Carbohydrate Polymer Technologies and Applications最新文献_第6页

Extraction and characterization of polysaccharide mixtures from Chlamydomonas reinhardtii: A case study as a consolidant for paper-based artworks

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-17 DOI: 10.1016/j.carpta.2025.100713

Annalisa Masi , Francesca Leonelli , Daniele Di Luca , Lorenzo Celio , Giulia Gasperuzzo , Sofia Lunardi , Carolina Rigon , Miriam Pitocco , Marcella Ioele , Maria Speranza Storace , Laura Medeghini , Amina Antonacci

{"title":"Extraction and characterization of polysaccharide mixtures from Chlamydomonas reinhardtii: A case study as a consolidant for paper-based artworks","authors":"Annalisa Masi , Francesca Leonelli , Daniele Di Luca , Lorenzo Celio , Giulia Gasperuzzo , Sofia Lunardi , Carolina Rigon , Miriam Pitocco , Marcella Ioele , Maria Speranza Storace , Laura Medeghini , Amina Antonacci","doi":"10.1016/j.carpta.2025.100713","DOIUrl":"10.1016/j.carpta.2025.100713","url":null,"abstract":"<div><div>Lately, microalgae use in cultural heritage conservation and protection has gained interest for their ability to meet the sector's innovation and sustainability demands, benefiting both the environment and practitioners.</div><div>An eco-friendly material, extracted from <em>Chlamydomonas reinhardtii</em> with hot water treatment and ethanol precipitation, for paper-based artwork conservation is presented. The study represents an advancement over the current state of the art, detailing the polysaccharide extract characterization and its validation in real application on samples. The polysaccharides' chemical composition was analyzed by spectroscopy and chromatography methods, revealing glucose (28 %), mannose (27 %), rhamnose (36 %), and xylose (9 %) mixture. The obtained bio-material was tested as a consolidant on artificially depolymerized paper samples and incoherent paint layers. Some commercial consolidants (Klucel G, Funori, Sturgeon glue, and crystalline nanocellulose) were used to compare and evaluate extract efficacy. The consolidating treatment was analyzed via optical and electron microscopy, mechanical strength quantification, and color alteration. The data obtained showed a breaking load increase (∼35 %) and no color variation, proving a notable consolidating capacity of the mixture on the artificially aged paper and pictorial film samples, compared with commercially available products. These findings show the potential of this polysaccharide extract as a sustainable solution for paper artwork conservation.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100713"},"PeriodicalIF":6.2,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143445560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Harnessing cyclodextrins for enhanced ocular delivery of carotenoid derivatives: From development to ex vivo characterization

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-17 DOI: 10.1016/j.carpta.2025.100718

Réka Angi , Attila János Kalóczkai , Anna Kovács , András Marton , Vivien Bárdos , Péter Dormán , Gábor Katona , Attila Agócs , Anita Csorba , Zoltán Zs. Nagy , Anna Vincze , György T. Balogh

{"title":"Harnessing cyclodextrins for enhanced ocular delivery of carotenoid derivatives: From development to ex vivo characterization","authors":"Réka Angi , Attila János Kalóczkai , Anna Kovács , András Marton , Vivien Bárdos , Péter Dormán , Gábor Katona , Attila Agócs , Anita Csorba , Zoltán Zs. Nagy , Anna Vincze , György T. Balogh","doi":"10.1016/j.carpta.2025.100718","DOIUrl":"10.1016/j.carpta.2025.100718","url":null,"abstract":"<div><div>Lutein and zeaxanthin, prominent carotenoids with antioxidant properties, contribute notably to maintaining of ocular health. These substances reduce the harmful effect of oxidative stress and blue light and ensure the vision quality. Carotenoids-rich dietary could have ophthalmic benefits, such as enhanced contrast perception and reduced eye fatigue, while also show potential in mitigating the risk of age-related macular degeneration (AMD). Nonetheless, ocular administration of carotenoids could enhance the local ophthalmic bioavailability of these compounds. The aim of this study was to investigate ophthalmic applicability of lutein (LutD) and zeaxanthin disuccinates (ZeaD) in aqueous solutions applying cyclodextrins to improve their solubility and permeability. Among the tested cyclodextrins, randomly methylated beta-cyclodextrin (RAMEB) was identified as the most effective solubilizing agent, achieving solubility values of 572±55 μM and 1470±103 μM for LutD and ZeaD, respectively. In vitro corneal-PAMPA and ex vivo porcine eye models demonstrated that RAMEB-based formulations significantly improved the permeability of both carotenoid derivatives by increasing their solubility (corneal concentration at 15 mins), markedly surpassing those of the reference suspensions. The findings suggest that RAMEB may be essential for developing carotenoid-based aqueous eye drops, leveraging its antioxidant properties to improve ocular health and ameliorate various degenerative eye conditions.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100718"},"PeriodicalIF":6.2,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143464109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimization of cellulose nanocrystals extraction from teff straw using acid hydrolysis followed by ultrasound sonication

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-17 DOI: 10.1016/j.carpta.2025.100707

Wubshet Alemu Woldie , Nurelegne Tefera Shibeshi , Kumsa Delessa Kuffi

{"title":"Optimization of cellulose nanocrystals extraction from teff straw using acid hydrolysis followed by ultrasound sonication","authors":"Wubshet Alemu Woldie , Nurelegne Tefera Shibeshi , Kumsa Delessa Kuffi","doi":"10.1016/j.carpta.2025.100707","DOIUrl":"10.1016/j.carpta.2025.100707","url":null,"abstract":"<div><div>This study presents a novel approach to optimizing the extraction of cellulose nanocrystals (CNCs) from <em>teff</em> straw, addressing the challenge of utilizing agricultural waste effectively. Employing a novel two-stage alkali treatment and bleaching process, enhanced cellulose purity from 39.27 % to 89.75 % while removing lignin. The optimized conditions for the acid hydrolysis were sulfuric acid a concentration of 63.8 %, temperature of 60 °C, and reaction time of 90 mins. This resulted with a minimum CNCs’ size of 31 nm and a maximum yield of 93.8 % w/w. Dynamic light scattering (DLS) analysis revealed the particle size distribution of the CNCs. FTIR and TGA confirmed the functional groups and thermal stability of the CNCs respectively. Scanning electron microscopy (SEM) showed the rod-like or whisker-like morphology of the CNCs. Moreover, X-ray diffraction (XRD) demonstrated that the acid hydrolysis highly affected the amorphous regions of the cellulose. The higher specific surface area, 125 m<sup>2</sup>, and improved cross-linking potential of the CNCs make them attractive for packaging applications. Furthermore, the CNCs exhibited excellent mechanical, thermal, and barrier properties. A statistical analysis supports the robustness of the extraction model, with R-squared values indicating strong predictive capability (R² = 0.992, adjusted R² = 0.983, predicted R² = 0.903).</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100707"},"PeriodicalIF":6.2,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143454826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alginate-gelatin composite hydrogels for encapsulating Aloe vera extract; optimization, characterization, and release kinetics

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-17 DOI: 10.1016/j.carpta.2025.100717

Shahrzad Ameli , Moloud Nourani , Nafiseh Bakhshi , Bahareh Salemi , Elham Assadpour , Seid Mahdi Jafari

{"title":"Alginate-gelatin composite hydrogels for encapsulating Aloe vera extract; optimization, characterization, and release kinetics","authors":"Shahrzad Ameli , Moloud Nourani , Nafiseh Bakhshi , Bahareh Salemi , Elham Assadpour , Seid Mahdi Jafari","doi":"10.1016/j.carpta.2025.100717","DOIUrl":"10.1016/j.carpta.2025.100717","url":null,"abstract":"<div><div>Composite alginate (ALG) hydrogels offer a promising solution to the rapid release challenges of encapsulated materials. This study developed ALG-gelatin (GE) hydrogels loaded with Aloe vera extract (AVE). A Resolution-V fractional factorial design and response surface methodology were employed to explore the impact of AVE and CaCl<sub>2</sub> concentrations, hardening time, and the inclusion of GE as a wall material on the encapsulation efficiency (EE (%)) of the hydrogels. The optimal formulation identified was AVE at 4.41 %, CaCl<sub>2</sub> concentration at 600 mM, and a hardening time of one hour, achieving the highest EE (%) of 93.16 %. Fourier transform infrared (FTIR) spectroscopy revealed chemical interactions between AVE and the ALG-GE capsules. Scanning electron microscopy of the ALG-GE hydrogel exhibited a rougher surface compared to calcium ALG hydrogels, characterized by the absence of surface cracks, reduced surface pores, and a meshed appearance, all contributing to the improved EE (%). The release rate of AVE from the hydrogels peaked at 70 °C and pH = 3, as indicated by an elevated release rate constant. These findings suggest that the ALG-GE hydrogel beads may serve as effective carriers for bioactive compounds, offering valuable insights for the formulation of enhanced delivery systems for these compounds in food applications.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100717"},"PeriodicalIF":6.2,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143437411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of heat generation and mixed convection on the dextrin type flow near a stretching cylinder

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-17 DOI: 10.1016/j.carpta.2025.100720

T. Salahuddin , Aqib Javed , Muhammad Awais , Mair Khan , M. Afzal

{"title":"Role of heat generation and mixed convection on the dextrin type flow near a stretching cylinder","authors":"T. Salahuddin , Aqib Javed , Muhammad Awais , Mair Khan , M. Afzal","doi":"10.1016/j.carpta.2025.100720","DOIUrl":"10.1016/j.carpta.2025.100720","url":null,"abstract":"<div><div>In this work, we considered the two -dimensional cylindrical coordinate system for the mixed convection flow Carreau fluid model moving on the stretching cylinder. Further, the nanoparticles are embedded in the Carreau fluid model to analyze the enhanced thermal characteristics of flow and this type of study is useful because the nanofluids helps in the regulation of heat in gasoline engines and machines by preventing corrosion in the cooling system and aiding in the removal of waste heat. The CattaneoChristov heat and mass fluxes is considered instead of traditional Fourier and Fick's law of heat conduction, as this model can investigate the temperature changes during small time intervals. The inspection of thermal and solutal region are observed by heat general and chemical reaction. There is need to conduct a study in which the combined effects of heat and mass transfer in terms of Carreau fluid model along with the CattaneoChristov heat and mass flux, and other considered factors are considered because it helps in better understanding of design systems involving nanofluids, such as heat exchangers or reactors, where non-Newtonian behavior, enhanced heat transfer, and chemical processes are significant. The mathematical equations are converted into differential equations by using similarity conversions, which are numerically solved by using the bvp4c function in MATLAB. The graphical outcomes of emergent parameters on the corresponding fields are discussed<strong>.</strong></div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"10 ","pages":"Article 100720"},"PeriodicalIF":6.2,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cellulose nanofiber-reinforced chitosan/PVA/MXene (Ti3C2Tx) membrane: Enhanced multifunctional performance and non-cytotoxicity for drug delivery

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-13 DOI: 10.1016/j.carpta.2025.100712

Thanaphorn Rakkan , Winita Punyodom , Puttinan Meepowpan , Yottha Srithep , Sarinthip Thanakkasaranee , Pornchai Rachtanapun , Kittisak Jantanasakulwong , Patnarin Worajittiphon

{"title":"Cellulose nanofiber-reinforced chitosan/PVA/MXene (Ti3C2Tx) membrane: Enhanced multifunctional performance and non-cytotoxicity for drug delivery","authors":"Thanaphorn Rakkan , Winita Punyodom , Puttinan Meepowpan , Yottha Srithep , Sarinthip Thanakkasaranee , Pornchai Rachtanapun , Kittisak Jantanasakulwong , Patnarin Worajittiphon","doi":"10.1016/j.carpta.2025.100712","DOIUrl":"10.1016/j.carpta.2025.100712","url":null,"abstract":"<div><div>The development of wound dressings is crucial for advancing human healthcare, requiring materials that meet specific performance criteria. This study presents a novel electrospun membrane composed of chitosan (CS), poly(vinyl alcohol) (PVA), cellulose nanofibers (CNF), and MXene (Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub>), designed for the release of quercetin (QE, 0.3 phr). Incorporating CNF (1.5 phr) improved the mechanical properties of the CS/PVA membrane, which were further enhanced by the addition of MXene (2.0 phr), resulting in superior mechanical properties compared to the CS/PVA/CNF membrane. Significant improvements included enhanced ultimate tensile strength (8.57 ± 0.08 MPa), Young's modulus (55.80 ± 1.02 MPa), and toughness (1904.49 ± 2.54 kJ/m<sup>3</sup>). MXene also promoted QE release, achieving 90.87 ± 0.04 %, facilitated by the high swelling degree of the membrane (362.49 ± 12.81 %). The CS/PVA/CNF/MXene/QE membrane exhibited significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity (89.63 ± 0.11 %) and thermal stability, withstanding service temperatures up to 276.5 °C. Its biocompatibility was confirmed by a 92.83 ± 1.88 % cell viability of mouse fibroblast L929 cells after 72 h. Additionally, the CS/PVA/CNF/MXene/QE membrane demonstrated effective antibacterial properties, reducing colonies of <em>Staphylococcus aureus</em> ATCC 25923 by 83.15 ± 1.54 % and <em>Escherichia coli</em> DMST 703 by 74.49 ± 4.49 %. The enhanced properties and improved QE delivery performance of the composite membrane with CNF and MXene highlight its potential as a promising candidate for advanced wound dressing applications.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100712"},"PeriodicalIF":6.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143488416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aloe barbadensis polymeric acetylated mannan modified by self-assembly through a pervaporation aloe polysaccharide membrane: Safety evaluation and tail fin regeneration in zebrafish

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-13 DOI: 10.1016/j.carpta.2025.100709

Di Li , Jiajie Deng , Mengmeng Wang , Haiyang Yin , Jinzi Chen , Weijie Xu , Xiaofeng Guo , Xueli Tong , Ding Ye , Jiejing Li

{"title":"Aloe barbadensis polymeric acetylated mannan modified by self-assembly through a pervaporation aloe polysaccharide membrane: Safety evaluation and tail fin regeneration in zebrafish","authors":"Di Li , Jiajie Deng , Mengmeng Wang , Haiyang Yin , Jinzi Chen , Weijie Xu , Xiaofeng Guo , Xueli Tong , Ding Ye , Jiejing Li","doi":"10.1016/j.carpta.2025.100709","DOIUrl":"10.1016/j.carpta.2025.100709","url":null,"abstract":"<div><div>Aloe vera has a remarkable anti-inflammation effect in wound healing and other skin disorders. Its bioactivity is mainly attributed to the polysaccharides. However, the clinical applications of aloe vera are considerably restricted by the low efficacy of its extracts. To increase its bioactivity, it is necessary to develop de novo techniques for extracting and modifying aloe polysaccharides. This study used pervaporation to perform self-assembly of aloe vera polysaccharides, leading to the production of aloe barbadensis polymeric acemannan 2 (ABPA2). ABPA2 was associated with increasing of acytel functional groups compared to ABPA1. Electron microscopic analysis showed ABPA2 was able to form supporting membrane. The safety of ABPA2 was evaluated through acute and chronic toxicity experiments. Functionally, it was able to induce zebrafish tail fin healing after wounding. The effects were in all likelihood ascribed to its ability to induce proliferation and macrophage extravasation in wounded tail fin. By applying RNA-seq, it showed that ABPA2 triggered multiple types of cells differentiated and proliferation mainly through regulating genes expression of extracellular matrix. After all it was able to activate mitochondrial biogenesis through regulating mechanotransduction of calcium. These findings warrant a further chemical-biological investigation in mammalian wound healing.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"10 ","pages":"Article 100709"},"PeriodicalIF":6.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143601371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of clay/alginate/chondroitin sulfate composite microspheres via continuous process for chronic wounds regeneration

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-13 DOI: 10.1016/j.carpta.2025.100711

Cristian Nomicisio , Marco Ruggeri , Christine Taviot-Guého , Cinzia Boselli , Antonia Icaro Cornaglia , Eleonora Bianchi , Elena Del Favero , Caterina Ricci , Giuseppe Firpo , Barbara Vigani , Paolo Vacca , César Viseras , Silvia Rossi , Giuseppina Sandri

{"title":"Development of clay/alginate/chondroitin sulfate composite microspheres via continuous process for chronic wounds regeneration","authors":"Cristian Nomicisio , Marco Ruggeri , Christine Taviot-Guého , Cinzia Boselli , Antonia Icaro Cornaglia , Eleonora Bianchi , Elena Del Favero , Caterina Ricci , Giuseppe Firpo , Barbara Vigani , Paolo Vacca , César Viseras , Silvia Rossi , Giuseppina Sandri","doi":"10.1016/j.carpta.2025.100711","DOIUrl":"10.1016/j.carpta.2025.100711","url":null,"abstract":"<div><div>Chronic wounds significantly affect the quality of life of millions of people, generating substantial problems for the patients and for health care systems. Therefore, this work focuses on the development of microparticles based on alginate and chondroitin sulfate which were doped with layered double hydroxides (LDH), anionic clay minerals, based on Zn and Al. The obtained clay/polysaccharide composite materials could provide enhanced properties for wound healing, in particular related to cell adhesion and proliferation. The microparticles were manufactured by spray drying and crosslinked using CaCl<sub>2</sub> to obtain insoluble scaffolds for application in the physiological environment. The materials and the process were chosen continuous manufacturing in the industrial field. The mean diameter of the obtained microparticles ranged from 10 to 15 µm with a narrow dimensional distribution. Solid state characterizations (XRD, FTIR, SAXS, TGA/DSC) confirmed the LDH doping in a concentration of around 5 %w/w. The presence of LDH enhanced the stability of the systems in aqueous environment, increasing the wettability and decreasing the zeta potential due to their positive charge. Preclinical in vitro studies suggested a positive impact of LDH doping which led to a cell proliferation increase of around 15 %. In vivo studies demonstrated the safety and efficacy of the systems, suggesting the potential of this platform for therapeutic use.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"10 ","pages":"Article 100711"},"PeriodicalIF":6.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143609921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pectin from fruit peel: A comprehensive review on various extraction approaches and their potential applications in pharmaceutical and food industries

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-11 DOI: 10.1016/j.carpta.2025.100708

Snigdha Satabdi Dixit , L. Muruganandam , I. Ganesh Moorthy

{"title":"Pectin from fruit peel: A comprehensive review on various extraction approaches and their potential applications in pharmaceutical and food industries","authors":"Snigdha Satabdi Dixit , L. Muruganandam , I. Ganesh Moorthy","doi":"10.1016/j.carpta.2025.100708","DOIUrl":"10.1016/j.carpta.2025.100708","url":null,"abstract":"<div><div>The complex heteropolysaccharide pectin has become a versatile biological polymer with possible applications in the pharmaceutical and food industries. Pectin has a lot of potential applications in cancer treatment as well. Pectin is an underutilized resource that is abundant and renewable. Understanding pectin's physicochemical qualities and functional features necessitates an awareness of its structural characterization, which includes metrics such as degree of esterification, molecular weight, and functional groups. This study thoroughly investigates the process of removing pectin from fruit peels, purifying, and characterizing. The effectiveness of extraction processes, including established and novel approaches, is evaluated closely to determine how they affect pectin production and quality. The detailed discussion includes further purifying procedures to eliminate impurities and improve pectin characteristics. This study addresses the practical applications of pectin as a texturizing agent in the food sector and its possible effectiveness in the pharmaceutical industry as a bioactive molecule and drug delivery carrier. To promote the creation of sustainable and high-value pectin-based products, difficulties related to pectin extraction, purification, and characterization are noted, along with possible directions for further study.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100708"},"PeriodicalIF":6.2,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143463971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancements in characterization and preclinical applications of hyaluronic acid-based biomaterials for wound healing: A review

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-10 DOI: 10.1016/j.carpta.2025.100706

Marjan Talebi , Rouzbeh Almasi Ghale , Roghayeh Mokhtari Asl , Fatemeh Tabandeh

{"title":"Advancements in characterization and preclinical applications of hyaluronic acid-based biomaterials for wound healing: A review","authors":"Marjan Talebi , Rouzbeh Almasi Ghale , Roghayeh Mokhtari Asl , Fatemeh Tabandeh","doi":"10.1016/j.carpta.2025.100706","DOIUrl":"10.1016/j.carpta.2025.100706","url":null,"abstract":"<div><div>Wound healing involves replacing damaged tissue with new, healthy tissue. While conventional dressings are used, more effective solutions are needed, especially for chronic wounds. This review offers a comprehensive update on newly developed hyaluronic acid-based biomaterials used in the wound healing process focusing on preclinical aspects. Biomaterials play a pivotal role in modern wound healing applications, with hyaluronic acid (HA) emerging as a promising component in advanced dressing technologies. HA, a glycosaminoglycan, is crucial for inflammatory responses, angiogenesis, and tissue regeneration. We discuss how molecular weight, concentration, and chemical modifications affect the properties of HA-based dressings. Additionally, we explore the potential of combining HA with other biomaterials and the development of sustained release systems. The biocompatibility, biodegradability, and hydrophilic properties of HA facilitate its incorporation into various wound dressing materials such as sponges, hydrogels, films, and electrospun membranes. Notably, HA-based hydrogel dressings can be used throughout all four stages of wound healing. This study highlights the roles of natural and synthetic biomaterials in wound dressings, and the potential applications of HA in treating infection, diabetic wounds, burns, and pain management. Furthermore, clinical prospects for wound healing with HA are elaborated upon.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100706"},"PeriodicalIF":6.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143463970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0