Advanced Agrochem最新文献

{"title":"A fluorescent probe based on BODIPY for hydrogen sulfide imaging in living cells and zebrafish","authors":"Xiaolong Ding ,&nbsp;Qi Wang ,&nbsp;Degen Chen ,&nbsp;Yiliang Chen ,&nbsp;Wenwen Pan ,&nbsp;Qi Sun ,&nbsp;Qian Chen ,&nbsp;Xinya Han","doi":"10.1016/j.aac.2023.08.002","DOIUrl":"10.1016/j.aac.2023.08.002","url":null,"abstract":"<div><p>A novel fluorescent probe based on 4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) structure as fluorophore with 7-nitro-1,2,3-benzoxadiazole (NBD) served as detection unit was designed for specific and sensitive detection of H₂S in living cells and zebrafish. In this work, we prepared a novel fluorescent probe for detection of hydrogen sulfide with strong fluorescent enhancement, good biocompatible and excellent specifically detection. The probe <strong>1</strong> displayed emission at 580 nm with excited wavelength at 530 nm in aqueous solution which organic proportion was only 10%. This probe exhibits highly selectively and specifically to detect H₂S compared with other related interferences including sulphur-amino acids, sulfite ion and cations. In the addition of H₂S into the detection system, the fluorescent intensity was sharply increased about 170-fold with the limitation detection as low as 16.8 nM. The sensing mechanism was through the cleave reaction between analyte and NBD unit which was characterized by high resolution mass spectrum (HRMS). This platform also permits low biotoxicity which can successfully be utilized to evaluate the concentration level of H₂S and imaging in living cells and zebrafish.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"2 4","pages":"Pages 364-370"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237123000576/pdfft?md5=b2e16bf04b563566e4b842c9f66f08a6&pid=1-s2.0-S2773237123000576-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83569625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agarose hydrogel doped with soluble Se-chitosan for Se-enriched cultivation of sprouts","authors":"Yun Wang ,&nbsp;Wei Yang ,&nbsp;Jian Zhu ,&nbsp;Qifei Chen ,&nbsp;Na Li","doi":"10.1016/j.aac.2023.09.001","DOIUrl":"10.1016/j.aac.2023.09.001","url":null,"abstract":"<div><p>Se-chitosan with a high Se content of 139 mg/g was successfully synthesized using the glacial acetic acid-sodium selenite (HAc-Na₂SeO₃) method. The chemical structure of Se-chitosan was characterized by FTIR, XRD, TGA, UV–vis and ¹³C NMR, confirming that selenite acid was introduced into chitosan via the esterification reaction of the hydroxyl group at C6 and the electrostatic interaction of the amino group at C2 of chitosan. Agarose hydrogels were designed as an efficient carrier of Se-chitosan for Se-enriched cultivation of sprouts. The hydrogels exhibited a porous structure, which is beneficial for Se diffusion in hydrogels. The growth indexes of sprouts grown in Agar/Se-chitosan composite hydrogels with different Se concentrations, including plant weight, plant height and Se content, were investigated. The results showed that in the Se-enriched cultivation of sprouts, Se-chitosan possessed an excellent Se enrichment effect. As the Se concentration in Agar/Se-chitosan composite hydrogels increases from 0 to 1600 μg/L, the Se content of the sprouts will also increase from 0.92 mg/kg to 6.79 mg/kg accordingly. Moreover, it is necessary to control the amount of Se-chitosan added to the hydrogels; otherwise, the growth of sprouts will be inhibited. This research provided a simple and effective method for the fabrication of Se-containing hydrogels for Se-enriched cultivation of sprouts.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"2 4","pages":"Pages 356-363"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S277323712300076X/pdfft?md5=f64faab7ec353a7a35e01b7e47867192&pid=1-s2.0-S277323712300076X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84540986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploiting natural products to discover multitarget inhibitors of insect chitinolytic enzymes","authors":"Yi Ding ,&nbsp;Qiong Lu ,&nbsp;Tian Liu ,&nbsp;Qing Yang","doi":"10.1016/j.aac.2023.07.007","DOIUrl":"10.1016/j.aac.2023.07.007","url":null,"abstract":"<div><p>Multitarget insecticides are more likely to achieve comprehensive regulation of insects with a low risk of resistance. Insect chitinolytic enzymes, including GH18 chitinases and GH20 β-<em>N</em>-acetyl-<span>d</span>-hexosaminidase, are attractive targets for multitarget insecticide design by virtue of their similar substrate binding mode and catalytic mechanism. On the other hand, natural products with diverse skeletal structures are potential repositories of chitinolytic enzyme inhibitors. This minireview first presents the theoretical basis of developing multitargeted inhibitors against insect chitinolytic enzymes and then focuses on the progress in developing multitarget inhibitors derived from natural products. These may provide ideas for the exploitation of novel pesticide leads from natural products by targeting multiple targets.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"2 4","pages":"Pages 306-312"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237123000540/pdfft?md5=771e2f75e7f62634545da94cb8afbc82&pid=1-s2.0-S2773237123000540-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79239404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent advances in the natural products-based lead discovery for new agrochemicals","authors":"Pei Zhang ,&nbsp;Chun-Bao Duan ,&nbsp;Bing Jin ,&nbsp;Abdallah S. Ali ,&nbsp;Xinya Han ,&nbsp;Haifeng Zhang ,&nbsp;Ming-Zhi Zhang ,&nbsp;Wei-Hua Zhang ,&nbsp;Yu-Cheng Gu","doi":"10.1016/j.aac.2023.09.004","DOIUrl":"10.1016/j.aac.2023.09.004","url":null,"abstract":"<div><p>Crops will be harmed by fungi, pests and weeds during their growth. In the past half century, scientists have conducted in-depth research on natural products extracted from microorganisms, plants or animals, and used natural products and their derivatives as the lead for pesticides discovery. Natural product pesticides have the advantages of easy degradation in the environment, selective control and safety to non-target organisms. This review summarizes the studies on natural products pesticides in recent years, including natural products of chemical modification and biosynthesis, mainly fungicides, herbicides, insecticides and acaricides. We classify natural products according to their active fragments, and discuss their effects on the control of agricultural fungi, pests and weeds. Ultimately, we found that lead discovery based on natural products has great advantages in pesticide development.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"2 4","pages":"Pages 324-339"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237123000795/pdfft?md5=b9f25096f9f6beacd9d4659fe262f1b2&pid=1-s2.0-S2773237123000795-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135889269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In memoriam: James Nicholas Seiber (1940–2023)","authors":"Yang Guang-Fu","doi":"10.1016/j.aac.2023.08.005","DOIUrl":"10.1016/j.aac.2023.08.005","url":null,"abstract":"","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"2 4","pages":"Page 297"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237123000606/pdfft?md5=db439ba1cc38bd553b5c1067aa6f32cb&pid=1-s2.0-S2773237123000606-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136222032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel quinoxalinone-1,2,3-triazole derivatives as potential antifungal agents for plant anthrax disease: Design, synthesis, antifungal activity and SAR study","authors":"","doi":"10.1016/j.aac.2023.11.003","DOIUrl":"10.1016/j.aac.2023.11.003","url":null,"abstract":"<div><p>A series of quinoxalinone-1,2,3-triazole derivatives have been synthesized and tested for antifungal activity against phytopathogenic fungus through mycelial growth inhibition in <em>vitro</em>, spore germination inhibition in <em>vitro</em> and control effect in <em>vivo</em>. The results showed that the pharmacophore quinoxalinone and 1,2,3-triazole displayed promising antifungal activity. The EC50 value against <em>C. gloeosporioides</em> of 6a-1 was 1.17 μg/mL and the compound 6c-1 showed the good bioactivity against <em>C. fragariae Brooks</em> and <em>P. oryzae Cav.,</em> displaying EC50 values of 5.56, 4.62 μg/mL, respectively. The inhibitory of spore germination by 6a-1 was performed with EC50 value of 1.91 μg/mL. In addition, the in <em>vivo</em> bioassay indicated that 6a-1 possessed effective control against Pepper Anthrax Disease in protective treatment. For given activity data of target compounds, structure-activity relationship (SAR) study was operated, hoping for optimizing the target structure to find lead compound with higher activity.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"3 3","pages":"Pages 222-228"},"PeriodicalIF":0.0,"publicationDate":"2023-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237123000965/pdfft?md5=7df8642ee3cc767ea1f5fc965e9add9a&pid=1-s2.0-S2773237123000965-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139303921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new binding mode for ecdysteroid analog tebufenozide as a multitargeted IGR with chitinase","authors":"","doi":"10.1016/j.aac.2023.11.006","DOIUrl":"10.1016/j.aac.2023.11.006","url":null,"abstract":"<div><p>Tebufenozide, an efficient insect growth regulator (IGR) against lepidopteran pests, presents a novel mode of action with minimal non-target impact. By competing with ecdysteroids for ecdysone receptor (EcR) binding, it regulates insect growth precisely. This study explores tebufenozide's potential as a multitarget IGR, targeting both EcR and <em>Ostrinia furnacalis</em> chitinase I (<em>Of</em>ChtI). The inhibitory activity against <em>Of</em>ChtI is comparable to that of substrates (GlcNAc)₅, with an IC₅₀ of 45.77 ​μM. Our computational findings indicate that tebufenozide binds at the subsite −1 to +1 of <em>Of</em>ChtI through various interactions. Notably, tebufenozide establishes a pi-pi interaction with the flipped sidechain of Trp107, enabling tebufenozide to deeply penetrate into the S1 pocket, thereby obstructing substrate binding to <em>Of</em>ChtI. These insights highlight the potency of multitarget strategies, laying the groundwork for innovative IGR designs that offer comprehensive pest management solutions.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"3 3","pages":"Pages 229-236"},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237123000990/pdfft?md5=f82031eab2e4c395013f816903ce225e&pid=1-s2.0-S2773237123000990-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139301598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smart agriculture and nanotechnology: Technology, challenges, and new perspective","authors":"Shivani Garg ,&nbsp;Nelson Pynadathu Rumjit ,&nbsp;Swapnila Roy","doi":"10.1016/j.aac.2023.11.001","DOIUrl":"10.1016/j.aac.2023.11.001","url":null,"abstract":"<div><p>In the recent past, much nanotechnology research has been done in an effort to increase agricultural productivity. The Green Revolution led to the careless use of pesticides and artificial fertilizers, which reduced soil biodiversity and led to the development of disease and insect resistance. This article highlights the worldwide development and status of precision agriculture. Precision agriculture utilizes technologies and principles to manage spatial and temporal variability in agricultural production to improve crop performance and environmental quality. In precision agriculture (PA), information technology (IT) is used to make sure that crops and soil receive exactly what they require for optimal productivity and health. Precision farming includes the use of hardware i.e., a global positioning system (GPS) and geographic information system (GIS), different software of GIS, and traditional knowledge of agriculture management practices. The benefits of precision agriculture can be seen in both the economic and environmental aspects of agricultural production. Only nanoparticles or nanochips can transport materials to plants in a nanoparticle-mediated manner and create sophisticated biosensors for precision farming. Conventional fertilizers, insecticides, and herbicides can be nano encapsulated to provide exact doses to plants through a gradual, continuous release of nutrients and agrochemicals. The main topics included in this article are the variability of natural resources, variability management; administrative districts; the impact of precision farming technologies on farm profitability and the environment; innovations in sensors, controls, and remote sensing, information management; trends in global application and acceptance of precision farming technologies; potential and possibilities of technology along with challenges in agricultural modernization. Modern equipment and procedures based on nanotechnology have the ability to solve many of the issues in conventional agriculture and might transform this industry. There are many challenges in the implementation of smart agriculture equipment and approaches in the field as this technique uses both hardware and software. The cost of labour for managing IoT devices and the cost-of-service registration are included in the system operational cost. Additionally, there are operating costs related to the use of energy, maintenance, and communication between IoT devices, gateways, and cloud servers. In this review, nanotechnology is explored as a potential tool in precision agriculture, as well as the advantages of nanoparticles in agriculture, such as the use of fertilizers. By using precision agriculture, the food production chain can be monitored and quality and quantity can be managed effectively.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"3 2","pages":"Pages 115-125"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773237123000825/pdfft?md5=210709003a14ac4686c89c24eaed6fc1&pid=1-s2.0-S2773237123000825-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135566735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A timing self-cleaning nanoherbicide: Design of triple-structure nanovectors for weed control and pesticide residues treatment","authors":"Jiao Cheng ,&nbsp;Mei Li ,&nbsp;Ri-xin Zhu ,&nbsp;Jing-yi Li ,&nbsp;Jun Yin ,&nbsp;Wang Xiao","doi":"10.1016/j.aac.2023.10.002","DOIUrl":"10.1016/j.aac.2023.10.002","url":null,"abstract":"<div><div>Pesticide residues treatment is a crucial issue for both agricultural production and environmental protection. In recent years, designing self-cleaning nanoformulations has emerged as a promising strategy for reducing pesticide residues in a convenient and cost-effective manner. However, traditional physical blending methods of photodegradation reagents with nanocarriers have limitations in terms of pesticide residue degradation efficiency and active ingredient efficacy. Here, a new type of timing self-cleaning nanoherbicide dicamba@mSiO₂/ATA/TiO₂ with a triple structure was fabricated. Dicamba, a widely used herbicide that was attracting increasing concern over its high efficiency and broad spectrum, was selected as the model herbicide and loaded on the mSiO₂ shell. In the stage of pesticide release, the TiO₂ and dicamba were separated by the timing-barrier. Therefore, the efficacy of dicamba was not affected by the photocatalyst. During the release process, the ATA layer continuously absorbed the reactive oxygen species (ROS) produced by TiO₂ and was gradually degraded. Finally, the barrier was destroyed, and the residual dicamba in the carrier was degraded by TiO₂. Compared with the traditional physical blending method, this triple structure avoided the degradation of active ingredients by photocatalysts during the pesticide release period. The experimental results suggested that this nanoformulation improved the efficacy of the herbicide, and reduced the pesticide residues, providing a new approach for self-cleaning nanopesticides research.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"3 4","pages":"Pages 298-307"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136093699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional nucleic acids with synthetic sugar or nucleobase moieties","authors":"Ze Zhang ,&nbsp;Siqi Chen ,&nbsp;Zhe Li ,&nbsp;Hanyang Yu","doi":"10.1016/j.aac.2023.08.001","DOIUrl":"https://doi.org/10.1016/j.aac.2023.08.001","url":null,"abstract":"<div><p>Functional nucleic acids including aptamers and DNAzymes are a class of valuable molecular tool for biotechnology. However, DNA and RNA aptamers and catalysts suffer from low biological stability and limited chemical diversity. Xeno-nucleic acids (XNAs) refer to nucleic acid analogues containing sugar moieties that are structurally distinct from DNA and RNA and possess advantageous properties. In this article, we first focus on two types of XNAs, threose nucleic acid (TNA) and 2’-fluoroarabinose nucleic acid (FANA), and summarize recent <em>in vitro</em> selections of TNA and FANA aptamers and catalysts. We then review three classes of unnatural base pairs (UBPs) and highlight examples of UBP-containing DNA aptamers and DNAzymes. Lastly, we briefly describe an XNA-modified DNAzyme 10–23 (X10-23) and its application in RNA knockdown and virus detection. Functional XNAs provide important chemical biology tools for biomedical research and future interdisciplinary collaboration will boost XNA basic research and clinical translation.</p></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"2 3","pages":"Pages 236-245"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49712399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}