Advanced Agrochem最新文献

Phytic acid-assisted amorphization of bone mineral for improved phosphorus fertilizer efficiency 植酸辅助骨矿物非晶化以提高磷肥效率

Advanced Agrochem Pub Date : 2026-03-01 Epub Date: 2025-06-19 DOI: 10.1016/j.aac.2025.06.004

Mengli Guo , Jiyao Zhou , Ailing Li , Fei Xia , Lei Shi , Richard A. Martin , Dong Qiu

{"title":"Phytic acid-assisted amorphization of bone mineral for improved phosphorus fertilizer efficiency","authors":"Mengli Guo , Jiyao Zhou , Ailing Li , Fei Xia , Lei Shi , Richard A. Martin , Dong Qiu","doi":"10.1016/j.aac.2025.06.004","DOIUrl":"10.1016/j.aac.2025.06.004","url":null,"abstract":"<div><div>Phosphorus plays an indispensable role in the food chain, yet phosphorus mineral resources are finite, underscoring the urgency for developing a closed-loop phosphorus economy. Although there have been advances in phosphorus recovery from various waste materials, modern agriculture still depends on adequate phosphorus supply to support plant growth. In this study, we explored the amorphization of Ox bone using phytic acid (Ox-PA), and investigated how varying treatment durations influence the resulting structure. Inductively Coupled Plasma (ICP) analysis was employed to quantify phosphate solubilization. Additionally, pot experiments were conducted to assess the phosphate efficiency of Ox-PA in comparison to untreated Ox bone and control group. The results showed that Ox-PA exhibited significantly higher phosphate solubilization (2973 ppm) than untreated counterpart (13 ppm). When used as a fertilizer, Ox-PA markedly enhanced both aboveground and belowground biomass and root development in maize plants. Moreover, it facilitated increased phosphorus uptake by the plants during their early growth stages. These findings indicate that Ox-PA not only holds significant potential for promoting agronomic sustainability but also contributes meaningfully to the establishment of a circular phosphorus economy.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 1","pages":"Pages 58-64"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147454310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design, synthesis, and biological evaluation of 2-(benzylsulfonyl)-5-(2-methoxypyridin-4-yl)-1,3,4-oxadiazole derivatives as novel herbicides 新型除草剂2-（苄基磺酰）-5-（2-甲氧基吡啶-4-基）-1,3,4-恶二唑衍生物的设计、合成及生物学评价

Advanced Agrochem Pub Date : 2026-03-01 Epub Date: 2025-05-13 DOI: 10.1016/j.aac.2025.05.001

Sheng Yan , Chujian Ma , Lamei Wu , Changsheng Ma , Yingying Wang , Dingfeng Luo , Zuren Li , Zhijun Dai

{"title":"Design, synthesis, and biological evaluation of 2-(benzylsulfonyl)-5-(2-methoxypyridin-4-yl)-1,3,4-oxadiazole derivatives as novel herbicides","authors":"Sheng Yan , Chujian Ma , Lamei Wu , Changsheng Ma , Yingying Wang , Dingfeng Luo , Zuren Li , Zhijun Dai","doi":"10.1016/j.aac.2025.05.001","DOIUrl":"10.1016/j.aac.2025.05.001","url":null,"abstract":"<div><div>To develop herbicides with a novel mechanism of action, a series of 1,3,4-oxadiazolpyridine derivatives were designed and synthesized based on active substructure splicing and structure optimization. These derivatives <strong>(5aa</strong>-<strong>5bd</strong>) were characterized by their melting points, <sup>1</sup>H and <sup>13</sup>C nuclear magnetic resonance spectroscopy, and high-resolution mass spectrometry. The configuration of <strong>5 al</strong> was determined using single-crystal X-ray diffraction. Additionally, 5 al exhibited excellent herbicidal activity at a dosage of 75 g/hm<sup>2</sup>, showing an EC<sub>50</sub> of 4.03 g/hm<sup>2</sup> against both E. crus-galli and quinclorac-resistant E. crus-galli. At a dosage of 375 g/hm<sup>2</sup>, <strong>5 al</strong> was safe for application on rice and sorghum and showed low toxicity (>200 μg/g) towards <em>Apis mellifera</em>. After treatment with <strong>5 al</strong>, the lamellae of the chloroplast grana of barnyard grass leaves were stacked disorderly and arranged loosely, and some thylakoids were broken, as observed by transmission electron microscopy. Transcriptomics analysis of <em>E. crus-galli</em> revealed that <strong>5 al</strong> affects the defense response, membranes, plasma membranes, and chloroplasts of differentially expressed genes, which alter membrane permeability and energy metabolism, potentially leading to plant death. Thus, we successfully developed a novel molecular scaffold with a new mechanism of action that exhibits herbicidal activity against resistant <em>E. crus-galli</em>. Therefore, further development of lead herbicides based on this scaffold is required.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 1","pages":"Pages 25-32"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147332984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Peroxisome-mitochondria contact-mediated ROS transfer: A key line of defence under plant stress 过氧化物酶体-线粒体接触介导的活性氧转移：植物胁迫下的关键防线

Advanced Agrochem Pub Date : 2026-03-01 Epub Date: 2025-12-05 DOI: 10.1016/j.aac.2025.11.002

Jia Song, Zhijie Gao, Hongliang Xu

引用次数: 0

Directed evolution of HIS1-Like proteins to enhance herbicide metabolism in crops 促进作物除草剂代谢的his1样蛋白定向进化

Advanced Agrochem Pub Date : 2026-03-01 Epub Date: 2025-06-03 DOI: 10.1016/j.aac.2025.05.005

Jian Wu , Xun Wen , Xin-Long Wang , Yan-Mei Ni , Yuan-Guang Jiang , Hai-Yan Song , Kandegama Wishwajith , Qiong Chen , Hong-Yan Lin

{"title":"Directed evolution of HIS1-Like proteins to enhance herbicide metabolism in crops","authors":"Jian Wu , Xun Wen , Xin-Long Wang , Yan-Mei Ni , Yuan-Guang Jiang , Hai-Yan Song , Kandegama Wishwajith , Qiong Chen , Hong-Yan Lin","doi":"10.1016/j.aac.2025.05.005","DOIUrl":"10.1016/j.aac.2025.05.005","url":null,"abstract":"<div><div>HPPD (4-hydroxyphenylpyruvate dioxygenase) inhibitor are widely used in agriculture due to their high efficacy and environmental friendliness. However, many important crops, such as rice, wheat, and soybean, are naturally sensitive to these herbicides. In this study, we employed a directed evolution strategy to enhance the metabolic capacity of <em>Os</em>HSL2, <em>Os</em>HSL4, <em>Os</em>HSL6, and <em>Sb</em>HSL1 proteins toward HPPD inhibitors, providing a new technological approach as well as theoretical foundation for molecular breeding of herbicide-resistant crops. By combining AlphaFold 3 protein models with crystal structures, we systematically redesigned key residues to resemble the active residues found in HIS1. Catalytic activity assays demonstrated that specific mutations significantly improved the metabolic activity of HSLs proteins toward various HPPD inhibitors. Notably, the <em>Os</em>HSL2-M4 mutant exhibited enhanced metabolic activity for BBC-OH and methyl-benquitrione, while the <em>Os</em>HSL4-M5 mutant completely metabolized BBC-OH and topramezone. Additionally, the <em>Sb</em>HSL1-M4 mutant showed significant improvement in the metabolism of BBC-OH and several other herbicides, providing strong evidence to support the use of structure-guided HSL mutations to enhance crop resistance to HPPD inhibitors.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 1","pages":"Pages 41-48"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147454308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

TMK1 phosphorylates and stabilizes PIN2 to reinforce auxin flux during root gravitropism TMK1磷酸化和稳定PIN2，以加强根向地性过程中的生长素通量

Advanced Agrochem Pub Date : 2026-03-01 Epub Date: 2026-01-19 DOI: 10.1016/j.aac.2026.01.004

Yuanyuan Li, Pengyue Zhao

引用次数: 0

Carbonyl-bridged trifluoromethyl pyridine derivatives for pest control and mechanistic investigations 羰基桥接三氟甲基吡啶衍生物的害虫防治及其机理研究

Advanced Agrochem Pub Date : 2026-03-01 Epub Date: 2025-06-06 DOI: 10.1016/j.aac.2025.05.003

Zhubo Sheng , Jie Deng , Qinglong Yuan , Wen Fu , Zhiping Xu , Xiaoyan Li , Zhong Li , Xusheng Shao

引用次数: 0

The capability of synthetic cytokinin mimics for in vitro regeneration of plants 合成细胞分裂素模拟物对植物离体再生的影响

Advanced Agrochem Pub Date : 2026-03-01 Epub Date: 2025-09-16 DOI: 10.1016/j.aac.2025.09.002

Mahboobeh Mazinani , Mostafa K. Sarmast , Azim Ghasemnezhad , Liang Cheng

{"title":"The capability of synthetic cytokinin mimics for in vitro regeneration of plants","authors":"Mahboobeh Mazinani , Mostafa K. Sarmast , Azim Ghasemnezhad , Liang Cheng","doi":"10.1016/j.aac.2025.09.002","DOIUrl":"10.1016/j.aac.2025.09.002","url":null,"abstract":"<div><div>Among plant hormones, cytokinins have been extensively studied for over a century due to their central roles in regulating plant development, physiology, and environmental responses. In this study, we chemically synthesized several Cytokinin-Active ingreDients (CADs) and evaluated their effects on the <em>in vitro</em> regeneration of <em>Sansevieria trifasciata</em> and seedling growth of <em>Nicotiana tabacum</em>, comparing their activities with established cytokinins, kinetin and zeatin. Our results show that CADs promote cell division and shoot proliferation in <em>S. trifasciata</em>, with the highest shoot numbers per explant observed at CAD-A (0.9 mg L<sup>−1</sup>), cycle-iP (0.1 mg L<sup>−1</sup>), and zeatin (0.3 mg L<sup>−1</sup>), all significantly different from kinetin (0.3 mg L<sup>−1</sup>)—the previously suggested cytokinin for <em>in vitro</em> shoot proliferation in this plant. CAD-A and CAD-B at 0.9 mg L<sup>−1</sup> increased leaf number by approximately 4.5, significantly outperforming kinetin at 0.3 mg L<sup>−1</sup>. In tobacco seedlings, CAD-B at 0.3 mg L<sup>−1</sup> significantly enhanced root number (7.3) comparable to kinetin (6.7) at the same concentration. Overall seedling height increased more than two-fold under both CAD-B and kinetin treatments compared to control plants. The bioactivity of CADs under <em>in vitro</em> conditions closely parallels that of kinetin, supporting their potential as effective cytokinin mimetics. Collectively, these results indicate that synthesized CADs can serve as potent alternatives to natural cytokinins for plant tissue culture and developmental studies, with promising applications in propagation and regeneration protocols.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 1","pages":"Pages 65-71"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147454311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nature: Decoding 4-vinylanisole biosynthesis and pivotal enzymes in locusts Nature：解码蝗虫的4-乙烯基苯醚生物合成和关键酶

Advanced Agrochem Pub Date : 2026-03-01 Epub Date: 2025-11-11 DOI: 10.1016/j.aac.2025.11.001

Yueru Zhao, Zenglong Chen

引用次数: 0

SalicS1 FRET sensor enables real-time visualization of salicylic acid dynamics in plant immunity SalicS1 FRET传感器能够实时可视化水杨酸在植物免疫中的动态

Advanced Agrochem Pub Date : 2026-03-01 Epub Date: 2025-12-29 DOI: 10.1016/j.aac.2025.12.004

Shengmei Kang , Qiyuan Zhang , Feng Wang

引用次数: 0

Synthesis and insecticidal activity evaluation of sulfonamide derivatives oriented by atom replacement strategy 原子取代定向磺胺类衍生物的合成及杀虫活性评价

Advanced Agrochem Pub Date : 2026-03-01 Epub Date: 2025-06-10 DOI: 10.1016/j.aac.2025.06.001

Hao Qian , Xinru Tan , Guixun Wu , Lei Wang , Ziyu Wang , Hongxiang Liu , Mei Tian , Minjie Zhang , Keyin Yu , Wenjun Wu , Jiwen Zhang

{"title":"Synthesis and insecticidal activity evaluation of sulfonamide derivatives oriented by atom replacement strategy","authors":"Hao Qian , Xinru Tan , Guixun Wu , Lei Wang , Ziyu Wang , Hongxiang Liu , Mei Tian , Minjie Zhang , Keyin Yu , Wenjun Wu , Jiwen Zhang","doi":"10.1016/j.aac.2025.06.001","DOIUrl":"10.1016/j.aac.2025.06.001","url":null,"abstract":"<div><div>The single-atom replacement strategy is a typical approach which just converts elements in lead compounds into their analogues with very small chemical changes. In this research, we implemented this strategy to modify the sulfonamide scaffold identified in our previous work, and resulting in the synthesis of 40 novel sulfonamide derivatives not previously reported in the literature. The insecticidal activities of these compounds against the <em>Mythimna separata</em> and <em>Plutella xylostella</em> were assessed. Our findings indicate that the pyridine sulfonamide structure significantly enhances insecticidal efficacy. Specifically, compound <strong>7c</strong> exhibited LC<sub>50</sub> values of 0.157 and 0.256 mg/mL against the <em>M. separata</em> and <em>P. xylostella</em>, which significantly increased 97- and 41-fold compared to celangulin V, respectively. The experimental results revealed that pyridine sulfonamide analogues could serve as potential green insecticides.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 1","pages":"Pages 49-57"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147454309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0