Advanced Sensor and Energy Materials最新文献

{"title":"Progress in ion detection and clinical diagnosis based on G-quadruplex combined with fluorescence properties","authors":"Ping Lu,&nbsp;Gerile Aodeng,&nbsp;Jun Ai","doi":"10.1016/j.asems.2024.100112","DOIUrl":"10.1016/j.asems.2024.100112","url":null,"abstract":"<div><p>G-quadruplex is a high-level structure composed of folded DNA or RNA rich in tandem repeats of guanine (G). In recent years, G-quadruplex is widely used in various fields due to its unique structural properties. This article briefly introduces the structural properties of G-quadruplex, and provides a brief introduction to the research on DNA and RNA G-quadruplex in various detection and medical fields. It is hoped that this can provide some help to readers who want to understand G-quadruplex.</p></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"3 3","pages":"Article 100112"},"PeriodicalIF":0.0,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773045X24000232/pdfft?md5=db550d692d7790638c0821d05b2d7164&pid=1-s2.0-S2773045X24000232-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141623710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of ratiometric DNA biosensors with improved accuracy, precision, and signal-to-noise ratio","authors":"Qing Tao ,&nbsp;Yanli Wen ,&nbsp;Wen Liang ,&nbsp;Lele Wang ,&nbsp;Ruiyan Guo ,&nbsp;Min Ding ,&nbsp;Ming Luo ,&nbsp;Juan Yan ,&nbsp;Feiyan Gong ,&nbsp;Chengming Cao ,&nbsp;Lanying Li ,&nbsp;Gang Liu","doi":"10.1016/j.asems.2024.100106","DOIUrl":"10.1016/j.asems.2024.100106","url":null,"abstract":"<div><p>Ratiometric DNA biosensors, which utilize DNA as the recognition element and integrate dual signals from diverse sensing platforms including fluorescence, electrochemistry, and surface-enhanced Raman scattering (SERS), have demonstrated remarkable proficiency in detecting a wide range of targets. In this review, we showcase the significant progress achieved by ratiometric biosensors. Firstly, ratiometric biosensors have made notable advancements in analyzing real samples. These include the analysis of pH values near cancer cells, quantification of miRNA in human cell lysates, detection of human telomerase RNA in cell extracts, and performing DNA logic-gated in situ bioimaging on cell membranes. Secondly, excellent sensitivity has been attained through the utilization of effective amplification methods such as RCA, HCR, and CHA, among others. Thirdly, the construction of stable reference signals has resulted in significantly improved precision for ratiometric biosensors. This breakthrough has overcome matrix effects, enabling reliable detection in real samples with high selectivity. This review provides a comprehensive overview of recent advancements in strategies employed by ratiometric DNA biosensors. We present three types of biosensors based on distinct sensing platforms: fluorescent, electrochemical, and SERS biosensors. Additionally, we discuss future directions and primary challenges in the development of ratiometric DNA biosensors.</p></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"3 3","pages":"Article 100106"},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773045X24000177/pdfft?md5=5fda3b8ad47d6ebe87ce68c44cf8fd62&pid=1-s2.0-S2773045X24000177-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141033191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the synthesis, characteristics, electrical conductivity, photocatalytic activity, and electrochemical activity of eco-friendly zinc oxide nanoparticles","authors":"Redwanul Islam ,&nbsp;Suprio Shantanu Saha ,&nbsp;Reana Raen ,&nbsp;Nayeemul Islam ,&nbsp;Torikul Islam","doi":"10.1016/j.asems.2024.100105","DOIUrl":"10.1016/j.asems.2024.100105","url":null,"abstract":"<div><p>The <em>Nigella Sativa</em> seeds were utilized for the environment-friendly zinc oxide nanoparticles (ZnO NPs), as evident by the observation of a white precipitate. Numerous analytical techniques, such as XRD, FTIR, UV–vis, SEM, and EDX, were utilized to describe the specimen's structural, optical, and electrical properties. XRD analysis was used to confirm that the ZnO NPs were crystalline. An absorbance peak at 401 nm was observed in the UV–vis, indicating that the ZnO NPs have a 2.91 eV bandgap. Functional groups are present in ZnO NPs, as seen by the FTIR graph. The nanoparticles' spherical form and average size of 37.9 nm were confirmed by the SEM image. EDX analysis confirmed the composition of the nanoparticles, with zinc accounting for 73.17% and oxygen for 26.83%. ZnO NPs demonstrated excellent electrical conductivity because of their higher surface-to-volume ratio. Additionally, the synthesis of ZnO NPs exhibited effective degradation of methylene blue dye. These results point to potential applications in several domains, including electronics, biomedical devices, industry, and agriculture, and they call for immediate follow-up research.</p></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"3 3","pages":"Article 100105"},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773045X24000165/pdfft?md5=694b8a30b8b6232e98fb18669ace6289&pid=1-s2.0-S2773045X24000165-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141052514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-in-one DNA nanowheels for simultaneous tumor regression and drug resistance prevention in breast cancer model","authors":"Ping Li ,&nbsp;Chun-Feng Feng ,&nbsp;Peng-Fei Lyu ,&nbsp;Fei Liu ,&nbsp;Hui-Sheng Li ,&nbsp;Li-Qun Zhang","doi":"10.1016/j.asems.2024.100104","DOIUrl":"10.1016/j.asems.2024.100104","url":null,"abstract":"<div><p>Herein, we proposed novel three-in-one DNA nanowheels with simultaneous chemo and gene therapy to treat tumor, especially to prevent simultaneous drug resistance, which could be disassembled <em>via</em> a cascaded hybridization reactions triggered by the highly expressed microRNA in cancer cells for smart and efficient cancer therapy. Typically, with breast cancer as a model, microRNA 21 could trigger the self-disassembly of DNA nanowheel 1 <em>via</em> hybridization with a specially designed oligonucleotide (anti-microRNA 21) in DNA nanowheel 1, releasing another special oligonucleotide (Contact sequence) to trigger the self-disassembly of DNA nanowheel 2 with releasing of a special oligonucleotide (anti-Contact sequence) to trigger the self-disassembly of DNA nanowheel 1 cyclically, and thus the cascaded hybridization reactions with three-in-one anti-cancer functions could be generated based on three main therapeutic effects <em>via</em> releasing doxorubicin to inhibit macromolecular biosynthesis, antisense oligonucleotide of microRNA 21 to activate the apoptotic cell pathway and antisense oligonucleotide of MDR1 to prevent the drug resistance respectively. As expected, the proposed method showed improved therapeutic efficacy on the cancer cells with about 80% apoptosis ratio, especially on the drug resistant cancer cells with about 75% apoptosis ratio, compared with that in the conventional anti-cancer systems of about 70% on cancer cells and below 40% on drug resistant cancer cells, respectively. Most importantly, this strategy opened the door for generation of complex functional DNA-based structures for target triggering drugs releasing system combining with chemo- and gene-therapy to generate tumor regression and prevent drug resistance with an optimized therapeutic efficacy, providing a new avenue for efficient cancer treatment, especially drug resistant cancers.</p></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"3 3","pages":"Article 100104"},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773045X24000153/pdfft?md5=ac5e863c59149740a770207108aac21b&pid=1-s2.0-S2773045X24000153-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141045037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pencil drawn interdigitated capacitive sensors on wood substrate","authors":"","doi":"10.1016/j.asems.2024.100103","DOIUrl":"10.1016/j.asems.2024.100103","url":null,"abstract":"<div><p>This research presents the fabrication and characterization of an interdigitated capacitive (IDC) sensor on a wooden substrate using pencil traces. The resistance of the pencil traces decreased from 100 kΩ to 5 kΩ as the pencil grade shifted from HB to 8B. Concurrently, capacitance measurements revealed an increase from approximately 5 pF for a 5-finger IDC made with HB pencil to around 32 pF for an 8B pencil counterpart. Increasing the number of pencil traces from 10 to 50 resulted in a significant decrease in resistance and a proportional increase in capacitance. Application of the IDC sensor demonstrated notable changes in capacitance upon proximity and touch, with a significant decrease upon removal. The interdigitated capacitance sensor exhibits good proximity effects and contact sensitivity in touch, with capacitance increasing exponentially from 0.3 pF (7 cm) to 1.2 pF (direct contact), highlighting its ability to detect objects with high precision. Additionally, environmental factors such as temperature and humidity influence capacitance values. These findings underscore the potential of pencil-drawn IDC sensors for responsive and adaptable applications in various fields.</p></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"3 4","pages":"Article 100103"},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773045X24000141/pdfft?md5=7636fc9618b2d2125a50e0329f4d402b&pid=1-s2.0-S2773045X24000141-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140778500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the impact of delayed centrifugation on protein profiles analyzed by LC/MS in serum and plasma samples","authors":"Jingyi Si ,&nbsp;Yifan Gao ,&nbsp;Binjian Yan ,&nbsp;Xizhong Shen ,&nbsp;Changfeng Zhu ,&nbsp;Qunyan Yao","doi":"10.1016/j.asems.2024.100101","DOIUrl":"https://doi.org/10.1016/j.asems.2024.100101","url":null,"abstract":"<div><p>The pre-analytical steps in blood-based liquid biopsy, involving sample collection techniques and storage conditions, play a critical role in ensuring the integrity and reliability of collected samples. These steps have a directly impact on the accuracy and reliability of test results and are therefore of utmost importance. Mass spectrometry (MS)-based proteomics is an exceptionally powerful tool in the field of liquid biopsy. It enables the comprehensive analysis of the protein content within biological specimens, providing valuable insights into the underlying mechanisms and pathogenesis of diseases. In this study, we aim to explore the variations in the protein landscape between serum and plasma specimens and evaluate the impact of delayed centrifugation on LC/MS-analyzed protein profiles. We seek to provide recommendations on optimal pre-analytical protocols for MS-based proteomics studies. This will enhance the accuracy and reliability of liquid biopsy for precision medicine, ultimately leading to improved patient outcomes.</p></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"3 2","pages":"Article 100101"},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773045X24000128/pdfft?md5=493e773c29b819f9ead66dea824ec007&pid=1-s2.0-S2773045X24000128-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140650503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heteroatom self-doped graphitic carbon materials from Sargassum thunbergii with improved supercapacitance performance","authors":"Hui Xu ,&nbsp;Lina Dong ,&nbsp;Bing Zhang ,&nbsp;Kun Wang ,&nbsp;Jiafeng Meng ,&nbsp;Yanwei Tong ,&nbsp;Hua Wang","doi":"10.1016/j.asems.2024.100102","DOIUrl":"https://doi.org/10.1016/j.asems.2024.100102","url":null,"abstract":"<div><p>It is well-known that high specific surface area and improved pore structure is significantly desired for the application of supercapacitor based on biomass-based activated carbon. Herein, <em>Sargassum thunbergii</em> was selected as carbon precursor. Then, a simple and environmentally friendly method was designed to synthesize heteroatom self-doped porous carbon materials via synchronous activation and graphitization by using K₂FeO₄. Our results demonstrated that activation temperature plays an important role in porous structure, morphology, and degree of graphitization, thus affecting the performance of supercapacitance. <em>Sargassum thunbergii</em>-based graphitized porous carbons STGPC-2 sample (calcination temperature at 700 °C) has a large specific surface area (1641.98 m² g⁻¹), pore volume (0.91 cm³ g⁻¹), high microporosity (<em>V</em>_micro = 0.62 cm³ g⁻¹, more than 68%), and a certain degree of graphitization. In three-electrode system, The STGPC-2 electrode exhibited a high specific capacitance of 325.5 F g⁻¹ at 0.5 A g⁻¹ and displays high rate capability (248 F g⁻¹ at 10 A g⁻¹ in 6 M KOH electrolyte). The symmetric STGPC-2 supercapacitor exhibits energy density as high as 21.3 Wh kg⁻¹ (at a power density of 450 W kg⁻¹) and excellent long-term cycling stability (97% capacitance retention after 3000 cycles) in 1 M Na₂SO₄ electrolyte.</p></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"3 2","pages":"Article 100102"},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773045X2400013X/pdfft?md5=bd62eca1a8a03cd062b2029088d24f3c&pid=1-s2.0-S2773045X2400013X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140893606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Needle−tip effect promoted flexible electrochemical sensor for detecting chloride ions in food by in−situ deposited silver dendrimers","authors":"Huang Dai ,&nbsp;Huilin Hu ,&nbsp;Zhiyong Gong ,&nbsp;Jing Shu ,&nbsp;Jiahua Wang ,&nbsp;Xiaodan Liu ,&nbsp;Fuwei Pi ,&nbsp;Qiao Wang ,&nbsp;Shuo Duan ,&nbsp;Yingli Wang","doi":"10.1016/j.asems.2024.100100","DOIUrl":"10.1016/j.asems.2024.100100","url":null,"abstract":"<div><p>Salt plays a crucial role in food processing and consumption, and the rapid detection of chloride ions in food and feed has great significance for practical applications. In this work, Ag−based nanomaterials were deposited on the surface of a flexible integrated electrochemical sensor for the detection of Cl⁻ in food. In order to enhance the detection performance, a unique needle−tip structure was formed by manipulating the electro−engraving process during the electrodeposition growth. Theoretical calculations and electrochemical investigations have demonstrated that the dendrimer’s rich tip structure significantly enhanced its electrochemical performance. A sensitive and flexible integrated electrochemical sensor was creatively developed for the detection of Cl⁻ using needle−tip effect−promoted Ag micro dendrimers. The sensor achieved quantitative detection of Cl⁻ over a dynamic range of 10.0 μM–100.0 mM, with a low limit of detection of 0.148 μM. The flexible electrochemical sensor proposed in this work exhibited good repeatability, selectivity and recoveries in real food samples.</p></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"3 4","pages":"Article 100100"},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773045X24000116/pdfft?md5=7f1732a8a93054fff68eb3a6c33e9d2c&pid=1-s2.0-S2773045X24000116-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141997598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for special issue: Electrochemical sensing and imaging","authors":"","doi":"10.1016/j.asems.2024.100099","DOIUrl":"10.1016/j.asems.2024.100099","url":null,"abstract":"","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"3 3","pages":"Article 100099"},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773045X24000104/pdfft?md5=6295c498bc908c19532df6942037e748&pid=1-s2.0-S2773045X24000104-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140268220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coating tetrahedral DNA framework with endosomolytic peptides for improved stability and cytosolic delivery","authors":"Jinjun He ,&nbsp;Xiang Ji ,&nbsp;Zihui Xu ,&nbsp;Wei He ,&nbsp;Yan Zhao ,&nbsp;Lele Sun ,&nbsp;Lan Ma","doi":"10.1016/j.asems.2024.100098","DOIUrl":"10.1016/j.asems.2024.100098","url":null,"abstract":"<div><p>DNA nanostructures have emerged as promising carriers for drug delivery. However, challenges such as low stability, poor cellular uptake efficiency, and vulnerability to lysosomal degradation still hinder their therapeutic potential. In this study, we demonstrate the coating of tetrahedral DNA frameworks (TDF) with the endosomolytic peptide L17E through electrostatic interactions to address these issues. Our findings highlight that L17E coating substantially enhances the stability of TDFs and improves their uptake efficiency into RAW264.7 cells through endocytosis and macropinocytosis. Moreover, L17E coating enables efficient endosomal release of TDFs. Finally, we employed L17E-coated TDF to deliver osteogenic growth peptide and demonstrated its potential applications in inhibiting periodontitis both in vitro and in vivo. This straightforward and cost-effective strategy holds promise for advancing the biomedical applications of DNA nanostructures.</p></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"3 2","pages":"Article 100098"},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773045X24000098/pdfft?md5=663ff88ef1140bb1f77c4c3c37915cd5&pid=1-s2.0-S2773045X24000098-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140091702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}