Advanced Sensor and Energy Materials最新文献_第3页

Aptamer-based biosensors for biogenic amines detection 基于适配体的生物胺检测传感器

Advanced Sensor and Energy Materials Pub Date : 2025-06-01 Epub Date: 2025-01-18 DOI: 10.1016/j.asems.2025.100135

Min Yang , Yushi Xie , Longjiao Zhu , Ran Wang , Jie Zheng , Wentao Xu

{"title":"Aptamer-based biosensors for biogenic amines detection","authors":"Min Yang , Yushi Xie , Longjiao Zhu , Ran Wang , Jie Zheng , Wentao Xu","doi":"10.1016/j.asems.2025.100135","DOIUrl":"10.1016/j.asems.2025.100135","url":null,"abstract":"<div><div>Biogenic amines (BAs) are a class of small nitrogen-containing organic compounds commonly found in various foods and are one of the common metabolic by-products in the process of food spoilage. When consumed in excessive amounts by the human body, BAs can cause a range of adverse reactions such as difficulty in breathing and palpitations, posing a serious threat to life and health. Moreover, the content of BAs is closely related to the degree of food spoilage, making them an important indicator for measuring food quality and freshness. Therefore, accurate detection of BAs is particularly important. Aptamer biosensors are becoming more and more important in the field of biosensing and show great potential. In this review, we first systematically summarized the structural characteristics, formation mechanism and potential toxicity of BAs. Then, the screening strategies and methods of biogenic amine aptamers were discussed. On this basis, we focus on the latest progress in the field of aptamer sensor technology for BAs detection in food and divide these technologies into four categories according to the detection principle: colorimetric analysis, fluorescence detection, surface-enhanced Raman spectroscopy (SERS) analysis and electrochemical detection. Finally, the future development direction and current challenges of biogenic amine detection strategies are introduced.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 2","pages":"Article 100135"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143600909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial: Recent approaches in biosensors and wearable sensors 社论：生物传感器和可穿戴传感器的最新进展

Advanced Sensor and Energy Materials Pub Date : 2025-06-01 Epub Date: 2025-03-01 DOI: 10.1016/j.asems.2025.100143

Chengyi Xiong

引用次数: 0

Metal-bearing nanomaterials for oral antibacteria: Mechanisms and applications 含金属纳米口腔抗菌材料：机理与应用

Advanced Sensor and Energy Materials Pub Date : 2025-06-01 Epub Date: 2025-03-03 DOI: 10.1016/j.asems.2025.100141

Ke Quan , Yuqing Zeng , Sijia Gao , Yanli Lei , Le Yang , Yibo Zhou , Lucky Poh Wah Goh , Zhihe Qing

{"title":"Metal-bearing nanomaterials for oral antibacteria: Mechanisms and applications","authors":"Ke Quan , Yuqing Zeng , Sijia Gao , Yanli Lei , Le Yang , Yibo Zhou , Lucky Poh Wah Goh , Zhihe Qing","doi":"10.1016/j.asems.2025.100141","DOIUrl":"10.1016/j.asems.2025.100141","url":null,"abstract":"<div><div>The prevalent oral diseases, such as dental caries, chronic gingivitis, and periodontitis, which are primarily caused by pathogenic bacteria, pose significant public health risks and impose substantial economic burdens. However, conventional treatment strategies for oral pathogens rely on mechanical debridement and antibiotic treatment, which remain unsatisfactory and contribute to the emergence of antimicrobial resistance pathogens. The escalating crisis of antibiotic resistance and the intricate microbial communities in oral niches urgently demand innovative antimicrobial strategies that can overcome these issues. Metal-bearing nanomaterials (MBNs), as an integration of metallic components with other substances such as polymers or inorganic materials, have demonstrated improved antimicrobial effectiveness while mitigating the toxicity associated with pure metals in oral environments. This review provides an innovative overview of designing and utilizing MBNs for oral antimicrobial applications, bridging the gap between nanomaterial design and clinical dentistry needs while guiding the development of next-generation antimicrobials in the post-antibiotic era. Firstly, we categorize and elucidate the main antibacterial mechanisms of metallic components in MBNs. Furthermore, a comprehensive summary is provided on the up-to-date advancements in using MBNs for oral antibacterial purposes, highlighting the pivotal role of metals in enhancing antibacterial properties. Finally, we discuss the existing challenges and potential future developments to establish a theoretical foundation for ongoing progress and clinical approval.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 2","pages":"Article 100141"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wearable electrochemical sensor for real-time sweat monitoring powered by Li–S battery: Rapid ion-electron transduction driven by high-entropy Prussian blue analogues 用于实时汗液监测的可穿戴电化学传感器，由锂-S 电池供电：高熵普鲁士蓝类似物驱动的快速离子-电子转换

Advanced Sensor and Energy Materials Pub Date : 2025-06-01 Epub Date: 2025-03-18 DOI: 10.1016/j.asems.2025.100150

Zhong-Hui Sun , Qiu-Ling Huang , Zhan-Chao Li , Wei Zheng , Yan Mao , Dong-Xue Han , Gang Huang

{"title":"Wearable electrochemical sensor for real-time sweat monitoring powered by Li–S battery: Rapid ion-electron transduction driven by high-entropy Prussian blue analogues","authors":"Zhong-Hui Sun , Qiu-Ling Huang , Zhan-Chao Li , Wei Zheng , Yan Mao , Dong-Xue Han , Gang Huang","doi":"10.1016/j.asems.2025.100150","DOIUrl":"10.1016/j.asems.2025.100150","url":null,"abstract":"<div><div>The portable electrochemical sensors couple with high-energy density batteries lay the foundation for intelligent electronic devices capable of real-time and long-term monitoring of signals at the molecular level. Currently, high-entropy materials play a crucial role in advanced energy storage system and electroanalytical chemistry due to their powerful multi active centers and lattice strain fields. Herein, we propose high-entropy Prussian blue analogues (HE-PBA) as a bidirectional catalyst to reduce the activation energy of sulfur redox reaction, alleviate polysulfides shuttle, and inhibit lithium dendritic growth in Li–S battery. Furthermore, benefited from hierarchical HE-PBA with multiple redox active sites, superior ion-selective effect, high ionic/electrical conductivity and hydrophobicity, thus contributing to splendid ion-electron transducer capability as solid contact layer in wearable potentiometric electrochemical sensors. As a result, an advanced wearable electronic device integrates LSB as a power source with potentiometric electrochemical sensor unit equipped with ion selective electrode, enabling real-time monitoring of K<sup>+</sup> concentration in sweat metabolite during outdoor exercise. In a word, this work demonstrates a tremendous potential of designing multifunctional electrode materials for advanced energy storage and electrochemical sensing applications through high entropy strategies.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 2","pages":"Article 100150"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143828520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Palladium–iridium nanocubes modified with a high-affinity DNA aptamer as paired viral diagnostic and therapeutic tools 高亲和力DNA适体修饰的钯铱纳米立方作为配对病毒诊断和治疗工具

Advanced Sensor and Energy Materials Pub Date : 2025-06-01 Epub Date: 2024-10-30 DOI: 10.1016/j.asems.2024.100125

Rudi Liu , Jiuxing Li , Jimmy Gu , Bruno J. Salena , Yingfu Li

{"title":"Palladium–iridium nanocubes modified with a high-affinity DNA aptamer as paired viral diagnostic and therapeutic tools","authors":"Rudi Liu , Jiuxing Li , Jimmy Gu , Bruno J. Salena , Yingfu Li","doi":"10.1016/j.asems.2024.100125","DOIUrl":"10.1016/j.asems.2024.100125","url":null,"abstract":"<div><div>The COVID-19 pandemic emphasizes the need for the development of molecular tools that can be used as effective diagnostic and therapeutic agents. Herein we investigate the potential of aptamer-dressed nanomaterials both as diagnostics and therapeutics using SARS-CoV-2 as a model. The nanomaterials are based on the palladium-iridium (Pd–Ir) nanocubes modified with monomeric, dimeric or trimeric aptamers that exhibit varying affinities for the spike protein of SARS-CoV-2. These nanomaterials were first examined for diagnostic potential through the creation of a nanozyme-linked aptamer assay (NLAA) that takes advantage of the peroxidase-mimicking activity of Pd–Ir nanocubes. The trimeric aptamer-based NLAA demonstrated a limit of detection (LOD) of 9.3×10<sup>3</sup> cp/mL for pseudoviruses expressing the spike protein of SARS-CoV-2, 172- and 12.9-fold lower than that of the monomeric and dimeric aptamer-based NLAAs, respectively. Upon testing with 60 clinical saliva samples, the trimeric aptamer-based NLAA achieved a specificity of 100% and a sensitivity of 86.7%. The same nanomaterials were also examined for the ability to block viral entry to host cells. The trimeric aptamer-conjugated nanocubes exhibited a superior neutralizing ability, with an IC<sub>50</sub> value of 6.4 pM, 2.7-fold and 10.1-fold lower than that of the dimeric and monomeric aptamer nanocubes. Moreover, the trimeric aptamer-conjugated nanocubes exhibited excellent biostability and biocompatibility. Overall, our study provides a framework for combating future viral pandemics through the development of a paired biosensor and neutralizing agent made of the same aptamer-modified nanomaterial that recognizes an important viral surface protein like the spike protein of SARS-CoV-2.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 2","pages":"Article 100125"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143705857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced multienzyme-like and antibacterial activity by copper atomically dispersed into molybdenum disulfide for accelerated wound healing 铜原子分散到二硫化钼中加速伤口愈合，增强了多酶样和抗菌活性

Advanced Sensor and Energy Materials Pub Date : 2025-06-01 Epub Date: 2025-03-08 DOI: 10.1016/j.asems.2025.100148

Jiahao Shen , Junli Liu , Yunxiao Yi , Chenhui He , Hengyu Liu , Linrong Shi , Jin Liu , Pingen Shi , Hui Liu , Xuanmeng He , Yi Feng , Xingjian Song , Shaowei Chen

{"title":"Enhanced multienzyme-like and antibacterial activity by copper atomically dispersed into molybdenum disulfide for accelerated wound healing","authors":"Jiahao Shen , Junli Liu , Yunxiao Yi , Chenhui He , Hengyu Liu , Linrong Shi , Jin Liu , Pingen Shi , Hui Liu , Xuanmeng He , Yi Feng , Xingjian Song , Shaowei Chen","doi":"10.1016/j.asems.2025.100148","DOIUrl":"10.1016/j.asems.2025.100148","url":null,"abstract":"<div><div>Bacterial and viral infections have been a global challenge, exacerbated by rampant antibiotic overuse. It is thus of fundamental and technological significance to develop effective antibacterial agents. Herein, copper is atomically dispersed into a MoS<sub>2</sub> matrix via the chelation of ammonium tetrathiomolybdate [(NH<sub>4</sub>)<sub>2</sub>MoS<sub>4</sub>]. Meticulous control of the copper content enables uniform atomic dispersion and optimizes active site accessibility, both critical factors for a range of catalytic activities that mimic native enzymes like peroxidase, superoxide dismutase and glutathione oxidase. Among the series, the Cu/MoS<sub>2</sub>-3 sample, with a Cu:Mo molar ratio of ca. 0.3, exhibits the best activity, with a maximum rate of 14.3 × 10<sup>−18</sup> M s<sup>–</sup><sup>1</sup> in the peroxidase-like reaction with H<sub>2</sub>O<sub>2</sub> and rate constant of 2.56 × 10<sup>−3</sup> s<sup>−1</sup> that are at least one order of magnitude greater than those of MoS<sub>2</sub>. These unique properties endow the resultant Cu/MoS<sub>2</sub> composites with a remarkable antimicrobial activity. Experimentally, with the addition of 1 mM H<sub>2</sub>O<sub>2</sub>, 99% of Gram-positive <em>Staphylococcus aureus</em> and Gram-negative <em>Escherichia coli</em> can be eliminated within 10 min by Cu/MoS<sub>2</sub> (50 μg/mL). Such a peroxidase-like activity of Cu/MoS<sub>2</sub> can facilitate wound healing and inflammation reduction in a <em>Staphylococcus aureus</em> infected wound model. Results from this study highlight the unique significance of atomic dispersion in the structural engineering of high-performance bactericidal agents for biomedical applications.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 2","pages":"Article 100148"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143792342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to “Needle−tip effect promoted flexible electrochemical sensor for detecting chloride ions in food by in−situ deposited silver dendrimers” [Adv Sensor Energy Mater 3 (2024) 100100] “针尖效应促进的柔性电化学传感器用于原位沉积银树突物检测食品中的氯离子”的勘误表[Adv传感器能量物质3 (2024)100100]

Advanced Sensor and Energy Materials Pub Date : 2025-06-01 Epub Date: 2025-03-10 DOI: 10.1016/j.asems.2024.100130

Huang Dai , Huilin Hu , Zhiyong Gong , Jing Shu , Jiahua Wang , Xiaodan Liu , Fuwei Pi , Qiao Wang , Shuo Duan , Yingli Wang

引用次数: 0

Utilizing framework nucleic acids for integrated nano-micro interface system in circulating tumor cells (CTCs) detection, cultivation, and single-cell analysis 利用框架核酸集成纳米微界面系统对循环肿瘤细胞（CTCs）进行检测、培养和单细胞分析

Advanced Sensor and Energy Materials Pub Date : 2025-06-01 Epub Date: 2024-12-10 DOI: 10.1016/j.asems.2024.100131

Qian Chen , Jie Su , Xiaojun Bian, Hongmin Zhang, Shiqi Yang, Juan Yan

{"title":"Utilizing framework nucleic acids for integrated nano-micro interface system in circulating tumor cells (CTCs) detection, cultivation, and single-cell analysis","authors":"Qian Chen , Jie Su , Xiaojun Bian, Hongmin Zhang, Shiqi Yang, Juan Yan","doi":"10.1016/j.asems.2024.100131","DOIUrl":"10.1016/j.asems.2024.100131","url":null,"abstract":"<div><div>The detection and cultivation of circulating tumor cells (CTCs) play a crucial role in monitoring tumor recurrence, metastasis, early disease diagnosis, and assessing the effectiveness of drug treatments. This study specifically focused on investigating human breast cancer cells MCF-7 by utilizing framework nucleic acids (FNAs) as bio-probe scaffold in conjunction with fishbone structures and three-dimensional (3D) microcavity structures within microchannels. These components collectively formed an integrated nano-micro interface system designed for a comprehensive examination of CTC detection and cell culture. The study involved the assessment and comparison of rigid 3D FNAs with distinct side lengths of 7, 13, and 26 bases. This approach not only allowed for precise regulation of the DNA biosensor interface through the manipulation of probe spacing, facilitating optimal probe-cell interactions within the microfluidic channel. Consequently, this approach significantly enhances capture efficiency and lowers the CTC detection limit to 5 cells/mL. Moreover, this research successfully observed cell proliferation and individual cell biological behavior within the 3D microcavity structure. The findings indicated that the overall cell population's proliferation was like that in static culture conditions. Although the proliferation cycle of individual cells was notably extended, cell mobility within the microcavity demonstrated their robust biological activity. These significant outcomes not only offer a practical approach for early tumor detection but also provide a valuable pathway for comprehending mechanisms of tumor development and advancement and guiding personalized treatment strategies effectively.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 2","pages":"Article 100131"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143600910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial: DNA and inorganic nanomaterials for sensors and energy 社论：用于传感器和能源的 DNA 和无机纳米材料

Advanced Sensor and Energy Materials Pub Date : 2025-06-01 Epub Date: 2025-02-25 DOI: 10.1016/j.asems.2025.100138

Lihua Wang

引用次数: 0

Simple surface modification of poly(methyl methacrylate) microfluidic microplates for enhanced ultrasensitive multiplexed detection of infectious diseases 聚甲基丙烯酸甲酯微流控微孔板的简单表面修饰，增强了传染病的超灵敏多路检测

Advanced Sensor and Energy Materials Pub Date : 2025-06-01 Epub Date: 2025-02-28 DOI: 10.1016/j.asems.2025.100142

Sharma T. Sanjay , Sapna Kannan , XiuJun Li

{"title":"Simple surface modification of poly(methyl methacrylate) microfluidic microplates for enhanced ultrasensitive multiplexed detection of infectious diseases","authors":"Sharma T. Sanjay , Sapna Kannan , XiuJun Li","doi":"10.1016/j.asems.2025.100142","DOIUrl":"10.1016/j.asems.2025.100142","url":null,"abstract":"<div><div>Novel strategies for the simultaneous and portable detection of multiple analytes are highly favorable for clinical diagnosis and healthcare. Conventional colorimetric enzyme-linked immunosorbent assay (ELISA) is a widely used laboratory technique for medical diagnostics, quality control, and research applications. However, nonspecific absorption of proteins may lead to a reduction of functional sites, resulting in high background and low sensitivity in ELISA. Herein, we report a simple method of functionalization of poly(methyl methacrylate) (PMMA) with polylysine to be used as the microfluidic microplate substrate for enhanced ELISA, enabling rapid, ultrasensitive, and multiplexed detection of infectious diseases. FTIR and fluorescence microscopy characterization confirmed high amine densities on polylysine-modified PMMA surface, resulting in high detection sensitivity of the colorimetric ELISA on the PMMA microdevice. The ultrasensitive polylysine-modified microplate can immobilize protein within 20 min and results of the assay can be viewed by the naked eye or scanned through a simple desktop scanner for quantitative analysis within 90 min. A sandwich-type immunoassay for the rapid and sensitive detection of immunoglobulin G (IgG), hepatitis B surface antigen (HBsAg), and hepatitis B core antigen (HBcAg) was demonstrated as a proof-of-concept for multiplexed detection. The limits of detection (LOD) of 200.0 pg/mL for IgG, 180.0 pg/mL for HBsAg, and 300.0 pg/mL for HBcAg were achieved, without any specialized equipment like a microplate reader. The surface-modified microchip exhibited about 10-fold higher sensitivity than traditional microplates. This surface-modified microplate has tremendous potential as a point-of-care multiplexed testing platform for many applications ranging from clinical diagnosis to environmental monitoring, particularly in resource-limited settings.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 2","pages":"Article 100142"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143847360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0