Carbohydrate Polymer Technologies and Applications最新文献_第10页

Adsorptive removal of toxic heavy metal and dyes from wastewater by rice husk (lignocellulosic biomass) derived activated biochar: A fixed-bed column adsorption study

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-03 DOI: 10.1016/j.carpta.2025.100698

Md. Mahmudur Rahman , Mohd. Maniruzzaman , Nor ealam , Parvej Mahmud , Sumiya Khatun , Md. Kaowsar Hossain , Md. Ismail Hossain , Md. Hasanuzzaman , Md. Ashraful Alam , Md. Al-amin , Bijoy Chandra Ghos

{"title":"Adsorptive removal of toxic heavy metal and dyes from wastewater by rice husk (lignocellulosic biomass) derived activated biochar: A fixed-bed column adsorption study","authors":"Md. Mahmudur Rahman , Mohd. Maniruzzaman , Nor ealam , Parvej Mahmud , Sumiya Khatun , Md. Kaowsar Hossain , Md. Ismail Hossain , Md. Hasanuzzaman , Md. Ashraful Alam , Md. Al-amin , Bijoy Chandra Ghos","doi":"10.1016/j.carpta.2025.100698","DOIUrl":"10.1016/j.carpta.2025.100698","url":null,"abstract":"<div><div>Rapid industrialization/urbanization has been marked as a responsible factor for the creation of bulky effluent which is loaded with several harmful toxicants resulting in a hursh damage to the ecosystem and public safety/secuerity. To mitigate this crucial issue, here a fixed-bed column adsorption technology were chosen due to its simplecity, cost-effectivity, reuseablity. Meanwhile, multifunctional biosorbent <em>i.e</em> functionallized rice husk biochar (FRHBC) was produced by EIPS technique from a beneficial source namely rice(<em>Oriza sativa</em>) waste shell. The experiments were conducted to optimize the effect of influential factors like concentration, flowrates, and bed height. To observe the bulk properties the samples were characterized by FESEM,EDX,BET, FTIR-ATR,XRD, and TGA analysis. The effluents were investigated by AAS and UV–vis-NIR techniques. As per the findings it has been stated that the synthesized FRHBC adsorbents have possessed a promizing 2D honeycomb-like well-oriented mesoporous surface microstructure with a larger surface area around 36.84 m<sup>2</sup>/g. Additionally holds substantial active binding sites, lower crystallinity nearly 23±0.03%, and higher thermal stability upto 700 °C. Noteworthy that the maximum adsorption performence was found 179.77 and 173.01 mg/g for Pb<sup>2+</sup> and MB dye. Hence, the newly produced multifunctional FRHBC bioadsorbents would be benificially used to purify real-time industrial wastewater for sustainable environmental protection.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100698"},"PeriodicalIF":6.2,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insights into selection and application of carbohydrate-based carriers for microencapsulation: Stability and functional properties of maltodextrin, gum Arabic, and β-cyclodextrin in encapsulating tea flower pollen peptides

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-03 DOI: 10.1016/j.carpta.2025.100700

Pegah Mehrali , Seyed Hadi Peighambardoust , Amir Akbarmehr , Khashayar Sarabandi

{"title":"Insights into selection and application of carbohydrate-based carriers for microencapsulation: Stability and functional properties of maltodextrin, gum Arabic, and β-cyclodextrin in encapsulating tea flower pollen peptides","authors":"Pegah Mehrali , Seyed Hadi Peighambardoust , Amir Akbarmehr , Khashayar Sarabandi","doi":"10.1016/j.carpta.2025.100700","DOIUrl":"10.1016/j.carpta.2025.100700","url":null,"abstract":"<div><div>Protein from tea flower pollen (TFP) was extracted and hydrolyzed to achieve polypeptides. The produced peptides were rich in hydrophobic (∼44 %), antioxidants (∼19 %), and essential (∼49 %) amino acids. Various carriers, including maltodextrin (MD), gum Arabic (GA), and β-cyclodextrin (βCD), along with their combinations, were utilized for the encapsulation purpose. The highest spray-drying yield (∼59 %) was achieved when a combination of MD-βCD was used as carrier. The physical characteristics of spray-dried (SD) powders including bulk and tapped densities (packing ability), Hassner ratio, angle of repose and Carr index (powder flowability) were influenced by the type of carriers used. The maximum solubility (88 %) and wettability (333 s) values were obtained for SD-powders produced by MD-GA as carrier. The encapsulation of peptides using MD-βCD caused a significant decrease in the hygroscopicity (from ∼85 to 39 %), indicating their higher physical stability compared to other carriers. The highest antioxidant activity in inhibiting DPPH<sup>−</sup> (∼52.1 %) and ABTS<sup>+</sup> (∼62.5 %) radicals was obtained in peptides stabilized with MD-βCD. Morphological features of SD-powders were affected by the type of carriers. SEM showed that utilizing MD-βCD as carrier leads to formation of spherical particles with smooth surface with less pore formation. FT-IR showed the coverage of amide regions and functional groups of peptides and indicated their placement and distribution within the carrier matrix. This study highlights the potential of using microencapsulated tea flower pollen peptides as a functional ingredient for food and nutraceutical applications.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100700"},"PeriodicalIF":6.2,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143360556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sustainable biopolymer-based spheres for controlled release of nematodes: From development to their effects under seasonal climate variations

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-03 DOI: 10.1016/j.carpta.2025.100701

Javier Pitti Caballero , Rubén Collantes , Débora R. Antunes , Jahzeel Samaniego , Yabelys Santamaría , Jorge Muñoz , Renato Grillo

{"title":"Sustainable biopolymer-based spheres for controlled release of nematodes: From development to their effects under seasonal climate variations","authors":"Javier Pitti Caballero , Rubén Collantes , Débora R. Antunes , Jahzeel Samaniego , Yabelys Santamaría , Jorge Muñoz , Renato Grillo","doi":"10.1016/j.carpta.2025.100701","DOIUrl":"10.1016/j.carpta.2025.100701","url":null,"abstract":"<div><div>The growing challenges of global food security, intensified by climate change and unsustainable agricultural practices, necessitate the development of innovative, environmentally sustainable pest management strategies. This study evaluates the efficacy of alginate- and chitosan-based biopolymer encapsulation systems, augmented with cellulose and encapsulated nematodes (<em>oscheius carolinensis</em>), as viable solutions for sustainable pest control in vegetable cultivation. The formulations were engineered to enable the controlled release of biocontrol agents, optimizing plant growth under varying seasonal climatic conditions (rainy, dry, and transitional seasons). Alginate matrices crosslinked with calcium chloride exhibited significant stability and controlled-release capabilities in the dry season. In contrast, chitosan matrices crosslinked with sodium tripolyphosphate exhibited rapid degradation in the same season. The encapsulation of nematodes favored the degradation of some spheres, while the presence of cellulose reduced their disintegration, prolonging the release of the organisms and reducing their viability in the soil. Tests with lettuce plants showed better development in the rainy season with little variation between treatments. Therefore, this study showed that the influence of environmental factors and the materials used to prepare polymeric spheres interfere with their effect on the soil. These results offer a promising strategy for reducing chemical pesticide reliance, increasing crop yields, and advancing sustainable agricultural practices.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100701"},"PeriodicalIF":6.2,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143351142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Possibility of alleviating dextran sulfate sodium-induced colitis in mice by modulate intestinal barrier function and gut microbiota with laminarin acetyl esters

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-01 DOI: 10.1016/j.carpta.2025.100693

Kit-Leong Cheong , Amanullah Sabir , Suresh Veeraperumal , Franck Quero , Rui Li , Qiaoli Zhao , Karsoon Tan , Saiyi Zhong , Udayakumar Veerabagu

{"title":"Possibility of alleviating dextran sulfate sodium-induced colitis in mice by modulate intestinal barrier function and gut microbiota with laminarin acetyl esters","authors":"Kit-Leong Cheong , Amanullah Sabir , Suresh Veeraperumal , Franck Quero , Rui Li , Qiaoli Zhao , Karsoon Tan , Saiyi Zhong , Udayakumar Veerabagu","doi":"10.1016/j.carpta.2025.100693","DOIUrl":"10.1016/j.carpta.2025.100693","url":null,"abstract":"<div><div>This study investigates the esterification of laminarin, a β-glucan polysaccharide, using trifluoroacetic anhydride and acetic acid to synthesize laminarin acetyl esters (LA) with potential therapeutic properties. The efficacy of LA was evaluated in an <em>in vivo</em> dextran sulfate sodium induced colitis mouse model. Treatment with LA significantly improved the organ index and modulated inflammatory responses by upregulating anti-inflammatory cytokines, such as IL-10 and TGF-β1. LA also promoted a favorable shift in gut microbiota composition, notably increasing the relative abundance of beneficial bacteria like <em>Lactobacillus</em> and <em>Bifidobacterium</em>, and enhancing short-chain fatty acid production, particularly acetic acid. Immunohistochemical analysis revealed a reduction in CD68 expression and an elevation in CD163 expression, indicating a shift toward an anti-inflammatory macrophage phenotype. These findings demonstrate that LA mitigates pro-inflammatory responses, enhances gut barrier integrity, and supports a healthy gut microbiota, underscoring its potential as a therapeutic agent for managing colitis and improving gut health.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100693"},"PeriodicalIF":6.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143360557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chitosan suitability to adhesion, neuronal differentiation and maturation of hiPSCs compared to Matrigel coated substrates

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-02-01 DOI: 10.1016/j.carpta.2025.100686

Sara Grasselli , Donatella Di Lisa , Pier Francesco Ferrari , Sergio Martinoia , Laura Pastorino

{"title":"Chitosan suitability to adhesion, neuronal differentiation and maturation of hiPSCs compared to Matrigel coated substrates","authors":"Sara Grasselli , Donatella Di Lisa , Pier Francesco Ferrari , Sergio Martinoia , Laura Pastorino","doi":"10.1016/j.carpta.2025.100686","DOIUrl":"10.1016/j.carpta.2025.100686","url":null,"abstract":"<div><div>Human induced pluripotent stem cells (hiPSCs) derived neurons are revolutionising the study of patient-specific conditions. Typically, hiPSCs are expanded and differentiated onto Matrigel. However, to obtain a functional network, early-stage neurons are transferred to laminin/polyornithine (PORN/LAM) coated substrates, undergoing great stress that may hinder the complete network development. Finding an adhesion factor that supports the differentiation and maturation of the neural networks of hiPSCs derived neurons is therefore crucial. The ability of chitosan (CHI) in supporting the adhesion and development of functional neuronal networks has already been demonstrated for iNeurons, indicating CHI as an alternative to PORN/LAM.</div><div>In this study, we investigated the bioactivity of CHI by comparing its ability to support the early-stage differentiation of hiPSCs to that of Matrigel. To this aim, cell adhesion, survival and differentiation was monitored over 14 days of culture both on culture supports functionalized with Matrigel and CHI. Cell differentiation was investigated <em>via</em> immunocytochemistry and western blot analysis. Stemness markers and neuronal markers were used to confirm the gradual differentiation of cells. Moreover, the early-stage differentiation was carried out onto CHI coated micro-electrode arrays in co-culture with primary astrocytes followed by the complete maturation of the neuronal network as demonstrated by recorded spontaneous electrophysiological activity.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100686"},"PeriodicalIF":6.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143348395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spray drying of saffron extract-loaded coacervates by carboxymethyl cellulose/maltodextrin/saffron petal anthocyanins

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-01-30 DOI: 10.1016/j.carpta.2025.100690

Hamid Rajabi , Samineh Sedaghati , Hamidreza Farajnezhad , Seid Mahdi Jafari

{"title":"Spray drying of saffron extract-loaded coacervates by carboxymethyl cellulose/maltodextrin/saffron petal anthocyanins","authors":"Hamid Rajabi , Samineh Sedaghati , Hamidreza Farajnezhad , Seid Mahdi Jafari","doi":"10.1016/j.carpta.2025.100690","DOIUrl":"10.1016/j.carpta.2025.100690","url":null,"abstract":"<div><div>An active/dual encapsulation system was designed to enhance the stability of saffron bioactive compounds (SBCs) by incorporating saffron petal extract (SPE) as a natural antioxidant into the wall material. SBCs were encapsulated using complex coacervation of pectin (PE) and gelatin (GE), followed by spray drying (SD) with maltodextrin (MD, 15–25 g/100 mL), carboxymethyl cellulose (CMC, 0–2 g/100 mL), and SPE (0–10 mg/100 mL) as wall materials. X-ray diffraction confirmed the amorphous regions within the coacervates, indicating the formation of electrostatic interactions and hydrogen bonds. The concentration of SBCs significantly affected the polydispersity index (0.28–0.59), particle size (295–503 nm), and encapsulation efficiency (58.62–89.19%) of the coacervates. Spray-dried coacervates exhibited yields (60.23–91.20%) and encapsulation efficiencies (62.19–93.73%), both dependent on the formulation. Fourier transform infrared analysis confirmed the effective coverage of SPE by the wall materials. Stability tests showed that crocin retention was significantly enhanced by approximately 11% in the active encapsulation system (15MD/0CMC/10SPE) compared to the conventional system (23MD/2CMC/0SPE). Our findings demonstrate that this active/dual encapsulation system significantly improved the retention of SBCs, suggesting its potential use for safeguarding other bioactive components.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100690"},"PeriodicalIF":6.2,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143098814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In situ delivery of synthetic preimplantation factor using aldehyde-modified hyaluronic acid hydrogel with immobilized complexes of chondroitin sulfate derivatives

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-01-28 DOI: 10.1016/j.carpta.2025.100689

Tutut Habibah , Andrea Exnerová , Kristina Nešporová , Una FitzGerald , Abhay Pandit , Marek Ingr , Martin Pravda , Vladimír Velebný

{"title":"In situ delivery of synthetic preimplantation factor using aldehyde-modified hyaluronic acid hydrogel with immobilized complexes of chondroitin sulfate derivatives","authors":"Tutut Habibah , Andrea Exnerová , Kristina Nešporová , Una FitzGerald , Abhay Pandit , Marek Ingr , Martin Pravda , Vladimír Velebný","doi":"10.1016/j.carpta.2025.100689","DOIUrl":"10.1016/j.carpta.2025.100689","url":null,"abstract":"<div><div>Synthetic preimplantation factor (SPIF) is a promising therapeutic agent for chronic inflammatory diseases like Multiple Sclerosis (MS), but frequent systemic dosing limits patient adherence and therapy efficacy. This study presents an injectable drug delivery system (DDS) using 2 % (w/v) aldehyde-modified hyaluronic acid (HAOX) and chondroitin sulfate (CSOX) to deliver 100 µg of Fluorescein isothiocyanate-modified SPIF (FITC-SPIF). The DDS utilizes electrostatic interactions between the negatively charged sulfate groups of CSOX and the positively charged amino acids of FITC-SPIF for effective entrapment. Key properties were analyzed, including moderate gelation time (193 s), swelling profile (18 %), injectability (27 G needle) and an established relevant release profile (20 μg/daily <span><math><mo>±</mo></math></span> 3) via anomalous diffusion. Increasing CSOX concentration reduced initial burst release by 38 % (0.5 % CSOX) to 78 % (1 % CSOX), extending release time (T50 %) from 50 h (0.5 % CSOX) to 88 h (1 % CSOX). Additionally, the release of FITC-SPIF enhanced TGF-β secretion in THP-1 macrophages, indicating preserved biological activity. These findings highlight the tunable release and mechanical properties achieved by adjusting the HAOX:CSOX ratio, strategically aligning the DDS for targeted MS symptom management. This system potentially simplifies SPIF delivery and enhances therapeutic efficacy.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100689"},"PeriodicalIF":6.2,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143098816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation between gastrointestinal index (GI) and the structure and physicochemical properties of rice starch from different varieties and colors

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-01-27 DOI: 10.1016/j.carpta.2025.100687

Ming Wu, Chenchen Wu, Yizhu Wang, Xin Bian, Dong Liang, Guang Zhang, Xiaofei Liu, Na Zhang

{"title":"Correlation between gastrointestinal index (GI) and the structure and physicochemical properties of rice starch from different varieties and colors","authors":"Ming Wu, Chenchen Wu, Yizhu Wang, Xin Bian, Dong Liang, Guang Zhang, Xiaofei Liu, Na Zhang","doi":"10.1016/j.carpta.2025.100687","DOIUrl":"10.1016/j.carpta.2025.100687","url":null,"abstract":"<div><div>Rice contains a high level of starch, which is quickly digested and results in a high Glycaemic Index (GI) in vivo. The GI value is closely related to the proportion, structure, and physicochemical properties of the intrinsic starch. Understanding these relationships can help optimize diet and select foods with low GI values, resulting in better blood glucose management. This research examined the effects and physicochemical characteristics of starch obtained from 12 native rice germplasms sourced from different areas of China, analyzing their consistency and relevance through various categorized methods. The results showed that the polished round-grained colored rice from Suihua, Heilongjiang Province, and the glutinous white rice from Ningbo, Zhejiang Province, exhibited the lowest and highest GI values, respectively. Additionally, colored rice had a lower GI value compared to white rice of the same type.</div><div>The results of correlation analysis showed that the starch content, composition and crystallinity of rice were the main factors affecting the GI value of rice. The outcomes of this research may aid in optimizing the application of rice starch in both food and non-food sectors.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100687"},"PeriodicalIF":6.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143098040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A thermo-responsive chitosan-based injectable hydrogel for delivery of curcumin-loaded polycaprolactone microspheres to articular cartilage: in-vitro and in-vivo assessments

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-01-26 DOI: 10.1016/j.carpta.2025.100678

Farnoosh Kalantarnia , Sasan Maleki , Amir Shamloo , Kazem Akbarnataj , Sayed Navid Tavoosi

{"title":"A thermo-responsive chitosan-based injectable hydrogel for delivery of curcumin-loaded polycaprolactone microspheres to articular cartilage: in-vitro and in-vivo assessments","authors":"Farnoosh Kalantarnia , Sasan Maleki , Amir Shamloo , Kazem Akbarnataj , Sayed Navid Tavoosi","doi":"10.1016/j.carpta.2025.100678","DOIUrl":"10.1016/j.carpta.2025.100678","url":null,"abstract":"<div><div>Articular cartilage has limited regenerative capacity, posing a significant challenge in healing cartilage-related disorders. While injectable hydrogels have shown potential as a treatment, achieving an optimal balance between bio-compatibility, mechanical properties, and drug delivery remains a challenge. This study developed a chitosan-based injectable hydrogel reinforced with bacterial cellulose nanofibers to enhance mechanical stability and biological functionality. The hydrogel exhibited great porosity (∼57.96 %) with a mean pore diameter of ∼104.30 <em>µm</em>, and a compressive modulus of ∼4.65 kPa, offering an encouraging micro-environment for cell proliferation and tissue regeneration. The degradation rate of ∼55 % over 30 days was tailored to match the timeline of cartilage repair. Additionally, polycaprolactone microspheres, prepared by solid/oil/water method, were used to enhance the bio-availability of curcumin and its sustained delivery. The hydrogel system containing drug-loaded microspheres showed ∼23.55 % drug released by day 7. Moreover, anti-bacterial assays confirmed the hydrogel's effectiveness against <em>S. aureus</em> and <em>E. coli</em>. Also, bio-compatibility assessments showed high fibroblast viability over 7 days. <em>In-vivo</em> evaluations on rabbit models indicated significant cartilage regeneration, evidenced by improved locomotion behavior and accelerated cartilage formation with minimized defect boundaries. Similarly, histological analysis revealed enhanced chondrocyte density compared to the control group. These findings highlight the synergistic role of scaffold composition, mechanical properties, and controlled drug delivery in promoting cartilage regeneration, underscoring the potential clinical applications of this multifaceted hydrogel for cartilage repair.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100678"},"PeriodicalIF":6.2,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143098818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Encapsulation of albumin from snakehead fish (Channa striata) with porous starch from arrowroot (Maranta arundinacea)

IF 6.2

Carbohydrate Polymer Technologies and Applications Pub Date : 2025-01-25 DOI: 10.1016/j.carpta.2025.100684

Nastitia Dian Pratiwi, Arima Diah Setiowati, Lucia Dhiantika Witasari

{"title":"Encapsulation of albumin from snakehead fish (Channa striata) with porous starch from arrowroot (Maranta arundinacea)","authors":"Nastitia Dian Pratiwi, Arima Diah Setiowati, Lucia Dhiantika Witasari","doi":"10.1016/j.carpta.2025.100684","DOIUrl":"10.1016/j.carpta.2025.100684","url":null,"abstract":"<div><div>Through an enzymatic process, arrowroot (<em>Maranta arundinacea</em>) porous starch produces pores on the surface of starch granules, making it a potential bioadsorbent and encapsulation material. Snakehead fish albumin (<em>Channa striata</em>) is a sensitive component whose functional properties must be preserved. Therefore, encapsulating albumin through spray drying is necessary to protect it from external environmental factors. This study aimed to evaluate the encapsulation efficiency as well as morphological, physical, and chemical properties of encapsulated albumin using arrowroot porous starch. The P-50, porous starch:gum arabic (50:50) formula demonstrated the highest encapsulation efficiency of 98.88 %. Scanning electron microscopy revealed that porous starch adsorbs albumin on its surface. X-ray diffraction and Fourier-transform infrared profiles indicated an amorphous structure with minimal crystallinity, confirming the adsorption of albumin onto porous starch. The water content and water activity values of powder encapsulated with porous starch were better than those of native starch. Therefore, porous starch from arrowroot can be effectively used as an albumin encapsulant.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"9 ","pages":"Article 100684"},"PeriodicalIF":6.2,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143098815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0