Chem & Bio Engineering最新文献

Transforming Photovoltaic Waste into High-Performance Battery Materials through a Closed-Loop Upcycling Strategy 通过闭环升级回收策略将光伏废弃物转化为高性能电池材料

IF 8.4

Chem & Bio Engineering Pub Date : 2026-10-22 Epub Date: 2026-06-11 DOI: 10.1021/cbe.6c00036

Menghan Wu, Xiaoyu Zhang, Xiaojie Fang, Asad Ali Shah Zaidi, Yao Nian, You Han

{"title":"Transforming Photovoltaic Waste into High-Performance Battery Materials through a Closed-Loop Upcycling Strategy","authors":"Menghan Wu, Xiaoyu Zhang, Xiaojie Fang, Asad Ali Shah Zaidi, Yao Nian, You Han","doi":"10.1021/cbe.6c00036","DOIUrl":"https://doi.org/10.1021/cbe.6c00036","url":null,"abstract":"With the explosive growth of globalphotovoltaic (PV) installedcapacity, a massive wave of PV module decommissioning is imminent.Retired modules contain valuable resources, including high-puritysilicon, silver, and aluminum. Improper disposal may not only leadto resource loss but also pose risks of ecotoxicity. The efficientconversion of PV waste into battery materials aligns with environmentalprotection requirements and represents a critical pathway to securethe strategic supply of high-performance silicon-based anode materials.However, current research predominantly focuses on isolated technologicalsteps and lacks a systematic synthesis of the entire value chain.This paper provides a comprehensive overview of the full-chain technologicalpathways for the value-added utilization of PV waste in the batterysector. It offers a multidimensional analysis of the resource value,the spatiotemporal evolution of the decommissioning wave, and theassociated environmental risks of PV waste. Focusing on the criticalbottlenecks in the preprocessing stage for battery-grade conversion,we dissect the key technologies for silicon waste purification. Tracingthe regeneration pathways for battery materials, we summarize strategiesfor structural design and functional modification of waste-derivedsilicon, and elucidate the mechanisms for mitigating volume expansionin silicon anodes. A realistic assessment of current industrial challengesis provided, alongside an outlook on the prospects for value-addedutilization. By delineating the technological roadmap and transformationlogic from PV waste to battery material recycling, we aim to contributeto the construction of a closed-loop green industry for “energygeneration-storage”.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 10","pages":"819–841"},"PeriodicalIF":8.4,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemo-Enzymatic Synthesis of Purine 3′-O-Amino-Deoxyribonucleoside Triphosphates 嘌呤3′- o-氨基脱氧核糖核苷三磷酸的化学酶法合成

IF 8.4

Chem & Bio Engineering Pub Date : 2026-10-22 Epub Date: 2026-08-09 DOI: 10.1021/cbe.6c00032

Qin He, Shuai Cheng, Jianqing Yue, Shu Zong, Congyu Li, Xuerong Qi, Lipei Liu, Zhidan Zhang, Jun Sun, Jian Cheng, Xiaoyun Lu, Huifeng Jiang

{"title":"Chemo-Enzymatic Synthesis of Purine 3′-O-Amino-Deoxyribonucleoside Triphosphates","authors":"Qin He, Shuai Cheng, Jianqing Yue, Shu Zong, Congyu Li, Xuerong Qi, Lipei Liu, Zhidan Zhang, Jun Sun, Jian Cheng, Xiaoyun Lu, Huifeng Jiang","doi":"10.1021/cbe.6c00032","DOIUrl":"https://doi.org/10.1021/cbe.6c00032","url":null,"abstract":"3′-O-amino-deoxyribonucleosidetriphosphates (3′-ONH2-dNTPs) are crucial reversibleterminators for template-independentDNA synthesis. Owing to the structural complexity of purine bases,here we propose a chemo-enzymatic process for the synthesis of purine-type3′-ONH2-dNTPs. First, the aminoalkoxyl group wasintroduced into commercially available dA and dG via a chemical catalyticprocess, affording yields of 24.9% and 27.3%, respectively. Subsequently,to establish a green and scalable enzymatic cascade for phosphorylationof the substrates, we engineered two key phosphorylation enzymes (Dm-dNKand MrPPK2), improving the rate-limiting monophosphorylation of 3′-ONH2-dG from 26% to 97.8% and achieving 59.9% conversion to thecorresponding triphosphate. Lastly, the produced nucleotides exhibitperformance equivalent to commercial counterparts in terminal deoxynucleotidyltransferase (TdT)-mediated DNA synthesis, supporting the constructionof 120-nt strands with ∼99.7% stepwise accuracy. This workestablishes an efficient and generalizable catalytic platform forproducing modified dNTPs, advancing the practical application of enzymaticDNA synthesis technologies.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 10","pages":"876–887"},"PeriodicalIF":8.4,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Water-Lean [DBAPA][52AMP]-Ethanol-H2O Absorbent Enables Efficient CO2 Capture with Low Regeneration Heat Duty 一种水精[DBAPA][52AMP]-乙醇-水吸收体，可实现低再生热负荷的高效CO2捕获

IF 8.4

Chem & Bio Engineering Pub Date : 2026-10-22 Epub Date: 2026-08-18 DOI: 10.1021/cbe.6c00114

Shixuan Li, Chao Liu, Ya Lu, Hengyu Li, Yang Liu, Jinqing Lin, Qinghai Long, Boyi Zhang, Zuoming Zhou, Bihong Lv, Guohua Jing

{"title":"A Water-Lean [DBAPA][52AMP]-Ethanol-H2O Absorbent Enables Efficient CO2 Capture with Low Regeneration Heat Duty","authors":"Shixuan Li, Chao Liu, Ya Lu, Hengyu Li, Yang Liu, Jinqing Lin, Qinghai Long, Boyi Zhang, Zuoming Zhou, Bihong Lv, Guohua Jing","doi":"10.1021/cbe.6c00114","DOIUrl":"https://doi.org/10.1021/cbe.6c00114","url":null,"abstract":"To address the challenges of highdesorption temperatures and excessiveregeneration energy consumption in conventional organic amine absorbents,a novel functionalized ionic liquid-based ternary water-lean absorbent,[DBAPA][52AMP]-Ethanol-H2O, was proposed for efficientCO2 capture. This novel absorbent not only demonstratedexcellent absorption performance, achieving a CO2 loadingof 1.03 mol·mol–1, but also could be regeneratedat a low temperature of 371 K, with a regeneration efficiency of 94%.The heat duty was estimated as 2.12 GJ·t–1 CO2, representing a 43.8% reduction compared to the benchmarkMEA solution. Mechanistic studies using 13C NMR revealedthat the dominant reaction during absorption–desorption isthe conversion of carbamate to ethyl carbonate in the presence ofethanol, with minimal hydrolysis due to the low water content. Thisreaction pathway facilitated easier desorption and reduced regenerationenergy consumption. The proposed reaction mechanism involves the initialformation of a zwitterion between the cation and CO2, followedby deprotonation of the cation, transferring the proton to the tertiaryamine in the anion. Deprotonation was found to be the rate-limitingstep, and its low activation energy barrier allows for efficient desorptionat low temperature. This work offers valuable insights into the developmentof ionic liquid-based water-lean absorbents for industrial carboncapture, integrating low energy consumption, high efficiency, andexcellent recyclability.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 10","pages":"900–910"},"PeriodicalIF":8.4,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound-Activated Paclitaxel Prodrug Potentiates Suppression of Tumor Growth and Metastasis 超声激活紫杉醇前药增强肿瘤生长和转移的抑制作用

IF 8.4

Chem & Bio Engineering Pub Date : 2026-10-22 Epub Date: 2026-08-01 DOI: 10.1021/cbe.6c00093

Xitong Ren, Qitian Jing, Jiali Sun, Chaoying Kong, Na Shen, Zhaohui Tang

{"title":"Ultrasound-Activated Paclitaxel Prodrug Potentiates Suppression of Tumor Growth and Metastasis","authors":"Xitong Ren, Qitian Jing, Jiali Sun, Chaoying Kong, Na Shen, Zhaohui Tang","doi":"10.1021/cbe.6c00093","DOIUrl":"https://doi.org/10.1021/cbe.6c00093","url":null,"abstract":"Paclitaxel (PTX) remains a first-linechemotherapeutic agent, yetits therapeutic index is limited by poor tumor selectivity, nonspecificbiodistribution, and systemic toxicity. Here, we report an ultrasound(US)-activated PTX prodrug nanoplatform (PTX@TBR NPs) for tumor-selectiveand spatiotemporally controlled PTX activation. PTX was covalentlymasked with a US-responsive thioketal (TK) linker and conjugated toa polymer, while riboflavin tetrabutyrate (TBR), a vitamin B2-derived sonosensitizer, was coencapsulated to enable sonochemicalactivation. Upon US irradiation, TBR generated singlet oxygen (1O2), which oxidized the TK linker and triggeredits cleavage, thereby enabling on-demand PTX release with an efficiencyof up to 68.0%. In vivo, PTX@TBR NPs+US achievedpotent tumor inhibition, with a tumor suppression rate of 80.1%. Unexpectedly,this treatment also markedly suppressed distant metastasis. Transcriptomicanalysis revealed broad downregulation of genes associated with redox-relatedmetabolism, extracellular matrix remodeling, and lipid metabolic pathways,suggesting that sonochemical activation and PTX release cooperativelydisrupted redox homeostasis, cytoskeletal functions, and metabolicadaptation. This study establishes a sonochemically amplified prodrugactivation strategy for selective PTX chemotherapy and the inhibitionof tumor growth and metastasis.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 10","pages":"888–899"},"PeriodicalIF":8.4,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Data-Efficient Distal Engineering of Fluorinase Using Zero-Shot Models 基于零射击模型的数据高效氟化酶远端工程

IF 8.4

Chem & Bio Engineering Pub Date : 2026-10-22 Epub Date: 2026-08-05 DOI: 10.1021/cbe.6c00028

David Harding-Larsen, Brianna M. Lax, Christopher Kurt Weingarten, Aboubakar Sako, Stanislav Mazurenko, Ditte Hededam Welner

引用次数: 0

Piezocatalytic Therapy for Periodontitis: From Biofilm Disruption to Immunomodulatory Tissue Regeneration 牙周炎的压电催化治疗：从生物膜破坏到免疫调节组织再生

IF 8.4

Chem & Bio Engineering Pub Date : 2026-10-22 Epub Date: 2026-07-18 DOI: 10.1021/cbe.6c00056

Shiqi Tian, Zihao Wang, Dawei Gao, Anshuo Li

{"title":"Piezocatalytic Therapy for Periodontitis: From Biofilm Disruption to Immunomodulatory Tissue Regeneration","authors":"Shiqi Tian, Zihao Wang, Dawei Gao, Anshuo Li","doi":"10.1021/cbe.6c00056","DOIUrl":"https://doi.org/10.1021/cbe.6c00056","url":null,"abstract":"Periodontitis is a chronic inflammatorydisease characterized byan interplay between microbial dysbiosis and dysregulated host immuneresponses. Traditional therapies, including scaling and root planingcombined with localized antimicrobial administration, often strugglewith the drug resistance of structured biofilms and persistent inflammation.Piezocatalysis is an emerging on-demand intervention that, in situ, transforms mechanical energy from both endogenousand exogenous sources into therapeutic reactive oxygen species (ROS)and bioelectric signals. Unlike conventional antibiotics, these locallygenerated ROS can degrade the biofilm matrix to eradicate resistantpathogens, while the concurrent bioelectric cues resolve persistentinflammation, offering a promising solution for periodontitis treatment.This review delineates the evolution of piezoelectric biomaterialsand analyzes activation strategies tailored for the oral microenvironment.Key clinical translation bottlenecks, including the protein coronaeffect and biofilm penetration barriers, are critically addressed.Furthermore, synergistic methods that integrate nanocatalytic therapyand immune engineering strategies are highlighted to modulate theperiodontal immune microenvironment. By leveraging stimuli-responsiveelements and biomimetic materials, piezocatalytic platforms are evolvingfrom passive bactericidal agents into bioactive modulators capableof simultaneously eradicating pathogens and guiding tissue healing.This shift marks a transition from disease control toward the precisereconstruction of periodontal homeostasis and functional tissue regeneration.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 10","pages":"842–864"},"PeriodicalIF":8.4,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Continuous Production of Mesoporous Silica with Controlled Structure via Aerosol-Assisted Evaporation-Induced Self-Assembly 通过气溶胶辅助蒸发诱导自组装连续生产结构可控的介孔二氧化硅

IF 8.4

Chem & Bio Engineering Pub Date : 2026-09-24 Epub Date: 2026-06-22 DOI: 10.1021/cbe.6c00038

Ibrahim A. Alnutaifi, Nidhi Kapil, Marc-Olivier Coppens

{"title":"Continuous Production of Mesoporous Silica with Controlled Structure via Aerosol-Assisted Evaporation-Induced Self-Assembly","authors":"Ibrahim A. Alnutaifi, Nidhi Kapil, Marc-Olivier Coppens","doi":"10.1021/cbe.6c00038","DOIUrl":"https://doi.org/10.1021/cbe.6c00038","url":null,"abstract":"This work demonstrates a viable and attractive continuoussynthesisroute for spherical SBA-15 mesoporous silica particles using the aerosol-assistedevaporation-induced self-assembly (AA-EISA) technique. This approachintegrates aerosol processing with a self-assembly mechanism drivenby solvent evaporation, offering distinct advantages over conventionalsol–gel and hydrothermal methods. The influence of ethanolcontent, pH, P123 template amount, and reactor temperature (Tr) on the formation of SBA-15 spheres was systematicallyinvestigated using gas physisorption, thermogravimetric analysis (TGA),small-angle X-ray scattering (SAXS), and electron microscopy. In theabsence of ethanol, the desired spherical morphology was not obtained;instead, the products consisted of mixed, fiber-like elongated featuresand bundled aggregates, highlighting ethanol’s pivotal rolein directing spherical particle formation. An ethanol/tetraethyl orthosilicate(TEOS) molar ratio of 1 was sufficient to maintain a spherical morphologyduring continuous runs up to 12 h. For production extending beyond12 h, a ratio of 3 was required to ensure precursor stability andto balance surface area with pore volume. Adjusting the pH to 3 enabledpore expansion to ∼20 nm and a pore volume of 1 cm3/g, with a moderate surface area of 194 m2/g. Lower ethanoland acid usage suggest a more sustainable process. A P123/TEOS molarratio of 0.015 was sufficient to yield well-ordered mesostructureswith minimal reactor fouling. Reducing Tr from 400 to 200 °C decreased energy consumption without sacrificingquality, however, a further reduction to 120 °C compromised themorphology. Key parameters affecting continuous AA-EISA productionare given, showing potential for a robust, energy-efficient, and environmentallyconscious route to produce mesoporous silica particles.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 9","pages":"793–808"},"PeriodicalIF":8.4,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149022797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suppressing Ethylene Peroxidation via Introduction of Trace Amount of K+: A Strategy for Low-Cost and Highly Efficient MoVNbTeOx in Oxidative Dehydrogenation of Ethane 引入微量K+抑制乙烯过氧化反应：乙烷氧化脱氢低成本高效的MoVNbTeOx策略

IF 8.4

Chem & Bio Engineering Pub Date : 2026-09-24 Epub Date: 2026-06-23 DOI: 10.1021/cbe.6c00043

Changyan Xu, Yaoxing Lin, Yuxin Chen, Shuairen Qian, Yi Cheng

{"title":"Suppressing Ethylene Peroxidation via Introduction of Trace Amount of K+: A Strategy for Low-Cost and Highly Efficient MoVNbTeOx in Oxidative Dehydrogenation of Ethane","authors":"Changyan Xu, Yaoxing Lin, Yuxin Chen, Shuairen Qian, Yi Cheng","doi":"10.1021/cbe.6c00043","DOIUrl":"https://doi.org/10.1021/cbe.6c00043","url":null,"abstract":"MoVNbTeOx, one of the mostpromisingcatalysts for the oxidative dehydrogenation of ethane (ODHE) process,is conventionally synthesized from metal salt solutions, which limitsits application due to the high cost of precursors. In this work,we first improved the synthetic pathway of MoVNbTeOx by using metal oxides as cheap precursors and subsequentlyapplied aqueous ammonia to treat the catalyst sample, which resultedin a fractured morphology and reduced particle size. On this basis,we found out that as the alkaline solution varied, catalytic performancecorrelates closely with the surface acidity of MoVNbTeOx. By modulating acidity via impregnation with a traceamount of K2CO3, ethylene peroxidation can beeffectively suppressed by a 15% decrease in the ratio of ethyleneperoxidation rate to primary reaction rate. Compared with the conventionalMoVNbTeOx synthesized from salt solutions,this work retained the advantages of metal-oxide-synthesized MoVNbTeOx in terms of activity and cost, while substantiallyimproving the ethylene selectivity. By using this low-cost MoVNbTeOx catalyst, ODHE process can be operated at54% ethane conversion with 87% ethylene selectivity and a space–timeyield reaching 1.42 kgC2H4·kgcat–1·h–1, demonstrating a viable synthesis routefor the potential application of industrial catalysts.","PeriodicalId":100230,"journal":{"name":"Chem & Bio Engineering","volume":"3 9","pages":"809–818"},"PeriodicalIF":8.4,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Energy-Efficient Cascade Synthesis of Ammonia from Air via Spark Plasma-Mediated Nitrite Generation and CuRu Nanoalloy Electrocatalysis 火花等离子体介导亚硝酸盐生成及CuRu纳米合金电催化下空气中氨的高效级联合成

IF 8.4

Chem & Bio Engineering Pub Date : 2026-09-24 Epub Date: 2026-06-25 DOI: 10.1021/cbe.6c00044

Jian Sun, Bo Wu, Heyang Zhu, Shuyue Wang, Shaodong Zhou, Zhongjian Li, Lecheng Lei, Bin Yang

引用次数: 0

Sustainable Production of Succinic Acid through CO2 Conversion 通过CO2转化可持续生产琥珀酸

IF 8.4

Chem & Bio Engineering Pub Date : 2026-09-24 Epub Date: 2026-06-10 DOI: 10.1021/cbe.6c00021

Miao Miao, Zhaoxi Wang

引用次数: 0