Hybrid Advances最新文献

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Metal-based nanoparticles and nanohybrids for sensing and remediation of environmental pesticides 金属基纳米粒子和纳米杂交种用于环境农药的传感和修复
Hybrid Advances Pub Date : 2025-04-15 DOI: 10.1016/j.hybadv.2025.100485
Prem Rajak
{"title":"Metal-based nanoparticles and nanohybrids for sensing and remediation of environmental pesticides","authors":"Prem Rajak","doi":"10.1016/j.hybadv.2025.100485","DOIUrl":"10.1016/j.hybadv.2025.100485","url":null,"abstract":"<div><div>Nanotechnology is an emerging field in engineering, health science, and environmental management. Recent studies have advocated the potential scope of nanoparticles and nanohybrids in pesticide sensing and removal from environmental samples. Metal oxide nanoparticles, metallic and bimetallic nanoparticles, halloysite, and carbon nanotubes have shown their efficacy in pesticide remediation. These materials can be coupled with conventional colorimetric, Surface Plasmon Resonance, fluorescence-based, aptameric, and enzyme-based approaches to detect pesticides belonging to organophosphate, organochlorine, carbamate, neonicotinoid, and atrazine groups. Degradation mechanisms like hydrolysis, photocatalysis, oxidation, and ozonation are employed by nanotechnology to remove pesticides from water and soil samples. However, certain issues like scalability, unavailability of rigorous testing protocols, and lack of uniform regulatory frameworks for nanomaterial synthesis limit its usage. Moreover, toxicity profiles of the majority of nanomaterials are lacking. Studies indicate that nanomaterials can be cytotoxic. Therefore, safety is another major concern. Hence, the present review aims to discuss the recent advances in nanoparticle and nanohybrid-mediated sensing and the removal of pesticides from real samples. Moreover, the chemistry behind pesticide sensing and removal will also be delineated. Finally, the review sheds light on existing limitations associated with nanomaterial-based pesticide sensing and remediation at the global scale.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"10 ","pages":"Article 100485"},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143851944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A hydrophobic flexible self-cleaning carbon based type II heterojunction photocatalyst:A smart apparel for multifunctional application 一种疏水柔性自清洁碳基II型异质结光催化剂:一种多功能智能服装
Hybrid Advances Pub Date : 2025-04-15 DOI: 10.1016/j.hybadv.2025.100486
Srimathi Krishnaswamy , Puspamitra Panigrahi , Praseetha Prabhakaran Kala , Sharon Sofini , Ganapathi Subramaniam Nagarajan
{"title":"A hydrophobic flexible self-cleaning carbon based type II heterojunction photocatalyst:A smart apparel for multifunctional application","authors":"Srimathi Krishnaswamy ,&nbsp;Puspamitra Panigrahi ,&nbsp;Praseetha Prabhakaran Kala ,&nbsp;Sharon Sofini ,&nbsp;Ganapathi Subramaniam Nagarajan","doi":"10.1016/j.hybadv.2025.100486","DOIUrl":"10.1016/j.hybadv.2025.100486","url":null,"abstract":"<div><div>Graphitic carbon nitride(GCN) and polypyrrole(PPy) based smart apparel were fabricated using polyvinyl alcohol as a binder on cotton cloth. Equal amount of GCN and PPy were mixed with different weight percentages to form composites and fabricated the thin film by casting method. A higher weight percentage of composite thin film revealed a low bandgap (3.555 eV) garnering 50 % of solar light. Higher optical(0.1735S) and electrical conductivity (1.4234X10<sup>−3</sup> S/cm) was noticed for 5 GP. The nitrogen defect center of GCN was blocked by the –NH group of PPy and reduced the PL quenching of GCN. As 5 GP possesses, higher conductivity, it was chosen to fabricate smart attires. The smart fabric exhibited lower water solubility(10 %) and lower water absorption(30 %) and higher contact angle (110.8°) and revealed that the material is hydrophobic in nature. Owing to the hydrophobic nature and wide absorption, it can be a candidate for self-cleaning apparel.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"10 ","pages":"Article 100486"},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143850533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inclusive analysis of Mn3O4 nanostructures: Dual-functional materials for dielectric and supercapacitor applications Mn3O4纳米结构的包容性分析:用于电介质和超级电容器的双功能材料
Hybrid Advances Pub Date : 2025-04-15 DOI: 10.1016/j.hybadv.2025.100490
Clement Varaprasad Karu , Dadamiah PMD Shaik , Nageswara Rao Lakkimsetty
{"title":"Inclusive analysis of Mn3O4 nanostructures: Dual-functional materials for dielectric and supercapacitor applications","authors":"Clement Varaprasad Karu ,&nbsp;Dadamiah PMD Shaik ,&nbsp;Nageswara Rao Lakkimsetty","doi":"10.1016/j.hybadv.2025.100490","DOIUrl":"10.1016/j.hybadv.2025.100490","url":null,"abstract":"<div><div>Using extracts from medicinal plants, Mn<sub>3</sub>O<sub>4</sub> microstructures were effectively created by a green synthesis method. The produced and pellet samples' structural and electrochemical characteristics were thoroughly examined. X-ray diffraction (XRD) investigation showed an estimated crystallite size of 39 and 43 nm with a prominent (211) orientation peak at 2θ = 36.1°, which corresponds to the tetragonal crystal structure of Mn<sub>3</sub>O<sub>4</sub> with space group <em>I</em>4<sub>1</sub>/<em>amd</em>(141)). Analysis using scanning electron microscopy (SEM) revealed an average grain size of roughly 500 nm. The presence of Mn–O bonds in the produced material was further validated by Raman spectroscopy. Within a temperature range of ambient temperature to 373 K, the impedance characteristics of the Mn<sub>3</sub>O<sub>4</sub> samples were studied throughout a frequency range of 1 Hz to 1 MHz. The conductivity of electricity showed an Arrhenius-like increase with temperature, with an estimated activation energy of 0.39 eV and a conductivity value of 7.42 × 10<sup>−4</sup> S/cm at 373 K. The dielectric characteristics, such as dielectric loss and dielectric constant, were assessed in the same frequency range and at temperatures between 303 and 373 K. The Mn<sub>3</sub>O<sub>4</sub> nanostructures showed a specific capacitance of 284 F/g at a scan rate of 0.5 A/g in 1 M Li<sub>2</sub>SO<sub>4</sub> aqueous electrolyte and a capacitive retention of 81 % even after 3000 cycles. According to these findings, the produced Mn<sub>3</sub>O<sub>4</sub> nanoparticles show a great deal of promise for use in supercapacitors.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"10 ","pages":"Article 100490"},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A biocompatible nitinol based triboelectric stent sensor for prospective cardiovascular health monitoring 用于前瞻性心血管健康监测的生物相容性镍钛诺基摩擦电支架传感器
Hybrid Advances Pub Date : 2025-04-10 DOI: 10.1016/j.hybadv.2025.100484
Ulises Vidaurri Romero , Sk Shamim Hasan Abir , Najlah Karam , Mariana Torres , Shahria Ahmed , Md. Wasikur Rahman , Bahareh Azimi , Serena Danti , Jianzhi Li , Mohammed Jasim Uddin
{"title":"A biocompatible nitinol based triboelectric stent sensor for prospective cardiovascular health monitoring","authors":"Ulises Vidaurri Romero ,&nbsp;Sk Shamim Hasan Abir ,&nbsp;Najlah Karam ,&nbsp;Mariana Torres ,&nbsp;Shahria Ahmed ,&nbsp;Md. Wasikur Rahman ,&nbsp;Bahareh Azimi ,&nbsp;Serena Danti ,&nbsp;Jianzhi Li ,&nbsp;Mohammed Jasim Uddin","doi":"10.1016/j.hybadv.2025.100484","DOIUrl":"10.1016/j.hybadv.2025.100484","url":null,"abstract":"<div><div>Triboelectric nanogenerators (TENGs) have been considered as an effective approach for self-powered systems. Currently, coronary heart disease remains the leading cause of death in the United States. This can be easily resolved by balloon angioplasty or a specialized mesh tube called a stent. This study demonstrates a stent sensor made of nitinol, a nickel—titanium alloy used in the medical field for its pseudo-elasticity and strong corrosion resistance, poly(vinylidene fluoride) (PVDF) and polydimethylsiloxane (PDMS), which can measure several physiological parameters while placing it in the arteries. This nitinol health monitor sensor (NHMS) device thus integrates the TENG with a specific medical application. The NHMS possesses memory shape nitinol electrodes that preserve the device structure, while using PDMS and PVDF triboelectric effect to measure heart rate, blood pressure and breathing patterns. Three constant pressures were measured in this study. At a constant pressure of stage 1 (5 psi), stage 2 (11 psi) and stage 3 (13 psi), the NHMS produces an average alternating current (AC) of 0.31 V, 0.49 V and 0.71 V, respectively. Several beats per minute (bpm) were measured and clear readings were obtained from 30 bpm to 180 bpm. Additionally, this device was able to charge a commercial capacitor, which shows its performance as a self-powered sensor, thus holding great potential in medical applications.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"10 ","pages":"Article 100484"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143839783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanofluidic innovations and advances in fabrication of lab-on-a-chip systems in health care to bridge nanoengineering and medicine 纳米流控技术在医疗保健芯片实验室系统制造中的创新与进展,为纳米工程与医学搭建桥梁
Hybrid Advances Pub Date : 2025-04-10 DOI: 10.1016/j.hybadv.2025.100459
Sucharitha Palagati , Ramesh Reddy Kudamala , Kishore Bandarapalle , Jayasankar Reddy Veeram , Bhaskar Reddy Kesavan
{"title":"Nanofluidic innovations and advances in fabrication of lab-on-a-chip systems in health care to bridge nanoengineering and medicine","authors":"Sucharitha Palagati ,&nbsp;Ramesh Reddy Kudamala ,&nbsp;Kishore Bandarapalle ,&nbsp;Jayasankar Reddy Veeram ,&nbsp;Bhaskar Reddy Kesavan","doi":"10.1016/j.hybadv.2025.100459","DOIUrl":"10.1016/j.hybadv.2025.100459","url":null,"abstract":"<div><div>The field of nanofluidics is advancing significantly in lab-on-a-chip applications, where the unique properties of nanoscale matter enhance devices using nanopores or nanochannels. Innovations in nanofabrication have led to advanced nanofluidic systems that consolidate multiple processing steps into single devices, referred to as “labs-on-a-chip” or “micro total analysis systems.” Nanofluidics and lab-on-a-chip technologies are transforming the way we process and examine small quantities of fluids. These innovations abridge entire laboratories into compact chips, enabling quicker, more economical, and more accurate experiments and analyses. By controlling fluids at the nanoscale, researchers can leverage distinctive physical properties to create novel applications. In a way to foster disease diagnostics to cutting-edge drug development, these miniature devices are significantly influencing health care as personalised medical tools. This article highlights advancements in integrated micro- and nanofluidic devices, illustrating how nanochannels can enhance various functions in chemical analysis, such as sample preparation, fluid handling, separation, and detection. It also addresses challenges faced by these systems, particularly in efficient sample preparation processes like filtration and cell lysis. The development of artificial nanochannels aims to overcome technical hurdles in creating durable protein pore sensors. Despite potential applications, the adoption of novel nanofluidic devices has been slow, partly due to the gap between device development and commercialization. To establish a pipeline of promising technologies, challenges like system integration, cost, regulatory approval, and clinical acceptance must be addressed.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"10 ","pages":"Article 100459"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143924178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent trends in the plant based metal oxide nanoparticles and their application in biomedical and waste water remediation - A review 植物基金属氧化物纳米颗粒及其在生物医学和废水修复中的应用研究进展
Hybrid Advances Pub Date : 2025-04-10 DOI: 10.1016/j.hybadv.2025.100475
Sandeep Kumar , Manish Kumar , Vinay Chauhan , Deepika Kaushal
{"title":"Recent trends in the plant based metal oxide nanoparticles and their application in biomedical and waste water remediation - A review","authors":"Sandeep Kumar ,&nbsp;Manish Kumar ,&nbsp;Vinay Chauhan ,&nbsp;Deepika Kaushal","doi":"10.1016/j.hybadv.2025.100475","DOIUrl":"10.1016/j.hybadv.2025.100475","url":null,"abstract":"<div><div>Nanomaterials (NMs) are gradually revolutionizing our world. They are playing an increasingly vital role across various fields, from everyday products to advanced technology. Nanoparticles (NPs) differ from bulk materials due to their high surface-area-to-volume ratio, which significantly influences their physical properties and reactivity. Metal oxide NPs possess unique characteristics, including a tunable band gap, making them suitable for diverse applications. The demand for environmentally friendly synthesis methods is growing, as green approaches offer a sustainable and cost-effective alternative for NP production. While gold and silver NPs have been widely studied, their high-cost limits large-scale applications. In contrast, metal oxide NPs of first-transition-series elements provide a more economical option. This review explores the green synthesis of these NPs and their applications, particularly in antibacterial treatments and water remediation, highlighting their potential as sustainable solutions for environmental and biomedical challenges.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"10 ","pages":"Article 100475"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143825787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanical performance of as-built and heat-treated Inconel 625 additively manufactured by L-DED with different build orientations L-DED增材制造不同构建取向的铸态和热处理Inconel 625的力学性能
Hybrid Advances Pub Date : 2025-04-10 DOI: 10.1016/j.hybadv.2025.100478
Juliane Ribeiro da Cruz , Henrique Santos Ferreira , Anselmo Thiesen Jr. , Jurandir Marcos Sá de Sousa
{"title":"Mechanical performance of as-built and heat-treated Inconel 625 additively manufactured by L-DED with different build orientations","authors":"Juliane Ribeiro da Cruz ,&nbsp;Henrique Santos Ferreira ,&nbsp;Anselmo Thiesen Jr. ,&nbsp;Jurandir Marcos Sá de Sousa","doi":"10.1016/j.hybadv.2025.100478","DOIUrl":"10.1016/j.hybadv.2025.100478","url":null,"abstract":"<div><div>Additive manufacturing of the Ni-based Inconel 625 superalloy, as an alternative to conventional methods, is of interest to produce near-net-shape parts, due to this alloy's intrinsic high abrasiveness and poor machinability. Because of the complex thermal history of L-DED AM, post processing heat-treatments are often required for stress relief and microstructure homogenization. This work investigates the mechanical performance of Inconel 625 specimens manufactured by laser directed energy deposition (L-DED) in the as-built and heat-treated conditions (900 °C for 2 h). Microstructure was characterized by optical and scanning electron microscopy with energy dispersive spectroscopy. Mechanical properties were assessed by Vickers hardness, tensile, and Charpy impact tests. The effects of build orientation and heat-treatment were discussed, and results were benchmarked to those of commercial Inconel 625 reported in the literature. Results show that the as-built samples developed a columnar dendritic microstructure with epitaxial grain growth, and the presence of Mo, Nb, and Si-rich interdendritic Laves phase. The post processing heat-treatment led to partial recrystallization and formation of Laves phase and carbides at grain boundaries, which caused a Charpy energy absorption reduction of about 40 % compared with the as-built condition. This behavior was similar to that observed for the wrought Inconel 625. Under tensile solicitations, the grain boundary embrittlement decreased the total elongation but did not compromise yield strength and ultimate tensile strength, which remained superior to those expected from Ni–Cr–Mo–Nb alloys, as reported by ASTM <span><span>B446-24</span><svg><path></path></svg></span>. Slightly superior hardness, yield strength, and ultimate tensile strength were found for horizontally built specimens. This outcome is associated with its higher cooling rates and microstructure refinement.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"10 ","pages":"Article 100478"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143834424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application or function of cyclodextrin in insulin and cell delivery for efficient diabetic treatment 环糊精在胰岛素和细胞传递中的应用或功能,有效治疗糖尿病
Hybrid Advances Pub Date : 2025-04-10 DOI: 10.1016/j.hybadv.2025.100462
Siamak Javanbakht , Hossein Poursadegh , Sima Darvishi , Ali Mohammadzadeh , Ayda Saboury , Marjan Joulaei , Reza Mohammadi
{"title":"Application or function of cyclodextrin in insulin and cell delivery for efficient diabetic treatment","authors":"Siamak Javanbakht ,&nbsp;Hossein Poursadegh ,&nbsp;Sima Darvishi ,&nbsp;Ali Mohammadzadeh ,&nbsp;Ayda Saboury ,&nbsp;Marjan Joulaei ,&nbsp;Reza Mohammadi","doi":"10.1016/j.hybadv.2025.100462","DOIUrl":"10.1016/j.hybadv.2025.100462","url":null,"abstract":"<div><div>Diabetes mellitus (DM) poses a significant global health challenge, with escalating prevalence rates and associated complications necessitating urgent attention. Traditional insulin delivery methods, such as multiple daily subcutaneous injections, present challenges in terms of patient compliance and efficacy. Consequently, there is a growing interest in alternative insulin delivery systems. Cyclodextrins (CDs), owing to their unique molecular structure and adaptable properties, have emerged as promising excipients for insulin delivery. By forming inclusion complexes, CDs enhance the stability, solubility, and bioavailability of insulin formulations, thereby improving their efficacy in blood glucose regulation. Recent research has explored various routes of administration for cyclodextrin-complexed insulin formulations, including mucosal and oral delivery, offering novel strategies for enhanced glycemic control. Encapsulation of insulin within cyclodextrin-based carriers, such as mucoadhesive nanoparticles, represents a particularly innovative approach with the potential to revolutionize diabetes treatment. The utilization of cyclodextrins in insulin and cell delivery signifies a significant advance in pharmaceutical research, promising to optimize therapeutic outcomes and enhance the quality of life for individuals living with diabetes. As the global burden of diabetes continues to rise, the development of alternative insulin delivery systems becomes increasingly imperative, and cyclodextrins offer a promising avenue for addressing this pressing healthcare need.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"10 ","pages":"Article 100462"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancements in DNA nanotechnology for targeted drug delivery: Design strategies and applications 靶向药物递送的DNA纳米技术进展:设计策略和应用
Hybrid Advances Pub Date : 2025-04-08 DOI: 10.1016/j.hybadv.2025.100480
Pratikeswar Panda, Rajaram Mohapatra
{"title":"Advancements in DNA nanotechnology for targeted drug delivery: Design strategies and applications","authors":"Pratikeswar Panda,&nbsp;Rajaram Mohapatra","doi":"10.1016/j.hybadv.2025.100480","DOIUrl":"10.1016/j.hybadv.2025.100480","url":null,"abstract":"<div><div>DNA nanotechnology has emerged as a promising strategy for designing drug delivery systems that are safe, non-immunogenic, biodegradable, non-toxic, and biocompatible. When employed as drug carriers, DNA nanostructures offer several advantages, including precise programmability, scalable synthesis under optimized conditions, high structural consistency, and customizable control over size, shape, and functionality. Their programmability arises from predictable Watson-Crick base pairing, enabling the rational design of complex nanostructures with superior precision compared to conventional synthetic nanoparticles or polymeric carriers. While large-scale DNA synthesis can be costly, advancements in enzymatic synthesis and high-throughput oligonucleotide production have demonstrated cost-reduction potential relative to certain polymeric or lipid-based nanocarriers. DNA nanostructures can enhance therapeutic efficacy, minimize cytotoxicity in healthy tissues, and improve the bioavailability of poorly soluble drugs. By conjugating them with functional elements—such as polymers, peptides, lipids, proteins, inorganic nanoparticles, and targeting ligands—via diverse bioconjugation strategies, their stability can be improved, circulation time extended, and targeted drug delivery efficiency optimized. Furthermore, smart DNA nanostructures equipped with targeting moieties or stimuli-responsive elements enable precise drug release, minimizing premature leakage and off-target effects. These advanced nanocarriers facilitate drug accumulation at target sites, enhance cellular uptake, bypass efflux mechanisms, and mitigate adverse reactions. By refining drug dispersion and release kinetics, they accelerate therapeutic action and improve overall treatment outcomes. This study explores the potential of DNA nanostructures in drug encapsulation and targeted delivery, highlighting their advantages over conventional nanocarrier systems.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"10 ","pages":"Article 100480"},"PeriodicalIF":0.0,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143814802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis of TiO2 and Ag/Cu doped TiO2 nanoparticles in green approach and assess their structural, morphological, and photocatalytic applications 绿色途径合成TiO2和Ag/Cu掺杂TiO2纳米粒子,并评估其结构、形态和光催化应用
Hybrid Advances Pub Date : 2025-04-08 DOI: 10.1016/j.hybadv.2025.100468
Dnyaneshwar G. Mali , Sandip P. Patil , Gunvant H. Sonawane , Bhagwan S. Bhadane , Vilas K. Mahajan
{"title":"Synthesis of TiO2 and Ag/Cu doped TiO2 nanoparticles in green approach and assess their structural, morphological, and photocatalytic applications","authors":"Dnyaneshwar G. Mali ,&nbsp;Sandip P. Patil ,&nbsp;Gunvant H. Sonawane ,&nbsp;Bhagwan S. Bhadane ,&nbsp;Vilas K. Mahajan","doi":"10.1016/j.hybadv.2025.100468","DOIUrl":"10.1016/j.hybadv.2025.100468","url":null,"abstract":"<div><div>For environmental protection, developing efficient materials and techniques for pollutant elimination is vital. In the present study, the economically cheap, sustainable, green TiO<sub>2</sub> and Ag/Cu doped TiO<sub>2</sub> nanoparticles synthesized were using mulberry plant leaf extract. The Morphological characterization of TiO<sub>2</sub> nanoparticles, including undoped and Ag/Cu doped TiO<sub>2</sub> nanocatalyst was conducted using X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDS), and scanning electron microscopy (SEM) techniques. Their functional group characterization will have done by Fourier transform infrared spectroscopy (FT-IR) and band gap study done by UV–visible spectroscopy. Photocatalytic performance was assessed by monitoring the degradation of methylene blue sample solution under sunlight radiation. Investigations were conducted into the effects of different experimental factors on photocatalytic degradation such as variable pH, dye concentration, contact time, and catalyst dosage. The kinetics study shows that first order reaction. While comparing 1 %, 2 %, and 3 % Ag/Cu doped TiO<sub>2</sub> nanocatalyst and undoped TiO<sub>2</sub> nanocatalyst, it was shown that the latter exhibited the maximum degradation under sunlight radiation while using methylene blue as an organic pollutant. The greenly synthesized 3 % Ag doped TiO<sub>2</sub> nanocatalyst shows the maximum photocatalytic degradation of methylene blue reached a remarkable efficiency of 98.55 % after 90 min of exposure to sunlight radiation according to photocatalytic degradation because of a low band gap compared to Cu doped TiO<sub>2</sub> and undoped TiO<sub>2</sub>, according to photocatalytic degradation analysis. The degradation percentages are 3 % Ag-doped TiO<sub>2</sub> - 98.55, 2 % Ag-doped TiO<sub>2</sub> - 95.78 %, 1 % Ag-doped TiO<sub>2</sub> - 93.33 %, 3 % Cu-doped TiO<sub>2</sub> - 93.54 %,2 % Cu-doped TiO<sub>2-</sub>87.33 %, 1 % Cu-doped TiO<sub>2</sub> - 79.00 % and undoped TiO<sub>2</sub> - 77.75 % respectively. The reusability of the catalyst also studied up to 4 cycles. TiO<sub>2</sub> and Ag/Cu doped TiO<sub>2</sub> nanocatalysts demonstrate effective activity, which is beneficial for water purification and environmentally friendly applications.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"10 ","pages":"Article 100468"},"PeriodicalIF":0.0,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143821555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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