Wiley最新文献

{"title":"Methyl Jasmonate Seed Priming Mitigates the Defence-Growth Trade-Off and Tailors Plant Response to Specific Pests.","authors":"Lucia Talavera-Mateo, Adrian Sabater-Gabriel, Alejandro Garcia, Marta Marina Perez-Alonso, Rayko Halitschke, M Estrella Santamaria","doi":"10.1111/pce.70105","DOIUrl":"https://doi.org/10.1111/pce.70105","url":null,"abstract":"<p><p>Seed defence priming is emerging as a novel, cost-efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence-growth trade-off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive. Here, we investigated seed priming as a mitigator of the compromise between growth and defence in Arabidopsis thaliana upon pest infestation, focusing on its molecular dynamics. After studying the effect of a set of seed priming agents on plant resistance and growth, and once an effective elicitor was identified, a combined -omics approach was employed to decipher the molecular mechanisms underlying that regulation. We found that seed priming with 0.1 mM methyl jasmonate effectively boosted plant defence with no obvious fitness penalty as a result of a fine-tune regulation between transcriptome and metabolome. The basal state of readiness of primed plants was characterized by reduced stomatal aperture, high transcriptomic variation, increased sugar content and enhanced translational rate. Upon pest infestation, primed plants exhibited herbivore-specific molecular responses, with the phenylpropanoid pathway showing particular relevance. These findings demonstrate that methyl jasmonate seed priming can enhance pest-tailored defences in plants without incurring any obvious fitness penalty.</p>","PeriodicalId":222,"journal":{"name":"Plant, Cell & Environment","volume":" ","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144787927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Study of Model-Informed Drug Development of a Novel PCSK9 Antisense Oligonucleotide. Part 2: Phase 2 to Phase 3.","authors":"Jane Knöchel, Catarina Nilsson, Björn Carlsson, Alexis Hofherr, Per Johanson, Tina Rydén-Bergsten, Bengt Hamrén, Dinko Rekić","doi":"10.1002/psp4.70076","DOIUrl":"https://doi.org/10.1002/psp4.70076","url":null,"abstract":"<p><p>In this second part of a case study on the practical use of model-informed drug development (MIDD), we describe the clinical development of AZD8233, a novel proprotein convertase subtilisin/kexin type 9 (PCSK9) antisense oligonucleotide, from phase 2b to the start of phase 3. The case study exemplifies the use of MIDD to answer key design questions for the phase 3 program, including the design of a pivotal phase 3 study, a head-to-head study, and a cardiovascular outcome study informed by model-averaging analysis. Extensive phase 3 study simulations assessed the impact of drop-out, readout timing, dose frequency, and analysis method on study outcomes. The final phase 3 design assumed around 1% monthly drop-out (based on other PCSK9 inhibitor trials), used an EMA/FDA-approved analysis method, and set the primary readout at week 16. A simulated study predicted a reduction in low-density lipoprotein cholesterol (LDL-C) by week 16 of -69% with AZD8233 60 mg every 4 weeks. A virtual head-to-head study showed AZD8233 lowered LDL-C by 27% more than an active competitor (inclisiran) at day 270. Predicted cardiovascular relative risk reduction (RRR) for AZD8233 on top of statins ranged from 24% to 49% based on model choice; a model-averaging approach predicted an RRR of 27% assuming 63% LDL-C reduction from a 130 mg/dL baseline. This case study highlights the importance of cross-functional collaboration and other key MIDD enablers to ensure that MIDD extends beyond a simple simulation exercise and is instead considered an integral part of drug development dedicated to quantitative decision making.</p>","PeriodicalId":10774,"journal":{"name":"CPT: Pharmacometrics & Systems Pharmacology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144788476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting Systemic and Liver Bosentan Exposure Using Physiologically-Based Pharmacokinetic Modeling.","authors":"Miao-Chan Huang, Julia Macente, Sofie Heylen, Chen Ning, Kristof De Vos, Neel Deferm, Pieter Annaert","doi":"10.1002/psp4.70085","DOIUrl":"https://doi.org/10.1002/psp4.70085","url":null,"abstract":"<p><p>Bosentan is the first approved oral medication for pulmonary arterial hypertension, yet the black-box warning on its labeling implies a substantial risk of liver injury associated with bosentan exposure. The risk assessment of bosentan-induced liver injury requires a thorough understanding of the underlying mechanisms, for which there is accumulating evidence. Integrating these mechanisms with clinical liver bosentan concentration would enable a more dynamic and relevant risk assessment. This study designed a workflow of physiologically-based pharmacokinetic (PBPK) model development to capture bosentan's hepatic disposition and predict the (intra)hepatic bosentan exposure. Specifically, clinical plasma and excretion data of bosentan were used to minimize the uncertainty in estimating the hepatic clearance. The model predictions were well overlapped with observations in the systemic circulation and excretion. Furthermore, the model-derived intrinsic hepatic clearance was comparable with the one derived from a clinical study. These results reflected confidence in the model's capability to predict hepatic bosentan exposure. The model-simulated steady-state unbound exposure to bosentan in hepatocytes and liver tissue ranged from 1.65 to 34.1 ng/mL following twice-daily 125-mg oral doses. The ratio of the simulated unbound concentration between the liver matrices and systemic plasma was between 0.80 and 2.93 across the therapeutic dosing regimens. In summary, a bosentan PBPK model was successfully developed with the designed workflow and was able to predict the hepatic disposition of bosentan. The developed model can be applied to generate hepatic bosentan exposure that bridges the toxicological mechanistic findings from in vitro to in vivo, assisting in risk assessment.</p>","PeriodicalId":10774,"journal":{"name":"CPT: Pharmacometrics & Systems Pharmacology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144788478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient and Surgeon-Reported Satisfaction With Reconstruction Following Superficial Parotidectomy: A Systematic Review and Meta-Analysis","authors":"Jacob S. Brady,&nbsp;G. Nina Lu,&nbsp;Peter M. Vila,&nbsp;Zain H. Rizvi","doi":"10.1002/lio2.70208","DOIUrl":"https://doi.org/10.1002/lio2.70208","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>(1) Assess current methods for the collection of patient- and surgeon-reported outcomes after superficial parotidectomy reconstruction. (2) Determine which post-parotidectomy reconstructive method provides the highest degree of patient satisfaction.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>PRISMA guidelines were followed for article identification and selection. A total of 17 peer-reviewed articles including 898 patients were included in the study. Outcome data was mathematically harmonized across studies to allow statistical analysis. Random effects meta-analysis of proportions was performed. The Freeman-Tukey Double Arcsine method was used to calculate the pooled estimate, or rate for each analyzed outcome.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>No standardized or previously validated instrument was used to collect patient satisfaction data following superficial parotidectomy reconstruction in any of the included studies. After data harmonization, overall patient satisfaction was 93% when no reconstruction was performed, compared to 97% for sternocleidomastoid flap (SCM), and 100% for superficial muscular aponeurotic system flap (SMAS). Patient satisfaction of symmetry was 41% when no reconstruction was performed, compared to 65% for SMAS, 95% for free fat graft, and 96% for SCM.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Reporting methods for patient satisfaction with appearance and symmetry after superficial parotidectomy and reconstruction are heterogeneous and non-standardized. Artificially harmonized data demonstrate that patient-reported outcomes of satisfaction and symmetry were improved following any form of reconstruction after parotidectomy, and patients reported symmetry-specific satisfaction was less when SMAS reconstruction was performed. Validated and objective instruments should be utilized to determine the optimal approach to facial reconstruction after superficial parotidectomy to maximize patient-centered outcomes.</p>\u0000 \u0000 <p><b>Level of Evidence:</b> 3.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70208","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current and Emerging Autoantibodies in Ulcerative Colitis","authors":"Erick A. Mendieta-Escalante,&nbsp;Klaas Nico Faber,&nbsp;Gerard Dijkstra","doi":"10.1002/eji.202451721","DOIUrl":"https://doi.org/10.1002/eji.202451721","url":null,"abstract":"<p>Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by immune dysregulation and epithelial barrier dysfunction. Circulating autoantibodies have been observed in many patients, suggesting a role in disease pathogenesis and progression. Atypical anti-neutrophil cytoplasmic antibodies (a-ANCAs), anti-goblet cell antibodies (GAB), and anti-integrin αvβ6 antibodies have emerged as promising biomarkers for UC diagnosis, disease monitoring, and therapeutic response prediction. a-ANCAs are detected in up to 80% of UC patients, but their precise antigenic targets remain unclear. Evidence suggests their reactivity may involve neutrophil extracellular traps (NETs) and DNA–protein complexes, distinguishing them from ANCAs in vasculitis. GAB may contribute to mucus layer depletion and epithelial dysfunction. Anti-integrin αvβ6 antibodies have demonstrated high specificity for UC related to disease severity and potential for early detection.</p><p>Despite the diagnostic potential of these autoantibodies, lack of standardization, variability in detection methods, unclear binding sites, and lack of relevant clinical studies limit their use in clinical practice. Advances in epitope mapping, flow cytometry, and high-throughput immunoassays are promising approaches. We review the role of these autoantibodies in UC pathogenesis, highlight recent developments, and discuss their potential as biomarkers for improving diagnosis, disease monitoring, and personalized treatment strategies for UC patients.</p>","PeriodicalId":165,"journal":{"name":"European Journal of Immunology","volume":"55 8","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/eji.202451721","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eco-Friendly CMC/TKP Hydrogel: Design and Optimization for Dye Removal from Aqueous Solutions","authors":"Komal Nandal,&nbsp;Prince Preet Kaur,&nbsp;Rajeev Jindal","doi":"10.1002/slct.202502180","DOIUrl":"https://doi.org/10.1002/slct.202502180","url":null,"abstract":"<p>Toxic dyes in wastewater represent serious environmental and health hazards, necessitating the development of efficient and sustainable remediation strategies. Conventional dye removal techniques are often limited by high costs and low efficiency, underscoring the need for eco-friendly and cost-effective alternatives. In this study, a cross-linked three-dimensional (3D) hydrogel composed of carboxymethyl cellulose and tamarind kernel powder (TKP) was synthesized and optimized, achieving a maximum swelling capacity of 1508%. The hydrogel's structural, morphological, and thermal properties were characterized via FTIR, XRD, FESEM, and TGA analyses. Its adsorption performance was evaluated using methylene blue (cationic dye) and rose Bengal (anionic dye) under varying parameters, including initial dye concentration, pH, temperature, ionic strength, and adsorbent dosage. The hydrogel exhibited maximum adsorption capacities of 353.0 mg/g for RB and 404.8 mg/g for MB. Adsorption followed pseudo-second-order kinetics and fitted well with the Langmuir isotherm model, suggesting monolayer adsorption. Thermodynamic parameters revealed the adsorption process to be spontaneous and exothermic, with Gibbs free energy changes of −4.492 kJ/mol for RB and −4.478 kJ/mol for MB. Additionally, the hydrogel demonstrated good reusability, supporting its potential for practical wastewater treatment applications.</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 30","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Energy-Efficient UAV-Assisted Covert Communication in WSN With Finite Blocklength","authors":"Wennan Chu,&nbsp;Shuang Zhang,&nbsp;Yining Xu,&nbsp;Xingyu Yao,&nbsp;Yanan Gao,&nbsp;Weichen Cai,&nbsp;Wen Tian,&nbsp;Huaifeng Shi","doi":"10.1049/ell2.70366","DOIUrl":"https://doi.org/10.1049/ell2.70366","url":null,"abstract":"<p>Wireless sensor network (WSN) is a critical component of the Internet of Things. To address the security threats in WSN, finite blocklength-based covert communication has emerged as a promising method to protect data from eavesdropping and improve reliability under practical constraints. However, this security communication method poses significant energy challenges, especially in three-dimensional WSNs with non-line-of-sight communication and strict covert constraints. To address this issue, we propose a jointly optimizing UAV trajectory and wake-up scheduling method (JOUTWUSM) for finite blocklength covert communication in WSN. By jointly optimizing the UAV's trajectory and wake-up scheduling, the proposed method effectively balances energy efficiency and communication reliability under finite blocklength covert communication constraints. Simulation results demonstrate that the proposed JOUTWUSM significantly reduces energy consumption and improves data collection efficiency.</p>","PeriodicalId":11556,"journal":{"name":"Electronics Letters","volume":"61 1","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/ell2.70366","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144782253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biphasic Ni-MXene Quantum-Confined Nanostructures: A Versatile Janus Platform for Advanced Energy Storage and Catalytic Oxidations.","authors":"Lagnamayee Mohapatra, Subir Kumar Pati, Dhananjaya Patra, Kyung-Hwan Jin, Sungjune Park, Seung Hwa Yoo","doi":"10.1002/adma.202505852","DOIUrl":"https://doi.org/10.1002/adma.202505852","url":null,"abstract":"<p><p>The demand for sustainable energy storage and ecofriendly catalysts has intensified the search for advanced multifunctional materials. Herein, this work presents the synthesis and characterization of Janus Ni-MXene quantum dot (Ni-MJQD), a novel material architecture that exhibits high performance in supercapacitor and catalytic applications. A Ni-MJQD cathode delivers an impressive gravimetric specific capacity of 168.75 mAh g^-1 at 3 A g^-1, and its Janus structure optimizes the balance between capacity and ion diffusion. In an asymmetric hybrid supercapacitor (AHSC) with a porous activated carbon (PAC) anode, it achieves an energy density of 54.22 Wh kg^-1, a power density of 1599 W kg^-1, and 88% capacity retention over 20 000 cycles. As a catalyst, the Ni-MJQD also exhibits high activity in benzyl alcohol oxidation, reaching 95% conversion and 98.4% selectivity for benzaldehyde, with the largest turnover frequency of 8.8825 × 10^-3 moles g^-1 h^-1 using peroxymonosulfate (PMS) as an oxidant. Mechanistic analysis reveals contributions from both radical and nonradical pathways. These findings emphasize the unique potential of the Ni-MJQD electrodes for sustainable energy storage and green synthesis applications.</p>","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":" ","pages":"e05852"},"PeriodicalIF":26.8,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144787891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prolonged Water-Only Fasting Followed by a Whole-Plant-Food Diet Promotes Fat-Free Mass Recovery and Continued Fat Mass Loss in Adults With Overweight or Obesity.","authors":"Sahmla Gabriel, Mackson Ncube, David M Goldman, Eugene Scharf, Alan C Goldhamer, Toshia R Myers","doi":"10.1002/osp4.70086","DOIUrl":"https://doi.org/10.1002/osp4.70086","url":null,"abstract":"<p><strong>Introduction: </strong>Conventional weight-loss strategies often result in inadequate fat loss, poor sustainability, and unintended lean mass loss. Prolonged water-only fasting followed by dietary change may offer an effective alternative, but its impact on body composition remains underexplored.</p><p><strong>Methods: </strong>This secondary analysis utilized dual-energy X-ray absorptiometry (DXA) to assess changes in fat-free mass (FFM), fat mass (FM), and bone mineral content (BMC) in adults [median (IQR) age: 62 (15) years with overweight or obesity. Participants underwent a median (IQR) of 14 (6) days of water-only fasting, followed by 6 (3) days of food reintroduction with a whole-plant-food diet and a subsequent maintenance period of 45 (5) days. Study visits occurred at baseline and at the end of each period.</p><p><strong>Results: </strong>At end of fasting, FFM accounted for 74% of total BW lost during fasting. However, at the follow-up visit, the median (IQR) percentage change in total BW, FFM, FM, and visceral adipose tissue (VAT) mass from baseline was -8.2 (5.2), -4.4 (5.6), -14.7 (8.9), -15.8 (12.8) %, respectively. At follow-up, FM loss accounted for 67% of the total BW lost. BMC remained unchanged across all study visits.</p><p><strong>Conclusions: </strong>This protocol produced sustained FM loss, specifically VAT mass, and FFM recovery, suggesting it may support effective weight management.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"11 4","pages":"e70086"},"PeriodicalIF":1.9,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12322586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing expert elicitation techniques through participatory mapping: Application to marine environment assessments in Palawan, Philippines","authors":"Billy Tusker Haworth,&nbsp;Eleanor Bruce,&nbsp;Glenda M. Cadigal,&nbsp;John Martin S. Caligdong,&nbsp;James Green,&nbsp;Elaine Baker","doi":"10.1002/geo2.70019","DOIUrl":"https://doi.org/10.1002/geo2.70019","url":null,"abstract":"<p>State of the Marine Environment (SoME) reporting provides an effective mechanism for countries to collate available evidence to highlight pressures and identify indicators of current and changing conditions in marine environments. Expert elicitation (EE) (or expert knowledge elicitation) techniques have been used to ensure a consultative and comprehensive process for achieving these broad seascape assessments, especially in data-poor environments. EE is a consensus methodology that draws on the collective wisdom of known field experts to assist in filling data and knowledge gaps to inform policy decision-making in the absence of other supporting evidence. To date, EE methods for SoME reporting have been limited in their ability to capture and represent data on spatially variable phenomena. The absence of geographic information instils biases and inaccuracies in EE data by aggregating experts' contributions to broad spatial scales, limiting their usefulness in formulating spatially targeted policies operative at scales appropriate for the phenomena of interest. In this paper, a participatory mapping methodology to enhance EE data and processes through inclusion of spatially explicit contributions from experts is described. Paper-based participatory mapping was introduced into an EE workshop for SoME assessment of the archipelagic province of Palawan, Philippines. Analysis of the participatory mapping method was based on observations of the workshop activities in practice, participant feedback, and the authors' appraisal and analysis of the spatial information provided. Integrating participatory mapping within EE techniques enables the representation of expert knowledge and perspectives in a geographic context. In mapping localised pressures and identifying spatial trends expressed in the condition scores across different assessment parameters, participatory mapping can facilitate prioritising locations for further ground-truthing, finer-scale scientific investigation, and conservation effort. An integrated participatory mapping approach has the potential to extend the outcomes of marine environment assessments and better reflect place-based issues within SoME reporting.</p>","PeriodicalId":44089,"journal":{"name":"Geo-Geography and Environment","volume":"12 2","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/geo2.70019","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144782587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}