Advanced Agrochem最新文献

{"title":"Light conversion film of biodegradable cellulose composite with fluorophores doped silica nanoparticles for plant growth","authors":"Zheng-En Piao,&nbsp;Xueli Shen,&nbsp;Jingzhou Guo,&nbsp;Xiaoxie Ma,&nbsp;Xinru Zhang,&nbsp;Yuan Pu,&nbsp;Jun Yin,&nbsp;Dan Wang","doi":"10.1016/j.aac.2026.03.002","DOIUrl":"10.1016/j.aac.2026.03.002","url":null,"abstract":"<div><div>Rational manipulation of solar spectrum represents a promising strategy to enhance crop productivity and agricultural light conversion films transforming non-utilized or low-efficiency solar photons into photosynthetically active radiation have attracted much attention in modern agriculture. Nevertheless, the poor dispersibility of conventional organic fluorophores in aqueous media severely limit their direct application in water-based polymer matrices. Herein, the 2-(4-bromophenyl)-3-(4-(4-(diphenylamino) styryl) phenyl) fumaronitrile (TPABDFN) with red luminescence was used as light conversion agent and nanocomposite films of biodegradable hydroxypropyl methylcellulose (HPMC) with TPABDFN doped silica nanoparticles (TPABDFN@SiO₂) were synthesized, exhibiting excellent colloidal stability and intense fluorescence in aqueous solution. Highly transparent light conversion films were fabricated by uniformly incorporating TPABDFN@SiO₂ nanoparticles into a HPMC matrix via a facile solution blending process with smooth surface morphology and favorable thermal stability. The film efficiently converted a portion of incident solar radiation into red light, thereby was expected to be used for improving photosynthetic efficiency and significantly promoting crop biomass accumulation. This study provides a versatile strategy for integrating hydrophobic fluorophores into hydrophilic polymer systems and offers a design paradigm for advanced spectral-modulation materials aimed at sustainable agricultural productivity.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 3","pages":"Pages 377-386"},"PeriodicalIF":9.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149007181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A solarization-triggered fungicide controlled-release platform enabled by “carrier-in-carrier” hiberarchy for on-demand soil-borne disease defense","authors":"Peng Peng,&nbsp;Meng Li,&nbsp;Haoran Zhao,&nbsp;Peng Ding,&nbsp;Ruizhi Shen,&nbsp;Jie Hu,&nbsp;Yang Guo,&nbsp;Hao Zhang,&nbsp;Youpeng Xiong,&nbsp;Li Cui,&nbsp;Xin Jia","doi":"10.1016/j.aac.2026.02.004","DOIUrl":"10.1016/j.aac.2026.02.004","url":null,"abstract":"<div><div>Soil application of fungicides is a primary control strategy for soil-borne diseases, while soil solarization provides an economical and eco-friendly supplementary approach. Herein, we propose a novel “carrier-in-carrier” photothermal-responsive delivery system (ANTs) to integrate soil solarization with on-demand fungicide release for sustainable management of soil-borne diseases. The fungicide azoxystrobin (AZOX) was first loaded into inner Cu-PDA nanobottles (Cu-PDA NBs), which were further embedded <em>in situ</em> within an outer lauric acid (LA)-EtOH-H₂O ternary eutectic phase-change matrix (TPS) via a solvent exchange-driven phase change strategy. The resulting ANTs exhibit superior photothermal-controlled release performance. Under solarization, the high photothermal conversion efficiency of Cu-PDA NBs rapidly triggers the solid-to-liquid phase transition of TPS (∼39 °C), enabling sequential AZOX release from TPS and Cu-PDA NBs. This design synchronizes fungicide release with solarization-enhanced soil disinfection while balancing initial burst release with long-term sustained delivery. In the absence of solarization, solidified TPS confines vertical AZOX migration, reducing soil leaching by 8% compared to commercial SC formulations, thereby maintaining effective fungicidal concentrations and mitigating groundwater contamination risks. Using <em>Verticillium dahlia</em> (strain V991) as a model pathogen, ANTs demonstrate a 30% lower median effective concentration (EC₅₀ = 0.900 mg/L) than commercial formulations, attributed to synergistic antifungal effects of LA and Cu-PDA NBs. In vivo cotton trials confirm 20% higher control efficacy of ANTs against <em>Verticillium wilt</em> under solarization than commercial formulations. The hierarchical carrier structure endows ANTs with minimal phytotoxicity to cotton germination, high biological safety to earthworms, and reduced impacts on dominant soil microorganisms. This work pioneers a solarization-compatible pesticide delivery platform bridging advanced material design with field-applicable disease control strategies.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 3","pages":"Pages 333-348"},"PeriodicalIF":9.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149007178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scaffold hopping in agricultural antibacterials: Research progress and prospects","authors":"Yong Zhang,&nbsp;Hehe Yang,&nbsp;Mingxing Li,&nbsp;Yuan Cao,&nbsp;Jingjing Zhang,&nbsp;Yuxiu Liu,&nbsp;Hongjian Song,&nbsp;Qingmin Wang","doi":"10.1016/j.aac.2026.04.005","DOIUrl":"10.1016/j.aac.2026.04.005","url":null,"abstract":"<div><div>Plant bacterial diseases cause substantial economic losses in agricultural production annually. Conventional agricultural antibacterial agents, including copper-based formulations and antibiotics, exhibit notable limitations, underscoring the urgency for developing novel agricultural antibacterial agents. Scaffold hopping is a viable strategy to address key challenges in antibacterial agent development (such as insufficient bioactivity, intellectual property barriers, high structural complexity of lead compounds, poor metabolic stability, and adverse toxicological profiles), thereby enabling the generation of isomeric functional molecules with comparable or enhanced properties. To facilitate the development of novel, high-efficiency, low-toxicity agricultural antibacterial agents, we systematically review the application of scaffold hopping in the development of antibacterial derivatives. Notably, scaffold hopping combined with structure-activity relationship (SAR) analyses can address the inherent limitations of developing novel antibacterials, expand the active molecule chemical space, and improve derivative development efficiency. We also summarized and prospectively discussed the application of scaffold hopping in antibacterial agent derivatives and their mechanisms. Scaffold hopping can offer valuable insights into the development of antibacterial derivatives and is of guiding significance for the research and development of novel antibacterial agrochemicals.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 3","pages":"Pages 231-250"},"PeriodicalIF":9.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149007189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilizing cationic liposome to co-deliver poly-siRNA and chlorantraniliprole complexes: A new strategy for overcoming insecticide resistance in Plutella xylostella (Lepidoptera: Plutellidae)","authors":"ZhiPing Xu ,&nbsp;XinQian Wang ,&nbsp;Xusheng Shao ,&nbsp;YangYang Yang ,&nbsp;Kun Yan Zhu","doi":"10.1016/j.aac.2025.08.001","DOIUrl":"10.1016/j.aac.2025.08.001","url":null,"abstract":"<div><div>The diamondback moth (<em>Plutella xylostella</em>) is a widely distributed pest recognized for its damaging effects on cruciferous crops and its rapid development of resistance to insecticides, particularly chlorantraniliprole (CAP). This study aims to develop new strategies for managing CAP resistance through the co-delivery of CAP and poly-siRNA targeting cytochrome P450 (CYP) genes. Utilizing a cationic liposome (CTL), we developed a unique co-delivery system for CTL-CAP/poly-siRNA-CYP complexes, characterized by an average particle size of 705 nm, a surface charge of +25 mV, and an impressive polydispersity index (PDI) of 0.12, demonstrating good formulation quality. Feeding bioassays revealed a remarkable capacity of these complexes to suppress CYP genes (<em>CYP6BG1</em> and <em>CYP6BF1v4</em>) expression in both the moderately CAP-resistant (CAP-SJ) and highly resistant (CAP-QP) <em>P. xylostella</em>, resulting in an about 30 % enhancement in CAP efficacy compared to the control group. This synergistic approach is among the first to combine RNAi and insecticides to combat resistance in this pest. This groundbreaking research not only introduces an innovative method for integrating RNAi-mediated gene silencing with chemical insecticides, but also significantly improves the effectiveness of CAP against resistant <em>P. xylostella</em> populations.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 2","pages":"Pages 108-119"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147896889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of biosafety pyrazole-5-sulfonamide derivatives for sustainable control of peanut stem rot","authors":"Xiang Cheng ,&nbsp;Fanglei Wang ,&nbsp;Shumeng Wang ,&nbsp;Yiyang Shao ,&nbsp;Yuting Hu ,&nbsp;Dandan Wang ,&nbsp;Guogen Yang ,&nbsp;Xianhai Lv ,&nbsp;Qiang Bian ,&nbsp;Xihao Chang","doi":"10.1016/j.aac.2025.08.002","DOIUrl":"10.1016/j.aac.2025.08.002","url":null,"abstract":"<div><div><em>Sclerotium rolfsii</em> threatens global peanut production with 15–80 % yield losses. Fungicide resistance to SDHIs (e.g., <strong>thifluzamide</strong>) and triazoles demands novel antifungal agents. Nineteen pyrazole-5-sulfonamide derivatives (<strong>E1 - E19</strong>) were synthesized and these antifungal activities were evaluated via <em>in vitro</em> EC₅₀, <em>in vivo</em> greenhouse assays, and mechanistic studies (scanning electron microscopy (SEM), transmission electron microscopy (TEM), reactive oxygen species (ROS), membrane integrity, and transcriptomics). These results showed that compound <strong>E10</strong> exhibited superior <em>in vitro</em> anti-<em>S. rolfsii</em> activity (EC₅₀ = 0.53 mg/L) rivaling <strong>thifluzamide</strong> (EC₅₀ = 0.58 mg/L), and <em>in vivo</em> trials demonstrated <strong>E10</strong> (200 mg/L) conferred 78.93 % protective and 75.65 % curative efficacy against peanut stem rot, comparable to <strong>thifluzamide</strong> (84.46 %/81.33 %). <strong>E10</strong> suppressed sclerotia production and germination, disrupted hyphal ultrastructure, and induced membrane damage via ROS burst. Transcriptomics revealed <strong>E10</strong>-triggered dysregulation of oxidative phosphorylation and fatty acid degradation pathways, linking ROS-mediated lipid peroxidation to fungal death. In addition, low phytotoxicity on peanut seedlings at 200 mg/L of <strong>E10</strong> with germination rates &gt;85 % and no morphological abnormalities, and <strong>E10</strong> showed low ecotoxicity (<em>Eisenia fetida</em> LC₅₀ &gt; 200 mg/kg). Compound <strong>E10</strong> demonstrated promise as a low ecological risk fungicide against <em>S. rolfsii</em> warranting further study.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 2","pages":"Pages 120-131"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147906166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanosensors convert H2O2 to machine-learnable thermal signatures in plants","authors":"Xinzan Liu,&nbsp;Ze Liang,&nbsp;Chenlu He,&nbsp;Haifeng Dai,&nbsp;Lili Wang","doi":"10.1016/j.aac.2025.10.003","DOIUrl":"10.1016/j.aac.2025.10.003","url":null,"abstract":"<div><div>Abiotic stresses including drought and salt can severely inhibit plant growth and represent major threats to agricultural productivity. Hydrogen peroxide (H₂O₂) serves as a key signaling mediator in plant stress response mechanisms, making the real-time monitoring of its spatiotemporal dynamics essential for research in plant phenology. This study presents an innovative detection approach that employs nanosensors to convert subtle endogenous H₂O₂ fluctuations at sub-micromolar concentrations into machine-readable infrared thermal signals. These thermal imaging data are processed via an advanced deep learning framework, enabling non-invasive in situ monitoring of H₂O₂ in plants under stress. Experimental results demonstrate that the average classification accuracy of multiple deep learning models reaches 98.8 ​% and 99.6 ​% on test sets under drought and salt stress conditions, respectively. Unlike conventional methods that focus primarily on data processing and model refinement, our method emphasizes the data source itself, significantly enhancing classification accuracy by capturing thermal data with distinctive features. The integration of interdisciplinary techniques offers a non-destructive, rapid, and accurate means for early detection of various plant stresses, thereby providing a new perspective for the study of plant stress characterization.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 2","pages":"Pages 145-154"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147910773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gibberellin biosynthesis inhibitors in wheat and rice: architectural regulation, agronomic trade-offs, and emerging opportunities","authors":"Deng-Ke Ma ,&nbsp;You Mo ,&nbsp;A-Li Dai ,&nbsp;Xiong Zhang ,&nbsp;Liu-Sheng Duan ,&nbsp;Meng-Jun Tan ,&nbsp;Wei-Ming Tan","doi":"10.1016/j.aac.2026.01.005","DOIUrl":"10.1016/j.aac.2026.01.005","url":null,"abstract":"<div><div>Gibberellins (GAs) are central regulators of plant architecture, and their targeted modulation has played a pivotal role in crop improvement. The introduction of semi-dwarf wheat and rice through mutations in GA metabolism and signaling underpinned the Green Revolution and reshaped global agriculture. Beyond genetic approaches, chemical inhibition of GA biosynthesis offers a reversible, stage-specific, and versatile means of fine-tuning growth. In cereals such as wheat (<em>Triticum aestivum</em>) and rice (<em>Oryza sativa</em>), gibberellin biosynthesis inhibitors (GBIs) have been widely employed to enhance lodging resistance, optimize canopy structure, and stabilize yield under high-density planting. Here, we synthesize advances in GA biosynthetic pathways and their chemical regulation, classify major GBIs by structure and mechanism, with emphasis on their roles in regulating growth and yield formation in wheat and rice. Despite demonstrated efficacy, several challenges restrict broader application, including environmental residues, weather-dose-response models, innovation and application, and integration with agronomic management measures. We also emphasized the design of next-generation GBIs, AI-assisted GBIs screening, and the establishment of dose models. By integrating these approaches, GBIs may become a cornerstone of sustainable cereal intensification. This review provides both mechanistic insights and practical guidance for advancing GBI-based regulation of plant architecture, offering new opportunities for yield stability and resource-efficient production in the face of global climate change.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 2","pages":"Pages 76-88"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148208487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PBAT/PPCP biodegradable mulching films with enhanced weatherability and water barrier properties for increased cotton yields","authors":"Xuan Wu ,&nbsp;Kun Zhang ,&nbsp;Jiayin Wang ,&nbsp;Ruihao Zhao ,&nbsp;Ruxia Ning ,&nbsp;Xiwang Shang ,&nbsp;Bing Zhang ,&nbsp;Yuanyuan Gao ,&nbsp;Mengtong Zhang ,&nbsp;Pengpeng Jiang ,&nbsp;Geoffrey I.N. Waterhouse ,&nbsp;Jiazhuo Xie ,&nbsp;Jing Xu","doi":"10.1016/j.aac.2025.10.004","DOIUrl":"10.1016/j.aac.2025.10.004","url":null,"abstract":"<div><div>Agricultural \"white pollution\" drives demand for fully biodegradable mulching films, among which poly (butylene adipate-co-terephthalate) (PBAT) films are especially attractive due to their excellent toughness and transparent properties. However, the insufficient weatherability and water barrier properties limit its practical applications. To overcome these issues, we combined biodegradable poly (propylene carbonate-co-phthalate) (PPCP) with PBAT via melt blending, followed by extrusion blow molding to fabricate PBAT/PPCP composite films. The composite films containing 30 ​wt% PPCP (denoted herein as PPCP-30) exhibited excellent weatherability, water barrier properties, and mechanical durability. The water vapor transmission rate of PPCP-30 films was reduced by 61.9 ​% compared to pure PBAT films. More notably, the PPCP-30 films retained 98.14 ​% of their initial nominal strain at break and 64.03 ​% of their initial tensile strength after indoor UV-accelerated aging tests, far outperforming pure PBAT films. Field trials in cotton cultivation in Xinjiang (China) confirmed that the PBAT/PPCP composite films exhibit superior durability and weatherability compared to conventional mulching films, directly boosting cotton productivity. This work highlights a practical and scalable approach to simultaneously improve weatherability, water barrier properties, and mechanical durability of biodegradable PBAT-based films, facilitating their application in sustainable agriculture and providing a promising solution to combat agricultural plastic pollution.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 2","pages":"Pages 155-167"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148208466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic evaluation of PLGA as a pesticide carrier: Impact on cucumber seedling growth and metabolic pathways","authors":"Yuanyuan Li,&nbsp;Lianxuan Zhou,&nbsp;Lidong Cao,&nbsp;Qiliang Huang,&nbsp;Pengyue Zhao","doi":"10.1016/j.aac.2025.11.003","DOIUrl":"10.1016/j.aac.2025.11.003","url":null,"abstract":"<div><div>Poly (lactic acid-glycolic acid) copolymer (PLGA) is recognized for its excellent mechanical properties and low toxicity, leading to its widespread use in the medical industry. Additionally, it shows potential applications in agriculture. While previous studies confirm PLGA's low toxicity in medicine, its role as a pesticide carrier may reduce negative impacts on plant growth. However, the safety of pesticide-loaded PLGA for plants remains uncertain. This study investigates its effects on cucumber seedling growth and metabolism. PLGA is synthesized using the emulsification method, and azoxystrobin (AZO) is loaded through solvent volatilization. Comparisons are made between PLGA, AZO, AZO-loaded PLGA (AZO@PLGA), and a blank control (CK). Transcriptome and metabolome analyses are conducted to evaluate treatment effects. The results indicate that PLGA generally has minimal impact on cucumber seedling growth. Although AZO@PLGA mitigates some negative effects linked to AZO, it is mainly the active ingredient AZO that significantly affects plant growth. The influence of AZO@PLGA should not be viewed as a simple additive effect; rather, it represents an innovative research target in itself. This study offers the first systematic evaluation of how PLGA pesticide carriers affect various metabolic pathways in cucumber seedlings, providing crucial insights for designing effective PLGA carriers.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 2","pages":"Pages 168-178"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148208467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction of star polycation-enabled delivery system for pymetrozine nanometerization: Enhanced aphid control and excellent ecological safety","authors":"Che Li ,&nbsp;Qinhong Jiang ,&nbsp;Yuansheng Huang ,&nbsp;Yitong Xu ,&nbsp;Zunlong Jiang ,&nbsp;Li Zhou ,&nbsp;Jie Shen ,&nbsp;Jiaying Li ,&nbsp;Shuo Yan","doi":"10.1016/j.aac.2025.12.003","DOIUrl":"10.1016/j.aac.2025.12.003","url":null,"abstract":"<div><div>The long-term irrational use of conventional chemical pesticides places considerable pressure on agroecosystems. As an emerging tool, nanotechnology shows great promise for enhancing pesticide activity and utilization efficiency. In this study, the star polycation (SPc) and pymetrozine (PYM) combine to form a novel nanopesticide (PYM@SPc) via hydrogen bond-driven self-assembly, whose physicochemical properties and bioactivity are systematically evaluated. The results show that PYM@SPc forms a rod-like nanoparticle (approximately 424 ​nm). The PYM@SPc significantly reduces the droplet contact angle, improves spreading and adhesion on both leaf surfaces and pest cuticles, and greatly enhances plant uptake (1.38-fold). Bioassays demonstrate that the PYM@SPc markedly enhances both stomach toxicity (26.67 ​%) and integrated toxicity (36.67 ​%) against green peach aphids (<em>Myzus persicae</em>), while field trials further confirm its superior control efficacy (91.19 ​%) compared with free PYM (61.19 ​%). Ecotoxicological assessment reveals that even at high concentrations, the formulation does not negatively affect the hatching or emergence rates of natural enemies (<em>Harmonia axyridis</em>, <em>Arma chinensis</em> and <em>Trichogramma ostriniae</em>). Taken together, this study presents a low-cost nano-delivery strategy that achieves high efficacy of PYM at low doses, while ensuring the ecological safety of non-target natural enemies.</div></div>","PeriodicalId":100027,"journal":{"name":"Advanced Agrochem","volume":"5 2","pages":"Pages 194-205"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147333492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}