Carbohydrate Polymer Technologies and Applications最新文献_第6页

Quantitative evaluation of release behavior of synthetic taste-masking drugs using polysaccharide-based carrier with direct analysis in real-time mass spectrometry 实时质谱法直接分析多糖基载体对合成掩味药物释放行为的定量评价

IF 6.5

Carbohydrate Polymer Technologies and Applications Pub Date : 2026-03-01 Epub Date: 2026-01-07 DOI: 10.1016/j.carpta.2026.101085

Zhao-Liang Hu , Ke Wang , Xiao-Hua Zhou , Xun Zhao , Mei Zhang , Yao-Zuo Yuan , Wen-Yuan Liu , Bao-Cheng Wang , Lei Chen , Sheng Tang , Hian Kee Lee , Hai-Wei Shi , Sheng-Jin Gong

{"title":"Quantitative evaluation of release behavior of synthetic taste-masking drugs using polysaccharide-based carrier with direct analysis in real-time mass spectrometry","authors":"Zhao-Liang Hu , Ke Wang , Xiao-Hua Zhou , Xun Zhao , Mei Zhang , Yao-Zuo Yuan , Wen-Yuan Liu , Bao-Cheng Wang , Lei Chen , Sheng Tang , Hian Kee Lee , Hai-Wei Shi , Sheng-Jin Gong","doi":"10.1016/j.carpta.2026.101085","DOIUrl":"10.1016/j.carpta.2026.101085","url":null,"abstract":"<div><div>Sodium alginate (ALG) is widely used as a taste-masking excipient in pediatric oral formulations, yet its release behavior is strongly governed by molecular structure. azithromycin (AZM, targeted bitterness probes)-loaded ALG microspheres using five different ALG specifications (with various molecular weights or mannuronic-to-guluronic acid (M/G) ratios) were prepared, with loading efficiencies between 17.71–19.48%. Thereafter, an on-line release-evaluation method was developed by integrating a flow-pump dissolution model with direct analysis in real time mass spectrometry (DART-MS), enabling dynamic monitoring of AZM release under simulated oral conditions. Consequently, both molecular weights and M/G ratios were verified that can significantly affect the release behavior of the microspheres. Microspheres prepared by ALG with lower M/G ratios showed consistently limited release across the 1200-s testing period, reaching approximately 3% cumulative release. In contrast, those derived from ALG with higher M/G ratios displayed faster initial release during 0–300 s and achieved approximately 12% cumulative release at 1200 s. Molecular weight further modulated late-stage release, with lower-molecular-weight ALG samples exhibiting more significant increases in total AZM release. This approach offers a quantitative and mechanism-supported framework for optimizing polysaccharide-based taste-masking systems and achieving controlled drug release in pediatric formulations.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"13 ","pages":"Article 101085"},"PeriodicalIF":6.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145977595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bottom-up assembly of cellulose nanocrystals as a green entry to structured functional carbons 纤维素纳米晶体的自下而上组装作为结构功能碳的绿色入口

IF 6.5

Carbohydrate Polymer Technologies and Applications Pub Date : 2026-03-01 Epub Date: 2025-12-29 DOI: 10.1016/j.carpta.2025.101080

Lucas Güemes , Víctor Calvo , Vanessa B. Maya-Segura , Elísabet Pires , Wolfgang K. Maser , Ana M. Benito , Enrique García-Bordejé , José M. González-Domínguez

{"title":"Bottom-up assembly of cellulose nanocrystals as a green entry to structured functional carbons","authors":"Lucas Güemes , Víctor Calvo , Vanessa B. Maya-Segura , Elísabet Pires , Wolfgang K. Maser , Ana M. Benito , Enrique García-Bordejé , José M. González-Domínguez","doi":"10.1016/j.carpta.2025.101080","DOIUrl":"10.1016/j.carpta.2025.101080","url":null,"abstract":"<div><div>The bottom-up assembly of cellulose nanocrystals (CNCs) into porous scaffolds offers a sustainable route to translate their intrinsic properties into functional 3D materials. This strategy enables precise control over porous architectures, unlocking opportunities for high-performance materials tailored to specific applications. Here, we present the fabrication of structured carbons derived from nanocellulose precursors. CNCs are isolated from cellulosic feedstock in type-I and type-II crystalline allomorphs via a one-pot synthesis process followed by minimal processing steps. The resulting aqueous CNC colloids self-assemble into cross-linked hydrogels through controlled hydrothermal aggregation, followed by lyophilization to produce macroporous aerogels (bulk porosities up to 98%). Each allomorph exhibits distinct aggregation behavior, explored for the first time with type-II CNCs. As proof of concept, these aerogels undergo pyrolysis at varying temperatures and subsequent sulfonation, yielding highly porous carbons functionalized with sulfonic acid groups (functionalization degree of ca. 2400 μmol·g<sup>−1</sup>). The resulting materials combine macroporosity from hydrothermal assembly with microporosity generated during pyrolysis and sulfonation, forming a hierarchical structure ideal for catalytic applications. Their performance is demonstrated in solketal synthesis (yielding ∼90% of solketal in consecutive cycles after 4 h at room temperature) positioning CNC-based sulfonated aerogels as a greener alternative to conventional Brønsted acid catalysts and surpassing classical activated carbons in sustainability and design.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"13 ","pages":"Article 101080"},"PeriodicalIF":6.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145926214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chitooligosaccharides promote intestinal adhesion of Clostridium butyricum and enhance gut health, immunity, and antioxidant capacity in largemouth bass 壳寡糖促进丁酸梭菌肠道黏附，增强大口黑鲈肠道健康、免疫力和抗氧化能力

IF 6.5

Carbohydrate Polymer Technologies and Applications Pub Date : 2026-03-01 Epub Date: 2025-12-22 DOI: 10.1016/j.carpta.2025.101076

Ge Bai , Xiaohu Li , Honghao Ding , Diying Li , Keke Li , Wen Zhou , Yunxiang Liang , Yingjun Li

{"title":"Chitooligosaccharides promote intestinal adhesion of Clostridium butyricum and enhance gut health, immunity, and antioxidant capacity in largemouth bass","authors":"Ge Bai , Xiaohu Li , Honghao Ding , Diying Li , Keke Li , Wen Zhou , Yunxiang Liang , Yingjun Li","doi":"10.1016/j.carpta.2025.101076","DOIUrl":"10.1016/j.carpta.2025.101076","url":null,"abstract":"<div><div>Prebiotic polysaccharides and oligosaccharides serve as critical modulators of probiotic functionality, influencing gut microbial ecology and host physiological responses. This study aimed to identify a high-efficacy prebiotic for enhancing the proliferation and intestinal adhesion of <em>Clostridium butyricum</em> (CB) among multiple polysaccharides and to evaluate its impact of combined treatment with CB in largemouth bass (<em>Micropterus salmoides</em>). Through systematic screening, chitooligosaccharides (COS) were selected due to their superior ability to promote CB growth and adhesion. Although no significant differences in growth performance were observed among groups, dietary supplementation with COS and CB in combination reduced hepatic stress markers (ALT: –75.8 %; AST: –83.8 %) and significantly improved intestinal antioxidant capacity (GSH-Px: +282.4 %; T-AOC: +121.0 %; MDA: –34.3 %). RT-qRCR analysis revealed profound upregulation of tight junction proteins (Claudin-1, Claudin-4, ZO-1), indicating enhanced barrier integrity. Hepatic cytokine profiling showed strong immunomodulatory effects, with suppression of IL-1β and IL-8 by 75.7 % and 73.6 %, respectively, and upregulation of IL-10 (2.29-fold) and TCR-α/β (3–4-fold). Gut microbiome restructuring featured a reduction in <em>Pseudomonadota</em> and enrichment of beneficial <em>Bacillota</em>. These results demonstrate that combined COS and CB supplementation improved intestinal barrier function, antioxidant capacity, and immunomodulation, and modulated gut microbiota, suggesting its potential as a sustainable strategy for aquaculture.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"13 ","pages":"Article 101076"},"PeriodicalIF":6.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145926144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibiofilm activity of lactose and κ-carrabiose chitosan derivates 乳糖和κ- carcarose壳聚糖衍生物的抗膜活性

IF 6.5

Carbohydrate Polymer Technologies and Applications Pub Date : 2026-03-01 Epub Date: 2026-01-01 DOI: 10.1016/j.carpta.2025.101082

Romina Cingolani , Fernanda Buzzola , Diego A. Navarro

{"title":"Antibiofilm activity of lactose and κ-carrabiose chitosan derivates","authors":"Romina Cingolani , Fernanda Buzzola , Diego A. Navarro","doi":"10.1016/j.carpta.2025.101082","DOIUrl":"10.1016/j.carpta.2025.101082","url":null,"abstract":"<div><div>The use of natural polysaccharides, particularly chitosan and its derivatives, as agents to prevent biofilm formation and attenuate virulence properties of pathogenic bacteria has received increasing attention in recent years. In this study chitosan and some selected derivatives were tested for their antibacterial activity, with a N-alkylated lactose chitosan derivative and a N-alkylated κ-carrabiose chitosan derivative showing promising results as inhibitors of in vitro biofilm formation in the bacterial strain <em>Staphylococcus aureus</em> ATCC25923. In combination with the antibiotic ciprofloxacin, the selected lactose derivative showed a reduction in biofilm formation compared to the use of the antibiotic alone and was effective in alleviating the enhancement of biofilm formation that arrives as an unwanted effect of the antibiotic use. The novel κ-carrabiose-chitosan derivatives were synthesized using response surface methodology (RSM) and products with different degrees of substitution were obtained in a controlled manner. The reaction conditions were selected based on the prior optimization by RSM of the influential variables (reagent concentrations, volume, time and temperature) in the synthesis of lactose-chitosan derivatives. The reductive amination reaction using 2-picoline borane as a reducing agent was selected to achieve the synthesis of the chitosan derivatives, making the reaction and work-up greener and safer.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"13 ","pages":"Article 101082"},"PeriodicalIF":6.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145926211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tunable core water–shell alginate microparticles produced by microfluidics for sustained doxorubicin encapsulation and release 微流体制备的可调核心水壳藻酸盐微颗粒用于阿霉素的持续包封和释放

IF 6.5

Carbohydrate Polymer Technologies and Applications Pub Date : 2026-03-01 Epub Date: 2026-01-08 DOI: 10.1016/j.carpta.2026.101086

Fatemeh Zarei , Amir Shamloo

{"title":"Tunable core water–shell alginate microparticles produced by microfluidics for sustained doxorubicin encapsulation and release","authors":"Fatemeh Zarei , Amir Shamloo","doi":"10.1016/j.carpta.2026.101086","DOIUrl":"10.1016/j.carpta.2026.101086","url":null,"abstract":"<div><div>Core–shell particles have emerged as a promising platform for drug delivery due to their ability to spatially separate the drug-loaded core from the protective shell, enabling enhanced encapsulation efficiency, protection of sensitive therapeutics, and precise control over release kinetics. This study aimed to develop and optimize a droplet-based microfluidic approach for synthesizing water core–alginate shell particles. To mitigate the limitation of hydrophilic drug retention, these microparticles were designed to encapsulate the anticancer drug doxorubicin, enabling sustained release and reducing adverse side effects. Key parameters—including the flow rate of various phases, the junction width of the flow-focusing device, and the composition of alginate shell solution— were evaluated to achieve stable core–shell microgels with the desired morphology. By adjusting these parameters, monodisperse core-shell droplets (350 µm diameter, 43 µm shell thickness) were successfully tuned to slow drug release and increase resistance to immediate drug diffusion. To prolong the release duration, carboxymethyl cellulose particles and ε-poly-<span>l</span>-lysine were added to the core phase to form interpenetrating networks and electrostatic complexes at the water/alginate interface. This structural modification significantly enhanced drug encapsulation from approximately 67% to over 92%, while simultaneously prolonging the release duration beyond 120 hours under physiological conditions. Finally, the produced core-shell drug carriers were utilized for treating cancer cells, indicating a predictable and sustained cytotoxic effect against cancer cells. Overall, the proposed approach enables reproducible fabrication of tunable core–shell carriers with precise control over structural and functional parameters, offering promise for sustained chemotherapy delivery with reduced side effects.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"13 ","pages":"Article 101086"},"PeriodicalIF":6.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146022662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Self-crosslinked fucoidan nanoparticles via electron beam irradiation: Synthesis, physicochemical analysis, and drug delivery application 电子束辐照下的自交联岩藻聚糖纳米颗粒：合成、理化分析和给药应用

IF 6.5

Carbohydrate Polymer Technologies and Applications Pub Date : 2026-03-01 Epub Date: 2025-12-31 DOI: 10.1016/j.carpta.2025.101081

Kyung Won Kim , Heeyeol Lee , Seung Tae Jung , Wan Ook Kim , Seongwhan Cho , Phuong Tu Huynh , Muhammad Zeeshan , Yuri Kim , Dong-Mok Lee , Jinku Kim , Kwang Soo Cho , Jeongsoo Yoo

{"title":"Self-crosslinked fucoidan nanoparticles via electron beam irradiation: Synthesis, physicochemical analysis, and drug delivery application","authors":"Kyung Won Kim , Heeyeol Lee , Seung Tae Jung , Wan Ook Kim , Seongwhan Cho , Phuong Tu Huynh , Muhammad Zeeshan , Yuri Kim , Dong-Mok Lee , Jinku Kim , Kwang Soo Cho , Jeongsoo Yoo","doi":"10.1016/j.carpta.2025.101081","DOIUrl":"10.1016/j.carpta.2025.101081","url":null,"abstract":"<div><div>Naturally derived polysaccharides have great potential in biomedical applications due to their biocompatibility, biodegradability, and non-toxicity. In this study, we successfully synthesized nanoparticles of fucoidan, a sulfated polysaccharide derived from brown algae, via electron beam irradiation. This method enabled simple and efficient synthesis in aqueous solution without the need for chemical cross-linkers or toxic reagents. By adjusting the electron beam irradiation intensity and fucoidan concentration, the nanoparticle size could be tuned from 100 to 215 nm. Structural analysis (FT-IR, <sup>1</sup>H-NMR, XRD) confirmed that irradiation led to increased crystallinity and cross-linking. Additionally, rheological analysis suggested a mechanism by which electron beam irradiation induced simultaneous chain scission and cross-linking. Doxorubicin loading into the nanoparticles resulted in pH-sensitive drug release properties, demonstrating stability at physiological pH and accelerated release under acidic conditions. In cell and animal assays, the doxorubicin-loaded nanoparticles exhibited high cytotoxicity against EMT6 breast cancer cells and reduced tumor volume by more than four-fold in vivo. This study presents a green and scalable method for preparing fucoidan nanoparticles using electron beam irradiation; it demonstrates their potential applications in cancer therapy and drug delivery systems.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"13 ","pages":"Article 101081"},"PeriodicalIF":6.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146022663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Azo-functionalized chitosan porous films: A sustainable approach for enhanced CO2 capture and selectivity 偶氮功能化壳聚糖多孔膜：一种增强CO2捕获和选择性的可持续方法

IF 6.5

Carbohydrate Polymer Technologies and Applications Pub Date : 2026-03-01 Epub Date: 2026-01-29 DOI: 10.1016/j.carpta.2026.101092

Sebastian Bonardd , Cristina del Mar García Martín , José Ignacio Hernández García , Bikash Mishra , Óscar Ramírez , David Díaz Díaz

{"title":"Azo-functionalized chitosan porous films: A sustainable approach for enhanced CO2 capture and selectivity","authors":"Sebastian Bonardd , Cristina del Mar García Martín , José Ignacio Hernández García , Bikash Mishra , Óscar Ramírez , David Díaz Díaz","doi":"10.1016/j.carpta.2026.101092","DOIUrl":"10.1016/j.carpta.2026.101092","url":null,"abstract":"<div><div>The need for efficient and sustainable CO<sub>2</sub> capture technologies has driven extensive research into different porous materials as adsorbents. However, many of the best-performing materials are derived from petroleum-based precursors, creating a fundamental contradiction in terms of environmental sustainability. Herein, we present a biopolymer-based approach for CO<sub>2</sub> capture by chemically modifying porous chitosan films with azo functionalities. The functionalization, achieved via imine linkages, was confirmed through FTIR, NMR, and UV–Vis, while SEM and TEM verified the preservation of the films’ porous architecture. Thermal stability assessments demonstrated that the azo-modified films retained excellent resistance to degradation, with an onset degradation temperature (T<em><sub>i</sub></em>) of 279 °C. The introduction of azo groups resulted in a significant enhancement of both CO<sub>2</sub> capture capacity, achieving values of 1.51 mmol g⁻<sup>1</sup> at 273 K and 0.65 mmol g⁻<sup>1</sup> at 298 K, corresponding to an approximate tenfold enhancement compared to pristine chitosan. This modification imparted a favorable N<sub>2</sub>-phobic/CO<sub>2</sub>-philic character /N<sub>2</sub> selectivity, as evidenced by a noticeable reduction in adsorption from 0.12 to 0.08 mmol g⁻<sup>1</sup> at 298 K. This work provides a sustainable and scalable platform for developing next-generation CO<sub>2</sub> adsorbents, paving the way for further studies on their adsorption performance and long-term usability under real-world conditions.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"13 ","pages":"Article 101092"},"PeriodicalIF":6.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146173521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cellulose-MOFs hybrid materials: Chemistry and mechanism of applications in biomedical - A review 纤维素- mofs杂化材料：化学性质及其在生物医学中的应用机理综述

IF 6.5

Carbohydrate Polymer Technologies and Applications Pub Date : 2026-03-01 Epub Date: 2026-01-23 DOI: 10.1016/j.carpta.2026.101090

Atanu Kumar Das , Rupak Kumar Ghosh , Austin J. Conte , Afroza Akter Liza , Sumaya Haq Mim , Md Nazrul Islam , Jiaqi Guo , Roni Maryana , Arthur J. Ragauskas

{"title":"Cellulose-MOFs hybrid materials: Chemistry and mechanism of applications in biomedical - A review","authors":"Atanu Kumar Das , Rupak Kumar Ghosh , Austin J. Conte , Afroza Akter Liza , Sumaya Haq Mim , Md Nazrul Islam , Jiaqi Guo , Roni Maryana , Arthur J. Ragauskas","doi":"10.1016/j.carpta.2026.101090","DOIUrl":"10.1016/j.carpta.2026.101090","url":null,"abstract":"<div><div>Rising costs and performance limits of modern biomedical materials motivate the search for advanced, biocompatible alternatives. Cellulose-based metal-organic frameworks (cellulose-MOFs) emerge as distinctive hybrids combining renewable polymer chemistry with tunable porous architectures, enabling uncommon structure–function relationships. Their large surface area, controllable pore size, adaptable functional groups, and efficient host–guest interactions underpin diverse biomedical functions. Till now, no comprehensive, application-focused review has systematically summarized cellulose-MOFs synthesis for biomedical applications. This review critically analyzes cellulose-MOFs, emphasizing mechanistic links between chemistry, synthesis routes, interfacial interactions, and biomedical performance, rather than cataloging applications alone. Antibacterial action, targeted drug delivery, and sensing/biosensing are discussed through comparative insights. The article identifies unresolved challenges and proposes future research pathways to rationally design next-generation cellulose-MOFs systems, guiding researchers and clinicians alike.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"13 ","pages":"Article 101090"},"PeriodicalIF":6.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146173525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of UV-resistant carboxymethyl cellulose/ZnONPs based nanocomposite films derived from Zea mays husk and reinforced with Ananas comosus peel extract for active food packaging 玉米皮增强抗紫外羧甲基纤维素/ZnONPs纳米复合膜的研制

IF 6.5

Carbohydrate Polymer Technologies and Applications Pub Date : 2026-03-01 Epub Date: 2026-01-05 DOI: 10.1016/j.carpta.2026.101083

Md Abu Rayhan, Md. Murad Hossain, Tamanna Rahman, Md. Suhel Mia, Wahidu Zzaman

{"title":"Development of UV-resistant carboxymethyl cellulose/ZnONPs based nanocomposite films derived from Zea mays husk and reinforced with Ananas comosus peel extract for active food packaging","authors":"Md Abu Rayhan, Md. Murad Hossain, Tamanna Rahman, Md. Suhel Mia, Wahidu Zzaman","doi":"10.1016/j.carpta.2026.101083","DOIUrl":"10.1016/j.carpta.2026.101083","url":null,"abstract":"<div><div>The increasing environmental burden of petroleum-based packaging underscores the need for biodegradable materials with enhanced functional performance. This study reports the development of composite films from carboxymethyl cellulose (CMC) derived from <em>Zea mays</em> husk, reinforced with zinc oxide nanoparticles (ZnO<img>NPs) and <em>Ananas comosus</em> peel extract (APE). Films were fabricated using a fixed ZnO<img>NPs concentration (5 wt % relative to CMC) and varying APE contents (5–15 % wt % relative to CMC), and their physicochemical, structural, and functional properties were systematically evaluated. The findings indicated that the CMC-ZnO-APE 10 % film exhibited optimal performance, with tensile strength increasing to 26.05 MPa, and water vapor permeability decreased by 32 %, along with lower moisture sensitivity, enhanced thermal stability with degradation onset above 200 °C, and near-complete UV shielding. Antioxidant activity (DPPH radical scavenging) increased to 45.99 %, while effective antimicrobial inhibition against <em>Staphylococcus aureus</em> and <em>Escherichia coli</em> was observed. Additionally, high biodegradability of the polymeric matrix was achieved, with over 96 % weight loss after three weeks of soil burial. Structural analyses confirmed uniform nanoparticle dispersion within the CMC matrix. These findings advance the novelty of valorizing <em>Zea mays</em> husk and <em>Ananas comosus</em> peel into high-performance, biodegradable films with strong potential for sustainable food packaging applications.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"13 ","pages":"Article 101083"},"PeriodicalIF":6.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145977597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sulfated modification and biomedical applications of β-glucans: A review β-葡聚糖的磺化改性及其生物医学应用综述

IF 6.5

Carbohydrate Polymer Technologies and Applications Pub Date : 2026-03-01 Epub Date: 2025-12-06 DOI: 10.1016/j.carpta.2025.101063

Zeming Zhang , Haoyu Wang , Mengqing Li , Yuxuan Liu , Kaiping Wang , Jinglin Wang

{"title":"Sulfated modification and biomedical applications of β-glucans: A review","authors":"Zeming Zhang , Haoyu Wang , Mengqing Li , Yuxuan Liu , Kaiping Wang , Jinglin Wang","doi":"10.1016/j.carpta.2025.101063","DOIUrl":"10.1016/j.carpta.2025.101063","url":null,"abstract":"<div><div>β-glucans, a type of naturally occurring polysaccharide with β-glycosidic linkages, are widely recognized for their immunomodulatory and therapeutic properties, whereas their inherent properties often restrict their further applications. Sulfated β-glucans have emerged as versatile derivatives of β-glucans with enhanced physicochemical properties, driven by the introduction of sulfate groups onto their backbone. They also exhibit novel or improved bioactivities compared to their unmodified counterparts, owing to their modified molecular structures and strengthened interactions with biological targets. This review summarizes recent advancements in sulfation methods, including the chlorosulfonic acid-pyridine method, sulfur trioxide method, and sulfuric acid method, highlighting their mechanisms, advantages, and limitations. Structural characterization techniques and various biomedical applications are discussed to elucidate the sulfation patterns and provide a theoretical basis for further use and development of sulfated β-glucans. Conclusively, sulfation serves as a promising strategy for fine-tuning β-glucan functionalities and expanding their potential in food and pharmaceutical areas.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"13 ","pages":"Article 101063"},"PeriodicalIF":6.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145791688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0