Advanced Agrochem最新文献_第10页

Recent progress in encapsulation and controlled release of pesticides based on cyclodextrin derivative carriers 环糊精衍生物载体农药包封控释研究进展

Advanced Agrochem Pub Date : 2022-12-01 DOI: 10.1016/j.aac.2022.11.008

Zhisheng Liu , Weiwei Xu , Elena G. Kovaleva , Jing Cheng , Haibing Li

{"title":"Recent progress in encapsulation and controlled release of pesticides based on cyclodextrin derivative carriers","authors":"Zhisheng Liu , Weiwei Xu , Elena G. Kovaleva , Jing Cheng , Haibing Li","doi":"10.1016/j.aac.2022.11.008","DOIUrl":"10.1016/j.aac.2022.11.008","url":null,"abstract":"<div><p>In the context of the continuous increase in global grain production, accompanied by a large amount of investment in various pesticides, herbicides, fungicides, and other chemical pesticides. It has caused inevitable environmental problems and food safety problems. Current research suggests that the use of cyclodextrins and their derivatives to protect pesticides can significantly reduce the number of agrochemicals that pollute the environment. Using the cavity properties of cyclodextrins, we can refer to the similar way in which drug molecules make cyclodextrins and cyclodextrin polymers to form inclusion compounds. Overall, β-cyclodextrin and its derivatives are used as a new pesticide excipient to improve the stability of pesticides, prevent their oxidation and decomposition, improve the solubility and bioavailability of pesticides, reduce the toxic side effects of drugs, and mask the odour of drugs. In this review, we focus on summarising the recent research progress of β-cyclodextrins and their derivatives in pesticides and other fields, and provide a systematic classification of β-cyclodextrin polymers, as well as new synthesis methods and techniques in various applications. Finally, the future development of cyclodextrin-like polymers is foreseen, and issues arising from the research are discussed and addressed in depth.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"1 2","pages":"Pages 89-99"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237122000296/pdfft?md5=b7a1089a6956f6d5899cb926433b5d17&pid=1-s2.0-S2773237122000296-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73265059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Challenges and risks associated with impurity profiles in technical grade crop protection products produced semi-synthetically from natural products 在由天然产品半合成生产的技术级作物保护产品中与杂质相关的挑战和风险

Advanced Agrochem Pub Date : 2022-12-01 DOI: 10.1016/j.aac.2022.11.009

Peter Maienfisch

{"title":"Challenges and risks associated with impurity profiles in technical grade crop protection products produced semi-synthetically from natural products","authors":"Peter Maienfisch","doi":"10.1016/j.aac.2022.11.009","DOIUrl":"10.1016/j.aac.2022.11.009","url":null,"abstract":"<div><p>The safety of crop protection products and their safe use is of paramount importance and requires that crop protection products are consistently marketed and used worldwide in the required registered quality. To meet these high-quality requirements, the highest demands must be placed on the production and purification of technical-grade crop protection products. In this context, impurity profiles are of utmost importance, as unknown impurities at higher than registered concentrations may pose new unknown toxicological risks to users, consumers, and the environment. Particularly high demands are placed on the production and purification of technical grade semisynthetic derivatives of fermentatively derived natural products to meet the required regulatory specifications, to ensure that relevant impurities do not exceed maximum allowable concentrations, to ensure the safe use of such products, and to eliminate any unknown product safety risks. The challenges associated with the manufacture and purification of Afidopyropen and the product safety risks associated with various qualities of technical grade Emamectin benzoate are discussed in detail.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"1 2","pages":"Pages 148-156"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237122000302/pdfft?md5=d0eb79a09e241eda2eecd1faf3d6100a&pid=1-s2.0-S2773237122000302-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78265555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Structural insights of 4-Hydrophenylpyruvate dioxygenase inhibition by structurally diverse small molecules 结构多样的小分子抑制4-氢苯基丙酮酸双加氧酶的结构见解

Advanced Agrochem Pub Date : 2022-12-01 DOI: 10.1016/j.aac.2022.10.002

Jin Dong , Jiangqing Dong , Xin-He Yu, Yao-Chao Yan, Jia-Xu Nan, Bo He, Bao-Qin Ye, Wen-Chao Yang, Hong-Yan Lin, Guang-Fu Yang

{"title":"Structural insights of 4-Hydrophenylpyruvate dioxygenase inhibition by structurally diverse small molecules","authors":"Jin Dong , Jiangqing Dong , Xin-He Yu, Yao-Chao Yan, Jia-Xu Nan, Bo He, Bao-Qin Ye, Wen-Chao Yang, Hong-Yan Lin, Guang-Fu Yang","doi":"10.1016/j.aac.2022.10.002","DOIUrl":"https://doi.org/10.1016/j.aac.2022.10.002","url":null,"abstract":"<div><p>4-Hydrophenylpyruvate dioxygenase (HPPD), a key enzyme involved in tyrosine catabolism, has long been considered a promising target for herbicides and drugs. Several types of HPPD inhibitors have been developed as high-potency drugs or herbicides. Understanding the structural basis of the binding of these inhibitors with HPPD will be beneficial for the development of inhibitors containing novel scaffolds. However, only limited structural information regarding the binding of triketone and pyrazole derivatives with HPPD has been reported. Here, the crystal structures of HPPD complexed with inhibitors containing different scaffolds, including triketone, pyrazole, isoxazole, heterocyclic amide, and quinazolindione derivatives, were comprehensively analyzed. Detailed binding modes of isoxazole and heterocyclic amide derivatives with HPPD were first revealed, facilitating further structural optimization. The binding mode of compound <strong>2</strong> with HPPD suggests that both oxygen and nitrogen atoms can mediate coordination with the metal ion. These results will provide the structure-based rational design of novel HPPD inhibitors.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"1 2","pages":"Pages 174-181"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237122000211/pdfft?md5=408308a7ed77e0f5aff3f3dceea5a0e1&pid=1-s2.0-S2773237122000211-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91724870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trends and perspectives on general Pesticide analytical chemistry 农药一般分析化学的发展趋势与展望

Advanced Agrochem Pub Date : 2022-12-01 DOI: 10.1016/j.aac.2022.11.002

Yangliu Wu , Lijun Han , Xuemin Wu , Wayne Jiang , Hui Liao , Zhi Xu , Canping Pan

{"title":"Trends and perspectives on general Pesticide analytical chemistry","authors":"Yangliu Wu , Lijun Han , Xuemin Wu , Wayne Jiang , Hui Liao , Zhi Xu , Canping Pan","doi":"10.1016/j.aac.2022.11.002","DOIUrl":"10.1016/j.aac.2022.11.002","url":null,"abstract":"<div><p>Agrochemicals are indispensable materials in agricultural production, used to control or prevent diseases, insects and weeds, and play important roles in ensuring both food security and food safety. Meanwhile, the negative impacts of modern synthetic pesticides on humans and the environment could not be neglected. Thus, the production, registration, application and monitoring of pesticides should be strictly checked to ensure their commercial product quality and safety to human health as well as to the environment. This review summarizes the analytical chemistry involved in the quality control (QC) analysis for commercial formulation, residue analysis, dietary risk assessment and regulation prospects of pesticides. The main concepts and contents of pesticide analytical chemistry are comprehensively introduced and analyzed. In addition, the requirements and criteria of the relevant guidelines from various organizations are discussed. Finally, the research frontier areas and future trending for the invention of new generation of agrochemicals, registration/enforcement, market monitoring and risk management of pesticides are discussed.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"1 2","pages":"Pages 113-124"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237122000235/pdfft?md5=5f61c2b45ad5a3a0afc3f99b9e0a7694&pid=1-s2.0-S2773237122000235-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77948390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Development of bi-oligo (ethylene glycol)-functionalized fluorescent probe for two-photon and noninvasive imaging in Arabidopsis thaliana 拟南芥双光子无创成像双低聚乙二醇功能化荧光探针的研制

Advanced Agrochem Pub Date : 2022-12-01 DOI: 10.1016/j.aac.2022.11.003

Jingzhi Du , Keming Chen , Zhenyang Yu , Yuhao Qiao , Jiaxin Liu , Qianqian Zhai , Zhe Hu , Sheng-Gang Yang , Jun Li , Huailong Teng

{"title":"Development of bi-oligo (ethylene glycol)-functionalized fluorescent probe for two-photon and noninvasive imaging in Arabidopsis thaliana","authors":"Jingzhi Du , Keming Chen , Zhenyang Yu , Yuhao Qiao , Jiaxin Liu , Qianqian Zhai , Zhe Hu , Sheng-Gang Yang , Jun Li , Huailong Teng","doi":"10.1016/j.aac.2022.11.003","DOIUrl":"https://doi.org/10.1016/j.aac.2022.11.003","url":null,"abstract":"<div><p>Fluorescent probe is an important tool for investigation of biological events in plant tissues. However, the research on small-molecule based fluorescent probe for plant imaging still stays at the initial stage. In order to noninvasively achieve the subcellular information of <em>Arabidopsis thaliana</em>, a two-photon and fluorene based fluorophore with a bi-oligo (ethylene glycol) functional group was synthesized. Under the laser's irradiation at 750 nm, the subcellular structures of <em>Arabidopsis thaliana</em> including stomata and root tips were clearly observed without slicing, which displayed significant superiorities over traditional single-photon excitation microscopy. Subsequently, the above functionalized fluorophore was further modified with a recognition group (dipicolylamine) to form a smart fluorescent probe (<strong>LJTP1</strong>). As results, <strong>LJTP1</strong> not only can sensitively detect Cu<sup>2+</sup>/S<sup>2−</sup> with fluorescence “on-off-on” response <em>in vitro</em> and <em>in vivo</em>, but also can achieve noninvasive imaging in <em>Arabidopsis thaliana</em> tissues under two-photon microscopy. We believe this study will open up a new mind for noninvasive imaging in plant tissues.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"1 2","pages":"Pages 162-173"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237122000247/pdfft?md5=06f149f555228b33109813b0816f1eb0&pid=1-s2.0-S2773237122000247-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90028233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Design, synthesis and insecticidal evaluation of phthalic diamide analogs containing maleic diamide structures 含马来二胺结构邻苯二胺类似物的设计、合成及杀虫评价

Advanced Agrochem Pub Date : 2022-12-01 DOI: 10.1016/j.aac.2022.11.005

Xiwen Pang, Li Han, Cong Zhou, Xiaoyong Xu, Zhong Li

引用次数: 5

Pesticide informatics expands the opportunity for structure-based molecular design and optimization 农药信息学扩展了基于结构的分子设计和优化的机会

Advanced Agrochem Pub Date : 2022-12-01 DOI: 10.1016/j.aac.2022.11.006

Wei Zhao , Yuan-qin Huang , Ge-Fei Hao

引用次数: 8

Research progress of avermectin: A minireview based on the structural derivatization of avermectin 阿维菌素的研究进展:基于阿维菌素结构衍生化的综述

Advanced Agrochem Pub Date : 2022-12-01 DOI: 10.1016/j.aac.2022.11.001

Lili Dong , Jianjun Zhang

{"title":"Research progress of avermectin: A minireview based on the structural derivatization of avermectin","authors":"Lili Dong , Jianjun Zhang","doi":"10.1016/j.aac.2022.11.001","DOIUrl":"10.1016/j.aac.2022.11.001","url":null,"abstract":"<div><p>Avermectins, a fermentation-derived macrocyclic lactones isolated from <em>Streptomyces avermitilis,</em> exhibiting a long history as biopharmaceuticals used in agriculture, medical and veterinary fields. Due to the significant biological activity and low mammalian toxicity, avermectins have been recognized as one of the most market-competitive anthelmintics and insecticides, with research related to these compounds has been awarded the 2015 Nobel Prize in Physiology or Medicine. Avermectin molecules contain multiple reaction sites, such as carbon-carbon double bonds, hydroxyl groups and oleandrose, facilitating the further development of derivatives with improved physicochemical properties, bioavailability, pest spectrum, and efficacy by chemical modification. Presently, thousands of avermectin derivatives have been studied and various species have been commercialized for crop protection and pharmaceutical use. Herein, we review the research progress achieved on structural modification reactions of avermectin and further summarize their structure-activity relationships. This mini-review may provide important insights into the future development of efficient avermectin-based anthelmintics, fungicides, and insecticides.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"1 2","pages":"Pages 100-112"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237122000223/pdfft?md5=f73a8014681c7d5c5b036880d574e816&pid=1-s2.0-S2773237122000223-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90068228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Chitin synthase: A potential agricultural and therapeutic target 几丁质合成酶:一个潜在的农业和治疗靶点

Advanced Agrochem Pub Date : 2022-12-01 DOI: 10.1016/j.aac.2022.11.007

Ying Ye, Ze-Wei Guan, Xiao-Lei Zhu, Guang-Fu Yang

引用次数: 3

Palladium-catalyzed cross-couplings in the synthesis of agrochemicals 钯催化交偶联在农用化学品合成中的应用

Advanced Agrochem Pub Date : 2022-12-01 DOI: 10.1016/j.aac.2022.11.004

Yuxin Zhu , Wenfeng Dong , Wenjun Tang

引用次数: 4