肌醇磷酸是来自肾脏的磷酸肌醇复合物

F. Andrade, C.G. Huggins
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引用次数: 19

摘要

1.1. 对肾中“磷脂肽组分”的化学研究表明,这种物质更恰当地称为磷酸肌肽复合物。用纸层析法从碱性水解物中分离出甘油磷酸、肌醇单磷酸、二磷酸和三磷酸。通过柱层析得到脱酰基磷酸肌醇复合物的6个组分,分别鉴定为单磷酸肌醇、甘油磷酸、二磷酸肌醇、甘油磷酸肌醇、甘油磷酸肌醇磷酸和甘油磷酸肌醇二磷酸。这些磷酸盐,据推测是肌内酯,被认为是由放射性磷测量的这部分高代谢活性的原因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Myo-inositol phosphates in a phosphoinositide complex from kidney

  • 1.

    1. Chemical studies on the “phosphatido-peptide fraction” from kidney have shown that this material more properly should be called a phosphoinositide complex.

  • 2.

    2. Glycerophosphate, inositol mono-, di- and triphosphate were separated from alkaline hydrolysates by means of paper chromatography.

  • 3.

    3. Six fractions were obtained by column chromatography from the deacylated phosphoinositide complex and identified as inositol monophosphate, glycerophosphate, inositol diphosphate, glycerylphosphoryl inositol, glycerylphosphoryl inositol phosphate, and glycerylphosphoryl inositol diphosphate.

  • 4.

    4. These phosphates, presumably as the inositides, are believed to be responsible for the hgh metabolic activity of this fraction as measured by radiophosphorus.

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