Advanced Agrochem最新文献

{"title":"In memoriam: James Nicholas Seiber (1940–2023)","authors":"Yang Guang-Fu","doi":"10.1016/j.aac.2023.08.005","DOIUrl":"10.1016/j.aac.2023.08.005","url":null,"abstract":"","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"2 4","pages":"Page 297"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237123000606/pdfft?md5=db439ba1cc38bd553b5c1067aa6f32cb&pid=1-s2.0-S2773237123000606-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136222032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel quinoxalinone-1,2,3-triazole derivatives as potential antifungal agents for plant anthrax disease: Design, synthesis, antifungal activity and SAR study","authors":"","doi":"10.1016/j.aac.2023.11.003","DOIUrl":"10.1016/j.aac.2023.11.003","url":null,"abstract":"<div><p>A series of quinoxalinone-1,2,3-triazole derivatives have been synthesized and tested for antifungal activity against phytopathogenic fungus through mycelial growth inhibition in <em>vitro</em>, spore germination inhibition in <em>vitro</em> and control effect in <em>vivo</em>. The results showed that the pharmacophore quinoxalinone and 1,2,3-triazole displayed promising antifungal activity. The EC50 value against <em>C. gloeosporioides</em> of 6a-1 was 1.17 μg/mL and the compound 6c-1 showed the good bioactivity against <em>C. fragariae Brooks</em> and <em>P. oryzae Cav.,</em> displaying EC50 values of 5.56, 4.62 μg/mL, respectively. The inhibitory of spore germination by 6a-1 was performed with EC50 value of 1.91 μg/mL. In addition, the in <em>vivo</em> bioassay indicated that 6a-1 possessed effective control against Pepper Anthrax Disease in protective treatment. For given activity data of target compounds, structure-activity relationship (SAR) study was operated, hoping for optimizing the target structure to find lead compound with higher activity.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"3 3","pages":"Pages 222-228"},"PeriodicalIF":0.0,"publicationDate":"2023-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237123000965/pdfft?md5=7df8642ee3cc767ea1f5fc965e9add9a&pid=1-s2.0-S2773237123000965-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139303921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new binding mode for ecdysteroid analog tebufenozide as a multitargeted IGR with chitinase","authors":"","doi":"10.1016/j.aac.2023.11.006","DOIUrl":"10.1016/j.aac.2023.11.006","url":null,"abstract":"<div><p>Tebufenozide, an efficient insect growth regulator (IGR) against lepidopteran pests, presents a novel mode of action with minimal non-target impact. By competing with ecdysteroids for ecdysone receptor (EcR) binding, it regulates insect growth precisely. This study explores tebufenozide's potential as a multitarget IGR, targeting both EcR and <em>Ostrinia furnacalis</em> chitinase I (<em>Of</em>ChtI). The inhibitory activity against <em>Of</em>ChtI is comparable to that of substrates (GlcNAc)₅, with an IC₅₀ of 45.77 ​μM. Our computational findings indicate that tebufenozide binds at the subsite −1 to +1 of <em>Of</em>ChtI through various interactions. Notably, tebufenozide establishes a pi-pi interaction with the flipped sidechain of Trp107, enabling tebufenozide to deeply penetrate into the S1 pocket, thereby obstructing substrate binding to <em>Of</em>ChtI. These insights highlight the potency of multitarget strategies, laying the groundwork for innovative IGR designs that offer comprehensive pest management solutions.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"3 3","pages":"Pages 229-236"},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237123000990/pdfft?md5=f82031eab2e4c395013f816903ce225e&pid=1-s2.0-S2773237123000990-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139301598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smart agriculture and nanotechnology: Technology, challenges, and new perspective","authors":"Shivani Garg ,&nbsp;Nelson Pynadathu Rumjit ,&nbsp;Swapnila Roy","doi":"10.1016/j.aac.2023.11.001","DOIUrl":"10.1016/j.aac.2023.11.001","url":null,"abstract":"<div><p>In the recent past, much nanotechnology research has been done in an effort to increase agricultural productivity. The Green Revolution led to the careless use of pesticides and artificial fertilizers, which reduced soil biodiversity and led to the development of disease and insect resistance. This article highlights the worldwide development and status of precision agriculture. Precision agriculture utilizes technologies and principles to manage spatial and temporal variability in agricultural production to improve crop performance and environmental quality. In precision agriculture (PA), information technology (IT) is used to make sure that crops and soil receive exactly what they require for optimal productivity and health. Precision farming includes the use of hardware i.e., a global positioning system (GPS) and geographic information system (GIS), different software of GIS, and traditional knowledge of agriculture management practices. The benefits of precision agriculture can be seen in both the economic and environmental aspects of agricultural production. Only nanoparticles or nanochips can transport materials to plants in a nanoparticle-mediated manner and create sophisticated biosensors for precision farming. Conventional fertilizers, insecticides, and herbicides can be nano encapsulated to provide exact doses to plants through a gradual, continuous release of nutrients and agrochemicals. The main topics included in this article are the variability of natural resources, variability management; administrative districts; the impact of precision farming technologies on farm profitability and the environment; innovations in sensors, controls, and remote sensing, information management; trends in global application and acceptance of precision farming technologies; potential and possibilities of technology along with challenges in agricultural modernization. Modern equipment and procedures based on nanotechnology have the ability to solve many of the issues in conventional agriculture and might transform this industry. There are many challenges in the implementation of smart agriculture equipment and approaches in the field as this technique uses both hardware and software. The cost of labour for managing IoT devices and the cost-of-service registration are included in the system operational cost. Additionally, there are operating costs related to the use of energy, maintenance, and communication between IoT devices, gateways, and cloud servers. In this review, nanotechnology is explored as a potential tool in precision agriculture, as well as the advantages of nanoparticles in agriculture, such as the use of fertilizers. By using precision agriculture, the food production chain can be monitored and quality and quantity can be managed effectively.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"3 2","pages":"Pages 115-125"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237123000825/pdfft?md5=210709003a14ac4686c89c24eaed6fc1&pid=1-s2.0-S2773237123000825-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135566735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A timing self-cleaning nanoherbicide: Design of triple-structure nanovectors for weed control and pesticide residues treatment","authors":"Jiao Cheng ,&nbsp;Mei Li ,&nbsp;Ri-xin Zhu ,&nbsp;Jing-yi Li ,&nbsp;Jun Yin ,&nbsp;Wang Xiao","doi":"10.1016/j.aac.2023.10.002","DOIUrl":"10.1016/j.aac.2023.10.002","url":null,"abstract":"<div><div>Pesticide residues treatment is a crucial issue for both agricultural production and environmental protection. In recent years, designing self-cleaning nanoformulations has emerged as a promising strategy for reducing pesticide residues in a convenient and cost-effective manner. However, traditional physical blending methods of photodegradation reagents with nanocarriers have limitations in terms of pesticide residue degradation efficiency and active ingredient efficacy. Here, a new type of timing self-cleaning nanoherbicide dicamba@mSiO₂/ATA/TiO₂ with a triple structure was fabricated. Dicamba, a widely used herbicide that was attracting increasing concern over its high efficiency and broad spectrum, was selected as the model herbicide and loaded on the mSiO₂ shell. In the stage of pesticide release, the TiO₂ and dicamba were separated by the timing-barrier. Therefore, the efficacy of dicamba was not affected by the photocatalyst. During the release process, the ATA layer continuously absorbed the reactive oxygen species (ROS) produced by TiO₂ and was gradually degraded. Finally, the barrier was destroyed, and the residual dicamba in the carrier was degraded by TiO₂. Compared with the traditional physical blending method, this triple structure avoided the degradation of active ingredients by photocatalysts during the pesticide release period. The experimental results suggested that this nanoformulation improved the efficacy of the herbicide, and reduced the pesticide residues, providing a new approach for self-cleaning nanopesticides research.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"3 4","pages":"Pages 298-307"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136093699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional nucleic acids with synthetic sugar or nucleobase moieties","authors":"Ze Zhang ,&nbsp;Siqi Chen ,&nbsp;Zhe Li ,&nbsp;Hanyang Yu","doi":"10.1016/j.aac.2023.08.001","DOIUrl":"https://doi.org/10.1016/j.aac.2023.08.001","url":null,"abstract":"<div><p>Functional nucleic acids including aptamers and DNAzymes are a class of valuable molecular tool for biotechnology. However, DNA and RNA aptamers and catalysts suffer from low biological stability and limited chemical diversity. Xeno-nucleic acids (XNAs) refer to nucleic acid analogues containing sugar moieties that are structurally distinct from DNA and RNA and possess advantageous properties. In this article, we first focus on two types of XNAs, threose nucleic acid (TNA) and 2’-fluoroarabinose nucleic acid (FANA), and summarize recent <em>in vitro</em> selections of TNA and FANA aptamers and catalysts. We then review three classes of unnatural base pairs (UBPs) and highlight examples of UBP-containing DNA aptamers and DNAzymes. Lastly, we briefly describe an XNA-modified DNAzyme 10–23 (X10-23) and its application in RNA knockdown and virus detection. Functional XNAs provide important chemical biology tools for biomedical research and future interdisciplinary collaboration will boost XNA basic research and clinical translation.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"2 3","pages":"Pages 236-245"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49712399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colorimetric and electrochemical dual-signal detection of uracil-DNA glycosylase using functionalized pure DNA hydrogel on paper-based analytical devices","authors":"Wei Xue ,&nbsp;Pan Jia ,&nbsp;Yunping Wu ,&nbsp;Pu Wang ,&nbsp;Jiarong Shi ,&nbsp;Yangyang Chang ,&nbsp;Meng Liu","doi":"10.1016/j.aac.2023.06.007","DOIUrl":"https://doi.org/10.1016/j.aac.2023.06.007","url":null,"abstract":"<div><p>The development of simple and accurate detection of uracil-DNA glycosylase (UDG) is of great significance for early clinical diagnosis and biomedical research. Here, we on the first effort introduced the uracil bases into the rolling circle amplification (RCA) reaction to produce the functionalized pure DNA hydrogel (PDH) for UDG detection. During RCA process, methylene blue (MB) molecules as the indicators were encapsulated into PDH. The addition of UDG can remove the uracil bases of PDH to generate abasic sites, which are further cleaved with the assistance of apurinic/apyrimidinic endonuclease (APE), thus resulting in the dissociation of PDH to release blue MB. By combining with the paper analytical devices as the signal readout platform, a colorimetric and electrochemical dual-signal biosensor was constructed for convenient and accurate detection of UDG. The proposed MB@PDH-based dual-signal sensing system exhibited good selectivity and high sensitivity with a detection limit of 6.4 × 10⁻⁴ U/mL (electrochemical method). It was also demonstrated that this sensing system showed excellent performance in UDG inhibitor screening, thus providing great potential in UDG-related disease diagnosis and drug discovery.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"2 3","pages":"Pages 269-275"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49712663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Wentao Xu,&nbsp;Longjiao Zhu,&nbsp;Yifan Wu,&nbsp;Shenghao Lin","doi":"10.1016/j.aac.2023.06.003","DOIUrl":"https://doi.org/10.1016/j.aac.2023.06.003","url":null,"abstract":"","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"2 3","pages":"Pages 200-201"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49712541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large SYBR Green I fluorescence enhancement for label-free aptamer-based detection of estradiol","authors":"Xiaoqin Wang,&nbsp;Jiawen Liu,&nbsp;Chenqi Niu,&nbsp;Juewen Liu","doi":"10.1016/j.aac.2023.04.003","DOIUrl":"https://doi.org/10.1016/j.aac.2023.04.003","url":null,"abstract":"<div><p>Estradiol (E2) and related estrogens are emerging environmental contaminants that may adversely affect the health of humans, animals, and ecosystems. Many aptamers have been reported for the detection of E2, and our lab recently selected a series of high-affinity and short DNA aptamers that showed various binding orientations to E2, leading to different selectivity patterns. In this work, we report that using SYBR Green I (SGI) as a fluorescence probe, up to 200% fluorescence increase was achieved upon titration of E2 to these aptamers. Such enhancement was the highest among all reported small molecule binding aptamers using SGI for signal generation, although some metal-binding DNA can achieve even higher enhancement. By gradually shortening the stem region of an E2 binding aptamer, we concluded that the enhanced fluorescence was from the aptamer binding pocket upon target binding instead of from the duplexed stem region. Comparison was also made with a few other aptamers including those for caffeine, quinine, uric acid and cortisol, and none of them showed more than 20% fluorescence change. Using the SGI method, the detection limit was calculated to be 2.4 nM E2. We attributed the large fluorescence enhancement to the hydrophobic nature of E2 and the high-affinity binding of the aptamers. This study provides insights into the aptamers that can use SGI for their binding assays and biosensor development.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"2 3","pages":"Pages 258-263"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49712660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding research and development of functional nucleic acids for agricultural applications","authors":"Yingfu Li","doi":"10.1016/j.aac.2023.08.007","DOIUrl":"https://doi.org/10.1016/j.aac.2023.08.007","url":null,"abstract":"","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"2 3","pages":"Pages 197-199"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49761724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}