal dosage and frequency for human administration.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"4 2","pages":"Article 100184"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254524000209/pdfft?md5=7691bdef97dc2adbd01d0448c6558dae&pid=1-s2.0-S2667254524000209-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140791294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic review of techniques in cartilage imaging","authors":"Mary Elizabeth Buchanan ,&nbsp;Brian Keegan Markhardt","doi":"10.1016/j.jcjp.2023.100155","DOIUrl":"10.1016/j.jcjp.2023.100155","url":null,"abstract":"<div><h3>Introduction</h3><p>This narrative review provides a historical overview and updates on the current status of qualitative and quantitative magnetic resonance imaging (MRI) for the evaluation of articular cartilage. The review emphasizes the basic physics principles underlying common cartilage-specific imaging sequences, provides explanations of the magnetic resonance pulse sequences used in articular cartilage imaging, and highlights the advantages and limitations of different pulse sequences.</p></div><div><h3>Objectives</h3><p>To review current literature on qualitative and qualitative MRI for the evaluation of articular cartilage.</p></div><div><h3>Methods</h3><p>A computer-based search of the PubMed database was used to perform a comprehensive literature review on MRI for evaluation of articular cartilage. All journals were considered, and all relevant articles were retrieved. Relevant material was drawn from the years 1977 to 2023 and a total of 84 publications were ultimately included in the review.</p></div><div><h3>Results</h3><p>The literature review highlights the physics principles and rationale underlying the most commonly used cartilage-specific MRI sequences.</p></div><div><h3>Conclusions</h3><p>MRI is the optimal noninvasive method for the assessment of articular cartilage. Many factors affect the clinical utility of various cartilage-specific MRI sequences. It is important that radiologists and clinicians alike have a basic understanding of the optimal methods for cartilage imaging.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"4 1","pages":"Article 100155"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254523000616/pdfft?md5=54d24bd6a1f7538e2b0a32fd34b66741&pid=1-s2.0-S2667254523000616-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134016926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introduction to imaging of cartilage","authors":"Alexander N. Merkle,&nbsp;Corey K. Ho","doi":"10.1016/j.jcjp.2023.100164","DOIUrl":"10.1016/j.jcjp.2023.100164","url":null,"abstract":"","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"4 1","pages":"Article 100164"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254523000707/pdfft?md5=508359a47ed56ea4920a52544e4df039&pid=1-s2.0-S2667254523000707-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139192804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Normal variants, imaging artifacts, and other diagnostic pitfalls in articular cartilage imaging of the extremities","authors":"John H. Schilling,&nbsp;Paulo Miro,&nbsp;Brian Y. Chan","doi":"10.1016/j.jcjp.2023.100147","DOIUrl":"10.1016/j.jcjp.2023.100147","url":null,"abstract":"<div><h3>Introduction</h3><p>Imaging of the articular cartilage of the extremities is a complex topic that is continually refined through advancements in imaging, surgery, and conservative management of chondral pathology. However, there are many commonly encountered pitfalls in articular cartilage imaging, which are critical for both radiologists and surgeons to be aware of.</p></div><div><h3>Objectives</h3><p>This review will overview the basic concepts of imaging of the cartilage, with a focus on magnetic resonance imaging, including a discussion of magic angle, chemical shift, and susceptibility artifacts that can be mistaken for abnormal cartilage.</p></div><div><h3>Methods</h3><p>A review of described variant cartilage anatomy and imaging artifacts from the imaging and arthroscopic literature is undertaken with illustrative examples retrieved from the University of Utah picture archiving and communication system (PACS).</p></div><div><h3>Results</h3><p>Tools for distinguishing pathologic cartilage from the expected appearance of normal variant accessory ossicles, coalitions, partitions, and the normal labrum are introduced. Joint-specific considerations of commonly encountered cartilage-related entities in the shoulder, elbow, wrist, hip, knee, ankle, and foot are also reviewed.</p></div><div><h3>Conclusions</h3><p>Correlation of imaging, arthroscopic, and clinical findings is key to reducing diagnostic dilemmas, preventing inadvertent overestimation of disease, and ensuring appropriate intervention.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"4 1","pages":"Article 100147"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254523000537/pdfft?md5=0368bb127ea200d0c2c9f556d2210402&pid=1-s2.0-S2667254523000537-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128079614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone marrow signal abnormalities in arthritis and trauma","authors":"David C. Gimarc ,&nbsp;Mary K. Jesse Lowry","doi":"10.1016/j.jcjp.2023.100157","DOIUrl":"10.1016/j.jcjp.2023.100157","url":null,"abstract":"<div><p>Joint pain and dysfunction are common presenting symptoms of both younger and older patients, resulting in significant cost and burden to the healthcare system. In both the acute and chronic setting, the advanced imaging evaluation for assessing joint dysfunction most commonly utilizes magnetic resonance imaging that allows for detailed evaluation of all components of a joint, including the cartilage, bone, fibrocartilage, and ligamentous components. Signal alterations of the subchondral bone and marrow have been recently recognized as an important component in both trauma and arthritis and modern treatment strategies focus on addressing both the cartilage and bone in an attempt to optimize joint preservation and restore function. The presence of bone marrow signal abnormalities is often associated with patient symptoms, cartilage loss, and risk of disease progression. A thorough understanding of the unique anatomy and biomechanics of the chondro-osseous junction can help to explain the many marrow signal abnormalities and clinical implications that are commonly encountered by imagers. In this review article, we will describe the anatomy and basic physiology of the subchondral bone, and discuss multiple pathologic appearances of the bone with an emphasis on edema-like signal changes seen in the setting of osteoarthritis and trauma.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"4 1","pages":"Article 100157"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266725452300063X/pdfft?md5=c1ca8eb91204583e25bc6120f9d47179&pid=1-s2.0-S266725452300063X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136128438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic resonance imaging-arthroscopy correlation for chondral pathology in commonly imaged joints: a narrative review","authors":"Ian Savage-Elliott ,&nbsp;Andrew J. Hughes ,&nbsp;Jairo Triana ,&nbsp;Zachary I. Li ,&nbsp;Michael J. Alaia ,&nbsp;Erin F. Alaia","doi":"10.1016/j.jcjp.2023.100154","DOIUrl":"10.1016/j.jcjp.2023.100154","url":null,"abstract":"<div><p>Accurate preoperative assessment of chondral pathology is crucial for the diagnosis and subsequent management of articular cartilage defects. Magnetic resonance imaging (MRI) is the mainstay for articular cartilage evaluation, defect characterization, and long-term monitoring of surgical outcomes. In the absence of direct arthroscopic imaging, MRI serves as the most accurate modality for the assessment of cartilage defects. Recent studies have focused on the discrepancies in diagnostic findings, which may arise when comparing MRI and arthroscopic imaging. This review focuses on describing the differences between MRI and arthroscopic imaging findings in relation to cartilage injury. It also highlights the current understanding of normal cartilage histology, methods of cartilage defect evaluation, and expands on joint-specific considerations of the commonly imaged articulations.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"4 1","pages":"Article 100154"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254523000604/pdfft?md5=2fcce909a58b6c2b888acd2c05f83d5c&pid=1-s2.0-S2667254523000604-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124895697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cartilage injury patterns in the professional athlete","authors":"Mobeen Farooq,&nbsp;Christine Dan-Lantsman,&nbsp;Jeffrey A. Belair","doi":"10.1016/j.jcjp.2023.100148","DOIUrl":"10.1016/j.jcjp.2023.100148","url":null,"abstract":"<div><p>In this article, the authors review various types of cartilage injury patterns observed on magnetic resonance imaging (MRI) in professional athletes. Several examples of commonly injured joints are presented to showcase the importance of MRI in both the initial detection and characterization of cartilage lesions and the ensuing postoperative success of repair and/or restoration procedures in this unique patient population. Obtaining high-quality MRI studies, thoroughly understanding articular cartilage anatomy and pathology, and familiarizing oneself with the typical mechanisms of injury in various sports are of paramount importance to both radiologists and sports medicine clinicians alike. The authors aim to provide the reader with the foundational tools for approaching articular cartilage injuries in elite athletes and adding value to the diagnosis and treatment of these patients.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"4 1","pages":"Article 100148"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254523000549/pdfft?md5=25cb540b3dc8a550f3d868cc289d3a09&pid=1-s2.0-S2667254523000549-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116357081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging of cartilage damage","authors":"Colin Strickland ,&nbsp;Mohammad Ibrahim ,&nbsp;Eric McCarty","doi":"10.1016/j.jcjp.2023.100149","DOIUrl":"10.1016/j.jcjp.2023.100149","url":null,"abstract":"<div><h3>Introduction</h3><p>Cartilage damage is a common cause of joint pain and disability. Familiarity with common injury patterns and associated terminology is critical for appropriate treatment and communication.</p></div><div><h3>Objectives</h3><p>The goal of this narrative review is to describe the imaging features of cartilage damage and highlight the correlation with arthroscopic observation.</p></div><div><h3>Methods</h3><p>A systematic literature search via PubMed was performed using the search terms “Imaging, cartilage, damage, arthroscopy.” Abstracts were reviewed for relevance and appropriateness. Reviews and meta-analyses from recent years were used to identify additional useful resources.</p></div><div><h3>Results</h3><p>Recent original research studies and systematic reviews were utilized to construct an updated review of imaging findings and clinically useful terminology.</p></div><div><h3>Conclusions</h3><p>An understating of injury patterns and terminology bridging the arthroscopic and radiologic literature is an important basis of knowledge for clinical providers working in the realm of cartilage repair and joint preservation.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"4 1","pages":"Article 100149"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254523000550/pdfft?md5=bcbaa645dabdfa2c5629b402638fc9ea&pid=1-s2.0-S2667254523000550-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117102125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}