Wiley最新文献

{"title":"Titanium‒Nickel Dual Active Sites Enabled Reversible Hydrogen Storage of Magnesium at 180 °C with Exceptional Cycle Stability (Adv. Mater. 26/2025)","authors":"Haotian Guan,&nbsp;Jiang Liu,&nbsp;Xuan Sun,&nbsp;Yangfan Lu,&nbsp;Hongyuan Wang,&nbsp;Qun Luo,&nbsp;Qian Li,&nbsp;Fusheng Pan","doi":"10.1002/adma.202570178","DOIUrl":"https://doi.org/10.1002/adma.202570178","url":null,"abstract":"<p><b>Mg-Based Hydrogen Storage Materials</b></p><p>Hydrogen storage of magnesium involves complicated reaction kinetics at the gas-solid interfaces. Utilizing Ti-MgO and Mg₂Ni multiphase catalysts, hydrogen adsorption, dissociation, diffusion and nucleation steps are simultaneously accelerated. It enables a reversible hydrogen storage reaction at 180 °C at least for 1000 cycles. More details can be found in article number 2500178 by Yangfan Lu, Qun Luo, Qian Li, and co-workers.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"37 26","pages":""},"PeriodicalIF":27.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adma.202570178","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144550995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroprotective Potential of Human Platelet Lysate in Parkinson's Disease: Insights Into Oxidative Stress, Mitochondrial Dysfunction, Cell Death, and Reactive Gliosis in Experimental Models","authors":"Samir Kumar Beura,&nbsp;Abhishek Kumar Maurya,&nbsp;Sneha Kumari,&nbsp;Divya Soni,&nbsp;Prajjwal Sharma,&nbsp;Nisha Yadav,&nbsp;Abhishek Ramachandra Panigrahi,&nbsp;Pooja Yadav,&nbsp;Puneet Kumar,&nbsp;Dibbanti Harikrishna Reddy,&nbsp;Debapriya Garabadu,&nbsp;Sunil Kumar Singh","doi":"10.1002/biot.70064","DOIUrl":"https://doi.org/10.1002/biot.70064","url":null,"abstract":"<div>\u0000 \u0000 <p>Parkinson's disease (PD) entails complex pathology, with current treatments managing symptoms but failing to halt neurodegeneration. Preclinical evidence suggests human platelet lysate (HPL) from healthy donors as a neuroprotective candidate due to its rich neurotrophic content, though its potential in PD models remains largely underexplored. In this study, we present substantial experimental findings demonstrating the neuroprotective effects of HPL administration in both rotenone (ROT)-induced in vitro as well as in vivo models of PD. Our findings reveal that freshly prepared HPL from healthy humans, obtained through freeze-thaw cell lysis followed by heat treatment and ultrafiltration, exhibits significant neuroprotective effects. This protection, evidenced by the attenuation of ROT-induced cell death in SH-SY5Y cells, was mediated through the reduction of oxidative stress, mitochondrial dysfunction, calcium dysregulation, and apoptosis. Additionally, in PD rats, intranasal HPL administration at various doses counteracted ROT-induced weight loss, improved motor function, balance, and grip strength, and alleviated anxiety, stress, and depression. Additionally, HPL promoted neuronal regeneration, suppressed astrocytic and microglial activation in the substantia nigra and striatum, enhanced antioxidant enzyme expression (glutathione and catalase), and reduced pro-oxidants (malondialdehyde and nitric oxide). These findings underscore HPL's potential as a promising therapeutic strategy for PD, representing a significant advancement in regenerative medicine.</p>\u0000 </div>","PeriodicalId":134,"journal":{"name":"Biotechnology Journal","volume":"20 7","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Near-Infrared Fluorescent Single-Walled Carbon Nanotubes for Biosensing (Small 26/2025)","authors":"Srestha Basu,&nbsp;Gili Bisker","doi":"10.1002/smll.202570203","DOIUrl":"https://doi.org/10.1002/smll.202570203","url":null,"abstract":"<p><b>Carbon Nanotube Biosensors</b></p><p>Near-infrared fluorescent single-walled carbon nanotubes (SWCNTs) enable real-time, selective, and sensitive detection of biomolecular targets in complex environments. Through tailored surface functionalization, these nanosensors harness the unique optical properties of SWCNTs for a broad range of biosensing applications. More in article number 2502542, Srestha Basu and Gili Bisker.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":228,"journal":{"name":"Small","volume":"21 26","pages":""},"PeriodicalIF":13.0,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/smll.202570203","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Wireless Cortical Surface Implant for Diagnosing and Alleviating Parkinson's Disease Symptoms in Freely Moving Animals (Adv. Healthcare Mater. 17/2025)","authors":"Hongseong Shin,&nbsp;Kyungtae Kim,&nbsp;Jaeseung Lee,&nbsp;Johyeon Nam,&nbsp;Eunha Baeg,&nbsp;Chaeyeon You,&nbsp;Hanseul Choi,&nbsp;Minji Kim,&nbsp;Chun Kee Chung,&nbsp;Jae Geun Kim,&nbsp;Jong Hyun Ahn,&nbsp;Miryung Han,&nbsp;Jibum Kim,&nbsp;Sungchil Yang,&nbsp;Sung Q Lee,&nbsp;Sunggu Yang","doi":"10.1002/adhm.202570101","DOIUrl":"https://doi.org/10.1002/adhm.202570101","url":null,"abstract":"<p><b>Parkinson's Disease</b></p><p>Wireless graphene-based cortical surface implant restores motor function in Parkinsonian rats by recording pathogenic beta–gamma oscillations and delivering on-demand high-frequency stimulation that rebalances delta rhythms, strengthens mGluR5- and D5R-mediated synaptic plasticity, and upregulates glutamatergic genes. The flexible, biocompatible, minimally invasive system demonstrates integrated real-time diagnosis and therapy for neurodegenerative disorders across multiple freely moving animals. More details can be found in article 2405179 by Sungchil Yang, Sung Q Lee, Sunggu Yang, and co-workers.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":113,"journal":{"name":"Advanced Healthcare Materials","volume":"14 17","pages":""},"PeriodicalIF":10.0,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adhm.202570101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Broadband Enhancement of Third Harmonic Generation Based on the Strong Coupling Between all-dielectric Metasurfaces and Epsilon-Near-Zero Modes (Advanced Optical Materials 19/2025)","authors":"Ai-Yin Liu,&nbsp;Kuang-I Lin,&nbsp;Snow H. Tseng,&nbsp;Hui-Hsin Hsiao","doi":"10.1002/adom.70023","DOIUrl":"https://doi.org/10.1002/adom.70023","url":null,"abstract":"<p><b>Ultrabroadband Nonlinear Metasurfaces</b></p><p>In article 2500084, Hui-Hsin Hsiao and co-workers investigate the interplay between Mie resonances, quasi-bound states in the continuum, and epsilon-near-zero (ENZ) modes in a hybrid system composed of all-dielectric metasurfaces atop an ultrathin ITO film. The strong coupling of hybridized Mie-ENZ modes dominates the nonlinear enhancement with an ultrabroadband third-harmonic generation spanning the 1230–1600 nm wavelength range.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":116,"journal":{"name":"Advanced Optical Materials","volume":"13 19","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adom.70023","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Front Cover: Enhanced Reversibility of Li-Rich Binary Oxide Cathodes through Synergistic Interfacial Regulation for Improved Charge Transfer Kinetics at High Depth of Charge/Discharge (ChemElectroChem 13/2025)","authors":"Qing Zhang,&nbsp;Jiaoyang Cheng,&nbsp;Jinxin Cao,&nbsp;Fang Lian","doi":"10.1002/celc.70009","DOIUrl":"https://doi.org/10.1002/celc.70009","url":null,"abstract":"<p><b>The illustration presents</b> LATP and PANI collaborative interface regulation of Li-rich binary oxides, achieving remarkable enhancement in initial Coulombic efficiency and rate capability of cathode materials. The Mobius ring embodies the infinite cycling potential of modified materials. The inset (top-left/right) highlights the ion-electron dual conductor coating’s reinforcement effect on Li⁺ transport during deep charge/discharge. Synergistic mechanisms and modification principles are detailed in the Research Article by Fang Lian and co-workers (DOI: 10.1002/celc.202500045).\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"12 13","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/celc.70009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NIR-Induced Photoswitching Hybrid DNA Nanoconstruct-Based Drug Delivery System for Spatiotemporal Control of Stem Cell Fate (Small 26/2025)","authors":"Thanapat Pongkulapa,&nbsp;Ji Hye Yum,&nbsp;Callan D. McLoughlin,&nbsp;Brandon Conklin,&nbsp;Tomotaka Kumagai,&nbsp;Li Ling Goldston,&nbsp;Hiroshi Sugiyama,&nbsp;Soyoung Park,&nbsp;Ki-Bum Lee","doi":"10.1002/smll.202570207","DOIUrl":"https://doi.org/10.1002/smll.202570207","url":null,"abstract":"<p><b>Drug Delivery</b></p><p>Within nanomedicine, efficient control and predictable release of drug payloads are crucial to therapeutic efficacy. Opposing passive drug release, light is an attractive tool for controlling biological functions, offering unparalleled temporal and spatial precision. Leveraging this potential, the combination of photo-responsive DNA nanostructures and up-conversion nanoparticles capable of harnessing near-infrared signals presents a promising avenue for finely tuning dynamic and intricate stem cell fate regulation. More in article number 2409530, Soyoung Park, Ki-Bum Lee, and co-workers.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":228,"journal":{"name":"Small","volume":"21 26","pages":""},"PeriodicalIF":13.0,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/smll.202570207","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Twist of Ferroelectric Smectic Blocks in Polar Fluids (Adv. Mater. 26/2025)","authors":"Hiroya Nishikawa,&nbsp;Yasushi Okumura,&nbsp;Dennis Kwaria,&nbsp;Atsuko Nihonyanagi,&nbsp;Fumito Araoka","doi":"10.1002/adma.202570179","DOIUrl":"https://doi.org/10.1002/adma.202570179","url":null,"abstract":"<p><b>Spontaneous Twist of Ferroelectric Smectic Blocks</b></p><p>The ferroelectric nematic (NF) phase in achiral rod-shape mesogens is known to exhibit chiral ground state (CGS) due to the polarization escape. In this study, Hiroya Nishikawa, Fumito Araoka, and co-workers found such CGS as twisting of bulky smectic blocks in a ferroelectric smectic phase transited directly from the NF phase. More details can be found in article number 2501946.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":114,"journal":{"name":"Advanced Materials","volume":"37 26","pages":""},"PeriodicalIF":27.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adma.202570179","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved and Controlled Singlet Oxygen Generation by Photoswitchable Organic Delayed Fluorescence Emitter (Advanced Optical Materials 19/2025)","authors":"Sayan Kumar Bag,&nbsp;Arnab Mandal,&nbsp;Bijan Mondal,&nbsp;Abhijit Patra,&nbsp;Arunabha Thakur","doi":"10.1002/adom.70069","DOIUrl":"https://doi.org/10.1002/adom.70069","url":null,"abstract":"<p><b>Photooxidation</b></p><p>Developed a pure organic molecule for improved and efficient singlet oxygen (¹O₂) generation in solution and in solid state in presence of visible light. The generated ¹O₂ from ambient molecular oxygen has been utilized for the controlled photooxidation of several organic species. More details can be found in article 2500620 by Arunabha Thakur and co-workers.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":116,"journal":{"name":"Advanced Optical Materials","volume":"13 19","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adom.70069","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Residual pulmonary hypertension and clinical outcomes in acute decompensated heart failure patients stratified by left ventricular ejection fraction.","authors":"Toshikazu D Tanaka, Yasuyuki Shiraishi, Ryeonshi Kang, Takashi Kohno, Satoshi Shoji, Toraaki Okuyama, Yuhei Oi, Ayumi Goda, Ryo Nakamaru, Yuji Nagatomo, Mitsunobu Kitamura, Munehisa Sakamoto, Michiru Nomoto, Atsushi Mizuno, Tomohisa Nagoshi, Shun Kohsaka, Tsutomu Yoshikawa","doi":"10.1002/ejhf.3755","DOIUrl":"https://doi.org/10.1002/ejhf.3755","url":null,"abstract":"<p><strong>Aims: </strong>The precise outcomes for patients with residual pulmonary hypertension (PH) following the optimized treatment of acute decompensated heart failure (ADHF) remain poorly understood. This study aimed to investigate the prognostic association of PH, categorized according to left ventricular ejection fraction (LVEF), in hospitalized ADHF patients.</p><p><strong>Methods and results: </strong>The WET-HF registry is a multicentre, prospective cohort ADHF registry. Patients were classified into four groups according to tricuspid regurgitation velocity (TRV) and LVEF. PH was defined as peak TRV >2.8 m/s. The primary endpoint was a composite of all-cause mortality and heart failure (HF) rehospitalization at 2 years. In total, 1702 patients had nonPH-HF with LVEF <50% (n = 689 [40.5%]), PH-HF with LVEF <50% (n = 291 [17.1%]), nonPH-HF with LVEF ≥50% (n = 453 [26.6%]), and PH-HF with LVEF ≥50% (n = 269 [15.8%]). A significant difference in the composite endpoint was observed between patients with and without PH (42.3% vs. 30.4%, p < 0.001), with no significant interaction between PH and LVEF. Notably, in the nonPH-HF group, there were significant differences in clinical outcomes between patients with more than 30% B-type natriuretic peptide (BNP) improvement and those with less (composite endpoint 27.5% vs. 41.8%, p < 0.001; all-cause mortality 9.4% vs. 24.6%, p < 0.001; HF rehospitalization 20.2% vs. 32.8%, p = 0.001). However, no such difference was evident in the PH-HF group.</p><p><strong>Conclusions: </strong>The prognostic importance of residual PH was comparable across both HF with reduced and preserved ejection fraction patients. While the prognostic significance of BNP improvement on clinical outcomes was attenuated in the presence of residual PH, utilizing residual PH for risk stratification effectively identified patients at increased risk of mortality and rehospitalization following ADHF, irrespective of their LVEF.</p>","PeriodicalId":164,"journal":{"name":"European Journal of Heart Failure","volume":" ","pages":""},"PeriodicalIF":16.9,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144558553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}