Ke Quan , Yuqing Zeng , Sijia Gao , Yanli Lei , Le Yang , Yibo Zhou , Lucky Poh Wah Goh , Zhihe Qing
{"title":"Metal-bearing nanomaterials for oral antibacteria: Mechanisms and applications","authors":"Ke Quan , Yuqing Zeng , Sijia Gao , Yanli Lei , Le Yang , Yibo Zhou , Lucky Poh Wah Goh , Zhihe Qing","doi":"10.1016/j.asems.2025.100141","DOIUrl":"10.1016/j.asems.2025.100141","url":null,"abstract":"<div><div>The prevalent oral diseases, such as dental caries, chronic gingivitis, and periodontitis, which are primarily caused by pathogenic bacteria, pose significant public health risks and impose substantial economic burdens. However, conventional treatment strategies for oral pathogens rely on mechanical debridement and antibiotic treatment, which remain unsatisfactory and contribute to the emergence of antimicrobial resistance pathogens. The escalating crisis of antibiotic resistance and the intricate microbial communities in oral niches urgently demand innovative antimicrobial strategies that can overcome these issues. Metal-bearing nanomaterials (MBNs), as an integration of metallic components with other substances such as polymers or inorganic materials, have demonstrated improved antimicrobial effectiveness while mitigating the toxicity associated with pure metals in oral environments. This review provides an innovative overview of designing and utilizing MBNs for oral antimicrobial applications, bridging the gap between nanomaterial design and clinical dentistry needs while guiding the development of next-generation antimicrobials in the post-antibiotic era. Firstly, we categorize and elucidate the main antibacterial mechanisms of metallic components in MBNs. Furthermore, a comprehensive summary is provided on the up-to-date advancements in using MBNs for oral antibacterial purposes, highlighting the pivotal role of metals in enhancing antibacterial properties. Finally, we discuss the existing challenges and potential future developments to establish a theoretical foundation for ongoing progress and clinical approval.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 2","pages":"Article 100141"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial: Recent approaches in biosensors and wearable sensors","authors":"Chengyi Xiong","doi":"10.1016/j.asems.2025.100143","DOIUrl":"10.1016/j.asems.2025.100143","url":null,"abstract":"","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 2","pages":"Article 100143"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143898761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Simple surface modification of poly(methyl methacrylate) microfluidic microplates for enhanced ultrasensitive multiplexed detection of infectious diseases","authors":"Sharma T. Sanjay , Sapna Kannan , XiuJun Li","doi":"10.1016/j.asems.2025.100142","DOIUrl":"10.1016/j.asems.2025.100142","url":null,"abstract":"<div><div>Novel strategies for the simultaneous and portable detection of multiple analytes are highly favorable for clinical diagnosis and healthcare. Conventional colorimetric enzyme-linked immunosorbent assay (ELISA) is a widely used laboratory technique for medical diagnostics, quality control, and research applications. However, nonspecific absorption of proteins may lead to a reduction of functional sites, resulting in high background and low sensitivity in ELISA. Herein, we report a simple method of functionalization of poly(methyl methacrylate) (PMMA) with polylysine to be used as the microfluidic microplate substrate for enhanced ELISA, enabling rapid, ultrasensitive, and multiplexed detection of infectious diseases. FTIR and fluorescence microscopy characterization confirmed high amine densities on polylysine-modified PMMA surface, resulting in high detection sensitivity of the colorimetric ELISA on the PMMA microdevice. The ultrasensitive polylysine-modified microplate can immobilize protein within 20 min and results of the assay can be viewed by the naked eye or scanned through a simple desktop scanner for quantitative analysis within 90 min. A sandwich-type immunoassay for the rapid and sensitive detection of immunoglobulin G (IgG), hepatitis B surface antigen (HBsAg), and hepatitis B core antigen (HBcAg) was demonstrated as a proof-of-concept for multiplexed detection. The limits of detection (LOD) of 200.0 pg/mL for IgG, 180.0 pg/mL for HBsAg, and 300.0 pg/mL for HBcAg were achieved, without any specialized equipment like a microplate reader. The surface-modified microchip exhibited about 10-fold higher sensitivity than traditional microplates. This surface-modified microplate has tremendous potential as a point-of-care multiplexed testing platform for many applications ranging from clinical diagnosis to environmental monitoring, particularly in resource-limited settings.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 2","pages":"Article 100142"},"PeriodicalIF":0.0,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143847360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kelcilene B.R. Teodoro , Tamires S. Pereira , Ana Laura M.M. Alves , Francisco V. dos Santos , Fabrício A. dos Santos , Daniel S. Correa
{"title":"3D-printed microneedles for sensing applications: Emerging topics and future trends","authors":"Kelcilene B.R. Teodoro , Tamires S. Pereira , Ana Laura M.M. Alves , Francisco V. dos Santos , Fabrício A. dos Santos , Daniel S. Correa","doi":"10.1016/j.asems.2025.100139","DOIUrl":"10.1016/j.asems.2025.100139","url":null,"abstract":"<div><div>3D-printed microneedles (MNs) have revolutionized the biomedical sector, enabling applications in aesthetic treatments, vaccine delivery, diagnostics, and real-time biomarker analysis. These minimally invasive structures advance the development of sensors and biosensors for diverse applications, including human, veterinary, agricultural, and environmental domains. Recent trends favor MNs made from polymers and nanomaterials over traditional metals, addressing challenges related to cost, biocompatibility, and scalability. In this context, this review explores recent advancements on different MNs-based sensors, fabricated by 3D printing, highlighting innovations, shortcomings and also pointing future opportunities to expand their applications in medical, agricultural and environmental domains. Initially, we discuss the general aspects of planning an efficient MN's design (encompassing possible types and required properties), as well as the choice of materials and manufacturing techniques for 3D printing polymeric MNs. Next, we examine the relationship between printing techniques, the manufactured MNs, and their integration with sensors, followed by examples of studies that explore this connection. Key innovations include the use of biodegradable resins, nanocomposites, artificial intelligence, and machine learning for design optimization. While biomedical applications dominate, we highlight significant opportunities for MNs in agriculture and environmental monitoring through tailored manufacturing approaches.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 2","pages":"Article 100139"},"PeriodicalIF":0.0,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143934927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fluorescent graphene quantum dots: Properties regulation, sensing applications, and future prospects","authors":"Ru Wu , Yue Cao , Zixuan Chen , Jun-Jie Zhu","doi":"10.1016/j.asems.2025.100140","DOIUrl":"10.1016/j.asems.2025.100140","url":null,"abstract":"<div><div>Graphene quantum dots (GQDs), as an emerging class of nascent carbon-based materials, demonstrate remarkable promise in fluorescence sensing applications. Those potentials stem from several factors, including their favorable photoluminescence (PL) characteristics, feasibility of surface functionalization, excellent biocompatibility, and low cytotoxicity. This review concentrates on the fundamental optical properties of GQDs, with specific reference to the manipulation of intrinsic characteristics both by heteroatom doping and surface/edge functionalization. These modifications permit the alteration of optical properties, thereby rendering GQDs more versatile for an array of applications. Subsequently, we then delve into the recent applications of GQDs in fluorescence sensing, encompassing both turn-off and turn-on mechanisms. Finally, it presents a systematic assessment of the current state of research on GQDs, along with discussions on challenges and prospects for expanding and improving their applications.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 3","pages":"Article 100140"},"PeriodicalIF":0.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143937791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial: DNA and inorganic nanomaterials for sensors and energy","authors":"Lihua Wang","doi":"10.1016/j.asems.2025.100138","DOIUrl":"10.1016/j.asems.2025.100138","url":null,"abstract":"","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 2","pages":"Article 100138"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143835010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdulla Alsaad, Iftikhar Ahmad, Adel Aawan, Ahmed M. Abdelrhman, Wajid Khan
{"title":"Design, development and testing of a wearable hybrid energy harvester for sustainable gadgets","authors":"Abdulla Alsaad, Iftikhar Ahmad, Adel Aawan, Ahmed M. Abdelrhman, Wajid Khan","doi":"10.1016/j.asems.2025.100137","DOIUrl":"10.1016/j.asems.2025.100137","url":null,"abstract":"<div><div>This research paper presents the design, development and testing of a novel wearable hybrid energy harvester (WH-EH) aimed at powering sustainable gadgets. By harnessing energy using both electromagnetic and piezoelectric transduction mechanisms to capture ambient mechanical energy from human body motion, this device offers a versatile solution to the growing demand for portable and renewable energy. The paper details the integration of both mechanisms into a single device that fits in human shoes and the practical implications of deploying such technology in everyday gadgets. The WH-EH comprised of 3D printed frame, a cantilever beam made up of stainless steel, two permanent neodymium magnets residing at the tip of the cantilever beam, two printed circuit board-based micro planar coils that were fixed to the top and bottom of the 3D printed frame. Through rigorous testing, the WH-EH has demonstrated significant potential of producing maximum a power of 577 μW which can help in reducing the reliance on traditional power sources and advancing the frontier of wearable technology. Energy harvesters like WH-EH are pivotal in advancing the sustainability of wearable gadgets, diminishing the dependence on traditional battery sources. These innovations not only strengthen the longevity and eco-friendliness of personal electronics but also align with global sustainable development goals, particularly in the energy and environmental sectors. The progression of such energy harvesters marks a crucial milestone in the ongoing integration of renewable energy practices into daily electrical applications.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 1","pages":"Article 100137"},"PeriodicalIF":0.0,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143454445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yitian Tang , Qunmei Zhang , Hongchang Yuan , Xiaoyin Wang , Liuyang Xu , Guoqiang Wang , Min Zhang , Ping Lu , Hua Zhong , Yihan Wang
{"title":"Recent applications and challenges of inorganic nanomaterial-based biosensing devices for detecting nucleic acid biomarkers","authors":"Yitian Tang , Qunmei Zhang , Hongchang Yuan , Xiaoyin Wang , Liuyang Xu , Guoqiang Wang , Min Zhang , Ping Lu , Hua Zhong , Yihan Wang","doi":"10.1016/j.asems.2025.100136","DOIUrl":"10.1016/j.asems.2025.100136","url":null,"abstract":"<div><div>Nucleic acids are specific biomolecules for clinically relevant diseases. Highly sensitive detection of these low-abundance biomolecules is essential for understanding their functions in disease diagnosis, prognosis, and predicting treatment effects. As a traditional detection method, polymerase chain reaction (PCR) has high sensitivity. However, it is time-consuming and requires complex experimental equipment, which limits its application in on-site rapid detection. To address these issues, biosensing devices based on inorganic nanomaterials (INMs) have been widely used to detect nucleic acid biomarkers in recent years. Compared with organic or polymer nanomaterials, INMs have unique physical and chemical properties that produce synergistic effects regarding biocompatibility, electrical conductivity, and high specific surface area. It can also amplify the signal by increasing the signal tag loading, making it ideal for biosensing devices. This article reviews the latest progress of INMs (metal nanoparticles, metal oxide nanomaterials, carbon-based nanomaterials, quantum dots, magnetic nanomaterials) in nucleic acid detection and introduces the definition, specific effects, and synthesis of INMs. Subsequently, the applications of INMs integrated into various sensing platforms were discussed, including electrochemical biosensors, electrochemiluminescence (ECL) biosensors, photoelectrochemical (PEC) biosensors, and self-powered biosensor and point-of-care testing (POCT) to achieve highly sensitive and specific detection of nucleic acid molecules such as DNA and RNA. Finally, the opportunities and challenges faced by biosensing devices based on INMs in the future development of nucleic acid detection are discussed and prospected.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 1","pages":"Article 100136"},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143444265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Min Yang , Yushi Xie , Longjiao Zhu , Ran Wang , Jie Zheng , Wentao Xu
{"title":"Aptamer-based biosensors for biogenic amines detection","authors":"Min Yang , Yushi Xie , Longjiao Zhu , Ran Wang , Jie Zheng , Wentao Xu","doi":"10.1016/j.asems.2025.100135","DOIUrl":"10.1016/j.asems.2025.100135","url":null,"abstract":"<div><div>Biogenic amines (BAs) are a class of small nitrogen-containing organic compounds commonly found in various foods and are one of the common metabolic by-products in the process of food spoilage. When consumed in excessive amounts by the human body, BAs can cause a range of adverse reactions such as difficulty in breathing and palpitations, posing a serious threat to life and health. Moreover, the content of BAs is closely related to the degree of food spoilage, making them an important indicator for measuring food quality and freshness. Therefore, accurate detection of BAs is particularly important. Aptamer biosensors are becoming more and more important in the field of biosensing and show great potential. In this review, we first systematically summarized the structural characteristics, formation mechanism and potential toxicity of BAs. Then, the screening strategies and methods of biogenic amine aptamers were discussed. On this basis, we focus on the latest progress in the field of aptamer sensor technology for BAs detection in food and divide these technologies into four categories according to the detection principle: colorimetric analysis, fluorescence detection, surface-enhanced Raman spectroscopy (SERS) analysis and electrochemical detection. Finally, the future development direction and current challenges of biogenic amine detection strategies are introduced.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 2","pages":"Article 100135"},"PeriodicalIF":0.0,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143600909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ingemar Petermann , Magnus Lindblom , Carola Sterner , Greger Gregard , Stefan Karlsson
{"title":"Optical fiber sensor solutions for in-situ transmittance control of electrochromic glazing","authors":"Ingemar Petermann , Magnus Lindblom , Carola Sterner , Greger Gregard , Stefan Karlsson","doi":"10.1016/j.asems.2025.100134","DOIUrl":"10.1016/j.asems.2025.100134","url":null,"abstract":"<div><div>Windows are essential to let natural daylight into our buildings. Smart and dynamic glazing is an important technology for achieving sustainable and energy-efficient buildings with good indoor environment by reducing the need for air-conditioning. Electrochromic glazing is the commercial state-of-the-art for smart and dynamic glazing. In principle electrochromic glazing works like a thin film battery, whose lifetime is enhanced if the combination of elevated temperature and a high state-of-charge, or low light transmittance, are avoided. Therefore, a direct transmittance measurement is desirable. In this study, we have evaluated four different methods using optical fibers, whereof two methods were found to work well, both in initial testing and when compared to reference transmittance cycling measurements. Both methods relied on light from a light emitting diode, at 810 nm wavelength, that was propagated either through the electrochromic foil or along it. The latter shows most potential to be implemented in a manufacturing process of smart glazing.</div></div>","PeriodicalId":100036,"journal":{"name":"Advanced Sensor and Energy Materials","volume":"4 1","pages":"Article 100134"},"PeriodicalIF":0.0,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143420978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}