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{"title":"Thermal Marangoni Convection in a Hemispherical Evaporating Liquid Droplet: Analytical Solution","authors":"P. V. Lebedev-Stepanov","doi":"10.1134/S1061933X26600740","DOIUrl":"10.1134/S1061933X26600740","url":null,"abstract":"<p>Quasi-stationary hydrodynamic flows have been studied in a small slowly evaporating hemispherical droplet with a pinned contact line on a flat horizontal substrate. Analytical solutions of the Stokes equations have been obtained and visualized for a capillary flow, which corresponds to the so-called “coffee-ring effect,” as well as for the Marangoni flow induced by a surface tension gradient associated with the cooling of the droplet surface due to the evaporation. The flow model corresponds to low Reynolds and Peclet numbers. The boundary conditions corresponding to the presence or absence of liquid slip at the substrate, which facilitate or hinder the Marangoni flow, have been analyzed. A hypothesis has been proposed that a critical Marangoni number corresponds to the system parameters that provide the separation of the flow from the substrate and the transition to the slip mode, in which the liquid velocity immediately at the substrate surface is nonzero. The obtained result can be used to study the flow structure and evaluate the flow rate in an evaporating microdroplet.</p>","PeriodicalId":521,"journal":{"name":"Colloid Journal","volume":"88 5","pages":"751 - 762"},"PeriodicalIF":1.6,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On the Electrostatic Interaction of Spheroidal Dielectric Particles in an Electrolyte Solution","authors":"S. I. Grashchenkov","doi":"10.1134/S1061933X26600661","DOIUrl":"10.1134/S1061933X26600661","url":null,"abstract":"<p>The electrostatic interaction of two identical charged dielectric spheroidal particles in a symmetric electrolyte solution has been considered. The finite element method has been used to calculate the repulsive forces between the particles by the Poisson–Boltzmann equation under the condition that their surface charge distribution is independent of the interparticle distance and there is no external electrostatic field. The charge distribution on the surface of each particle is assumed to coincide with that on an isolated individual particle at a given surface potential. It has been found that, depending on the Debye length and the distance between the particle surfaces, an increase in the longitudinal size of the particles upon the passage from oblate to prolate spheroids can either enhance or weaken the interaction force.</p>","PeriodicalId":521,"journal":{"name":"Colloid Journal","volume":"88 5","pages":"729 - 736"},"PeriodicalIF":1.6,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of a Chamber Temperature on the Tensile Strength and Impact Toughness of PA6 in FDM 3D Printing","authors":"Le Duong,&nbsp;Pham Thi Hong Nga,&nbsp;Ngo Vu Nguyen","doi":"10.1134/S0965545X26600377","DOIUrl":"10.1134/S0965545X26600377","url":null,"abstract":"<div><p>In fused filament fabrication/fused deposition modeling (FFF/FDM), the mechanical properties of Polyamide 6 (PA6) are strongly governed by thermal conditions during printing, particularly the build chamber temperature, which controls cooling rate, crystallinity, and interlayer bonding. This study evaluated three build chamber temperatures (30, 40, and 50°C) while keeping all other parameters constant to determine their effects on tensile strength, impact toughness, and microstructure. Five specimens per condition were tested for tensile and impact properties, and fracture surfaces were characterized by scanning electron microscopy (SEM). The results demonstrate a clear temperature dependence: increasing the chamber temperature from 30 to 50°C enhanced tensile strength from 21.32 to 24.61 MPa and impact toughness from 13.58 to 14.35 kJ/m², whereas 40°C yielded the lowest values of 16.09 MPa and 11.37 kJ/m². SEM observations suggested that specimens printed at 50°C exhibited improved filament fusion and fewer interlaminar voids, resulting in a more homogeneous and ductile fracture surface, whereas specimens printed at 40°C showed less uniform interlayer bonding and a more heterogeneous defect distribution. These observations are consistent with enhanced interlayer bonding under more favorable thermal conditions. The findings indicate that approximately 50°C is the optimal build chamber temperature within the investigated range, providing improved mechanical reliability of FFF/FDM-printed PA6 parts and a basis for optimizing the processing window for load-bearing applications.</p><div><figure><div><div><picture><img></picture></div></div></figure></div></div>","PeriodicalId":738,"journal":{"name":"Polymer Science, Series A","volume":"68 5","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Formation of Majorana Zero Modes in Chiral Carbon Nanotubes under the Influence of Geometric Factors","authors":"I. Erazo Velasco,&nbsp;D. A. Kuzmin","doi":"10.1134/S1063785026600535","DOIUrl":"10.1134/S1063785026600535","url":null,"abstract":"<p>In this paper, we investigate the occurrence of Majorana zero modes in carbon nanotubes in contact with a conventional superconductor and placed in a longitudinal magnetic field. The influence of nanotube geometry, determined by chirality indices <span>((n,m))</span>, on the conditions for the formation of the topological superconducting phase is considered. It is shown that chirality changes the electronic structure of the nanotube, the spin–orbit interaction and the effective chemical potential, which determine the conditions of the topological phase transition. To describe the system, an effective model based on the Bogolyubov–de Gennes Hamiltonian is constructed, which allows one to obtain a criterion for the occurrence of Majorana null modes. Based on the developed model, a method for selecting the most favorable geometries of carbon nanotubes is proposed. Numerical results show that certain chiralities minimize the effective chemical potential and facilitate the transition of the system to the topological phase. The obtained results show that the geometry of the carbon nanotube is an effective parameter for controlling the topological properties of the system and can serve as a criterion for choosing the chiralities that are most promising for the experimental implementation of Majorana zero modes.</p>","PeriodicalId":784,"journal":{"name":"Technical Physics Letters","volume":"52 9","pages":"507 - 520"},"PeriodicalIF":0.8,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On the Issue of Calculating Actuator Rod Stability When Regulating the Performance of a Piston Compressor","authors":"R. E. Kobyl’skiy","doi":"10.1134/S1063785026600596","DOIUrl":"10.1134/S1063785026600596","url":null,"abstract":"<p>An actuator rod (control device) is examined for the stability coefficient under a given load. It was found that commonly known calculation methods do not allow for the geometric features of the rod to be fully taken into account. To take into account the geometric features of the rod, a numerical experiment was carried out in the Compass APM FEM software environment. The numerical experiments conducted allow us to draw the following conclusions. When the ratio of the diameters of the inner hole to the diameter of the rod is 85%, as well as 71%, and when the ratio of the lengths of the inner hole to the length of the rod is from 100 to 31%, the presence of the inner hole greatly affects the safety factor, which varies in the range from 0.54 to 1.6. When the diameter ratio decreases, the length of the inner hole has virtually no effect on the safety factor, but in the range of length ratios from 100 to 50%, the safety factor is less than the recommended 1.8.</p>","PeriodicalId":784,"journal":{"name":"Technical Physics Letters","volume":"52 9","pages":"501 - 506"},"PeriodicalIF":0.8,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cinchonidine Ameliorates Traumatic Brain Injury-Related Neurobehavioral Deficits via the SRC/RAF1/NF-κB Pathway to Attenuate Mitochondrial Dysfunction","authors":"Han Tang,&nbsp;Jianchao Huang,&nbsp;Caixia Sun","doi":"10.1007/s11064-026-04925-1","DOIUrl":"10.1007/s11064-026-04925-1","url":null,"abstract":"<div><p>Cinchonidine (CD), a metabolite derived from gut microbiota, shows promise in protecting against traumatic brain injury (TBI), where mitochondrial dysfunction is a key driver of secondary damage. Using a mouse model of controlled cortical impact (CCI) and an in vitro primary neuron injury model, CD administration resulted in improved physiological status (weight recovery, stabilized heart rate) and behavioral outcomes (increased travel distance and speed) in TBI mice. Histological analysis showed reduced hippocampal neuronal damage, decreased pro-inflammatory cytokines (interleukin‑1β, interleukin‑6, and tumor necrosis factor‑α), and upregulated blood-brain barrier tight-junction proteins (Claudin-5, Occludin, zonula occludens‑1). Mitochondrial function was improved, evidenced by increased mitochondrial DNA copy number, elevated expression of translocase of outer mitochondrial membrane 20 and cytochrome c oxidase subunit IV, and restoration of mitochondrial membrane potential. In addition, CD attenuated TBI-induced changes in mitochondrial dynamics and biogenesis, restoring the phosphorylated dynamin-related protein 1 (p-DRP1)/DRP1 ratio and the expression of mitofusin 1/2 (MFN-1/2) and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), while reducing mitochondrial DRP1. Network pharmacology identified proto‑oncogene tyrosine‑protein kinase Src (SRC) as a key target, validated by stable binding in molecular docking and drug affinity responsive target stability assays. Furthermore, cellular thermal shift assays demonstrated a direct interaction between CD and SRC. CD treatment suppressed the activation of the SRC/RAF proto-oncogene serine/threonine-protein kinase (RAF1)/nuclear factor kappa B (NF-κB) signaling axis, as evidenced by reduced phosphorylation of SRC and p65, along with decreased expression of RAF1 and cleaved Caspase-3. Crucially, SRC knockdown mimicked CD’s protection, while SRC overexpression abolished its benefits. These findings suggest that CD ameliorates post-TBI mitochondrial dysfunction, neuroinflammation, and neuronal damage by inhibiting SRC kinase activity and its downstream RAF1/NF-κB signaling pathway. Thus, CD may represent a promising SRC-targeted neuroprotective strategy for TBI.</p></div>","PeriodicalId":719,"journal":{"name":"Neurochemical Research","volume":"51 6","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149219466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural, Mechanical and Morphological Characterizations of PMMA/PS Blends: Influence of Polystyrene on Poly(methyl methacrylate) Films","authors":"Karishma Tavar,&nbsp;Netram Kaurav,&nbsp;Jaiveer Singh,&nbsp;A. Sharma,&nbsp;J. Tripathi","doi":"10.1134/S0965545X26600390","DOIUrl":"10.1134/S0965545X26600390","url":null,"abstract":"<p>This study reports the structural, morphological, mechanical and dielectric behavior of solution-cast poly(methyl methacrylate) (PMMA) films containing trace fractions (0.5 and 1%) of polystyrene (PS). X-ray diffraction shows that all films are amorphous, exhibiting broad halos whose position reflects the average inter-chain spacing; PS incorporation shifts the halo slightly, indicating modestly looser chain packing rather than any crystalline change. FTIR and Raman spectroscopy reveal no new bands and only marginal shifts, confirming the absence of chemical bonding and consistent with the known immiscibility of PMMA and PS. Atomic force microscopy uncovers a composition-driven morphological transition: at 0.5% PS the surface develops a diffusion-limited dendritic network, which reorganizes into a phase-separated pore structure at 1%. Microhardness varies systematically with composition, and dielectric spectroscopy shows that ε′, ε″ and tanδ change measurably with PS content, which we attribute to interfacial polarization at the phase-separated domains. The results establish trace-PS addition as a simple route to tune the morphology and permittivity of PMMA films for dielectric-coating and flexible electronic applications.</p>","PeriodicalId":738,"journal":{"name":"Polymer Science, Series A","volume":"68 5","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanodispersion of Simple Liquids During Thermal Evaporation and Acoustic Cavitation","authors":"A. A. Sokurov,&nbsp;S. Sh. Rekhviashvili","doi":"10.1134/S1061933X26600764","DOIUrl":"10.1134/S1061933X26600764","url":null,"abstract":"<p>A theory has been developed for nanodispersion of a simple liquid under the conditions of thermal evaporation in a supersaturated medium and ultrasonic cavitation. The proposed theory takes into account the size dependence of surface tension. It has been shown that accounting for this dependence decreases the energy barrier of nucleation and the critical nucleus radius, while causing a significant asymmetry in the kinetics of the growth and evaporation of nanodroplets. The modified Rayleigh–Plesset equation has been used to show that the size dependence of the surface tension increases the capillary stiffness of a bubble, suppresses chaotic regimes, and preserves the scale-invariant (fractal) structure of cavitation oscillations. A new criterion has been obtained for the disappearance of the nucleation barrier. It has been shown that, under real conditions of ultrasonic cavitation, the supersaturation reaches values sufficiently high for the transition to the spinodal regime of spontaneous phase separation and the formation of nanodroplets (1–3 nm in size) without an activation delay.</p>","PeriodicalId":521,"journal":{"name":"Colloid Journal","volume":"88 5","pages":"799 - 807"},"PeriodicalIF":1.6,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Topologically Consistent Fuzzy Clustering in a Neurodynamic Model of the Traveling Salesman Problem","authors":"V. A. Sudakov","doi":"10.1134/S1064562426700110","DOIUrl":"10.1134/S1064562426700110","url":null,"abstract":"<p>A new neurodynamic model for joint optimization of the traveling salesman problem route and fuzzy cluster partitioning of a set of vertices is proposed. The model’s energy function includes three components: a Hopfield-Tank term encoding route feasibility constraints; a fuzzy means term ensuring geometric compactness of clusters; and a topological matching term penalizing for discontinuities in cluster membership between adjacent vertices along the route. An iterative minimization scheme is developed. The following convergence properties are proven: monotonic energy decrease and convergence of the energy sequence to a limit value. Computational experiments on a test example showed that the proposed model finds solutions that coincide with the global optimum, while the resulting clusters differ significantly from the results of the classical fuzzy c-means algorithm, reflecting the topology of the optimal route. The results of the study can be used for problems of delivery territory zoning, production operation planning, and condensation of large factor models.</p>","PeriodicalId":531,"journal":{"name":"Doklady Mathematics","volume":"113 3","pages":"75 - 83"},"PeriodicalIF":0.8,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thalamic PDK–PDHA1 Signaling is Associated with Opioid-Induced Loss-of-Righting-Reflex Sensitivity: Evidence from Phosphoproteomic Profiling and PDK Pathway Intervention","authors":"Man Li,&nbsp;Yijia Zhang,&nbsp;Bo Tan,&nbsp;Ruibin Su","doi":"10.1007/s11064-026-04922-4","DOIUrl":"10.1007/s11064-026-04922-4","url":null,"abstract":"<div><p>Opioids are widely used in clinical sedation and anesthesia, but the downstream phosphorylation events associated with opioid-induced reductions in arousal remain incompletely understood. Here, we investigated whether thalamic phosphoproteomic remodeling and the pyruvate dehydrogenase kinase (PDK)–pyruvate dehydrogenase E1 alpha subunit (PDHA1) pathway are associated with opioid-induced loss of righting reflex (LORR) in rats. Phosphoproteomic profiling of rat thalamic tissues after treatment with fentanyl, FENT-001 (a synthetic fentanyl analog), and other sedative and anesthetic agents revealed broad changes in thalamic phosphopeptide abundance.Differentially phosphorylated proteins were enriched in neuronal projections, synapses, cytoskeletal organization and synaptic transmission. PDHA1 was identified as a significantly differentially phosphorylated protein and was further examined by Western blotting. Fentanyl and 3-methylfentanyl altered phosphorylation at multiple PDHA1 sites. Pharmacological inhibition of PDKs with dichloroacetate reduced PDHA1 Ser293 phosphorylation in cultured cortical neurons and produced numerical increases in the estimated ED₅₀ values for fentanyl- and 3-methylfentanyl-induced LORR. These changes were consistent with a trend toward reduced LORR sensitivity. Conversely, CM-targeted overexpression of PDK2 or PDK4 shifted the fitted fentanyl-induced LORR dose–response curves to the left relative to the Vector control, with a larger numerical reduction in ED₅₀ following PDK2 overexpression.These findings suggest that opioid treatment remodels the thalamic phosphoproteome and that the PDK–PDHA1 phosphorylation pathway is functionally associated with opioid-induced LORR sensitivity.</p></div>","PeriodicalId":719,"journal":{"name":"Neurochemical Research","volume":"51 6","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149219463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}