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Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects最新文献

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Factors effecting the chain-length of fatty acids synthesized by lactating-rabbit mammary glands 影响泌乳兔乳腺合成脂肪酸链长的因素
Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects Pub Date : 1964-12-02 DOI: 10.1016/0926-6542(64)90044-7
S. Smith, R. Dils
{"title":"Factors effecting the chain-length of fatty acids synthesized by lactating-rabbit mammary glands","authors":"S. Smith, R. Dils","doi":"10.1016/0926-6542(64)90044-7","DOIUrl":"10.1016/0926-6542(64)90044-7","url":null,"abstract":"","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1964-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90044-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23818461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 53
Characterization of lipovitellenin components, and their relation to low-density liproprotein structure 脂卵黄素成分的表征及其与低密度脂蛋白结构的关系
Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects Pub Date : 1964-12-02 DOI: 10.1016/0926-6542(64)90030-7
J. Augustyniak, W.G. Martin, W.H. Cook
{"title":"Characterization of lipovitellenin components, and their relation to low-density liproprotein structure","authors":"J. Augustyniak,&nbsp;W.G. Martin,&nbsp;W.H. Cook","doi":"10.1016/0926-6542(64)90030-7","DOIUrl":"10.1016/0926-6542(64)90030-7","url":null,"abstract":"<div><p>When aqueous solutions of the LDF of egg yolk and its fractions LDF<sub>1</sub> and LDF<sub>2</sub> were extracted with ethyl ether, all yielded five derived components having sedimentation rates of about 4 S, 7 S, 13 S, 15 S and 17 S. The first three of these were isolated and had molecular weights of 2.9·10<sup>5</sup>, 11·10<sup>5</sup> and 13·10<sup>5</sup>, and lipid contents of 50, 67 and 44%, respectively. These components were formed sequentially in the order 7 S → 4 S → 13 S and hence all contain the same proteins, although different combinations of polypeptide chains may be present. Apparently a reduction in lipid content below 50% causes an aggregation of 4-S particles to form 13 S and other rapidly sedimenting products. The sizes of the protein moieties, computed from the molecular weight and lipid content of the native fractions LDF<sub>1</sub> and LDF<sub>2</sub> and the derived products 7 S and 4 S, are in the order 8, 4, 2 and 1, respectively, with the smallest unit size estimated to be (1.7 ± 0.16) ·10<sup>5</sup>. Evidently the size of the protein moiety decreases stepwise as the lipid content decreases down to 4 S and this behavior, plus aggregation at low lipid contents, yields detectable and separable components in both the natural and derived from of these lipoproteins.</p></div>","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1964-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90030-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23819456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Identication of prostaglandin F3α in bovine lung 牛肺组织中前列腺素F3α的鉴定
Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects Pub Date : 1964-12-02 DOI: 10.1016/0926-6542(64)90028-9
Bengt Samuelson
{"title":"Identication of prostaglandin F3α in bovine lung","authors":"Bengt Samuelson","doi":"10.1016/0926-6542(64)90028-9","DOIUrl":"10.1016/0926-6542(64)90028-9","url":null,"abstract":"<div><p>Prostaglandin F<sub>3α</sub> was isolatd from bovine lung by reversed-phase partition chromatography, silicic acid chromatography and thin-layer chromatography. Final identification was achieved by gas-liquid chromatography of a trimethylsilyl ether derivative, infrared spectroscopy and mass spectropgraphic analysis. The stereo-chemistry at C-9 was determined by an isotope technique.</p><p>Prostaglandin F<sub>2α</sub>, earlier isolated from lung tissue of other species, was also identified.</p></div>","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1964-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90028-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73397595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Metabolic products of α-tocopherol in the livers of rats given intraperitoneal injections of [14C]-α-tocopherol 腹腔注射[14C]-α-生育酚大鼠肝脏代谢产物的研究
Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects Pub Date : 1964-12-02 DOI: 10.1016/0926-6542(64)90031-9
P.A. Plack , J.G. Bieri
{"title":"Metabolic products of α-tocopherol in the livers of rats given intraperitoneal injections of [14C]-α-tocopherol","authors":"P.A. Plack ,&nbsp;J.G. Bieri","doi":"10.1016/0926-6542(64)90031-9","DOIUrl":"10.1016/0926-6542(64)90031-9","url":null,"abstract":"<div><p>Rats fed a vitamin E-deficient diet for 1–5 months were given intraperitoneal injections of 1 mg [<sup>14</sup>C]-α-tocopherol. After 48 h thye were killed and their lives removed and analyzed by thin-layer and column chromatography for α-tocopherol and metabolic products. Of the recovered radioactivity, about 80% was in the form of uncahnged α-tocopherol and 11% was present as a more polar compound, probably α-tocopherylquinone. No definitive evidence was obtained for the presence of a dimer. Control experiments showed that chromatography of α-tocopherol on thin-layer plates, with aqueous acetonitrile, gave rise to considerable amounts of polar material.</p></div>","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1964-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90031-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23818448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Distribution ldinsaturés-insaturés” des acides gras dans les triglycérides élaïdisés du rat 大鼠脂甘油三酯中脂肪酸的ldin饱和-不饱和分布
Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects Pub Date : 1964-12-02 DOI: 10.1016/0926-6542(64)90033-2
J. Raulin, J. Clement
{"title":"Distribution ldinsaturés-insaturés” des acides gras dans les triglycérides élaïdisés du rat","authors":"J. Raulin,&nbsp;J. Clement","doi":"10.1016/0926-6542(64)90033-2","DOIUrl":"10.1016/0926-6542(64)90033-2","url":null,"abstract":"","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1964-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90033-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78833406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Myo-inositol phosphates in a phosphoinositide complex from kidney 肌醇磷酸是来自肾脏的磷酸肌醇复合物
Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects Pub Date : 1964-12-02 DOI: 10.1016/0926-6542(64)90026-5
F. Andrade, C.G. Huggins
{"title":"Myo-inositol phosphates in a phosphoinositide complex from kidney","authors":"F. Andrade,&nbsp;C.G. Huggins","doi":"10.1016/0926-6542(64)90026-5","DOIUrl":"10.1016/0926-6542(64)90026-5","url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. Chemical studies on the “phosphatido-peptide fraction” from kidney have shown that this material more properly should be called a phosphoinositide complex.</p></span></li><li><span>2.</span><span><p>2. Glycerophosphate, inositol mono-, di- and triphosphate were separated from alkaline hydrolysates by means of paper chromatography.</p></span></li><li><span>3.</span><span><p>3. Six fractions were obtained by column chromatography from the deacylated phosphoinositide complex and identified as inositol monophosphate, glycerophosphate, inositol diphosphate, glycerylphosphoryl inositol, glycerylphosphoryl inositol phosphate, and glycerylphosphoryl inositol diphosphate.</p></span></li><li><span>4.</span><span><p>4. These phosphates, presumably as the inositides, are believed to be responsible for the hgh metabolic activity of this fraction as measured by radiophosphorus.</p></span></li></ul></div>","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1964-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90026-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23818444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
Identification of ceramide monohexoside and ceramide dihexoside in bovine milk 牛乳中神经酰胺单己糖和神经酰胺二己糖的鉴定
Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects Pub Date : 1964-12-02 DOI: 10.1016/0926-6542(64)90037-X
William R. Morrison , Lloyd M. Smith
{"title":"Identification of ceramide monohexoside and ceramide dihexoside in bovine milk","authors":"William R. Morrison ,&nbsp;Lloyd M. Smith","doi":"10.1016/0926-6542(64)90037-X","DOIUrl":"10.1016/0926-6542(64)90037-X","url":null,"abstract":"","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1964-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90037-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23818454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 22
Studies of the composition and structure of serum lipoproteins: Physical-chemical characterization of phospholipid-protein residues obtained from very-low-density human serum lipoproteins 血清脂蛋白组成和结构的研究:从极低密度人血清脂蛋白中获得的磷脂蛋白残基的物理化学表征
Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects Pub Date : 1964-12-02 DOI: 10.1016/0926-6542(64)90040-X
A. Gustafson , P. Alaupovic , R.H. Furman
{"title":"Studies of the composition and structure of serum lipoproteins: Physical-chemical characterization of phospholipid-protein residues obtained from very-low-density human serum lipoproteins","authors":"A. Gustafson ,&nbsp;P. Alaupovic ,&nbsp;R.H. Furman","doi":"10.1016/0926-6542(64)90040-X","DOIUrl":"10.1016/0926-6542(64)90040-X","url":null,"abstract":"","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1964-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90040-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23818457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 50
Fatty acid composition of the lipids of membranes of gram-positive bacteria and “walls” of gram-negative bacteria 革兰氏阳性菌膜脂质和革兰氏阴性菌“壁”的脂肪酸组成
Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects Pub Date : 1964-12-02 DOI: 10.1016/0926-6542(64)90043-5
K.Y. Cho, M.R.J. Salton
{"title":"Fatty acid composition of the lipids of membranes of gram-positive bacteria and “walls” of gram-negative bacteria","authors":"K.Y. Cho,&nbsp;M.R.J. Salton","doi":"10.1016/0926-6542(64)90043-5","DOIUrl":"10.1016/0926-6542(64)90043-5","url":null,"abstract":"","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1964-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90043-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23818460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Effect of puromycin on incubated adipose tissue and its response to dexamethasone, insulin, and epinephrine 嘌呤霉素对培养脂肪组织的影响及其对地塞米松、胰岛素和肾上腺素的反应
Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects Pub Date : 1964-12-02 DOI: 10.1016/0926-6542(64)90023-X
John N. Fain
{"title":"Effect of puromycin on incubated adipose tissue and its response to dexamethasone, insulin, and epinephrine","authors":"John N. Fain","doi":"10.1016/0926-6542(64)90023-X","DOIUrl":"10.1016/0926-6542(64)90023-X","url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. Puromycin (10<sup>−4</sup> M), puromycin aminonucleoside (10<sup>−4</sup> M) and dexamethasone (4·10<sup>−8</sup> M) decreased the uptake and conversion of glucose to CO<sub>2</sub>, glyceride-glycerol and fatty acid by incubated rat-adipose tissue. These substances had little effect on the metabolism of fructose or pyruvate by adipose tissue. Puromycin blocked or decreased the incorporation of glucose, fructose, and pyruvate carbon into protein; aminonucleoside and dexamethasone had little effect.</p></span></li><li><span>2.</span><span><p>2. Puromycin blocked the stimulation of protein synthesis by insulin but did not alter the other actions of insulin or the effects of dexamethasone and epinephrine on adipose tissue.</p></span></li><li><span>3.</span><span><p>3. Insulin decreased the conversion of pyruvate to lactate and increased its conversion to fatty acid in the presence and the absence of puromycin.</p></span></li></ul></div>","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1964-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90023-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23814923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
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