Chem & Bio Engineering最新文献_第3页

Preface for a Special Issue on Sustainable Catalysis 关于可持续催化的特刊序言。

IF 8.4

Chem & Bio Engineering Pub Date : 2026-07-23 DOI: 10.1021/cbe.6c00076

Feng-Shou Xiao

引用次数: 0

Development of an Experimental Setup and a Validated Model for a Highly Integrated Biocatalytic Process 高度集成生物催化过程的实验装置和验证模型的开发。

IF 8.4

Chem & Bio Engineering Pub Date : 2026-07-23 Epub Date: 2026-03-26 DOI: 10.1021/cbe.5c00167

Francesca von Ziegner, Grit Brauckmann, Christoph Witthoefft, Paul Bubenheim, Thomas Waluga

引用次数: 0

All-Dry Molecular Scale Processing for Shaping Open Pockets with CO2 Affinity in a Covalent Organic Framework 在共价有机骨架中形成具有CO2亲和力的开放口袋的全干分子尺度加工。

IF 8.4

Chem & Bio Engineering Pub Date : 2026-07-23 Epub Date: 2026-04-29 DOI: 10.1021/cbe.6c00035

Zhiwen Chen, Yicheng Luo, Jipeng Xu, Ming Zhang, Chunxiao Li, Rundao Chen, Yingwu Luo, Zongbi Bao, Cheng Lian, Junjie Zhao

{"title":"All-Dry Molecular Scale Processing for Shaping Open Pockets with CO2 Affinity in a Covalent Organic Framework","authors":"Zhiwen Chen, Yicheng Luo, Jipeng Xu, Ming Zhang, Chunxiao Li, Rundao Chen, Yingwu Luo, Zongbi Bao, Cheng Lian, Junjie Zhao","doi":"10.1021/cbe.6c00035","DOIUrl":"10.1021/cbe.6c00035","url":null,"abstract":"Carbon dioxide capture is key toachieving carbon neutralityandaddressing climate change. Covalent organic frameworks (COFs) withtailored pore structures have emerged as potential candidates forCO2 adsorption. However, previous postsynthetic modificationmethods often face an inevitable trade-off between increasing adsorptionsites and maintaining pore accessibility. Herein, we report an all-drymolecular scale processing (MSP) approach that forms open pocketsin COF mesopores by covalently grafting chains with Zn open metalsites and primary amine groups as dual CO2-philic sites.The resulting COF not only maintains a BET surface area up to 1180m2 g–1 but also enables an ideal selectivityfor CO2/N2 of 153 at 100 kPa, which is almost10-fold higher than the pristine COF. Mechanistic investigations revealthat micropore filling and strong binding sites contribute to enhancedCO2 adsorption. The pore engineering strategy reportedhere provides essential insights for developing the next generationof adsorbent materials.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 7","pages":"650–655"},"PeriodicalIF":8.4,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148611622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Bioelectrode Healing via Engineered Electrode Reconstruction on Biofilms under Strong Acid and Ultrahigh Current Density 强酸和超高电流密度下生物膜工程电极重建的生物电极愈合。

IF 8.4

Chem & Bio Engineering Pub Date : 2026-06-25 Epub Date: 2026-02-23 DOI: 10.1021/cbe.5c00150

Jingkai Zhao, Manli Rao, Yao Shen, Qiaoli Wang, Jiexu Ye, Ke Feng, Shihan Zhang

{"title":"Bioelectrode Healing via Engineered Electrode Reconstruction on Biofilms under Strong Acid and Ultrahigh Current Density","authors":"Jingkai Zhao, Manli Rao, Yao Shen, Qiaoli Wang, Jiexu Ye, Ke Feng, Shihan Zhang","doi":"10.1021/cbe.5c00150","DOIUrl":"10.1021/cbe.5c00150","url":null,"abstract":"Novelbioelectrodes are being developed to advance theapplicationsof bioelectrocatalytic technology in various energy and environmentalscenarios. However, concerns about the sustainability of engineeredelectrodes during prolonged operation is keeping raised. This studyproposes a novel bioelectrode healing strategy via in situ electrodereconstruction on biofilms. The amount of viable cells in healed bioelectrodedecreases by 24.23% because of the extreme conditions of strong acid(pH 0.1) and ultrahigh current density (−4.4 to 8.5 ×105 mA m–2) during the redeposition ofsponge-like polyaniline@carbon nanotube; however, it quickly recoversto 1.88-fold that of the unhealed bioelectrode. Compared with thecontrol, the healed bioelectrode attains a 2.61-fold toluene degradationkinetics (2.71 h–1), a 1.36-fold power density (401.4mW m–2), and a 1.09-fold Coulombic efficiency (14.69%),which are also considerably higher than the literature results. Theenergy cost for electrode healing (19.05 J) accounted for ∼4.7%of the energy recovered in the following operation, thus confirmingthe energy efficiency of the healing strategy. In addition, the outputvoltage of the healed bioelectrode decreases by 17.1% at the end ofa 60-day operation, with the corresponding decrement being 41.0% forthe unhealed control. Furthermore, the elevated concentrations ofATP, NADH, and c-type cytochromes, along with the upregulated genesrelated to intracellular and extracellular electron transfer, arefound to be the driving forces behind the superior and durable performance.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 6","pages":"585–597"},"PeriodicalIF":8.4,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148355308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Strategies for Mitigation of Intermediate CO2 Poisoning to Promote Electrocatalytic Efficiency during Urea Oxidation Reaction 缓解尿素氧化反应中中间CO2中毒以提高电催化效率的策略

IF 8.4

Chem & Bio Engineering Pub Date : 2026-06-25 Epub Date: 2026-03-02 DOI: 10.1021/cbe.5c00161

Sannibha Das, Prachi Upadhyay, Akash Joshy, Sankar Chakma

{"title":"Strategies for Mitigation of Intermediate CO2 Poisoning to Promote Electrocatalytic Efficiency during Urea Oxidation Reaction","authors":"Sannibha Das, Prachi Upadhyay, Akash Joshy, Sankar Chakma","doi":"10.1021/cbe.5c00161","DOIUrl":"10.1021/cbe.5c00161","url":null,"abstract":"Urea electrolysis plays a key role in various urea wastevalorizationprocesses. In this regard, the complex six-electron transfer process,urea oxidation reaction, is the key to achieving maximum efficiency.In this study, we developed multilayered α-Ni(OH)2 sheets through a sonochemical approach. We used Fe3+ todope the α-Ni(OH)2 sheets in three different compositions.The synthesized catalysts were analyzed by using XRD, SEM, EDX, FTIR,and XPS. Using EDX and XPS, successful doping of iron was confirmed.The electrocatalytic activities were characterized by CV, LSV, EIS,and CA techniques. Through CV analysis, it was identified that Fe3+ did not directly participate in the electrochemical reaction;rather, due to high Lewis acidity, it was modulating the electronicenvironment of Ni2+ ions. Iron doping induced a reductionin the onset potential and synergistically increased the catalyticcurrent by promoting a higher number of active sites for urea adsorption.Tafel analysis concluded that the improved reaction kinetics was dueto iron incorporation. Using Nyquist and Bode plots, it was identifiedthat iron doping promoted CO2 production as RDS. Therefore,catalyst poisoning due to prolonged adsorption of CO2 wasdiminished, and subsequently, catalyst stability was increased. Overall,while Fe3+ doping has proved to be a significant methodto enhance catalytic activity, careful optimization of concentrationis required to build a state-of-the-art catalytic architecture forurea waste valorization.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 6","pages":"598–609"},"PeriodicalIF":8.4,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148355414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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New Frontiers in AI-Nano Converged Platforms for Intelligent Diagnostics, Therapeutics, and Safety Evaluation 智能诊断、治疗和安全评估的ai -纳米融合平台的新领域。

IF 8.4

Chem & Bio Engineering Pub Date : 2026-06-25 Epub Date: 2026-03-28 DOI: 10.1021/cbe.5c00188

Huijie Zhou, Jiming Xu, Xinyu Qin, Jing Zhang, Wenjiang Zou, Mohsen Shakouri, Jun Wu, Lvzhou Li, Yuping Li, Jianning Ding, Huan Pang

{"title":"New Frontiers in AI-Nano Converged Platforms for Intelligent Diagnostics, Therapeutics, and Safety Evaluation","authors":"Huijie Zhou, Jiming Xu, Xinyu Qin, Jing Zhang, Wenjiang Zou, Mohsen Shakouri, Jun Wu, Lvzhou Li, Yuping Li, Jianning Ding, Huan Pang","doi":"10.1021/cbe.5c00188","DOIUrl":"10.1021/cbe.5c00188","url":null,"abstract":"The complexity of nanomedicine poses a significant challengetotraditional empirical methods. Machine learning (ML), with its abilityto parse high-dimensional data and predict nonlinear interactions,is empowering AI nano fusion platforms, driving innovation in diagnosticand therapeutic evaluation paradigms. This review explores breakthroughapplications of ML in core areas of nanomedicine, including intelligentdiagnosis (such as ML enhanced nanosensors for high-precision noninvasivecancer early screening), precision therapy (such as closed-loop systemdriven rational design and delivery optimization of nanomedicine),safety assessment (such as interpretable AI prediction of biologicaland environmental toxicity of nanomaterials), and clinical translation(to address scientific challenges related to standardization, reproducibility,and regulatory). The paper provides an in-depth analysis of the keybottlenecks currently facing the transition from laboratory to clinicalapplication, such as batch differences, dynamic interference, andregulatory lag. Based on recent research progress, a future pathto achieve an intelligent closed-loop of “design diagnosisand treatment evaluation” is proposed, providing key insightsfor the development of the next generation of safe and efficient intelligentnanodiagnosis and treatment platforms.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 6","pages":"555–584"},"PeriodicalIF":8.4,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148355305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrarapid Purification of Manganese-52 from Chromium-52 Targets via Potentiostatic Anodic Dissolution and Chelation Ion Chromatography 恒电位阳极溶解和螯合离子色谱法从铬-52靶中超快速纯化锰-52。

IF 8.4

Chem & Bio Engineering Pub Date : 2026-06-25 Epub Date: 2026-03-04 DOI: 10.1021/cbe.5c00131

Qi Zhao, Junyi Wang, Junhua Xu, Mengxian Liu, Kaimin Shih

{"title":"Ultrarapid Purification of Manganese-52 from Chromium-52 Targets via Potentiostatic Anodic Dissolution and Chelation Ion Chromatography","authors":"Qi Zhao, Junyi Wang, Junhua Xu, Mengxian Liu, Kaimin Shih","doi":"10.1021/cbe.5c00131","DOIUrl":"10.1021/cbe.5c00131","url":null,"abstract":"Manganese-52 (52 Mn, t1/2 = 5.6 days) is an attractive positron-emitting isotopefor integratedpositron emission tomography and magnetic resonance imaging. Its availability,however, is constrained by the challenge of achieving rapid, high-purityseparation from cyclotron-irradiated chromium-52 (52Cr)targets. This study presents an ultrarapid, two-step purificationstrategy that couples potentiostatic anodic dissolution with single-columnchelation ion chromatography. Electrochemical analysis indicates thatthe Mn target undergoes rapid oxidation and is dissolved as amminecomplexes in an ammonium/ammonium chloride buffer (pH 8) at 0.7 V(vs Hg/HgO), whereas the Cr target remained almost passivated andtrace Cr leached was precipitated on the target surface as Cr(OH)3 under identical conditions. The sharp decrease in anodiccurrent density, induced by the distinct dissolution behavior of Mn/Crtargets, provides a convenient real-time endpoint for assessing completeMn dissolution. The resulting analyte was then loaded directly ontoiminodiacetate resins (Diaion CR11) and eluted with HCl, convertingthe ammine complexes to hydrated Mn2+. Simulated experimentsachieved a Mn chromatographic recovery of 98.65% with >99.99% puritywithin 30 min. This integrated approach offers significant advantagesin processing speed and recovery yield over conventional methods,demonstrating high potential for the production of clinical 52 Mn.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 6","pages":"610–618"},"PeriodicalIF":8.4,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148355421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanoengineered All-Cellulose Bilayer Barrier Papers for High-Performance and Recyclable Food Packaging 用于高性能和可回收食品包装的纳米工程全纤维素双层阻隔纸。

IF 8.4

Chem & Bio Engineering Pub Date : 2026-06-25 Epub Date: 2026-04-29 DOI: 10.1021/cbe.6c00054

Roufen Wu, Jiahe Li, Ze Ji, Xiao Han, Da Zhang, Khak Ho Lim, Zhenglong Li, Tiffany Abitbol, Wen-Jun Wang, Xuan Yang

{"title":"Nanoengineered All-Cellulose Bilayer Barrier Papers for High-Performance and Recyclable Food Packaging","authors":"Roufen Wu, Jiahe Li, Ze Ji, Xiao Han, Da Zhang, Khak Ho Lim, Zhenglong Li, Tiffany Abitbol, Wen-Jun Wang, Xuan Yang","doi":"10.1021/cbe.6c00054","DOIUrl":"10.1021/cbe.6c00054","url":null,"abstract":"Plastic packaging poses a major environmentalchallenge, yet mostpaper-based alternatives rely on unsustainable coatings and additivesto achieve barrier and mechanical performance. Here, we introducean all-cellulose bilayer barrier paper in which cellulose nanofibrils(CNFs) function as a dual-purpose coating and reinforcement. Ratherthan applying CNFs as a postcoating, we employ a simple filtrationprocess combining pulp fibers and CNFs that induces spontaneous bilayerformation, yielding a dense CNF layer atop a pulp-rich substrate.This design delivers outstanding performance: oil resistance exceedscommercial standards even at 85 °C (KIT Level 12), water contactangle increases by >60°, water absorption is significantlyreduced(Cobb60 decreases from 290 to 50 g·m–2), and thermal stability can hold up to 270 °C. While air permeabilitydecreases to near zero, the material maintains a moderate oxygen transmissionrate at 50% relative humidity (97 cc·m–2·day–1·atm–1). Beyond a 200% improvementin mechanical strength and wet strength suitable for food packagingapplications, the bilayer structure remains robust under folding andpeeling, outperforming commercial papers for hot food, refrigeratedmeats, and baking. Importantly, the all-cellulose composition enablesover 98% fiber recovery by recycling, substantially reducing the carbonfootprint relative to commercial food barrier papers with limitedrecyclability. By combining nanoengineering, high functionality, andcircularity, this work establishes a biobased platform for sustainablefood packaging with broad societal and environmental impact.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 6","pages":"619–632"},"PeriodicalIF":8.4,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148355288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mg2+-Dependent Remodeling of Biomolecular Condensates’ Microenvironments for Tunable Molecular Uptake and Altered Biochemical Dynamics Mg2+依赖性的生物分子凝聚物微环境重塑，可调节分子摄取和改变生化动力学。

IF 8.4

Chem & Bio Engineering Pub Date : 2026-05-28 Epub Date: 2026-04-27 DOI: 10.1021/cbe.6c00002

Yifeng Zhu, Xinran Yu, Chengying Yin, Xingxin Liu, Zhengyan Wu, Delong Zhang, Hyeon Jeong Lee, Liangfei Tian

{"title":"Mg2+-Dependent Remodeling of Biomolecular Condensates’ Microenvironments for Tunable Molecular Uptake and Altered Biochemical Dynamics","authors":"Yifeng Zhu, Xinran Yu, Chengying Yin, Xingxin Liu, Zhengyan Wu, Delong Zhang, Hyeon Jeong Lee, Liangfei Tian","doi":"10.1021/cbe.6c00002","DOIUrl":"10.1021/cbe.6c00002","url":null,"abstract":"Biomolecular condensates have emergedas a transformativeparadigmin biomedical and materials sciences due to their unique capacityfor molecular sequestration and dynamic adaptability. Precise modulationof their microenvironmental properties enables versatile applicationsincluding protocell engineering, targeted therapeutics, and smartbioreactor systems. Here, we demonstrate that multivalent ions, exemplifiedby magnesium ions (Mg2+), exert concentration-dependentregulation of condensate physicochemical properties and biologicalfunctions. Using a model system composed of cationic arginine decamer(R10) and anionic polyglutamate (PolyE), we systematically show thatMg2+ concentration gradients influence the size distribution,surface charge, viscosity, and internal polarity. Critically, we establishlinks between ion-induced microenvironmental changes and functionaloutcomes: (i) dsDNA structural stability and ssDNA hybridization kineticsare altered in an ion-dependent manner; (ii) guest molecule enrichmentcapacity shows selective tuning; and (iii) alkaline phosphatase (ALP)catalytic efficiency exhibits nonlinear dose–response relationships.These findings offer mechanistic insights into cellular ion homeostasisand provide design principles for ion-responsive synthetic condensateswith programmable functionality. Our work bridges fundamental biophysicalprinciples with translational applications in smart biomaterials andprecision medicine.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 5","pages":"535–545"},"PeriodicalIF":8.4,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148152775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancement Strategies for Bioelectrocatalytic Conversion of Organic Waste 有机废物生物电催化转化的改进策略。

IF 8.4

Chem & Bio Engineering Pub Date : 2026-05-28 Epub Date: 2026-03-24 DOI: 10.1021/cbe.5c00179

Ye Wang, Yinuo Xie, Rong Dong, Yuanpeng Wang

{"title":"Enhancement Strategies for Bioelectrocatalytic Conversion of Organic Waste","authors":"Ye Wang, Yinuo Xie, Rong Dong, Yuanpeng Wang","doi":"10.1021/cbe.5c00179","DOIUrl":"10.1021/cbe.5c00179","url":null,"abstract":"Bioelectrocatalytic conversion of organic waste usesrenewableelectricity to convert organic waste into high-value chemicals andfuels under mild conditions. It is regarded as a strategic link connectingwaste refinement and the green economy, providing a sustainable approachfor the high-value utilization of waste resources. This article systematicallyreviews: (1) the basic principles and reaction mechanisms of bioelectrocatalyticconversion of organic waste; (2) the development history and key breakthroughsof organic waste biological electrochemical conversion; (3) microbialengineering strategies based on genetic engineering and syntheticbiology; (4) the directions for process and reactor optimization.This review uniquely integrates advancements in biological innovationand process engineering, offering a holistic perspective on synergisticoptimization across molecular, microbial, and reactor scales. By explicitlybridging microbial carbon/electron flux engineering with bioreactordesign and process coupling, it aims to establish a comprehensiveroadmap for accelerating the industrial-scale application of bioelectrocatalytictechnologies in organic waste treatment.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 5","pages":"496–512"},"PeriodicalIF":8.4,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148152846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0