Advanced Sensor and Energy Materials最新文献

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Boronic acid-modified cellulose nanocrystal-cored poly(propylene imine) dendrimers as biocompatible glucose-responsive nanocarriers for intelligent insulin delivery and sensing 硼酸修饰纤维素纳米晶核聚丙烯亚胺树状大分子作为智能胰岛素递送和传感的生物相容性葡萄糖反应纳米载体
Advanced Sensor and Energy Materials Pub Date : 2026-03-01 Epub Date: 2026-01-04 DOI: 10.1016/j.asems.2026.100179
Amin Hosseini Sharifabad , Tayebeh Behzad , Mehdi Salami-Kalajahi
{"title":"Boronic acid-modified cellulose nanocrystal-cored poly(propylene imine) dendrimers as biocompatible glucose-responsive nanocarriers for intelligent insulin delivery and sensing","authors":"Amin Hosseini Sharifabad ,&nbsp;Tayebeh Behzad ,&nbsp;Mehdi Salami-Kalajahi","doi":"10.1016/j.asems.2026.100179","DOIUrl":"10.1016/j.asems.2026.100179","url":null,"abstract":"<div><div>Precise regulation of blood glucose level is essential for the long-term and effective management of diabetes. In this context, glucose-responsive insulin delivery systems have emerged as an innovative strategy for smart and self-regulated insulin release. This study develops a nanocarrier based on nanocrystalline cellulose (CNC)-cored poly(propylene imine) (PPI) dendrimers (CPG) functionalized with 4-carboxyphenylboronic acid (CPB), denoted as CPG<sub>x</sub>-CPB. Titration approach showed that dendrimer amine groups lowered the p<em>K</em><sub>a</sub> of CPB, improving its responsiveness at physiological pH. Insulin-loaded CPG<sub>3</sub>-CPB and CPG<sub>4</sub>-CPB systems achieved encapsulation efficiencies of 73.6% and 85.8%, and loading capacities of 17.8% and 21.7%, respectively. While the third-generation dendrimer provided greater internal space, the fourth generation offered more binding sites for insulin. Insulin release remained low (∼10%) under acidic conditions (simulated gastric fluid (SGF), pH = 1.2), but significantly increased under neutral conditions (simulated intestinal fluid (SIF), pH = 6.8) and elevated glucose levels, reaching up to 65% due to boronate-glucose complex formation. MTT assay showed ∼100% cell viability up to 200 μg/mL. Kinetic modeling showed that the Higuchi and Korsmeyer-Peppas models best fit the release profile. Furthermore, the system exhibited reversible glucose-responsive behavior, acting as a smart sensor through observable fluorescence and colorimetric changes.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"5 1","pages":"Article 100179"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147398484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bionic radical-polymerization tailored nanofilm sensor for long-term in vivo monitoring ionic dynamics in cerebrospinal fluid 仿生自由基聚合定制纳米膜传感器长期在体内监测脑脊液中的离子动力学
Advanced Sensor and Energy Materials Pub Date : 2026-03-01 Epub Date: 2026-01-22 DOI: 10.1016/j.asems.2026.100181
Chen Liu , Yongqi Cheng , Zhijie Wang , Lehui Lu
{"title":"Bionic radical-polymerization tailored nanofilm sensor for long-term in vivo monitoring ionic dynamics in cerebrospinal fluid","authors":"Chen Liu ,&nbsp;Yongqi Cheng ,&nbsp;Zhijie Wang ,&nbsp;Lehui Lu","doi":"10.1016/j.asems.2026.100181","DOIUrl":"10.1016/j.asems.2026.100181","url":null,"abstract":"<div><div>Cerebrospinal fluid (CSF) plays a crucial role in maintaining central nervous system (CNS) function by regulating ionic homeostasis. Disruptions in CSF ionic strength are closely linked to the progression of neurological disorders such as Parkinson's disease (PD) and glioma. However, continuous <em>in vivo</em> monitoring of these ionic dynamics remains a major challenge due to limitations in existing sensing technologies. Inspired by the formation of neuromelanin, we present a flexible electrochemical sensor engineered via a one-step, mild co-polymerization with no residual organic solvents strategy that leverages dopamine-derived radicals to initiate the electrochemical polymerization of pyrrole. This process yields a conductive, hydrophilic, and biocompatible polydopamine-pyrrole composite layer optimized for stable interfacing with neural tissue. When applied in murine models of PD and glioma, the nanosensor enables long-term, real-time monitoring of CSF ionic fluctuations throughout disease progression. These results offer new insights into the pathophysiological roles of ionic imbalance and establish a robust platform for neurochemical monitoring with potential applications in early diagnosis and therapeutic development.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"5 1","pages":"Article 100181"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147398479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-cost optical multi-wavelength sensor for accurate real-time state-of-charge monitoring in vanadium flow batteries 用于钒液流电池精确实时监测的低成本光学多波长传感器
Advanced Sensor and Energy Materials Pub Date : 2026-03-01 Epub Date: 2026-02-05 DOI: 10.1016/j.asems.2026.100183
Ange A. Maurice, Pablo A. Prieto-Díaz, Marcos Vera
{"title":"Low-cost optical multi-wavelength sensor for accurate real-time state-of-charge monitoring in vanadium flow batteries","authors":"Ange A. Maurice,&nbsp;Pablo A. Prieto-Díaz,&nbsp;Marcos Vera","doi":"10.1016/j.asems.2026.100183","DOIUrl":"10.1016/j.asems.2026.100183","url":null,"abstract":"<div><div>We present a novel, low-cost optical sensor for accurate real-time monitoring of the state of charge (SoC) and total vanadium concentration in vanadium flow batteries. Using only six discrete wavelengths, the sensor achieves precision comparable to full-spectrum methods while significantly reducing equipment costs and complexity. A general deconvolution method is used to measure the SoC and the total vanadium concentration in both the negolyte and posolyte, with calibration covering concentrations from 1.21 to 1.82 mol/L. We achieve root mean square error (RMSE) values of 1.2% and 3.2% for the SoC, and 54 mmol/L and 97 mmol/L for the total vanadium concentration in the negolyte and posolyte, respectively, demonstrating excellent agreement with reference ultraviolet visible (UV-vis) data. In addition, a wavelength optimization study is proposed to determine the optimal number and placement of spectral channels, providing a basis for the design of tailored optical sensors for vanadium electrolytes.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"5 1","pages":"Article 100183"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147398482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Battery-less implantable sensor for real-time intrasac pressure monitoring in EVAR-treated AAAs 无电池植入式传感器用于evar处理的AAAs的实时腔内压力监测
Advanced Sensor and Energy Materials Pub Date : 2026-03-01 Epub Date: 2025-11-07 DOI: 10.1016/j.asems.2025.100170
Giulio Saroglia , Salvatore Diana , Stefano Marocco , Matteo Metaldi , Shasa Nicoloso , Matteo Tozzi , Igor Stefanini
{"title":"Battery-less implantable sensor for real-time intrasac pressure monitoring in EVAR-treated AAAs","authors":"Giulio Saroglia ,&nbsp;Salvatore Diana ,&nbsp;Stefano Marocco ,&nbsp;Matteo Metaldi ,&nbsp;Shasa Nicoloso ,&nbsp;Matteo Tozzi ,&nbsp;Igor Stefanini","doi":"10.1016/j.asems.2025.100170","DOIUrl":"10.1016/j.asems.2025.100170","url":null,"abstract":"<div><h3>Objective</h3><div>To develop and bench-validate a fully passive, wireless implantable pressure monitoring system (WIPS) for on-demand assessment of intra-sac pressure in patients with endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms.</div></div><div><h3>Methods</h3><div>WIPS includes a flexible 15 mm × 145 mm implant integrating four pressure sensors (MS5839), an RFID tag (ST25DV04KC), and an ultra-low-power microcontroller (STM32L011). The device is powered wirelessly via 13.56 MHz RFID, enabling pressure measurements at configurable resolutions without need for batteries. Data is stored locally and retrieved via an external Reader (RD520). Benchtop tests evaluated power consumption, telemetry range, and sensor linearity in air, heated saline, and a biologically representative meat model. Uniform 1 μm and 2 μm Parylene C coatings were applied intentionally, as two predefined thickness conditions, to evaluate biocompatibility without compromising sensor performance.</div></div><div><h3>Results</h3><div>Total power consumption remained below 4 mW across all oversampling ratios (OSRs). In free air, reliable telemetry was achieved up to 24 cm at 6 W Reader output. Heated mineral water reduced the optimal distance to 16 cm, and physiological saline limited it to 4 cm. In the Meat Model, a fixed 18 cm tissue path yielded 100% link reliability for OSR ≤ 1024 at 5 W. Parylene C coatings did not alter pressure linearity or hysteresis. The strip is compatible with a 20 F delivery sheath, suggesting compatibility with standard EVAR catheters.</div></div><div><h3>Conclusions</h3><div>WIPS combines low power consumption, deep-tissue wireless telemetry, and catheter-based deliverability, addressing longstanding limitations in implantable EVAR surveillance tools. These benchtop findings support feasibility for future <em>in vivo</em> testing in large animal models to validate long-term safety and clinical integration.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"5 1","pages":"Article 100170"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145963176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tetrahedral DNA-Linker stable Europium nanoparticles for ultrasensible time-resolved fluorescence lateral flow immunoassay 用于超灵敏时间分辨荧光侧流免疫分析的四面体dna -连接剂稳定的铕纳米颗粒
Advanced Sensor and Energy Materials Pub Date : 2026-03-01 Epub Date: 2025-12-03 DOI: 10.1016/j.asems.2025.100176
Fei Wang , Yefei Duan , Haiou Yang , Xiaoguo Liu , Ming Xu , Jielin Sun , Shihua Luo , Fuyou Li
{"title":"Tetrahedral DNA-Linker stable Europium nanoparticles for ultrasensible time-resolved fluorescence lateral flow immunoassay","authors":"Fei Wang ,&nbsp;Yefei Duan ,&nbsp;Haiou Yang ,&nbsp;Xiaoguo Liu ,&nbsp;Ming Xu ,&nbsp;Jielin Sun ,&nbsp;Shihua Luo ,&nbsp;Fuyou Li","doi":"10.1016/j.asems.2025.100176","DOIUrl":"10.1016/j.asems.2025.100176","url":null,"abstract":"<div><div>Accurate quantification of interleukin-6 (IL6), a biomarker central to sepsis and cytokine release syndrome, is essential for assessing disease severity. Here, we present a high-performance lateral flow assay (LFA) that leverages a novel conjugate: europium nanoparticles (EuNPs) labels linked via tetrahedral DNA frameworks (TDFs). The TDF precisely controls antibody orientation, minimizes nonspecific binding, and improves conjugate stability. Combined with the strong, time-resolved fluorescence of EuNPs, this design achieves a broad dynamic range and preserves linearity at high analyte concentrations. The platform quantitatively detects IL6 from 0 to 5000 pg/mL within 10 min, showing excellent agreement with reference methods. This DNA-nanostructure-enhanced approach provides a robust and portable point-of-care testing strategy for critical clinical decision-making.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"5 1","pages":"Article 100176"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145963175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydrothermal synthesis parameter engineering and mass loading of polyaniline electrodes for high-performance supercapacitors 高性能超级电容器用聚苯胺电极的水热合成、参数工程及质量加载
Advanced Sensor and Energy Materials Pub Date : 2026-03-01 Epub Date: 2025-12-22 DOI: 10.1016/j.asems.2025.100177
Mamta Bulla , Vinay Kumar , Annu Sheokand , Sarita Sindhu , Raman Devi , Sunil Kumar , Ajay Kumar Mishra
{"title":"Hydrothermal synthesis parameter engineering and mass loading of polyaniline electrodes for high-performance supercapacitors","authors":"Mamta Bulla ,&nbsp;Vinay Kumar ,&nbsp;Annu Sheokand ,&nbsp;Sarita Sindhu ,&nbsp;Raman Devi ,&nbsp;Sunil Kumar ,&nbsp;Ajay Kumar Mishra","doi":"10.1016/j.asems.2025.100177","DOIUrl":"10.1016/j.asems.2025.100177","url":null,"abstract":"<div><div>The increasing demand for compact, portable, and cost-effective energy storage fuels advancements in supercapacitors, where achieving high capacitance at elevated mass loadings and excellent rate capability with materials like polyaniline (PANI) is key to enhancing energy density without compromising high power density. This study investigates the effect of synthesis temperature of PANI over a range of 60 °C–140 °C and reaction time (3, 5 and 7 h), to enhance its electrochemical performance. Among the various conditions tested, PANI synthesized at 80 °C for 5 h (P-80 °C (5 h)) demonstrated optimal performance. The optimized sample was further evaluated at high mass loadings ranging from 1 to 10 mg cm<sup>−2</sup>, exhibiting a specific capacitance of 356 F g<sup>−1</sup> at 1 mV s<sup>−1</sup> for a 1 mg cm<sup>−2</sup> mass. Notably, at 7 mg cm<sup>−2</sup>, the electrode achieved an impressive areal capacitance of 1172 mF cm<sup>−2</sup> and a specific capacitance of 167.4 F g<sup>−1</sup>. A symmetric supercapacitor device configured as PANI//PANI, with a total active mass of 7 mg, employing a hydrogel electrolyte (H<sub>2</sub>SO<sub>4</sub>), delivered an areal capacitance of 812 mF cm<sup>−2</sup> and a specific capacitance of 117 F g<sup>−1</sup> at a scan rate of 1 mV s<sup>−1</sup>. Furthermore, the device retained 76.2% of its initial capacitance after 5000 charge-discharge cycles at a current density of 10 mA cm<sup>−2</sup>. These findings highlight the promise of hydrothermally synthesized PANI and hydrogel electrolytes for advancing high-performance supercapacitors.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"5 1","pages":"Article 100177"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147398483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DNA-origami-engineered NAC-linkers enable the construction of humanized liver organoids for modeling ischemia-reperfusion injury dna折纸工程nac连接物能够构建人源化肝类器官,用于模拟缺血再灌注损伤
Advanced Sensor and Energy Materials Pub Date : 2026-03-01 Epub Date: 2026-01-23 DOI: 10.1016/j.asems.2026.100180
Tianfei Lu , Hao Ji , Qing Li , Jiang Zhang , Guangqi Song , Heming Wang , Changfeng Zhu , Chong Dong , Yanjun Shi
{"title":"DNA-origami-engineered NAC-linkers enable the construction of humanized liver organoids for modeling ischemia-reperfusion injury","authors":"Tianfei Lu ,&nbsp;Hao Ji ,&nbsp;Qing Li ,&nbsp;Jiang Zhang ,&nbsp;Guangqi Song ,&nbsp;Heming Wang ,&nbsp;Changfeng Zhu ,&nbsp;Chong Dong ,&nbsp;Yanjun Shi","doi":"10.1016/j.asems.2026.100180","DOIUrl":"10.1016/j.asems.2026.100180","url":null,"abstract":"<div><div>Hepatic ischemia-reperfusion injury (IRI) is a major cause of liver dysfunction and failure following surgical procedures such as liver resection and transplantation. Although numerous studies have reported various underlying mechanisms involving both parenchymal and nonparenchymal cells, there is an urgent need to develop human-relevant models that faithfully recapitulate clinical IRI. To address this, we established a novel three-dimensional liver organoid model using NAC linker technology to simulate hepatic IRI in both murine and human contexts. By coculturing primary hepatocytes with nonparenchymal cells (NPCs) and immune components such as peripheral blood mononuclear cells (PBMCs) or THP-1 monocytes, we developed multicellular organoids that recapitulate key structural and functional features of the liver. We demonstrated that oxidative stress induced by H<sub>2</sub>O<sub>2</sub> triggers inflammatory and apoptotic responses consistent with IRI, which are exacerbated by immune cell involvement. Furthermore, we identified the YAP signaling pathway as a critical protective mechanism: its activation attenuated cellular damage and inflammation, whereas its inhibition worsened injury. These findings highlight the utility of NAC-liver organoids as a robust platform for studying IRI mechanisms and screening therapeutic agents, with YAP agonists emerging as promising candidates for mitigating IRI-related damage.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"5 1","pages":"Article 100180"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147398480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid 3D printing of PEDOT:PSS-based flexible bio-electrodes 快速3D打印PEDOT:基于pss的柔性生物电极
Advanced Sensor and Energy Materials Pub Date : 2026-03-01 Epub Date: 2026-01-08 DOI: 10.1016/j.asems.2026.100178
Haofan Liu , Yiting Huang , Jianxin Shi , Ya Ren , Xia Luo , Mariya Edeleva , Tong Qi , Liming He , Li Zhang , Yinchu Dong , Xide Dai , Ludwig Cardon , Xiaohong Li , Maling Gou
{"title":"Rapid 3D printing of PEDOT:PSS-based flexible bio-electrodes","authors":"Haofan Liu ,&nbsp;Yiting Huang ,&nbsp;Jianxin Shi ,&nbsp;Ya Ren ,&nbsp;Xia Luo ,&nbsp;Mariya Edeleva ,&nbsp;Tong Qi ,&nbsp;Liming He ,&nbsp;Li Zhang ,&nbsp;Yinchu Dong ,&nbsp;Xide Dai ,&nbsp;Ludwig Cardon ,&nbsp;Xiaohong Li ,&nbsp;Maling Gou","doi":"10.1016/j.asems.2026.100178","DOIUrl":"10.1016/j.asems.2026.100178","url":null,"abstract":"<div><div>The integration of biotechnology and information technology has created a growing demand for high-performance flexible bio-electrodes. However, existing conductive polymer systems often struggle to simultaneously achieve high electrical conductivity, excellent stretchability, and high-resolution circuitry that are essential for soft bioelectronics. To address these challenges, we developed a light-curable, elastomeric bio-electrode consisting of a dual-network conductive hydrogel system combining poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS) with a photo-crosslinkable Pluronic hydrogel. Utilizing digital light processing (DLP)-based three-dimensional (3D) printing technology, this bio-electrode can be rapidly prototyped with customized, high-resolution electrode structures and tailored packaging. Subsequent acid treatment induces molecular chain rearrangement within the electrode, resulting in a denser network topology and significantly enhanced electrical conductivity. Consequently, these flexible electrodes exhibit excellent electrical performance exceeding 300 S/m, while maintaining remarkable flexibility and stretchability. The fabricated electrodes demonstrate good biocompatibility and are capable of delivering electrical stimulation to biological tissues or recording cortical neural signals. This approach provides an efficient strategy for customizing high-performance flexible bio-electrodes, holding significant promise for future medical applications.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"5 1","pages":"Article 100178"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147398481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Target triggered G4 catalytic network via HCR-mediated hydrogel assembly for multi-model analysis of microRNA efficiently 目标通过hcr介导的水凝胶组装触发G4催化网络,高效地进行microRNA的多模型分析
Advanced Sensor and Energy Materials Pub Date : 2025-12-01 Epub Date: 2025-07-02 DOI: 10.1016/j.asems.2025.100158
Mingli Su , Jun Yang , Ruiwen Wang , Jiabao Yang , Fahui Wang , Jiamin Qin , Weiguo Yang , Qing-Chun Deng , Chengyi Xiong , Wen-Bin Liang
{"title":"Target triggered G4 catalytic network via HCR-mediated hydrogel assembly for multi-model analysis of microRNA efficiently","authors":"Mingli Su ,&nbsp;Jun Yang ,&nbsp;Ruiwen Wang ,&nbsp;Jiabao Yang ,&nbsp;Fahui Wang ,&nbsp;Jiamin Qin ,&nbsp;Weiguo Yang ,&nbsp;Qing-Chun Deng ,&nbsp;Chengyi Xiong ,&nbsp;Wen-Bin Liang","doi":"10.1016/j.asems.2025.100158","DOIUrl":"10.1016/j.asems.2025.100158","url":null,"abstract":"<div><div>With the advancement of hierarchical diagnosis and treatment systems, there is an increasing demand for rapid, user-friendly, and cost-effective approaches for disease analysis and prognosis monitoring. MicroRNAs (miRNAs), as vital biomarkers for early-stage disease diagnosis, pose substantial analytical challenges due to their small molecular size, low endogenous abundance, and high sequence homology among different species. Traditional methods such as Northern blotting and real-time ​polymerase chain reaction (RT-PCR) are limited by their complexity, lengthy procedures, and reliance on specialized instruments, making them less suitable for point-of-care (POC) applications. To address these challenges, we propose a portable and efficient POC analytical platform by utilizing a G4 catalytic network triggered by miRNA-155 through hybridization chain reaction (HCR)-mediated hydrogel assembly. A highly sensitive analysis was achieved for concentrations of 500 pM and 100 ​nM, with a limit of detection (LOD) of 138 pM, which demonstrated the method's capability for precise detection at low concentrations. Additionally, based on the color development reaction, its image information <em>via</em> RGB analysis could be used to achieve ternary precise quantitative analysis, thereby improving the analysis sensitivity and portability. This innovative platform provides a simple, cost-effective, and customizable solution for miRNA detection, opening new avenues for home-based bioanalysis and early disease diagnosis in resource-limited or remote settings.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 4","pages":"Article 100158"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synergistic effect of MWCNT enriched MgWO4 hybrid electrode for practical device assisted pouch type asymmetric supercapacitor devices MWCNT富集MgWO4杂化电极在实用器件辅助袋型非对称超级电容器器件中的协同效应
Advanced Sensor and Energy Materials Pub Date : 2025-12-01 Epub Date: 2025-10-13 DOI: 10.1016/j.asems.2025.100169
Uma Shankar Veerasamy , Anandh Jesuraj S , Suganya Palani , Yuto Fujita , Yasuharu Matsunaga , Toshihiro Kuzuya , Chihiro Sekine , Yuttana Mona
{"title":"Synergistic effect of MWCNT enriched MgWO4 hybrid electrode for practical device assisted pouch type asymmetric supercapacitor devices","authors":"Uma Shankar Veerasamy ,&nbsp;Anandh Jesuraj S ,&nbsp;Suganya Palani ,&nbsp;Yuto Fujita ,&nbsp;Yasuharu Matsunaga ,&nbsp;Toshihiro Kuzuya ,&nbsp;Chihiro Sekine ,&nbsp;Yuttana Mona","doi":"10.1016/j.asems.2025.100169","DOIUrl":"10.1016/j.asems.2025.100169","url":null,"abstract":"<div><div>We developed the high performance supercapacitor device using of the MgWO<sub>4</sub> electrode by adding multiwall carbon nanotube (MWCNT). Here, the MWCNT-supported MgWO<sub>4</sub> nanocomposite was prepared through the simple hydrothermal method. The varying percentages of MWCNT addition have enhanced the electrochemical performance of MgWO<sub>4</sub>. The prepared MgWO<sub>4</sub>@M-5 (736 ​F/g) electrode exhibited an excellent specific capacitance value compared to other electrodes, including MgWO<sub>4</sub> (236 ​F/g), MgWO<sub>4</sub>@M-0.5 (316 ​F/g), MgWO<sub>4</sub>@M ​− ​1 (522 ​F/g), MgWO<sub>4</sub>@M-3 (641 ​F/g) and MgWO<sub>4</sub>@M-7 (561 ​F/g). Moreover, the MgWO<sub>4</sub>@M-5 electrode is utilized as the positive electrode and the activated carbon (AC) is used as the negative electrode for the construction of a pouch-type asymmetric supercapacitor device (ASC). The MgWO<sub>4</sub>@M-5//AC ASC device shows the maximum specific capacity of 166 mAh/g. In addition, the MgWO<sub>4</sub>@M-5//AC ASC device delivered a higher energy density of 31.12 ​Wh/kg with the corresponding power density of 800 ​W/kg. The MgWO<sub>4</sub>@M-5//AC ASC device exhibits a capacity retention of 86.23% over 10,000 cycles. In addition, serially connecting two devices has effectively rotated the electric motor fan, and glowing the LED light is the proof of the concept of the fabricated device.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 4","pages":"Article 100169"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145466390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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