Journal of Cartilage & Joint Preservation最新文献

{"title":"Welcome to the third issue of JCJP 2025","authors":"Rachel M. Frank , Lucienne A. Vonk , Elizaveta Kon","doi":"10.1016/j.jcjp.2025.100259","DOIUrl":"10.1016/j.jcjp.2025.100259","url":null,"abstract":"","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"5 3","pages":"Article 100259"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144916825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-guided meniscal injection of autologous conditioned plasma: a case series at middle-term evaluation","authors":"Margherita Vacca ,&nbsp;Luca Ruosi ,&nbsp;Giulia Marcella Maryse Chiari Gaggia ,&nbsp;Beatrice Balzarini ,&nbsp;Giuseppe Anzillotti ,&nbsp;Pietro Conte ,&nbsp;Berardo Di Matteo ,&nbsp;Elizaveta Kon ,&nbsp;Daniele Altomare","doi":"10.1016/j.jcjp.2025.100242","DOIUrl":"10.1016/j.jcjp.2025.100242","url":null,"abstract":"<div><h3>Introduction</h3><div>Symptomatic degenerative meniscal tears are a tough challenge in daily clinical practice for orthopedic surgeons. Arthroscopic partial meniscectomy led to high cost, little improvement to Quality of Life and faster progression of OA. Thus, urgency for new conservative therapeutic strategies is emerging.</div></div><div><h3>Objectives</h3><div>To provide a report of the results of ultrasound (US)-guided intrameniscal injections with a solution of autologous conditioned plasma (ACP) in a group of active patients suffering of symptomatic degenerative meniscal tears.</div></div><div><h3>Methods</h3><div>Forty-seven patients were treated by 3 US-guided intra- and perimeniscal injections of ACP (Arthrex) at 2<!--> <!-->weeks interval, and prospectively assessed at baseline and at 12, 24 and then at final 36<!--> <!-->months’ follow-up, using Knee Injury and Osteoarthritis Outcome Score, International Knee Documentation Committee-subjective score, Visual Analog Scale, Tegner Activity Scale.</div></div><div><h3>Results</h3><div>Around two-thirds of the patients (32, 68.09%) declared to be satisfied by the procedure.</div><div>No correlation was found between age, sex, and body mass index and score variation, according to the multivariate analysis.</div><div>Thirty patients (63.8%) registered an increase of at least 10 points in Knee Injury and Osteoarthritis Outcome Score at 1<!--> <!-->year of follow-up, thus were identified as responder. Seventeen failures were reported (failure rate: 36%).</div></div><div><h3>Conclusions</h3><div>This study highlighted the potential benefit of an US-guided intrameniscal injective procedure using ACP for the management of symptomatic degenerative meniscal lesions. Further randomized controlled studies are needed to confirm the efficacy of ACP as a therapeutic option for degenerative meniscal tears.</div></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"5 3","pages":"Article 100242"},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144916741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Welcome to the second issue of JCJP 2025","authors":"Miranda Manfre,&nbsp;Rachel M. Frank","doi":"10.1016/j.jcjp.2025.100244","DOIUrl":"10.1016/j.jcjp.2025.100244","url":null,"abstract":"","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"5 2","pages":"Article 100244"},"PeriodicalIF":0.0,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of comorbid anxiety and major depression on functional outcomes in meniscectomy","authors":"Yusuf N. Mufti ,&nbsp;Jared P. Sachs ,&nbsp;David Christian ,&nbsp;Kevin Wang ,&nbsp;Allen Yazdi ,&nbsp;Fatima Bouftas ,&nbsp;Robert Gibbons ,&nbsp;Corey Goldstein ,&nbsp;Brian J. Cole","doi":"10.1016/j.jcjp.2025.100241","DOIUrl":"10.1016/j.jcjp.2025.100241","url":null,"abstract":"<div><h3>Introduction</h3><div>Psychiatric disorders such as depression and anxiety are prevalent but often unrecognized in orthopedic settings. While psychiatric conditions are known to affect functional outcomes in a variety of orthopedic procedures, limited data exist on their impact after meniscectomy.</div></div><div><h3>Objectives</h3><div>To evaluate the influence of comorbid anxiety and depression on pain and functional outcomes following meniscectomy.</div></div><div><h3>Methods</h3><div>Between August 2016 and January 2018, 141 patients scheduled for arthroscopic meniscectomy were prospectively recruited. Preoperatively, they completed the Computerized Adaptive Testing-Mental Health (CAT-MH) questionnaire, screening for major depressive disorder (MDD), anxiety, and mania. Functional outcome measures (IKDC, KOOS, SF12, VR12, and VR6D) were collected preoperatively and 6<!--> <!-->months postoperatively. Outcomes were compared between patients with and without MDD, and symptoms of anxiety and mania were correlated with outcome scores.</div></div><div><h3>Results</h3><div>Of the 141 patients, 120 completed the study. Thirteen patients (10.9%) screened positive for MDD, 10 (76.9%) of whom were female. Women reported lower levels of function on almost all measures. MDD-positive patients reported lower outcomes preoperatively and postoperatively. Higher anxiety levels were linked with lower baseline and postoperative scores. Both MDD-positive and -negative cohorts showed significant improvements in most outcome measures postoperatively. There was no difference in the extent of improvement between groups. Mania had no impact on outcomes.</div></div><div><h3>Conclusions</h3><div>Comorbid anxiety and depression were associated with worse preoperative and postoperative functional outcomes after meniscectomy, though both groups show similar improvement. These findings highlight the need for better mental health screening tools in orthopedics, as psychiatric conditions may disproportionately influence patient-reported outcomes.</div></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"5 3","pages":"Article 100241"},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144916740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of amniotic membrane in osteoarthritis management","authors":"Zuzana Macečková ,&nbsp;Jiří Pergner ,&nbsp;Martin Krbec ,&nbsp;Milan Urban ,&nbsp;Michal Zahradníček","doi":"10.1016/j.jcjp.2024.100174","DOIUrl":"10.1016/j.jcjp.2024.100174","url":null,"abstract":"<div><h3>Introduction</h3><div>Osteoarthritis (OA) is a prevalent degenerative joint disease characterized by articular cartilage degradation, inflammation, and pain. The current treatment options for OA are limited in their ability to provide long-term relief and restore joint function. However, recent advances in regenerative medicine have led to the exploration of alternative therapeutic strategies, including the application of amniotic membrane (AM) in OA management. AM has emerged as a promising therapeutic option due to its unique properties and regenerative potential, although the mechanism of action of AM in OA is not fully elucidated.</div></div><div><h3>Objectives</h3><div>Here, we discuss the anti-inflammatory, immunomodulatory, and regenerative properties of AM that make it an attractive candidate for OA treatment. Preclinical studies utilizing animal models have demonstrated the ability of AM to promote cartilage repair, reduce inflammation, and improve joint function. Clinical trials evaluating the safety and efficacy of AM-based therapies in OA patients have also shown promising results, with improvements in pain relief and functional outcomes.</div></div><div><h3>Conclusions</h3><div>In conclusion, while AM shows promise for OA management, additional studies and clinical trials are necessary to fully understand its therapeutic potential and establish it as a safe and effective treatment option for individuals with OA.</div></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"5 1","pages":"Article 100174"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140279765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autologous matrix-induced chondrogenesis versus osteochondral autograft transfer system in patellar chondral lesions: a comparative study with a 2-year follow-up","authors":"Pedro Debieux ,&nbsp;Marcos Vinicios Rodrigues dos Santos ,&nbsp;Diego da Costa Astur ,&nbsp;Seth Lawrence Sherman ,&nbsp;Moises Cohen ,&nbsp;Camila Cohen Kaleka","doi":"10.1016/j.jcjp.2024.100189","DOIUrl":"10.1016/j.jcjp.2024.100189","url":null,"abstract":"<div><h3>Introduction</h3><div>Focal patellofemoral chondral lesions are clinically challenging, with unfavorable surgical results in the medium- and long-term; Although there is no golden standard technique to treat patellofemoral lesions, several patellar cartilage repair procedures are used with variable postoperative results.</div></div><div><h3>Objectives</h3><div>To compare functional outcomes between patients who had undergone surgical treatment with osteochondral autograft transfer system (OATS) or autologous matrix-induced chondrogenesis (AMIC) for patellar chondral lesions preoperatively and after a 2-year follow-up.</div></div><div><h3>Methods</h3><div>Forty-six patients who underwent AMIC (<em>n</em> = 12) or OATS (<em>n</em> = 34), participated in this retrospective study. Outcome measures, including the Lysholm, Kujala, Fulkerson, and Tegner scores, were collected before surgery and 2 years after surgery.</div></div><div><h3>Results</h3><div>Sex, age, laterality, or location of the patellar lesion were not significantly different between groups. The mean lesion size was greater in the AMIC group (2.18 cm²) than in the OATS group (1.13 cm²) (<em>P</em> &lt; .001). There was no difference between groups in Lysholm, Fulkerson, and Kujala scores preoperatively, although the OATS group showed a more favorable Tegner score compared to the AMIC group (6.59 vs 3.45, <em>P</em> &lt; .001). Postoperatively, the AMIC group had a higher mean Lysholm score than the OATS group, (88.3 vs 79.5, <em>P</em> = .025). Mean values of almost all clinical tests significantly increased at the end of the 2-year follow-up, in both groups, except for the Tegner score in the OATS group, which showed a mean reduction from 6.59 preoperatively to 5.47 postoperatively (<em>P</em> = .006).</div></div><div><h3>Conclusion</h3><div>OATS and AMIC are effective treatments for patellar chondral lesions, with sustainable results after a minimum follow-up period of 2 years. Patients who underwent AMIC had better clinical and functional outcomes than patients who underwent OATS for patellar chondral lesions during the follow-up period.</div></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"5 1","pages":"Article 100189"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143547850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Welcome to the first issue of JCJP 2025","authors":"Miranda Manfre,&nbsp;Rachel M. Frank","doi":"10.1016/j.jcjp.2025.100238","DOIUrl":"10.1016/j.jcjp.2025.100238","url":null,"abstract":"","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"5 1","pages":"Article 100238"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143547984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patellofemoral stabilization with and without cartilage restoration","authors":"Joseph M. Rund ,&nbsp;John W. Welsh ,&nbsp;M. Benjamin Burch ,&nbsp;John R. Worley ,&nbsp;Lasun O. Oladeji ,&nbsp;Taylor Ray ,&nbsp;Aaron D. Gray ,&nbsp;Betina B. Hinckel ,&nbsp;Seth L. Sherman","doi":"10.1016/j.jcjp.2024.100190","DOIUrl":"10.1016/j.jcjp.2024.100190","url":null,"abstract":"<div><h3>Introduction/Objectives</h3><div>Cartilage restoration as an adjunct to patellofemoral (PF) soft tissue and/or bony stabilization in patients with symptomatic PF instability remains controversial. Our purpose was to evaluate patients undergoing surgical stabilization for PF instability with or without concomitant cartilage restoration.</div></div><div><h3>Methods</h3><div>Retrospective review of prospectively collected data identified patients undergoing surgical stabilization for recurrent patella instability, with or without concomitant cartilage restoration. Presurgical and postsurgical patient-reported outcomes were collected. Complications requiring reoperation were recorded. Statistically significant difference was set at <em>P</em> &lt; .05.</div></div><div><h3>Results</h3><div>One hundred thirty patients (144 knees) were included. One hundred thirteen knees in the isolated stabilization (STAB) and 31 knees in the Stabilization-Cartilage Restoration (STAB-CART) group. The average age was 20.64 and 25.03 in the STAB and STAB-CART groups (<em>P</em> = .034), respectively. STAB-CART group had significantly lower preoperative Knee injury and Osteoarthritis Outcomes Score (57.24 ± 17.45 vs 46.11 ± 14.74, <em>P</em> = .019) and Single Assessment Numeric Evaluation scores (43.15 ± 19.05 vs 26.85 ± 13.74, <em>P</em> = .002). Both groups statistically improved in all Knee injury and Osteoarthritis Outcomes Score, International Knee Documentation Committee, and Single Assessment Numeric Evaluation domains with no statistically significant differences at final follow-up between groups. Thirteen knees (11.5%) in the STAB and 6 knees (19.4%) in the STAB-CART group had complications requiring reoperation, including 6 and 3 revision stabilizations, respectively. There were no statistically significant differences in total major complications (<em>P</em> = .246) or medial PF ligament revision (<em>P</em> = .405).</div></div><div><h3>Conclusions</h3><div>The addition of cartilage restoration in patients undergoing soft tissue and/or bony PF stabilization appears to be safe and effective. Despite lower baseline scores, patients undergoing PF stabilization with cartilage restoration had similar final subjective outcome scores compared to the group without.</div></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"5 1","pages":"Article 100190"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143547812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe acute localized reactions after intra-articular hyaluronic acid injections: a narrative review and physician’s guide to incidence, prevention, and management of these adverse reactions","authors":"David Humphries ,&nbsp;Michael Baria ,&nbsp;Jane Fitzpatrick","doi":"10.1016/j.jcjp.2024.100187","DOIUrl":"10.1016/j.jcjp.2024.100187","url":null,"abstract":"<div><h3>Introduction</h3><div>Hyaluronic acids (HAs) are commonly used in osteoarthritis. Whilst adverse events are infrequent, the most common is pain and swelling of the joint.</div></div><div><h3>Objectives and Methods</h3><div>A narrative review of the incidence and causes of severe acute localized reactions (SALR) with insights into the prevention and management of SALR.</div></div><div><h3>Results</h3><div>SALR refers to the onset of acute arthralgia, associated swelling, erythema, and motion restriction, after the intra-articular injection of HA. The onset of symptoms is between 4 hours and several days. SALR appears to be immunological responses to the HA and related to poor injection techniques. This literature review identifies that the incidence of SALR following intra-articular injection of HA is relatively low but is not rare. Thus, clinicians using intra-articular HA injections can expect to see patients with SALR and should be prepared to diagnose and treat SALR. The risk of SALR appears to be independent of the source of HA (avian or bacterial fermentation) and the use of crosslinking of the HA product.</div></div><div><h3>Conclusions</h3><div>Intra-articular HA injections are relatively common treatments for the symptoms of osteoarthritis, where primary interventions have been ineffective. Whilst the risk of complications from such injections is low, both mild and more SALR do occur. The reactions can be mitigated by the careful selection of injection portal and the use of ultrasound guidance. Once the differential diagnosis of septic arthritis is excluded, the management of a SALR will generally consist of reassurance and simple analgesia, with more severe cases requiring nonsteroidal anti-inflammatory medication or intra-articular corticosteroids.</div></div><div><h3>What is known about this topic</h3><div>Hyaluronic acids have been used in the management of osteoarthritis for over 3 decades. Whilst adverse events are infrequent, the most common is pain and swelling of the joint, which when severe are termed severe acute localized reactions (SALR) or pseudo-sepsis.</div></div><div><h3>What this study adds</h3><div>This paper provides the injecting physician with a narrative review of the incidence and causes of SALR, insights into the prevention and a discussion of the management.</div></div><div><h3>How might this affect research practice or policy?</h3><div>This information will allow clinicians to mitigate the risks of triggering a SALR and provides a clear pathway for management if such an event occurs. Additionally, it informs the creation of specific policies around the use of HA injections.</div></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"5 1","pages":"Article 100187"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140769038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biointegrative fiber-reinforced implants for fixation of subchondral insufficiency with avascular necrosis: a case report","authors":"Sarah A. Muth,&nbsp;Alexander C. Weissman,&nbsp;Allen A. Yazdi,&nbsp;Katie J. McMorrow,&nbsp;Richard M. Danilkowicz,&nbsp;Brian J. Cole","doi":"10.1016/j.jcjp.2024.100171","DOIUrl":"10.1016/j.jcjp.2024.100171","url":null,"abstract":"<div><h3>Introduction</h3><div>Treating avascular necrosis (AVN) of the knee can be challenging, particularly at later stages of progression. After subchondral collapse occurs, the only existing surgical treatment is arthroplasty. In earlier stages of collapse, joint sparing procedures for the treatment of AVN include core decompression, osteotomy with metallic implant fixation, and osteochondral grafting. However, there are no reported cases of using biointegrative nails to directly treat subchondral insufficiency of the femoral condyle due to AVN.</div></div><div><h3>Case presentation</h3><div>In this case, the patient suffered from lateral-sided knee pain and swelling, which affected mobility and activities of daily living. At 6 months postoperatively, following subchondral cortex to cortex implantation of 2 biointegrative nails, the patient achieved full range of motion, and at 1 year, magnetic resonance imaging (MRI) showed improved resolution of edema and bone remodeling around the biointegrative nails.</div></div><div><h3>Conclusion</h3><div>In this case report, we demonstrate a new surgical approach to the treatment of subchondral insufficiency due to AVN. Although the outcomes are positive, a larger sample size should be evaluated for the efficacy of treatment of AVN with biointegrative nails.</div></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"5 1","pages":"Article 100171"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140278887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}