Edgar Mandeng Ma Linwa, Charlotte Eposse Ekoube, Odette Berline Sigha, Ritha Mbono Betoko, Vanessa Ghislaine Mangon A. Nnyoung, Sandra Ayuk Tatah, Nelson Venceslas Njedock Sontsa, Rose Kotto Ekambi, Anne-Cécile Bissek Zoung-Kanyi
{"title":"Assessing the Impact of Atopic Dermatitis on the Quality of Life of Paediatric Patients in Sub-Saharan Africa: A Scoping Review","authors":"Edgar Mandeng Ma Linwa, Charlotte Eposse Ekoube, Odette Berline Sigha, Ritha Mbono Betoko, Vanessa Ghislaine Mangon A. Nnyoung, Sandra Ayuk Tatah, Nelson Venceslas Njedock Sontsa, Rose Kotto Ekambi, Anne-Cécile Bissek Zoung-Kanyi","doi":"10.1002/der2.70048","DOIUrl":"https://doi.org/10.1002/der2.70048","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Atopic dermatitis (AD) significantly impairs quality of life (QoL) in children but evidence from Sub-Saharan Africa (SSA), with unique health care challenges and cultural context, is sparse. A scoping review is necessary to identify research gaps and guide policy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Following PRISMA-ScR guidelines, we reviewed studies from 2010 to 2025 on children (0–18 years) with AD in SSA, searching MEDLINE, Embase, APA PsycINFO, ProQuest, Google Scholar, African Journals Online, and regional reports. Included studies assessed design, sociodemographic factors, AD severity, and QoL outcomes. A biopsychological model and narrative synthesis were used.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Six studies (five cross-sectional, one RCT) from Cameroon, Côte d'Ivoire, Nigeria, South Africa, and Madagascar involved 53–381 urban hospital-based participants. These highlight SSA-specific challenges, including high non-mild AD prevalence (up to 61.3% moderate, 24.2% severe) versus global trends (<15% severe), driven by socioeconomic constraints and cultural stigma. Moderate to severe QoL impairment was linked to pruritus, sleep disruption, and emotional distress, correlating with disease severity (SCORAD) and younger age ( < 1 year). MMAT appraisal showed urban sampling bias, unclear Nonresponse bias, variable diagnostic criteria, and globally validated but locally unvalidated QoL tools, limiting generalisability and cultural relevance. Socioeconomic status and comorbidities (e.g., asthma) were underreported but likely exacerbate QoL burden.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>AD significantly impacts pediatric QoL in SSA, intensified by poverty and stigma. The limited representation of five countries underscores the urgent need for rural, community-based studies using validated, context-specific QoL tools to capture SSA's diverse populations and inform equitable dermatological care and policy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/der2.70048","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144869949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Threads in Aesthetic Medicine: A Review","authors":"Raheleh Sarbaziha, David J. Goldberg","doi":"10.1002/der2.70047","DOIUrl":"https://doi.org/10.1002/der2.70047","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Threads have been an integral part of aesthetic medicine for years, offering a minimally invasive solution to lift, tighten, and rejuvenate the skin. Their popularity continues to grow as technology advances, providing more options for patients seeking natural, yet noticeable, results.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This review will begin by exploring the fundamentals of threads: what they are, how they work, and why they have become a valuable tool in aesthetic medicine. We will examine the different types of threads available in the market, comparing their unique features, materials, and mechanisms of action.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>FDA-cleared indications for threads will be discussed, highlighting their safety, efficacy, and the procedural nuances that contribute to optimal outcomes. A discussion on the various types of threads will focus on their specific applications and benefits for both patients and practitioners.</p>\u0000 \u0000 <p>Several photographic examples from clinical patients who provided consent to do so will be provided. Since this was not a study but rather a review of the literature no approval was needed by a local ethics board.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This review will also explore the future of threads in aesthetic medicine, from innovations in thread technology to expanding indications and techniques.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/der2.70047","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144672976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ghada Farouk Mohammed, Mohammed Saleh Al-Dhubaibi, Lina Mohammed Atef, Saleh Salem Bahaj, Ahmed Mohammed Al-Dhubaibi
{"title":"The Relationship Between Dermatology and Visual Arts","authors":"Ghada Farouk Mohammed, Mohammed Saleh Al-Dhubaibi, Lina Mohammed Atef, Saleh Salem Bahaj, Ahmed Mohammed Al-Dhubaibi","doi":"10.1002/der2.70046","DOIUrl":"https://doi.org/10.1002/der2.70046","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Dermatology and visual arts, though seemingly distinct, share a foundational reliance on acute visual perception.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study explores the multifaceted relationships between dermatology and visual arts by examining their historical connections, mutual influences in visual literacy and diagnostics, and collaborative potentials in medical education and public health awareness. It aims to investigate how artistic training can enhance dermatological observation and how visual art reduces the stigma surrounding skin diseases.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A qualitative and interdisciplinary approach was employed, including a historical analysis of dermatologic illustrations and artworks, a thematic analysis of visual representations of skin, and a review of modern technological interventions such as AI-enhanced imaging and VR simulations. Comparisons were made between classical medical illustrations and contemporary visual depictions of skin disease in art.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study revealed a profound convergence between dermatology and visual arts in representing, interpreting, and normalizing the skin. Visual literacy drawn from art can enhance diagnostic accuracy, and artistic renderings of dermatological conditions promote empathy and de-stigmatization. Innovations like AI and 3D modeling are bridging medical accuracy with esthetic visualization in education and practice.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The intersection of dermatology and visual arts enriches both clinical practice and artistic discourse. Visual methodologies enhance diagnostic and educational outcomes in dermatology, while artistic interpretations of the skin humanize medical conditions and advocate inclusivity.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/der2.70046","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144672977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Science Behind the Label: Evaluating Claims in Dermatologist-Recommended Cosmetics","authors":"Cristina Wöhlke Vendruscolo, Edileia Bagatin, Gislaine Ricci Leonardi","doi":"10.1002/der2.70045","DOIUrl":"https://doi.org/10.1002/der2.70045","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Cosmetic product labels are a key communication tool between the cosmetic industry, consumers, and healthcare professionals. However, the clarity, consistency, and scientific basis of product claims remain under debate.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aimed to map and critically analyze the claims on labels of antiaging, facial care, body care, and sun protection products recommended by dermatologists, evaluating their scientific foundation and potential influence on consumer perception.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>An exploratory study was conducted based on 110 products from 13 leading cosmetic brands available in the Brazilian market. Data were collected between 2021 and 2022 from both primary and secondary packaging. Claims were categorized into five criteria: raw material origin (e.g., natural), galenic formulation, safety, efficacy, and absence of specific ingredients (e.g., alcohol, preservatives, mineral oils). Claims were examined using recognized methodologies for claim substantiation and relevant regulatory frameworks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>While many claims align with scientific methods and regulations, several terms remain vague or lack contextualization. Phrases such as “natural origin,” “safe,” or “clinically tested” were often inconsistent and presented without clear methodological references. This lack of standardization may hinder consumer interpretation and limit healthcare professionals’ ability to assess product relevance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The study underscores the need for clearer, standardized language in cosmetic claims. Transparent, scientifically grounded communication can support informed consumer decisions and enable healthcare professionals to make more evidence-based product recommendations.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/der2.70045","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144647125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Guest Editors Introduction “Radiation Therapy—Where Are Now in Dermatology With This Therapy?”","authors":"Mark S. Nestor","doi":"10.1002/der2.70044","DOIUrl":"https://doi.org/10.1002/der2.70044","url":null,"abstract":"","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/der2.70044","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144598603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiation Dermatitis: A Comparative Review of Prevention and Management","authors":"Aysham Chaudry, Robert J. Vanaria, Mark S. Nestor","doi":"10.1002/der2.70043","DOIUrl":"https://doi.org/10.1002/der2.70043","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Radiation dermatitis (RD) is a universal side effect of radiation therapy (RT), with management strategies differing depending on the type of cancer being treated. This review highlights the pathogenesis and management of RD following treatment of internal malignancies versus non-melanoma skin cancers (NMSC) treated with superficial RT (SRT).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A literature search was conducted using PubMed, in addition to the authors' clinical experience with RD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In patients receiving RT, RD is a concerning side effect during and following treatment of internal malignancies, yet a necessary factor in the treatment of NMSC. RD is characterized by barrier dysfunction, cellular necrosis, and inflammation. In RT for internal malignancies, many strategies may be employed to preserve skin barrier integrity. In contrast, for NMSC, the occurrence of RD is integral to the therapeutic outcome of SRT, thus interventions must be used selectively or postponed. In this setting, low-grade RD is expected and even needed; the goal should be to prevent the progression to more severe RD optimizing the therapeutic index. A ceramide-dominant triple-lipid barrier formulation (EC) has shown promise in both contexts in the management of RD through the restoration of the epidermal barrier.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In internal malignancies, maintaining skin integrity is critical to decrease morbidity and prevent RT interruption. When treating NMSC, a more cautious approach is favored, with RD management using breaks in RT and ultimately topical therapy deferred until after RT. Nonetheless, EC may offer a safe and effective strategy in restoring the epidermal barrier in both contexts.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/der2.70043","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144598604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdullah Almeziny, Rahaf Almutairi, Latifah Almehaideb, Renad Almutairi, Amal Altamimi, Khloud Alshehri, Atheer Almutairi, Asem Shadid, Fares Alkhayal, Yasser Alqubaisy
{"title":"Treatment of Cutaneous Warts in Immunocompromised Individuals: A Systematic Review","authors":"Abdullah Almeziny, Rahaf Almutairi, Latifah Almehaideb, Renad Almutairi, Amal Altamimi, Khloud Alshehri, Atheer Almutairi, Asem Shadid, Fares Alkhayal, Yasser Alqubaisy","doi":"10.1002/der2.70039","DOIUrl":"https://doi.org/10.1002/der2.70039","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>While existing literature focuses on treating warts in immunocompetent persons, there is a lack of comprehensive recommendations for managing cutaneous warts in immunocompromised (ID) patients. The review aimed to appraise the most effective and safe treatment for cutaneous warts in ID patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>The systematic review followed (PRISMA) guidelines. The PubMed, Scopus, and Cochrane databases were employed to search for papers published between January 2015 and May 2024.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Two hundred twenty-five studies were found, however this study included 16 studies. Among the reviewed studies, there was one RCT, 11 case reports, and four case series/retrospective cohort studies. Despite the precise pathway of action of various antigens is undetermined, immunotherapies offer a secure and economically feasible method of treating warts. Other frequently employed therapies include cryotherapy and salicylic acid and are generally effective for the management of warts at the area of interest. The majority of the studies analyzed had low RoB when assessed using the ROBINS-E approach.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This review summarised the available literature on the application of immunotherapies for managing resistant warts. It revealed that immunotherapy is a viable treatment for ID people who have not responded to previous medications.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/der2.70039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144536920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evalicia Murúa, Luis Alberto Parra, Andreina Martinez Amado, Alejandra Bugallo, Victoria De la Fuente, Eliana Garcés, Andrea Marcela Parra
{"title":"Examining Periocular Aging: A Narrative Review of its Causes and Aesthetic Interventions","authors":"Evalicia Murúa, Luis Alberto Parra, Andreina Martinez Amado, Alejandra Bugallo, Victoria De la Fuente, Eliana Garcés, Andrea Marcela Parra","doi":"10.1002/der2.70041","DOIUrl":"https://doi.org/10.1002/der2.70041","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Importance</h3>\u0000 \u0000 <p>The periocular area is crucial for facial aesthetics and communication, significantly impacting perceptions of youth and vitality. Understanding its aging mechanisms and refining intervention strategies are essential for optimal outcomes. This review integrates clinical insights from multidisciplinary practice to address gaps in personalized decision-making.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Observations</h3>\u0000 \u0000 <p>Contemporary literature and clinical experience identify key periocular aging factors, including sequenced fat compartment deflation, bony resorption, and skin quality decline. Novel findings include a structured algorithm for injectable sequencing, emphasizing deep medial cheek volumization before tear trough correction to mitigate complications. Clinical pearls highlight hybrid techniques (e.g., microdroplet botulinum toxin with HA fillers) for dynamic wrinkles. While hyaluronic acid fillers remain central, case examples demonstrate synergistic outcomes when combined with surgical referrals (e.g., ptosis repair). Emerging ultrasound-guided approaches enhance precision in high-risk zones.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions and Relevance</h3>\u0000 \u0000 <p>Periocular rejuvenation demands a holistic, individualized strategy. The proposed algorithm, supported by complication management protocols and a surgery-injectables decision framework, optimizes outcomes. Clinicians must balance volume restoration with anatomical stability, leveraging multidisciplinary insights to address both aesthetic and functional decline.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"6 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/der2.70041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144264663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to “Gender and Sex Disparities in Melanoma: Advances in Diagnosis, Treatment, and the Role of Artificial Intelligence”","authors":"","doi":"10.1002/der2.70034","DOIUrl":"https://doi.org/10.1002/der2.70034","url":null,"abstract":"<p>D. R. K. Kakish, J. F. Alsamhori, L. N. Qaqish, et al. “Gender Disparities in Melanoma: Advances in Diagnosis, Treatment, and the Role of Artificial Intelligence,” <i>Dermatologic Therapy</i> 2025; e70022, https://doi.org/10.1002/der2.70022.</p><p>In the title of the published article, the phrase “Gender Disparities in Melanoma” should read “Gender and Sex Disparities in Melanoma” to more accurately reflect the scope of the manuscript, which discusses disparities related to both gender identity and biological sex in melanoma diagnosis, treatment, and research.</p><p>We apologize for this error.</p>","PeriodicalId":100366,"journal":{"name":"Dermatological Reviews","volume":"6 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/der2.70034","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144171234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}