Ali Manouchehrinia, Kathryn C Fitzgerald, Amber Salter, Ruth Ann Marrie, Lars Alfredsson, Charles N Bernstein, James M Bolton, Gary Cutter, John D Fisk, Lesley A Graff, Carol A Hitchon, Jan Hillert, Ingrid Kockum, Yi Lu, Fred D Lublin, Kyla McKay, Tomas Olsson, Scott Patten, Amit Patki, Hayley Riel, Klementy Shchetynsky, Pernilla Stridh, Hemant K Tiwari, Jerry S Wolinsky, Kaarina Kowalec
{"title":"Depression Polygenicity and Disease Activity and Disability Worsening in Multiple Sclerosis.","authors":"Ali Manouchehrinia, Kathryn C Fitzgerald, Amber Salter, Ruth Ann Marrie, Lars Alfredsson, Charles N Bernstein, James M Bolton, Gary Cutter, John D Fisk, Lesley A Graff, Carol A Hitchon, Jan Hillert, Ingrid Kockum, Yi Lu, Fred D Lublin, Kyla McKay, Tomas Olsson, Scott Patten, Amit Patki, Hayley Riel, Klementy Shchetynsky, Pernilla Stridh, Hemant K Tiwari, Jerry S Wolinsky, Kaarina Kowalec","doi":"10.1002/ana.70020","DOIUrl":"https://doi.org/10.1002/ana.70020","url":null,"abstract":"<p><strong>Objective: </strong>A better understanding of factors associated with multiple sclerosis (MS) disease activity and disability is needed. Given the strong link between comorbid depression and MS disease activity and disability, we aimed to determine whether the depression genetic burden, as modelled using its polygenic score, is associated with MS disease activity and disability worsening.</p><p><strong>Methods: </strong>In this cohort study, we used samples from neurologist-defined adult people with MS (PwMS) followed in clinical care or during a clinical trial from existing cohorts: Canada, the United States (US), and Sweden with extensive longitudinal phenotypes. We computed the depression polygenic score (PGS) and tested its association with annualized relapse rate and worsening disability. In the US cohort, we additionally explored the time to relapse, number of enhancing lesions, and confirmed Expanded Disability Status Scale (EDSS) worsening during the study period.</p><p><strong>Results: </strong>We included 3,420 relapsing-onset PwMS of European genetic ancestry with a median follow-up of 3 to 5 years. Meta-analyses revealed for each 1-standard deviation increase in the depression PGS, the relapse rate increased (incidence rate ratio: 1.23, 95% confidence interval [CI] = 1.01-1.50). In the US cohort, higher depression PGS was associated with protocol-defined relapses (hazard ratio [HR] = 1.58, 95% CI = 1.03-2.43), and time to confirmed EDSS worsening (HR = 1.51, 95% CI = 1.03-2.22) with this effect largely direct.</p><p><strong>Interpretation: </strong>Meta-analyses showed a higher depression genetic burden was associated with increased MS disease activity. In the US clinical trial cohort only, we found a significant association between higher depression PGS and time to relapse and confirmed EDSS worsening. These findings may provide insights into MS disease activity and disability worsening. ANN NEUROL 2025.</p>","PeriodicalId":127,"journal":{"name":"Annals of Neurology","volume":" ","pages":""},"PeriodicalIF":7.7,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katja Senf, Sandor Nietzsche, Martin Westermann, Eva M Neuhaus
{"title":"Unraveling the Role of Ensheathing Cells and Perineural Fibroblasts in Olfactory Neurogenesis.","authors":"Katja Senf, Sandor Nietzsche, Martin Westermann, Eva M Neuhaus","doi":"10.1002/glia.70076","DOIUrl":"https://doi.org/10.1002/glia.70076","url":null,"abstract":"<p><p>During development and following injury-induced neurogenesis, olfactory ensheathing cells (OECs) envelope the axon bundles of sensory neurons and support their growth to the glomerular destinations in the olfactory bulb. Transplantation of OECs to various neuronal injury locations showed a reparative impact; however, there was huge variability. By combining mRNA sequencing with bioinformatics analysis and immunohistochemistry, we characterized the cellular and molecular biological properties of OECs of the lamina propria and their response to neuronal injury. We found that OECs do not express NGFR (p75) under steady state conditions, questioning the common approach of isolating OECs with NGFR antibodies. While OECs express a peculiar combination of markers of different types of glial cells, they are strikingly similar to satellite glia cells of the dorsal root ganglion; for example, they showed marked upregulation of genes involved in lipid metabolism during neuronal regeneration. Similar to satellite glia cells and unlike Schwann cells, adult OECs did not proliferate in response to injury. Like endothelial cells at the blood-brain barrier and unlike other glia types, OECs showed extensive connections via the tight junction protein Claudin 5. Furthermore, OECs lack water channels, which probably explains why they sustain a stable environment after olfactory epithelium ablation. Regulation of the extracellular osmolarity seems to involve Aquaporin 1 in perineural fibroblasts together with high levels of KCNJ10, Na<sup>+</sup>K<sup>+</sup>ATPase, and gap junctions in OECs. Optimizing the clinical uses of these unique glia cells is probably made easier by this thorough characterization of marker gene expression in steady state and during neurogenesis.</p>","PeriodicalId":174,"journal":{"name":"Glia","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AddictionPub Date : 2025-08-07DOI: 10.1111/add.70159
Sarah E Jackson, Jamie Brown, Lion Shahab, Sharon Cox
{"title":"Associations between non-daily smoking and motivation to stop smoking: A population study in England 2021-2024.","authors":"Sarah E Jackson, Jamie Brown, Lion Shahab, Sharon Cox","doi":"10.1111/add.70159","DOIUrl":"https://doi.org/10.1111/add.70159","url":null,"abstract":"<p><strong>Background and aims: </strong>An increasing proportion of adults in England who smoke cigarettes do not smoke every day and may see quitting smoking as less important than those who smoke daily. This study aimed to examine whether motivation to stop smoking differs between those who smoke cigarettes daily vs. non-daily, and to explore differences in this association by relevant sociodemographic, smoking and vaping-related factors.</p><p><strong>Design and setting: </strong>Observational study using data drawn from the Smoking Toolkit Study, a representative cross-sectional survey in England, 2021-2024.</p><p><strong>Participants: </strong>13 277 cigarette smokers (≥16 y).</p><p><strong>Measures: </strong>Outcome variables were level of motivation to stop smoking (Motivation to Stop Scale), analysed as a 7-level ordinal variable and dichotomised to assess (1) no desire to stop smoking and (2) high motivation to stop smoking. The exposure variable was daily vs. non-daily smoking. Covariates and potential moderators were age, gender, socioeconomic position, presence of children in the household, strength of urges to smoke, vaping status, harm perceptions of e-cigarettes vs. cigarettes and survey year.</p><p><strong>Results: </strong>Non-daily (vs. daily) smoking was associated with greater motivation to stop smoking [adjusted odds ratio (OR<sub>adj</sub>) = 1.22 (95% confidence interval, CI = 1.13-1.32)]. Non-daily smokers were both less likely than daily smokers to report no desire to stop smoking [40.4% vs. 44.0%; OR<sub>adj</sub> = 0.85 (95% CI = 0.77-0.95)] and more likely to report high motivation to stop smoking [21.0% vs. 14.8%; OR<sub>adj</sub> = 1.78 (95% CI = 1.55-2.03)]. These differences in motivation-especially in the odds of reporting no desire to stop smoking-between non-daily and daily smokers were more pronounced among those who were older and less advantaged. Differences were less pronounced among those who reported no urges to smoke, those who vaped and those who perceived e-cigarettes to be less harmful than cigarettes.</p><p><strong>Conclusions: </strong>In England, adults who smoke cigarettes non-daily appear to tend to be more motivated to quit smoking than those who smoke every day, especially among older and less advantaged people.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sustained Metal Ion Release-Controlled Synthesis of Polyoxometalate Subnanowires.","authors":"Rongzhu Ma, Wenxiong Shi, Yifan Qin, Shange Qi, Simin Zhang","doi":"10.1002/smtd.202500825","DOIUrl":"https://doi.org/10.1002/smtd.202500825","url":null,"abstract":"<p><p>Subnanowires (SNWs) are similar to polymers in dimension, exhibiting distinctive polymer-like properties. They show not only multifunction due to the various inorganic compositions, but also good processability, which may become a bridge between conventional inorganic materials and polymers. Facile, strict, conditions-free, and scalable synthesis methods of SNWs are foundations of developing functional SNWs materials and devices. In this study, we develop a universal method for synthesizing SNWs composed of metal ions and phosphomolybdic acid nanoclusters (termed M-PMA SNWs) through a sustained-release strategy of metal ions, and successfully fabricate a series of these architectures. All of M-PMA SNWs can be processed into freestanding fibers and fabrics through electrospinning without polymer additives. Among them, the Ag-PMA SNW fabrics display good photothermal performance, which can be integrated into photothermal wearable fabrics. This work provides a highly practical synthesis method of M-PMA SNWs and combines functionalities and processability of SNWs effectively.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e00825"},"PeriodicalIF":9.1,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to editor in response to \"Clinical features of overt versus diagnosed pre-existing diabetes in pregnancy\".","authors":"Adnan Memon, Zareen Gull","doi":"10.1111/jdi.70136","DOIUrl":"https://doi.org/10.1111/jdi.70136","url":null,"abstract":"","PeriodicalId":190,"journal":{"name":"Journal of Diabetes Investigation","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Small MethodsPub Date : 2025-08-07DOI: 10.1002/smtd.202500740
Thomas Dursap, Tao Zhou, Maxime Dupraz, Stéphane Labat, Olivier Thomas, Niels Fardeau, Philippe Regreny, Michel Gendry, Solène Brottet, Nicholas P Blanchard, Martin V Holt, Marie-Ingrid Richard, Alexandru Danescu, José Penuelas, Matthieu Bugnet
{"title":"Correlated X-Ray and Electron Microscopies of a Single Biphasic GaAs Nanowire.","authors":"Thomas Dursap, Tao Zhou, Maxime Dupraz, Stéphane Labat, Olivier Thomas, Niels Fardeau, Philippe Regreny, Michel Gendry, Solène Brottet, Nicholas P Blanchard, Martin V Holt, Marie-Ingrid Richard, Alexandru Danescu, José Penuelas, Matthieu Bugnet","doi":"10.1002/smtd.202500740","DOIUrl":"https://doi.org/10.1002/smtd.202500740","url":null,"abstract":"<p><p>Engineering the properties of semiconductors by changing their crystalline phase is a technologically and economically relevant alternative to doping using foreign elements, with strong potential for photonic and electronic applications. Although major advances have been reported recently for crystal-phase engineering of III-V and group IV semiconductor nanowires, interfacing two mismatched crystalline phases in a nanostructure induces several deformation mechanisms, which remain largely unexplored. Here, using state-of-the-art synchrotron X-ray nanobeam diffraction and transmission electron microscopy, subtle twisting and bending is unveiled within an individual GaAs nanowire containing cubic and hexagonal segments. Their role is discussed in accommodating the inter-reticular spacing fluctuations, and their variations are correlated to the nanoscale phase distribution and to the effect of the NW support. This study brings direct evidence of a complex combination of deformation mechanisms in biphasic nanowires, which opens a new path to tune the nanowire properties with appealing perspectives for device engineering in nanophotonics and nanomechanics.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e2500740"},"PeriodicalIF":9.1,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toward ED Based Cardio Oncology Pathways From a Nationwide Arrhythmia Cohort","authors":"Yalcin Golcuk","doi":"10.1002/joa3.70167","DOIUrl":"https://doi.org/10.1002/joa3.70167","url":null,"abstract":"<p>The landmark study by Kobayashi and Kusano [<span>1</span>] provides invaluable insights into arrhythmia patterns among cancer patients using Japan's nationwide JROAD-DPC database. Despite the rising incidence of cardiovascular complications in oncology patients, few large-scale studies have examined arrhythmia profiles across cancer subtypes and treatment trajectories in real-world emergency settings. As emergency physicians (EPs) managing acute cardio-oncologic complications, we commend this study and wish to highlight three findings with critical implications for emergency care, along with opportunities to strengthen clinical translation.</p><p>The significantly higher rate of emergency admissions among cancer patients with arrhythmias (58.9% vs. 57.6% in non-cancer patients; <i>p</i> < 0.05) underscores a growing challenge for emergency departments (EDs). This finding aligns with global trends showing increasing cardiovascular emergencies related to malignancy due to aging populations and the widespread use of cardiotoxic therapies [<span>2</span>]. However, the underlying factors contributing to these admissions—whether related to arrhythmia severity, cancer progression, or gaps in outpatient care—remain insufficiently explored. Clarifying these drivers could enable the implementation of targeted interventions such as rapid-access cardio-oncology clinics or ED-based clinical triggers, including recurrent arrhythmia or recent chemotherapy exposure, for early cardiology consultation.</p><p>The predominance of atrial fibrillation or flutter (AF/AFL) among cancer-associated arrhythmias, comprising 70.6% of cases, has direct implications for acute management in the ED [<span>3</span>]. While the authors report lower anticoagulant use among cancer patients, EPs frequently face complex therapeutic dilemmas. Rhythm control may be constrained by QT-prolonging chemotherapies, and anticoagulation decisions must be cautiously balanced against risks of bleeding, especially in the context of thrombocytopenia or mucosal tumors. ED-specific algorithms would benefit from integrating oncology-informed variables such as current drug profiles, platelet counts, and malignancy characteristics to individualize AF management.</p><p>The observed frequencies of pneumonia (7.41%) and sepsis (2.26%) as clinical triggers for arrhythmia underscore the role of systemic inflammation in acute cardiac dysrhythmias. In the ED, febrile presentations in oncology patients often signal infection-related arrhythmogenic potential [<span>4</span>]. Embedding arrhythmia screening protocols, such as mandatory electrocardiograms for patients with febrile neutropenia, within sepsis bundles may support early detection of tachyarrhythmias and timely antimicrobial or hemodynamic intervention.</p><p>This study's use of nationwide claims data effectively captures broad epidemiologic trends; although coding limitations restrict the granularity of arrhythmia etiology and disease trajecto","PeriodicalId":15174,"journal":{"name":"Journal of Arrhythmia","volume":"41 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/joa3.70167","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144782277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yan Wang, Ling Luo, Peilin Huang, Shaofan Jiang, Xiaodong Pan
{"title":"Effects of Obstructive Sleep Apnea on Cognition: An Analysis of Electroencephalography Microstates and Alpha Peak Frequency","authors":"Yan Wang, Ling Luo, Peilin Huang, Shaofan Jiang, Xiaodong Pan","doi":"10.1111/cns.70553","DOIUrl":"https://doi.org/10.1111/cns.70553","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Respiration-related sleep disorders such as obstructive sleep apnea (OSA) are risk factors for mild cognitive impairment and age-related neurocognitive deficits. Nearly 60% of patients with OSA suffer from a variety of impaired cognitive functions, including attention, working memory, and episodic memory, and are susceptible to mood disorders such as depression and anxiety. However, it remains largely unexplored regarding the features of the electroencephalography (EEG) microstates of these patients and the potential association between the EEG microstates and the cognitive impairments.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>In this study, we performed polysomnography (PSG) on 70 patients who were recruited from the Department of Neurology and subsequently categorized into the OSA group (44 patients) and the non-OSA group (26 patients). We collected and analyzed their demographic information, blood and body fluid specimens, EEG alpha peak frequency, and EEG microstates.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Result</h3>\u0000 \u0000 <p>Compared with the non-OSA group, the OSA group reported more cases of comorbid anxiety symptoms (58.5% vs. 29%), and scored significantly lower in the word classification test. Of note, compared with the non-OSA counterparts, the OSA patients displayed markedly more microstate A, a significantly higher rate of B to A microstate conversion, and drastically lower Delta and Theta power at the F7-AV position.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>These findings confirm that OSA may affect sleep quality and cognitive function by influencing EEG activity and microstates, which highlights a potential EEG network mechanism for OSA-induced cognitive impairment.</p>\u0000 </section>\u0000 </div>","PeriodicalId":154,"journal":{"name":"CNS Neuroscience & Therapeutics","volume":"31 8","pages":""},"PeriodicalIF":5.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cns.70553","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144782297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GeobiologyPub Date : 2025-08-06DOI: 10.1111/gbi.70028
Jean N. R. Clemente, Haifeng Fan, Chadlin M. Ostrander, Hongjie Zhang, Hanjie Wen, Erik A. Sperling, Sune G. Nielsen
{"title":"Thallium Isotopes Suggest the Global Deep Ocean Did Not Approach Modern Oxygenation During Cambrian Age 3 Metazoan Radiation","authors":"Jean N. R. Clemente, Haifeng Fan, Chadlin M. Ostrander, Hongjie Zhang, Hanjie Wen, Erik A. Sperling, Sune G. Nielsen","doi":"10.1111/gbi.70028","DOIUrl":"https://doi.org/10.1111/gbi.70028","url":null,"abstract":"<div>\u0000 \u0000 <p>The geologically rapid appearance of most extant animal groups in the Cambrian fossil record is often linked to enhanced ocean oxygenation. However, conflicting reconstructions of the Cambrian redox landscape make it difficult to determine the extent of ocean oxygenation during this significant biotic event, particularly regarding the redox state of the global deep ocean. In this study, we present authigenic thallium isotope compositions (ε<sup>205</sup>Tl<sub>auth</sub>) for two shale sequences from South China (Qingjiang and Weng'an) that span the Cambrian Stage 2–3 boundary to the appearance of the Qingjiang biota, approximately 521–518 million years ago (Ma), a timeframe that chronicles a particularly rapid interval of metazoan diversification and radiation in the broader Cambrian explosion. If this event occurred amid modern-like extents of global ocean oxygenation, we would expect a significant increase in the global extent of seafloor Mn-oxide burial to drive lower ε<sup>205</sup>Tl<sub>auth</sub> values near the modern open-ocean composition of −6‱. Instead, we observe broadly stable ε<sup>205</sup>Tl<sub>auth</sub> values of around −3 to −4‱ in both studied sections. The lack of any significant Tl isotope shifts in our dataset argues against a short-term global ocean oxygenation event and suggests the global deep ocean was not characterized by modern extents of oxygenation 521–518 Ma. We reinterpret contemporaneous near-modern Mo and U isotope compositions to signal a relatively minor increase in marine oxygenation, likely limited to the continental shelves. However, ε<sup>205</sup>Tl<sub>auth</sub> lower than the average isotopic composition of approximately −2‱ in Ediacaran shales suggests a shift to comparatively better-oxygenated conditions sometime between ~555 Ma and 521 Ma. If diversification at this time was linked to increased ocean oxygen levels, these changes were likely more dominant in the relatively shallow-water settings of continental shelves most densely populated by Cambrian animals and were incapable of dramatically altering seawater Tl isotope mass balance through seafloor Mn-oxide burial.</p>\u0000 </div>","PeriodicalId":173,"journal":{"name":"Geobiology","volume":"23 4","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144782308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Junxuan Luo, Fujie Wang, Shaoxiang Shi, Fang Guo, Yi Qin, Zhongye Xie, Ming Jiang
{"title":"Event-Triggered Based Adaptive Improved Terminal Sliding Mode Control of Multi-Manipulators System With Weak Communication Networks","authors":"Junxuan Luo, Fujie Wang, Shaoxiang Shi, Fang Guo, Yi Qin, Zhongye Xie, Ming Jiang","doi":"10.1049/cth2.70055","DOIUrl":"https://doi.org/10.1049/cth2.70055","url":null,"abstract":"<p>In this paper, an event-triggered adaptive improved terminal sliding mode controller is proposed for addressing the consensus tracking problem of multi-manipulators system under the weak communication networks. Firstly, an improved terminal sliding surface is designed to reduce the steady-state error of system. Then, by devising a variable-rate reaching law for sliding surface, the control chattering is greatly weakened. Furthermore, a trigger mechanism with time-varying threshold is incorporated into the designed controller to adjust the update frequency of the control law for conserving communication resources. This strikes a balance between tracking accuracy and resources conservation. Eventually, the tracking performance of the weak-connected system is greatly improved under the proposed algorithm. Based on Lyapunov stability theory, it is proven that the consensus tracking error of the system asymptotically converges to zero. Simulation results verify the effectiveness and performance improvement of the proposed scheme.</p>","PeriodicalId":50382,"journal":{"name":"IET Control Theory and Applications","volume":"19 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/cth2.70055","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144782541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}