Wiley最新文献

{"title":"Diel Bacterioplankton Community Dynamics Under Contrasting Light Regimes","authors":"Sofia Papadopoulou,&nbsp;Annika Linkhorst,&nbsp;John Paul Balmonte,&nbsp;Bianka Csitári,&nbsp;Tamás Felföldi,&nbsp;Zsuzsanna Márton,&nbsp;Maliheh Mershad,&nbsp;Attila Szabó,&nbsp;Anders Torstensson,&nbsp;Stefan Bertilsson,&nbsp;Anna J. Székely","doi":"10.1111/1758-2229.70099","DOIUrl":"https://doi.org/10.1111/1758-2229.70099","url":null,"abstract":"<p>In the Boreal region, extreme seasonal variations in day–night length expose communities to dynamic light and temperature fluctuations. Freshwater bacterioplankton, representing key ecosystem components, faces climate-driven shifts; yet the fixed day-length patterns determined by latitude underscore the importance of studying light's role in predicting ecosystem responses. We investigated bacterial community composition in a brown peat bog and a clear oligotrophic lake across seasons with contrasting light regimes: the summer solstice (&gt; 20 h of daylight) and the autumn equinox (equal day-night length). Using amplicon sequencing of 16S rRNA transcripts, alongside measurements of physicochemical parameters, organic matter characterisation and dissolved carbon dioxide and methane gas measurements, we found no diel cycling in the lake during either period or in the peat bog near the summer solstice. However, the structure of bacterial peat bog communities exhibited cyclic changes over diel cycles at the autumn equinox. Twelve amplicon sequence variants, including both phototrophic and heterotrophic taxa, increased in abundance at all measured morning sampling times. These findings provide valuable insights into the diel patterns of boreal lentic habitats and their bacterioplankton communities, highlighting the absence of diel fluctuations in some systems and seasons, while revealing cyclic dynamics in others, driven by conditionally rare taxa.</p>","PeriodicalId":163,"journal":{"name":"Environmental Microbiology Reports","volume":"17 3","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1758-2229.70099","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and Properties of Trinitromethyl-1H-1,2,4-Triazole Bridging Nitropyrazole Energetic Salts","authors":"LingFeng Xie,&nbsp;Pingping Yi,&nbsp;Chenchen Lin,&nbsp;Xiaoyi Yi,&nbsp;Piao He,&nbsp;Tingwei Wang,&nbsp;Jianguo Zhang","doi":"10.1002/slct.202500047","DOIUrl":"https://doi.org/10.1002/slct.202500047","url":null,"abstract":"<p>The polynitroazole plays an important role in the design of high-energy density materials. A series of nitrogen-rich salts based on trinitromethyl-substituted 1<i>H</i>-1,2,4-triazole bridging nitropyrazole was prepared. These newly synthesized salts were fully characterized by chemical analysis (infrared, NMR, and mass spectroscopy) as well as experimental tests (thermostability and sensitivities). Their detonation properties (detonation velocity, detonation pressure, etc.) were determined by the EXPLO5 program on the basis of density and heat of formation. These nitrogen-rich salts show moderate thermostabilities and low sensitivities (IS ≥ 10 J, FS ≥ 252 N) due to intermolecular hydrogen bonding interactions. The most promising high-energy insensitive compound is salt 2, which possesses a high density (1.80 g cm⁻³), relatively high thermal stability (149 °C), low sensitivity (IS = 30 J, FS = 252 N), good detonation velocity (8997 m s⁻¹) and detonation pressure (36.7 GPa) which is comparable to cyclotrimethylenetrinitramine (RDX). This study supports the efficiency of utilizing nitrogen-rich salts combined with trinitromethyl-substituted systems in the development of new high-energy, insensitive energetic materials.</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 18","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The emerging role of lymphocyte-activation gene 3 targeting in the treatment of solid malignancies","authors":"Vinay K. Giri MD,&nbsp;David F. McDermott MD,&nbsp;Jacob Zaemes MD","doi":"10.1002/cncr.35892","DOIUrl":"https://doi.org/10.1002/cncr.35892","url":null,"abstract":"<p>PD-(L)1–based immune checkpoint inhibitor therapies have profoundly impacted the treatment of many solid malignancies. Although the addition of CTLA-4 checkpoint inhibitors can enhance anticancer activity, it also significantly increases the rate of immune-related adverse events. Therefore, there has been much interest in identifying additional immune checkpoints to improve the outcomes seen with PD-1–based therapy while minimizing additional side effects. One such target, lymphocyte-activation gene 3 (LAG-3), has long been recognized as an important inhibitor of T-cell function via modulation of the T-cell receptor pathway. Several drugs targeting LAG-3 have been developed, including most prominently the monoclonal antibody relatlimab. To date, the most significant demonstration of efficacy in targeting LAG-3 has been the use of relatlimab with the PD-1 inhibitor nivolumab in the treatment of advanced melanoma. The combination of nivolumab plus relatlimab is more efficacious compared to PD-1 inhibition alone, as has been previously seen with the combination of CTLA-4 inhibitor ipilimumab with nivolumab. However, nivolumab plus relatlimab offers a potentially more favorable toxicity profile. Here, the authors review the mechanism of the LAG-3 pathway and its rationale as a target for anticancer therapy as well as currently available data regarding the use of LAG-3 agents in treating melanoma and other solid tumors. Other investigational agents that target LAG-3 via novel mechanisms are also reviewed.</p>","PeriodicalId":138,"journal":{"name":"Cancer","volume":"131 10","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143925735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fungal Energy Channelling Sustains Soil Animal Communities Across Forest Types and Regions","authors":"André Junggebauer,&nbsp;Melissa Jüds,&nbsp;Bernhard Klarner,&nbsp;Jens Dyckmans,&nbsp;Melanie M. Pollierer,&nbsp;Stefan Scheu","doi":"10.1111/ele.70122","DOIUrl":"https://doi.org/10.1111/ele.70122","url":null,"abstract":"<p>Emerging evidence suggests that microbivory prevails in soil animal communities, yet the relative importance of bacteria, fungi and plants as basal resource energy channels across taxa and forest types remains unstudied. We developed a novel framework combining stable isotope analysis of essential amino acids (eAAs) and energy fluxes to quantify basal resource contributions and trophic positions of meso- and macrofauna detritivores (Collembola, Oribatida, Diplopoda, Isopoda, Lumbricidae) and predators (Mesostigmata, Chilopoda) in 48 forest sites of different management intensity across Germany. Fungal energy channelling dominated, with the highest energy fluxes and 73% fungal eAAs across forests and regions. Chilopoda, however, acquired more energy from bacteria and plants. Energy fluxes to Lumbricidae were highest, but decreased, alongside those to other macrofauna, in acidic forests. Trophic positions varied between regions, reflecting changes in community structure linked to regional factors. Our findings highlight the stability and pivotal role of fungal energy channelling for forest soil animal communities.</p>","PeriodicalId":161,"journal":{"name":"Ecology Letters","volume":"28 5","pages":""},"PeriodicalIF":7.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ele.70122","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adapting the Re-ID Challenge for Static Sensors","authors":"Avirath Sundaresan,&nbsp;Jason Parham,&nbsp;Jonathan Crall,&nbsp;Rosemary Warungu,&nbsp;Timothy Muthami,&nbsp;Jackson Miliko,&nbsp;Margaret Mwangi,&nbsp;Jason Holmberg,&nbsp;Tanya Berger-Wolf,&nbsp;Daniel Rubenstein,&nbsp;Charles Stewart,&nbsp;Sara Beery","doi":"10.1049/cvi2.70027","DOIUrl":"https://doi.org/10.1049/cvi2.70027","url":null,"abstract":"<p>The Grévy's zebra, an endangered species native to Kenya and southern Ethiopia, has been the target of sustained conservation efforts in recent years. Accurately monitoring Grévy's zebra populations is essential for ecologists to evaluate ongoing conservation initiatives. Recently, in both 2016 and 2018, a full census of the Grévy's zebra population was enabled by the Great Grévy's Rally (GGR), a citizen science event that combines teams of volunteers to capture data with computer vision algorithms that help experts estimate the number of individuals in the population. A complementary, scalable, cost-effective and long-term Grévy's population monitoring approach involves deploying a network of camera traps, which we have done at the Mpala Research Centre in Laikipia County, Kenya. In both scenarios, a substantial majority of the images of zebras are not usable for individual identification due to ‘in-the-wild’ imaging conditions—occlusions from vegetation or other animals, oblique views, low image quality and animals that appear in the far background and are thus too small to identify. Camera trap images, without an intelligent human photographer to select the framing and focus on the animals of interest, are of even poorer quality, with high rates of occlusion and high spatiotemporal similarity within image bursts. We employ an image filtering pipeline incorporating animal detection, species identification, viewpoint estimation, quality evaluation and temporal subsampling to compensate for these factors and obtain individual crops from camera trap and GGR images of suitable quality for re-ID. We then employ the local clusterings and their alternatives (LCA) algorithm, a hybrid computer vision and graph clustering method for animal re-ID, on the resulting high-quality crops. Our method processed images taken during GGR-16 and GGR-18 in Meru County, Kenya, into 4142 highly comparable annotations, requiring only 120 contrastive same-vs-different-individual decisions from a human reviewer to produce a population estimate of 349 individuals (within 4.6<span></span><math>\u0000 <semantics>\u0000 <mrow>\u0000 <mi>%</mi>\u0000 </mrow>\u0000 <annotation> $%$</annotation>\u0000 </semantics></math> of the ground truth count in Meru County). Our method also efficiently processed 8.9M unlabelled camera trap images from 70 camera traps at Mpala over 2 years into 685 encounters of 173 unique individuals, requiring only 331 contrastive decisions from a human reviewer.</p>","PeriodicalId":56304,"journal":{"name":"IET Computer Vision","volume":"19 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/cvi2.70027","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143925963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unsupervised Image Enhancement Method Based on Adaptation Region Divisions","authors":"Kaijun Zhou,&nbsp;Weiyi Yuan,&nbsp;Yemei Qin","doi":"10.1049/ipr2.70043","DOIUrl":"https://doi.org/10.1049/ipr2.70043","url":null,"abstract":"<p>This paper presents a novel image enhancement method that integrates traditional image processing techniques with deep learning frameworks. Initially, images are transformed from the red, green and blue (RGB) color space to the Lab color space, and the luminance component (L) is extracted to quantify texture. Subsequently, texture complexity is assessed using features derived from the gray-level co-occurrence matrix (GLCM), including contrast, correlation, homogeneity, and energy. These features are weighted to compute an overall texture complexity score, which facilitates the segmentation of the image into distinct regions. Regions characterized by simple textures are aggregated into larger segments, whereas regions with complex textures are subdivided into smaller segments. Following segmentation, histogram equalization is applied along with noise reduction and image enhancement via a convolutional autoencoder model. The model extracts relevant features and reduces dimensionality in the encoder phase, and reconstructs the image through the decoder. This methodology effectively preserves semantic information and enhances image clarity. Some experiments are conducted using the ExDark dataset, which comprises twelve categories, and the enhancement results are quantitatively evaluated using image quality metrics such as peak signal-to-noise ratio (PSNR), structural similarity index (SSIM), learned perceptual image patch similarity (LPIPS), and neural image quality evaluator (NIQE). Experimental results demonstrate that the proposed method significantly surpasses existing enhancement techniques in terms of image quality and visual perception, thereby affirming its efficacy in improving the visual quality and detail of low-light images. The implementation code will be made publicly available at: https://github.com/Winnie0320/Image-Enhancement-Method.</p>","PeriodicalId":56303,"journal":{"name":"IET Image Processing","volume":"19 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/ipr2.70043","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143925961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diel Bacterioplankton Community Dynamics Under Contrasting Light Regimes","authors":"Sofia Papadopoulou,&nbsp;Annika Linkhorst,&nbsp;John Paul Balmonte,&nbsp;Bianka Csitári,&nbsp;Tamás Felföldi,&nbsp;Zsuzsanna Márton,&nbsp;Maliheh Mershad,&nbsp;Attila Szabó,&nbsp;Anders Torstensson,&nbsp;Stefan Bertilsson,&nbsp;Anna J. Székely","doi":"10.1111/1758-2229.70099","DOIUrl":"https://doi.org/10.1111/1758-2229.70099","url":null,"abstract":"<p>In the Boreal region, extreme seasonal variations in day–night length expose communities to dynamic light and temperature fluctuations. Freshwater bacterioplankton, representing key ecosystem components, faces climate-driven shifts; yet the fixed day-length patterns determined by latitude underscore the importance of studying light's role in predicting ecosystem responses. We investigated bacterial community composition in a brown peat bog and a clear oligotrophic lake across seasons with contrasting light regimes: the summer solstice (&gt; 20 h of daylight) and the autumn equinox (equal day-night length). Using amplicon sequencing of 16S rRNA transcripts, alongside measurements of physicochemical parameters, organic matter characterisation and dissolved carbon dioxide and methane gas measurements, we found no diel cycling in the lake during either period or in the peat bog near the summer solstice. However, the structure of bacterial peat bog communities exhibited cyclic changes over diel cycles at the autumn equinox. Twelve amplicon sequence variants, including both phototrophic and heterotrophic taxa, increased in abundance at all measured morning sampling times. These findings provide valuable insights into the diel patterns of boreal lentic habitats and their bacterioplankton communities, highlighting the absence of diel fluctuations in some systems and seasons, while revealing cyclic dynamics in others, driven by conditionally rare taxa.</p>","PeriodicalId":163,"journal":{"name":"Environmental Microbiology Reports","volume":"17 3","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1758-2229.70099","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recognition of G-series Nerve Agents via Aryl─C─H Interactions with [6]Cycloparaphenylene: A Computational Study","authors":"Dipankar Das,&nbsp;Bishwajit Ganguly","doi":"10.1002/slct.202405508","DOIUrl":"https://doi.org/10.1002/slct.202405508","url":null,"abstract":"<p>Organophosphorus-containing chemical warfare agents known as nerve agents work by irreversibly inhibiting acetylcholinesterase, leading to overstimulation of cholinergic synapse followed by the cholinergic crisis and deterioration of neurotransmission. Therefore, the recognition of such nerve agents is crucial. We report conjugated hoop-shaped supramolecular [6]CPP as a host for encapsulating G-series nerve agents. The DFT calculated results revealed that the host [6]CPP forms a more stable encapsulated complex with the G-series nerve agent Tabun compared to the other nerve agents. This higher binding affinity of Tabun is governed by multiple noncovalent CH…π interactions with the electron-rich cavity of the host [6]CPP, which plays a pivotal role in fitting well inside the host cavity. The hydroxyl-substituted [6]CPP_OH showed an even larger binding affinity for the nerve agents. The atoms in molecule (AIM) and noncovalent interactions (NCI) have well corroborated the interactions of G-series nerve agents with [6]CPP host molecule. The energy decomposition analysis (EDA) suggests that the orbital contributions stabilize the formation of the complex between G-series nerve agents and the host molecules. The TD-DFT calculations and infrared spectral results suggest that the encapsulated nerve agents with host [6]CPP and [6]CPP_OH can be recognized for various applications.</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 18","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143925759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Recent Advancements of Niobium and Tantalum-Based Materials: From Design Engineering to Energy Storage Applications”","authors":"","doi":"10.1002/slct.202501581","DOIUrl":"https://doi.org/10.1002/slct.202501581","url":null,"abstract":"<p><b>Journal title</b>: ChemistrySelect</p><p><b>Submission DOI</b>: https://doi.org/10.1002/slct.202405649</p><p>Figure 4, Table 1, and the paragraph in Section 2.3 of our review were reused from ref. [13]. This reference was correctly cited twice in the paragraph of section 2.3 and in the figure caption, however, the permission and copyright statements were not included in the caption of the figure. We apologize to the authors of ref. [13] for this omission. Permissions for reproduction of all figures in our article have now been obtained. The corrected versions for Table 1 and Figure 4 are shown below.</p><p>Table 1. Different Crystal Arrangements of Nb Oxide. Reprinted with permission from ref. [13]. Copyright 2016, Elsevier.\u0000</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 18","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/slct.202501581","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143925763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Electrolytic Systems on Electrochemical Behavior of Dispersible Reduced Graphene Oxide Produced from Novel Reducing Agent","authors":"Kshama D. Lokhande,&nbsp;Mahesh P. Bondarde,&nbsp;Madhuri A. Bhakare,&nbsp;Kaustubh Kadam,&nbsp;Pratik S. Dhumal,&nbsp;Surajit Some","doi":"10.1002/slct.202501256","DOIUrl":"https://doi.org/10.1002/slct.202501256","url":null,"abstract":"<p>Graphene-based supercapacitors have been extensively explored to meet energy demands due to their excellent electrical conductivity and mechanical stability. This article gives important insights into solving the agglomeration and difficulty in dispersion issues by reducing and functionalizing graphene oxide (GO) using H-acid as a novel reducing agent. The sulfonic acid groups of H-acid help in the dispersion of as-prepared graphene (RGO/H-acid). The electrochemical performance of RGO/H-acid has been examined using two-electrode systems in different electrolytes such as 1 M KOH, H₂SO₄, and Na₂SO₄. Among these, the highest specific capacitance was 206.66 F g⁻¹ at 1 A g⁻¹ current density with excellent energy density of 23.24 Wh kg⁻¹ and power density of 1781.98 W kg⁻¹ in KOH electrolyte as compared to H₂SO₄ and Na₂SO₄. The EIS shows excellent supercapacitive performance and good charge transfer behavior of RGO/H-acid, and it shows lower series resistance of 0.72 Ω. The RGO/H-acid shows excellent cyclic stability up to 15000 charge-discharge cycles with 85.7% capacitance was retained, while only 15.3% performance was declined compared to initial specific capacitance. The present article highlighted the role and effect of acidic, basic, and neutral electrolytes toward the electrochemical performance of RGO/H-acid.</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 18","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143925874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}