{"title":"Guest Editor's Introduction: Infectious diseases of the skin","authors":"Stephen K. Tyring","doi":"10.1002/der2.228","DOIUrl":"https://doi.org/10.1002/der2.228","url":null,"abstract":"","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"5 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140619806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Viral diseases affecting the skin","authors":"Chelsea M. Gerlicki","doi":"10.1002/der2.225","DOIUrl":"https://doi.org/10.1002/der2.225","url":null,"abstract":"<p>This chapter delves into the complex world of viral exanthems, focusing on their diagnostic challenges and distinctive features, with updated presentations and pearls. From Roseola Infantum's atypical fever-rash presentation to Rubeola's resurgence, it underscores the importance of prompt diagnosis. Rubella, frequently confused with measles, demands heightened suspicion, especially in adults and pregnant patients. Hand, Foot, and Mouth Disease's diverse manifestations warrant accurate differentiation. The discussion extends to Parvovirus B19, Varicella-Zoster Virus, Epstein-Barr Virus, and HIV Primary Infection. The resurgence of Mpox, Zika Virus's risks during pregnancy, and the rare but life-threatening Eczema Herpeticum are explored. Gianotti-Crosti Syndrome, Unilateral Laterothoracic Exanthem, and other viral conditions complete the landscape. In summary, this chapter offers a comprehensive understanding of viral exanthems, enabling clinicians to distinguish and manage these dermatological challenges. Accurate identification is crucial for providing specialized therapy to a minority of cases and supportive care to the majority. Vigilance, thorough examination, and a nuanced understanding of viral presentations are essential in navigating this intricate landscape.</p>","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/der2.225","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139739284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kevin M. Burningham, Juliana H. Kim, Alisha Kashyap, Stephen K. Tyring
{"title":"A clinical update on fungal disease of human skin","authors":"Kevin M. Burningham, Juliana H. Kim, Alisha Kashyap, Stephen K. Tyring","doi":"10.1002/der2.224","DOIUrl":"https://doi.org/10.1002/der2.224","url":null,"abstract":"<p>Fungi cause cutaneous pathology in humans in three broad categories: superficial mycoses, subcutaneous mycoses, and systemic or opportunistic mycoses. In this chapter, we will discuss recent updates in treatment for dermatological diagnoses in each of these categories. We will also discuss dermatologically relevant emerging fungal pathogens.</p>","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hamza Malick, Sheeva Shahinfar, Mohamad Jabin, Kevin M. Burningham, Mojahed M. K. Shalabi, Stephen K. Tyring
{"title":"Emerging skin infections: A clinical update","authors":"Hamza Malick, Sheeva Shahinfar, Mohamad Jabin, Kevin M. Burningham, Mojahed M. K. Shalabi, Stephen K. Tyring","doi":"10.1002/der2.222","DOIUrl":"10.1002/der2.222","url":null,"abstract":"","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139007779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ramlah Khan, Hamza Malick, Kevin M. Burningham, Mojahed M. K. Shalabi, Stephen K. Tyring
{"title":"COVID-19 and skin manifestations","authors":"Ramlah Khan, Hamza Malick, Kevin M. Burningham, Mojahed M. K. Shalabi, Stephen K. Tyring","doi":"10.1002/der2.221","DOIUrl":"10.1002/der2.221","url":null,"abstract":"","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139008045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamad Jabin, Yousef Salem, Kevin Burningham, Mojahed Mohammad K. Shalabi, Stephen K. Tyring
{"title":"Arthropods and the skin","authors":"Mohamad Jabin, Yousef Salem, Kevin Burningham, Mojahed Mohammad K. Shalabi, Stephen K. Tyring","doi":"10.1002/der2.220","DOIUrl":"10.1002/der2.220","url":null,"abstract":"<p>Arthropods are responsible for most of the animal-related emergency room visits each year, and nonvenomous arthropods cause the greatest number of animal-related deaths in the emergency setting. Physicians should recognize the sequela of common and lethal arthropod bites and stings as they can range from asymptomatic or mild pruritus to fatal anaphylactic reactions. This chapter provides an update on recent advancements in the dermatological manifestations, pathophysiology, and management of conditions caused by arthropod bites and stings. Key topics include emerging treatments for pediculosis, characteristic rashes of mosquito-borne viral diseases, cutaneous lesions in Chagas disease, new Lyme disease vaccine development, topical Spinosad for scabies, and Loxosceles venom composition and early use of antivenom. Recent research reveals progress in understanding arthropod-related dermatologic diseases but also persistent knowledge gaps in the literature. This focused update delivers a concise overview of current concepts and developments at the intersection of arthropods and dermatology for clinicians.</p>","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138616017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The future of cosmeceuticals","authors":"Maya Firsowicz, Delfina Bur, Ted Lain","doi":"10.1002/der2.219","DOIUrl":"10.1002/der2.219","url":null,"abstract":"<p>The present state of skincare addresses the consequences of photodamage, hormonal influences, and the cumulative impact of exposome exposure throughout a person's life. Treatments within the aesthetic domain either harness biological pathways to achieve rejuvenation, such as retinoids and antioxidants, or suppress them, like lightening ingredients. Emerging advancements encompass techniques that stimulate the differentiation of stem cells to generate younger keratinocytes and fibroblasts, activate macrophages to diminish proinflammatory cellular waste, and restore glycosaminoglycans within the dermal matrix. While these innovations have significantly enhanced the potential of skincare to revitalize the skin in recent years, obstacles to their adoption remain substantial, including complex multistep regimens, the elevated cost of novel technologies, and limited accessibility for a majority of consumers. The next phase of skincare innovation targets the root cause of aging, at the genetic and epigenetic level. By reversing the effect of the exposome at this level, it is conceivable that biological age and chronological age might no longer correlate. Additionally, the integration of artificial intelligence, the identification of biomarkers, and improved accessibility to genetic predisposition lab testing will combine to allow for greater personalization of skincare recommendations.</p>","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"4 6","pages":"284-289"},"PeriodicalIF":0.0,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/der2.219","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139264587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caitlin Egli, Mildred Min, Nasima Afzal, Raja K. Sivamani
{"title":"The hydroxy acids: Where have we been and what's new?","authors":"Caitlin Egli, Mildred Min, Nasima Afzal, Raja K. Sivamani","doi":"10.1002/der2.217","DOIUrl":"10.1002/der2.217","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Hydroxy Acids (HAs) have been used for the treatment of a variety of skin conditions over the past several decades. The use of HAs in both pharmaceutical and cosmetic products has increased dramatically, and recent studies have been undertaken to better understand their applications and therapeutic benefits.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The objective of this review is to study the uses of HAs and the emerging ingredients in the area of skin care. Relevant studies were reviewed and categorized by their molecular structure into alpha HAs (AHAs) beta HAs (BHAs) and poly HAs (PHAs).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A literature search on the use of HAs was performed and articles for review were selected from more recent dermatological studies published from 2018 to 2023. Older research was compared to the results of newer studies to identify the more recent developments in the application of HAs in skin care.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The new research was concentrated in the area of new uses of the HAs, validating therapeutic concentrations and protocols, and combining different HAs and other chemicals to improve therapeutic outcomes for a variety of skin conditions and diseases.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The articles included for review demonstrate the continuing therapeutic relevance and developments in the application of HAs in skin care.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"4 6","pages":"260-267"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/der2.217","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135243033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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