Wiley最新文献

{"title":"The thylakoid protein BCM1 sequesters antennae protein CP24 and CP29 within the grana cores thereby reducing their exposure to degradation under heat stress","authors":"Qiuxin Li,&nbsp;Wenjing An,&nbsp;Jinfang Ma,&nbsp;Hongmei Zhang,&nbsp;Manfei Luo,&nbsp;Yafei Qi,&nbsp;Jörg Meurer,&nbsp;Daili Ji,&nbsp;Wei Chi","doi":"10.1111/tpj.70060","DOIUrl":"https://doi.org/10.1111/tpj.70060","url":null,"abstract":"<div>\u0000 \u0000 <p>Photosystem II (PSII) is one of the most thermosensitive components of photosynthetic apparatus in higher plants. Heat-inactivation of PSII may be followed by dissociation of antenna proteins, however, the fate and regulation mechanism of detached antenna proteins during this process remains unclear. Here, we investigate the regulation mechanism of two minor antenna proteins CP24 and CP29 during heat acclimation via the study on a thylakoid protein BCM1. BCM1 is distributed in both grana cores (GC) and stroma lamellae of thylakoids. However, heat stress induced its accumulation in grana cores but not stroma lamellae. Deficiency of BCM1 leads to the decline of plant resilience to heat stress, which results from the accelerated degradation of CP24 and CP29 <i>in vivo</i>. Heat stress induces a redistribution of CP24 and CP29 from the grana cores to the stroma lamellae, a shift that is exacerbated in <i>bcm1</i> mutants, suggesting that migration of detached antennae proteins between thylakoid subcompartments may contribute to their degradation during heat acclimation. As an integral thylakoid protein, BCM1 physically interacts with CP24 and CP29. We propose that BCM1 serves as a stabilizing “anchor”, effectively sequestering CP24 and CP29 within the grana cores thereby reducing their exposure to degradation in the stroma lamellae.</p>\u0000 </div>","PeriodicalId":233,"journal":{"name":"The Plant Journal","volume":"121 5","pages":""},"PeriodicalIF":6.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Front Cover: Porous Organic Polymers for CO2 Capture and Catalytic Conversion (Chem. Eur. J. 13/2025)","authors":"Zicheng Zhong,&nbsp;Prof. Xiaoyan Wang,&nbsp;Prof. Bien Tan","doi":"10.1002/chem.202581301","DOIUrl":"https://doi.org/10.1002/chem.202581301","url":null,"abstract":"<p><b>Porous organic polymers</b> have garnered significant attention in carbon dioxide capture and catalytic conversion applications due to their high specific surface area, stable chemical properties, and ease of functionalization. The type of adsorption plays a crucial role in determining the adsorption efficiency and catalytic performance of these materials in CO₂ capture and conversion. The Review by Z. Zhong, X. Wang and B. Tan (DOI: 10.1002/chem.202404089) offers a brief comparison of the effects of different adsorption types on adsorption efficiency, as well as their influence on both chemo- and photocatalytic conversions. Additionally, a perspective on the future development of this field is provided.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":"31 13","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/chem.202581301","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complex and Dynamic Effects of an Extreme Low Temperature Weather Event on Invasive Plant Populations and Resident Communities","authors":"Maurício Cruz Mantoani,&nbsp;Conor Sweeney,&nbsp;Bruce A. Osborne","doi":"10.1111/gcb.70113","DOIUrl":"https://doi.org/10.1111/gcb.70113","url":null,"abstract":"<p>Whilst it is often assumed that invasive plant species may benefit more from climate change than native species, there is little empirical data on how they, and the communities they invade, respond to extreme weather events (EWEs). Here, we show that the effects of a low temperature EWE can result in a dramatic reduction in both vegetative and reproductive growth of invasive populations of <i>Gunnera tinctoria</i>, although a significant recovery was found within 1 year after its occurrence. Whilst the EWE decreased both the leaf/petiole numbers of mature plants, the major impact was on leaf expansion and a decrease in the size/number of inflorescences. Concomitant with the reduction in growth of <i>G. tinctoria</i>, there was a 5-fold increase in the number of resident species emerging in invaded areas, which largely persisted after the recovery of the invasive populations. Although the growth of <i>G. tinctoria</i> seedlings was also reduced, this was relatively small, and growth and development resumed almost immediately after the EWE. In comparison, the resident plant community was largely unaffected by the EWE either due to the later initiation of growth and/or because of their greater resilience to episodic low temperature events. Our results show that an EWE of this magnitude can have complex time-dependent effects on plant invasions and invaded communities, with a greater impact on the established invasive plants compared to newly recruited seedlings. Based on an assessment of historical climatic data, these long-lived populations have been exposed to EWEs of a similar or greater magnitude in the past, which have not constrained their spread or compromised recruitment. Given the likelihood of an almost complete absence of low temperature EWEs of similar magnitude in the future, any temporary restrictions on the growth of invasive <i>G. tinctoria</i> and other similar invasive species populations are likely to be small.</p>","PeriodicalId":175,"journal":{"name":"Global Change Biology","volume":"31 3","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/gcb.70113","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Injectable Glucose-Releasing Microgels Enhance the Survival and Therapeutic Potential of Transplanted MSCs Under Ischemic Conditions (Adv. Healthcare Mater. 6/2025)","authors":"Chieh-Cheng Huang,&nbsp;Chun-Kai Chang,&nbsp;Pei-Ching Yang,&nbsp;Han Chiu,&nbsp;Shih-Heng Chen,&nbsp;Li-Wen Hsu","doi":"10.1002/adhm.202570038","DOIUrl":"https://doi.org/10.1002/adhm.202570038","url":null,"abstract":"<p><b>Glucose-Releasing Microgels</b></p><p>In article 2401724, Chieh-Cheng Huang and co-workers present a glucose delivery system utilizing starch and amyloglucosidase within microgels. This system enables sustained glucose release, supporting the survival and enhancing the therapeutic potential of mesenchymal stem cells (MSCs) in ischemic milieus, offering significant promise for advancing MSC-based therapies for ischemic diseases.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":113,"journal":{"name":"Advanced Healthcare Materials","volume":"14 6","pages":""},"PeriodicalIF":10.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adhm.202570038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular Mechanisms of ARD1 in Tumors","authors":"Chunjiao Yu,&nbsp;Hongtao Lei,&nbsp;Xuefei Hou,&nbsp;Shan Yan","doi":"10.1002/cam4.70708","DOIUrl":"https://doi.org/10.1002/cam4.70708","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Arrest-deficient protein 1 (ARD1) is an acetyltransferase that acetylates the N-terminal amino acids and internal lysine residues of proteins. It plays a crucial role in various cellular processes. The significance of ARD1 in tumor development has become increasingly evident in recent years.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This review analyzes the regulatory role of ARD1 in tumor progression by examining its involvement in processes such as cell cycle regulation, cell proliferation, metastasis, apoptosis, and autophagy. Additionally, we discuss the expression patterns and molecular mechanisms of ARD1 in different types of cancer.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Elevated levels of ARD1 have been reported in several cancer types. Its increased expression is associated with various tumor characteristics, suggesting it may serve as a potential prognostic biomarker. Furthermore, ARD1 could be targeted for the development of novel cancer therapies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Understanding the role of ARD1 in tumor biology provides valuable insights into potential therapeutic targets and biomarkers for cancer treatment. This review highlights the advances in ARD1-related research and suggests that it may be a promising avenue for improving cancer prognosis and treatment strategies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":139,"journal":{"name":"Cancer Medicine","volume":"14 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cam4.70708","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cover Feature: Progress on Photo-, Electro-, and Photoelectro-Catalytic Conversion of Recalcitrant Polyethylene, Polypropylene, and Polystyrene - A Review (ChemSusChem 5/2025)","authors":"Bhanupriya Boruah,&nbsp;Juan A. Lopez-Ruiz","doi":"10.1002/cssc.202580503","DOIUrl":"https://doi.org/10.1002/cssc.202580503","url":null,"abstract":"<p><b>The Cover Feature</b> shows the fundamental forces of nature being harnessed to transform matter. Using catalysts to channel solar and electrical energy, we can convert pollutants into reusable molecules, thereby enabling a circular and carbon-neutral economy. The Review by B. Boruah and J. A. Lopez-Ruiz (DOI: 10.1002/cssc.202401714) focuses on how photo-, electro-, and photo-electrocatalytic processes degrade waste plastics into useful compounds. They also outline future research directions to advance this field.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":149,"journal":{"name":"ChemSusChem","volume":"18 5","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cssc.202580503","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Age on Preferences for Colorectal Cancer Surveillance Strategies: Are Fecal Immunochemical Tests FIT for Surveillance?","authors":"Maddison Dix,&nbsp;Sarah Cohen-Woods,&nbsp;Molla M. Wassie,&nbsp;Jean M. Winter,&nbsp;Carlene J. Wilson,&nbsp;Graeme P. Young,&nbsp;Charles Cock,&nbsp;Erin L. Symonds","doi":"10.1002/cam4.70723","DOIUrl":"https://doi.org/10.1002/cam4.70723","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Individuals with a known risk of colorectal cancer (CRC) are recommended regular surveillance colonoscopies. Alternative surveillance strategies incorporating fecal immunochemical tests (FIT) may improve colonoscopy resource utilization and be more appropriate for those with a lower risk of CRC, particularly younger adults. This study compared younger (&lt; 50 years) and older (≥ 50 years) adults' preferences for different CRC surveillance strategies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Eight hundred individuals enrolled in a colonoscopy-based surveillance program were invited to complete a survey assessing CRC surveillance preferences. Preferences for colonoscopy frequency and the acceptability of two alternative protocols were assessed: (1) providing FIT between colonoscopies, and (2) a FIT-only strategy where colonoscopy would only be required after a positive FIT result.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 102 younger (median age 41.4 years, 67.6% female) and 187 older (median age 68.5 years, 49.2% female) adults completed the survey. Surveillance preferences did not significantly vary by age group; most respondents preferred colonoscopies more often than their current frequency (&lt; 50 years: 54.1%; ≥ 50 years: 58.1%). Although most participants (&lt; 50 years: 91.2%; ≥ 50 years: 93.0%) agreed that FIT is important to complete between surveillance colonoscopies, only a small proportion were comfortable with FIT-only surveillance replacing colonoscopies (&lt; 50 years: 27.5%; ≥ 50 years: 37.4%). Fear of CRC was a significant predictor of preferences for more frequent surveillance incorporating FIT in younger, but not older, adults.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Many individuals with an elevated risk of CRC wanted more frequent surveillance, regardless of their age. Extending surveillance colonoscopy intervals using FIT may be a more acceptable method of reducing colonoscopy frequency rather than utilizing a FIT-only approach.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>This study was prospectively registered with the Australian New Zealand Clinical Trials Registry (ACTRN #12619001743156)</p>\u0000 </section>\u0000 </div>","PeriodicalId":139,"journal":{"name":"Cancer Medicine","volume":"14 5","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cam4.70723","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimating Spatially Explicit Survival and Mortality Risk From Telemetry Data With Thinned Point Process Models","authors":"Joseph M. Eisaguirre,&nbsp;Madeleine G. Lohman,&nbsp;Graham G. Frye,&nbsp;Heather E. Johnson,&nbsp;Thomas V. Riecke,&nbsp;Perry J. Williams","doi":"10.1111/ele.70092","DOIUrl":"https://doi.org/10.1111/ele.70092","url":null,"abstract":"<div>\u0000 \u0000 <p>Mortality risk for animals often varies spatially and can be linked to how animals use landscapes. While numerous studies collect telemetry data on animals, the focus is typically on the period when animals are alive, even though there is important information that could be gleaned about mortality risk. We introduce a thinned spatial point process (SPP) modelling framework that couples relative abundance and space use with a mortality process to formally treat the occurrence of mortality events across the landscape as a spatial process. We show how this model can be embedded in a hierarchical statistical framework and fit to telemetry data to make inferences about how spatial covariates drive both space use and mortality risk. We apply the method to two data sets to study the effects of roads and habitat on spatially explicit mortality risk: (1) VHF telemetry data collected for willow ptarmigan in Alaska, and (2) hourly GPS telemetry data collected for black bears in Colorado. These case studies demonstrate the applicability of this method for different species and data types, making it broadly useful in enabling inferences about the mechanisms influencing animal survival and spatial population processes while formally treating survival as a spatial process, especially as the development and implementation of joint analyses continue to progress.</p>\u0000 </div>","PeriodicalId":161,"journal":{"name":"Ecology Letters","volume":"28 3","pages":""},"PeriodicalIF":7.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to “Comment on Prevalence and Influencing Factors of Malnutrition in Diabetic Patients: A Systematic Review and Meta-Analysis”","authors":"Tong Zhang,&nbsp;Yuxia Ma,&nbsp;Lin Han","doi":"10.1111/1753-0407.70066","DOIUrl":"https://doi.org/10.1111/1753-0407.70066","url":null,"abstract":"&lt;p&gt;We thank the authors for their insightful comments and for recognizing that our manuscript provides valuable contributions to the field of clinical nutrition [&lt;span&gt;1&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Firstly, we acknowledge that meta-regression can provide additional insights into heterogeneity, but its feasibility and reliability in our study were constrained by the inconsistent and limited reporting of key covariates, such as sample characteristics, across the included studies, and current meta-analysis studies on single-group rates are all highly heterogeneous [&lt;span&gt;2, 3&lt;/span&gt;]. Additionally, even meta-regression analysis cannot completely resolve heterogeneity, which is inherent to meta-analysis investigating prevalence rates. Heterogeneity is now widely recognized and accepted as a standard challenge in such studies and is one of the issues to be addressed by future methodologists [&lt;span&gt;4&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Secondly, using Egger's test and funnel plots to assess publication bias are widely adopted methods, and while tools such as Doi plots and the LFK index may provide alternative methods for detecting publication bias, these methods have not been universally used in meta-analyses. We acknowledge that prediction intervals (PIs) can convey the range of effects expected in future studies, but calculating and interpreting PIs relies on normality assumptions, which may be difficult to guarantee. Importantly, retaining our original analysis methods does not alter the conclusions of this paper, which is why we opted to maintain them.&lt;/p&gt;&lt;p&gt;Thirdly, regarding malnutrition assessment tools, we note that a meta-analysis of 83 studies identified more than 30 nutritional assessment tools, none of which are universally applicable or specifically developed for diabetic patients [&lt;span&gt;5&lt;/span&gt;]. We recognize that pooling results from diverse tools introduces significant heterogeneity, but limiting analysis to stratified results would constrain the exploration of factors influencing malnutrition in diabetic patients. To address this, we performed subgroup analysis based on assessment tools. Furthermore, we also advocate for the development of a standardized malnutrition assessment tool tailored for diabetic patients to enhance consistency and comparability across studies.&lt;/p&gt;&lt;p&gt;Finally, we agree that the analysis of some influencing factors, such as smoking, education level, and diabetic foot infection, was limited by small sample sizes. Future studies should focus more on the impact of these factors on the nutritional status of diabetic patients. Additionally, future analysis should aim to incorporate confounding variables, including socioeconomic status, dietary patterns, and psychological factors, to provide a more comprehensive understanding of malnutrition risk.&lt;/p&gt;&lt;p&gt;In conclusion, we thank the authors for their comments on the manuscript and for providing valuable insights. We hope these clarifications address the issues raised and further illuminate our analytica","PeriodicalId":189,"journal":{"name":"Journal of Diabetes","volume":"17 3","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1753-0407.70066","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cellular Alignment and Matrix Stiffening Induced Changes in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes (Adv. Healthcare Mater. 6/2025)","authors":"Andrew House,&nbsp;Anjeli Santillan,&nbsp;Evan Correa,&nbsp;Victoria Youssef,&nbsp;Murat Guvendiren","doi":"10.1002/adhm.202570035","DOIUrl":"https://doi.org/10.1002/adhm.202570035","url":null,"abstract":"<p><b>Cardiac Tissue Engineering</b></p><p>A novel biomaterial platform enables user-controlled tuning of cellular alignment and matrix stiffness. This dynamic system reveals how human induced pluripotent stem cell-derived cardiomyocytes respond to changes in stiffness, illuminating cellular-microenvironment interactions and advancing cardiac tissue engineering. More details can be found in article 2402228, by Murat Guvendiren and co-workers.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":113,"journal":{"name":"Advanced Healthcare Materials","volume":"14 6","pages":""},"PeriodicalIF":10.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adhm.202570035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}