Biointegrative fiber-reinforced implants for fixation of subchondral insufficiency with avascular necrosis: a case report

Sarah A. Muth, Alexander C. Weissman, Allen A. Yazdi, Katie J. McMorrow, Richard M. Danilkowicz, Brian J. Cole
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Abstract

Introduction

Treating avascular necrosis (AVN) of the knee can be challenging, particularly at later stages of progression. After subchondral collapse occurs, the only existing surgical treatment is arthroplasty. In earlier stages of collapse, joint sparing procedures for the treatment of AVN include core decompression, osteotomy with metallic implant fixation, and osteochondral grafting. However, there are no reported cases of using biointegrative nails to directly treat subchondral insufficiency of the femoral condyle due to AVN.

Case presentation

In this case, the patient suffered from lateral-sided knee pain and swelling, which affected mobility and activities of daily living. At 6 months postoperatively, following subchondral cortex to cortex implantation of 2 biointegrative nails, the patient achieved full range of motion, and at 1 year, magnetic resonance imaging (MRI) showed improved resolution of edema and bone remodeling around the biointegrative nails.

Conclusion

In this case report, we demonstrate a new surgical approach to the treatment of subchondral insufficiency due to AVN. Although the outcomes are positive, a larger sample size should be evaluated for the efficacy of treatment of AVN with biointegrative nails.
用于固定软骨下缺损伴血管性坏死的生物合成纤维增强植入物:病例报告
治疗膝关节缺血性坏死(AVN)具有挑战性,特别是在进展的后期。发生软骨下塌陷后,现有的唯一手术治疗方法是关节置换术。在塌陷的早期阶段,治疗AVN的关节保留手术包括核心减压、金属植入固定截骨和骨软骨移植。然而,目前还没有使用生物整合钉直接治疗AVN引起的股骨髁软骨下功能不全的病例报道。病例表现:患者出现外侧膝关节疼痛和肿胀,影响了日常生活的活动和活动。术后6个月,在软骨下皮质到皮质植入2枚生物整合钉后,患者实现了全活动范围,1年后,磁共振成像(MRI)显示生物整合钉周围水肿和骨重塑的分辨率有所改善。结论在本病例报告中,我们展示了一种新的手术方法来治疗AVN引起的软骨下功能不全。虽然结果是积极的,但更大的样本量应该评估生物整合钉治疗AVN的疗效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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