Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects最新文献_第9页

Synthetic pyrimidines as inhibitors of uracil and thymine degradation by rat-liver supernatant 大鼠肝脏上清液降解尿嘧啶和胸腺嘧啶的合成嘧啶抑制剂

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90242-7

Harold W. Barrett , S.N. Munavalli , Philip Newmark

引用次数: 26

Phosphorylation of thymidine diphosphate in resting and proliferating mammalian cells 静止和增殖的哺乳动物细胞中胸腺二磷酸的磷酸化

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90256-7

P.A. Bianchi, M.V. Farina, E. Polli

引用次数: 13

Ribosomes and polyribosomes in Brassica pekinensis 北京芸苔的核糖体和多核糖体

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90253-1

M.F. Clark, R.E.F. Matthews, R.K. Ralph

引用次数: 88

Characteristics of the inhibition of hemoglobin synthesis in rabbit reticulocytes by threo-α-amino-β-chlorobutyric acid 三-α-氨基-β-氯丁酸抑制兔网织红细胞血红蛋白合成的特性

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90255-5

M. Rabinovitz, J.M. Fisher

{"title":"Characteristics of the inhibition of hemoglobin synthesis in rabbit reticulocytes by threo-α-amino-β-chlorobutyric acid","authors":"M. Rabinovitz, J.M. Fisher","doi":"10.1016/0926-6550(64)90255-5","DOIUrl":"10.1016/0926-6550(64)90255-5","url":null,"abstract":"<div><ul><li>1.1. Addition of the valine antagonist, α-amino-β-chlorobutyric acid, to rabbit reticulocytes produces a rapid inhibition of hemoglobin synthesis with a subsequent increase in labelling of protein of the ribosomal fraction.</li><li>2.2. At appropriate antagonist: valine ratios, the incorporation of valine itself occurs at the ribosomal level, but is inhibited in hemoglobin. This indicates that the block in hemoglobin synthesis is caused by substitution of the analogue for valine at specific valine sites, and it is suggested that the loci of these substitutions may be the Val-Val residues on the precursor protein of the β-chain.</li><li>3.3. The antagonist also inhibits [14C]isoleucine incorporation into hemoglobin, but unlike other amino acids, isoleucine does not accumulate in protein of the ribosomal fraction. This observation is discussed in relation to the characteristics of isoleucine incorporation into reticulocyte proteins and the location of residues of this amino acid near the NH2-terminal end of the α-chain of rabbit hemoglobin.</li><li>4.4. Synthesis of both the α- and β-chains of hemoglobin is blocked by the antagonist and there is no evidence for the preferential synthesis and release of either chain.</li><li>5.5. Abortive protein formed in the presence of the antagonist is rapidly degraded into trichloroaceeric acid-soluble products.</li></ul></div>","PeriodicalId":100173,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects","volume":"91 2","pages":"Pages 313-322"},"PeriodicalIF":0.0,"publicationDate":"1964-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6550(64)90255-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23789604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 81

Biosynthesis of co-polymers of uridylic and cytidylic acids with 6-azacytidylic acid 尿苷酸和胞苷酸与6-氮杂胞苷酸共聚物的生物合成

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90267-1

J. Škoda, F. Šorm

引用次数: 3

On the lack of a uniform specificity of aminoacyl ribonucleic acid synthetases from different organisms 关于来自不同生物体的氨基酸核糖核酸合成酶缺乏统一的特异性

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90254-3

K. Bruce Jacobson, S. Nishimura , W.Edgar Barnett, Rusty J. Mans , P. Cammarano , G. David Novelli

引用次数: 21

Uptake of [14C]formate by bone marrow and spleen nucleic acids in normal and erythrocyte-transfused mice 正常和红细胞输注小鼠骨髓和脾脏核酸对[14C]甲酸的摄取

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90261-0

Marco Perretta , Wilhelm Rudolph , Gloria Aguirre , George Hodgson

引用次数: 1

Picture of Professor H.G.K. Westenbrink H.G.K. Westenbrink教授的照片

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90240-3

引用次数: 0

Studies on the mechanism of methylcholanthrene induction of enzyme activities 甲基胆蒽诱导酶活性的机制研究

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-09-11 DOI: 10.1016/0926-6550(64)90177-X

Harry V. Gelboin

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引用次数: 54

Biosynthesis of a new uric acid ribonucleotide 一种新的尿酸核糖核苷酸的生物合成

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-09-11 DOI: 10.1016/0926-6550(64)90182-3

Dolph Hatfield, Roy A. Greenland, H.L. Stewart, James B. Wyngaarden

引用次数: 7