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{"title":"α7-Nicotinic Acetylcholine Receptor Activation Modulates BV2 Microglial Plasticity via miR-21/TNF-α/NFκB in Oxygen–Glucose Deprivation/Reoxygenation","authors":"Mohammad Yusuf Hasan,&nbsp;Azim Haikal Md Roslan,&nbsp;Norazrina Azmi,&nbsp;Norlinah Mohamed Ibrahim,&nbsp;Alina Arulsamy,&nbsp;Vanessa Lin Lin Lee,&nbsp;Rosfaiizah Siran,&nbsp;Sharmili Vidyadaran,&nbsp;Eng Wee Chua,&nbsp;Mohd Kaisan Mahadi","doi":"10.1007/s12031-024-02300-9","DOIUrl":"10.1007/s12031-024-02300-9","url":null,"abstract":"<div><p>Elevated inflammatory reactions are a significant component in cerebral ischemia–reperfusion injury (CIRI). Activation of α7-Nicotinic Acetylcholine Receptor (α7nAChR) reduces stroke-induced inflammation in rats, but the anti-inflammatory pathway in microglia under CIRI condition remains unclear. This study employed qRT-PCR, protein assays, NanoString analysis, and bioinformatics to examine the effects of PNU282987 treatment (α7nAChR agonist) on BV2 microglial functional differentiation in oxygen–glucose deprivation/reoxygenation (OGDR) condition. OGDR significantly increased the gene expression of pro-inflammatory markers such as TNF-α, IL-6, and IL1β, while α7nAChR agonists reduced these markers. The anti-inflammatory gene marker IL-10 was upregulated by α7nAChR agonist treatment. Downstream pathway marker analysis showed that both gene and protein expression of NFκB was associated with anti-inflammatory effects. Blocking microRNA-21 with antagomir reversed the anti-inflammatory effects. NanoString analysis revealed that microRNA-21 inhibition significantly affected inflammation-related genes, including <i>AL1RAP</i>, <i>TLR9</i>, <i>FLT1</i>, <i>PTGIR</i>, <i>NFκB</i>, <i>TREM2</i>, <i>TNF</i>, <i>SMAD7</i>, <i>FOS</i>, <i>CCL5</i>, <i>IFIT1</i>, <i>CFB</i>, <i>CXCL10</i>, <i>IFI44</i>, <i>DDIT3</i>, <i>IRF7</i>, <i>OASL1</i>, <i>IL1A</i>, <i>IFIT2</i>, <i>C3</i>, <i>CD40</i>, <i>STAT2</i>, <i>IFIT3</i>, <i>IL1RN</i>, <i>OAS1A</i>, <i>CSF1</i>, <i>CCL4</i>, <i>CCL2</i>, <i>CCL3</i>, <i>BCL2L1</i>, and <i>ITGB2</i>. Enrichment analysis of upregulated genes identified Gene Ontology Biological Processes related to cytokine responses and TNF-associated pathways. This study highlights α7nAChR activation as a key regulator of anti-inflammatory responses in BV2 microglia under OGDR conditions, with micro-RNA21 identified as a crucial mediator of receptor-driven neuroprotection via the TNF-α/NF<i>κ</i>B signalling pathway.</p></div>","PeriodicalId":652,"journal":{"name":"Journal of Molecular Neuroscience","volume":"75 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142880486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of pillar shapes on the cell isolation in contactless DEP microfluidic devices","authors":"Mohsen Mashhadi Keshtiban,&nbsp;Peyman Torky Harchegani,&nbsp;Mahdi Moghimi Zand,&nbsp;Zahra Azizi","doi":"10.1007/s10404-024-02772-6","DOIUrl":"10.1007/s10404-024-02772-6","url":null,"abstract":"<div><p>Contactless dielectrophoresis is an effective method for trapping and manipulating cells in microfluidic devices. However, the efficiency of these devices decreases at higher flow rates. To address the limitation of previous studies, a new pillar shape is introduced and numerically simulated to isolate THP-1 cells and efficiently separate them from red blood cells (RBCs). A comparison is made in two microchannels with the novel pillar shape of two perpendicular ellipses and the circular pillar shape as the reference case. Simulation results demonstrate that the use of two perpendicular ellipticals pillar shape improves the electric characteristics of the device, showing 92.7% higher <span>(nabla {E}_{rms}^{2})</span> compared to the channel with circular pillars. The working frequency is selected based on the CM factor to isolate THP-1 cells without affecting RBCs. Additionally, the new pillar configuration exhibited 116% higher cell trap efficiency compared to the chip with circular pillars.</p></div>","PeriodicalId":706,"journal":{"name":"Microfluidics and Nanofluidics","volume":"29 2","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142880541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tackling Biofilm Resistance of Gram-Positive and Gram-Negative Bacteria Against Levofloxacin via Nanotechnology and Essential Oils","authors":"Sarhan Omnia Mohamed","doi":"10.1007/s12247-024-09891-1","DOIUrl":"10.1007/s12247-024-09891-1","url":null,"abstract":"<div><h3>Introduction</h3><p>The generation of biofilms by bacteria has become a major factor in the rise of antibiotic resistance. Lipid nano-capsules (LNCs) have recently emerged as an innovative platform for drug delivery, due to their unique properties and ability to carry a wide array of therapeutic chemical compounds.</p><h3>Objectives</h3><p>The objective of this research was to create, optimize, and evaluate the antibiofilm efficacy of a peppermint oil emulsion (o/w) containing levofloxacin against resistant bacteria via biofilm formation.</p><h3>Methods</h3><p>Essential oils, particularly peppermint oil known for its antifungal properties, were employed instead of traditional medium chain triglycerides to formulate lipid nanocarriers, utilizing alternating surfactant types (Solutol HS 15 and Cremophor EL) and differing oil to surfactant ratios (2:1 and 1:1). The LFX-LNCs formula, with a 2:1 oil to surfactant ratio, was selected for further investigation due to its physical properties, including particle size, zeta potential, transmission electron microscopy, and polydispersity index. The antibacterial efficiency of LFX-LNCs was evaluated, revealing their ability to eradicate established biofilms of Gram-negative pathogens, including Escherichia coli (E. coli) and Pseudomonas aeruginosa (P. aeruginosa), as well as Gram-positive strains such as Staphylococcus aureus (S. aureus).</p><h3>Results</h3><p>The mean particle size of LFX-LNCs varied from 30.86 ± 0.54 nm to 68.36 ± 0.56 nm, demonstrating a narrow size distribution, a negative zeta potential (-1.56 ± 0.24 to -20.2 ± 2.15 mV), and a polydispersity index (PDI) ranging from 0.062 ± 0.006 to 0.26 ± 0.002. Lipid nanocapsules generally exhibit a spherical morphology within the nanometric size range when analyzed by transmission electron microscopy (TEM). The antimicrobial activity assessment revealed that EL 2:1 exhibited the most significant antimicrobial efficacy, characterized by a reduced particle size and an inhibition zone measuring up to (2.43 ± 0.24 cm), demonstrating promising results against several pathogenic strains, including <i>P. aeruginosa</i>, <i>S. aureus</i>, and <i>E. coli</i>.</p><h3>Conclusion</h3><p>This study illustrates the efficacy of LFX-LNCs in the treatment of non-healing wounds infected with biofilm-forming bacteria.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":656,"journal":{"name":"Journal of Pharmaceutical Innovation","volume":"20 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s12247-024-09891-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142880539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geochemical and magnetic properties in fluvial and lacustrine systems as environmental quality proxies in the Atacama Desert","authors":"Adriana Aránguiz-Acuña,&nbsp;Héctor Pizarro,&nbsp;Abraham Flores-Varas,&nbsp;Joseline Tapia,&nbsp;Josefina Herrera,&nbsp;Santiago Maza","doi":"10.1007/s12665-024-12023-0","DOIUrl":"10.1007/s12665-024-12023-0","url":null,"abstract":"<div><p>Rivers play a crucial role in landscape evolution and human development, especially in arid zones, where hydrological resources are scarce and in high demand. The Atacama Desert is one of the world’s oldest and driest non-polar deserts, and aquatic systems therein have been historically subjected to anthropogenic pressure mainly associated with natural resource exploitation, such as water consumption for industrial mining activities. The mining industry has experienced a systematic development since the early 20th century, making Chile one of the main worldwide copper producers. This study analyzed sediments from two Atacama Desert rivers, the Loa and Salado Rivers (Antofagasta Region, Northern Chile). Sedimentary short-cores were obtained from sampled locations at varying distances from the confluence of the rivers. The characterization of chemical components, grain size, mineralogy, and magnetic properties of the rivers’ sediments was assessed in surface and subsurface samples to determine their respective signatures in the Inka-Coya Lake near the rivers’ confluence. The magnetic mineralogy present in the sediments of both rivers is composed of detrital magnetite and maghemite interspersed with those of authigenic origin. However, the downstream Loa River concentrated more authigenic minerals than the Salado and increased the abundance of silt-sized particles. The grain size of the Loa’s channel bed suggests low stream competency and high formation of depositional habitats. The magnetic signal and mineralogical composition of sediments from the lake are dominated by detrital pyrite, magnetite, and authigenic greigite. In contrast, the river’s sediments were dominated by magnetite and maghemite of detrital origin intercalated with those of authigenic origin. The granulometry, mineralogy, and rock magnetic properties of Inka-Coya Lake sediments indicate recent detrital input alternating with authigenic mineral-rich layers, mainly reflecting shifts in hydrological regimes. The highest concentrations of copper were observed in the upper, more recent sediment layers. Future scenarios of risky climatic conditions associated with increasing global metal demands could modify the availability of potentially toxic elements and transport capability in fluvial sediments, increasing the threats to water resource conservation in the world’s most arid desert.</p></div>","PeriodicalId":542,"journal":{"name":"Environmental Earth Sciences","volume":"84 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s12665-024-12023-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plasmonic nanostructures for color vision deficiency (CVD) management","authors":"N. Roostaei,&nbsp;S. M. Hamidi","doi":"10.1140/epjp/s13360-024-05921-6","DOIUrl":"10.1140/epjp/s13360-024-05921-6","url":null,"abstract":"<div><p>Color blindness, also known as color vision deficiency (CVD), is a prevalent ocular disorder that hinders distinguishing different colors, a challenge experienced by a considerable portion of the global population (8−10% of males and 0.4−0.5% of females). CVD patients are frequently restricted from crucial professions such as military or police, and cannot recognize colors in public places or media like watching TV. Despite ongoing efforts, there is no definitive cure for color blindness; however, various color filter-based devices such as tinted glasses and contact lenses have been introduced to assist CVD people. Recently, plasmonic nanostructures have attracted significant attention for CVD management by replacing chemical dyes due to their outstanding properties and the adjustability of plasmonic resonances. This study reviews the different wearables utilized in CVD management, such as eyeglasses and contact lenses, with a special emphasis on the innovative plasmonic eye wearables that have emerged in recent advances. The capability to modify the plasmonic properties by manipulating their morphology provides novel perspectives for CVD management and smart ophthalmic wearables.</p></div>","PeriodicalId":792,"journal":{"name":"The European Physical Journal Plus","volume":"139 12","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relativistic Covariance of Scattering","authors":"Norbert Dragon","doi":"10.1007/s10773-024-05861-y","DOIUrl":"10.1007/s10773-024-05861-y","url":null,"abstract":"<div><p>Avoiding the assumption that relativistic scattering be describable by interacting fields we find in the Schrödinger picture relativistic scattering closely analogue to the non-relativistic case. On the space of scattering states the invariant mass operator <span>(M')</span> of the interacting time evolution has to be unitarily equivalent to the invariant mass <span>(M= sqrt{P^2})</span> where <i>P</i>, acting on many-particle states, is the sum of the one-particle four-momenta. For an observer at rest <span>(P^0)</span> generates the free time evolution. Poincaré symmetry requires the interacting Hamiltonian <span>(H')</span> to Lorentz transform as 0-component of a four-vector and to commute with the four-velocity <span>(U= P / M )</span> but not with <i>P</i>, else there is no scattering. Even though <span>(H')</span> does not commute with <i>P</i>, the scattering matrix does. The four-velocity <i>U</i> generates translations of states as they are seen by shifted observers. Superpositions of nearly mass degenerate particles such as a <span>(K_{text {long}})</span> are seen by an inversely shifted observer as a shifted <span>(K_{text {long}})</span> with an unchanged relative phase. In contrast, the four-momentum <i>P</i> generates oscillated superpositions e.g. a shifted <span>(K_{text {short}})</span> with a changed relative phase. The probability of scattering of massive particles is shown to be approximately proportional to the spacetime overlap of their position wave functions. This is basic to macroscopic locality and justifies to represent the machinery of actual scattering experiments by the vacuum. In suitable variables the relativistic Hamiltonian of many-particle states is not the sum of a Hamiltonian for the motion of the center and a commuting Hamiltonian for the relative motion but factorizes as their product. They act on different variables of the wave functions.</p></div>","PeriodicalId":597,"journal":{"name":"International Journal of Theoretical Physics","volume":"63 12","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10773-024-05861-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laboratory appraisal of geomechanical and mineralogical factors controlling landslide potential of soil-shales matrix","authors":"Jahanzaib Israr,&nbsp;Gang Zhang,&nbsp;Mohsin Waheed Qureshi","doi":"10.1007/s10064-024-04043-8","DOIUrl":"10.1007/s10064-024-04043-8","url":null,"abstract":"<div><p>This study reports on results from a series of geohydraulic, geomechanical, and mineralogical tests conducted on 12 different landslide samples consisting of broadly graded and potential internally unstable soils. The test samples contained almost 50% coarser or rock (cobbles-gravels) fraction and 50% finer or soil (sand-silt) fraction. The current test results characterized the landslide samples as highly erodible, while their regraded rock and soil fractions showed non-erodibility with good strength and drainage characteristics. For instance, the landslide samples suffer from a classical suffusion failure at critical hydraulic gradients below 0.38 with up to 20% erosion, while their regraded sand-silt fraction remains internally stable even at <span>({i}_{cr})</span> up to 0.80 with less than 4% erosion. Subsequently, the results of pinhole erosion testing revealed that the silt component exhibited a high dispersion index D1. Similarly, the coarser fraction showed more than 95% slake durability, while the point load testing both parallel and perpendicular to the planes of weaknesses yielded a shale rating of nearly 8 reflecting high durability against abrasion. Results of both XRD and SEM analyses revealed that the intact landslide samples contained up to 50% Quartz and 42% Calcites with traces of Halite, Bornite, Silicon, and Fluorite minerals. However, the Calcite content of the displaced samples reduced to as low as 11% with subtle variations in other minerals that would result in lower inter-particle cementation and enhanced erodibility, thus making the entire soil matrix a highly erodible material. In essence, the Calcite provides sufficient cementation to the finer fraction that enables the particles to stick together and stay intact inside the constriction network of coarser fraction to ensure stability. However, the loss of Calcite and hence the cementation would trigger the internal erosion of soil fraction to eventually develop a landslide on steeper slopes.</p></div>","PeriodicalId":500,"journal":{"name":"Bulletin of Engineering Geology and the Environment","volume":"84 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An aptamer sensor based on AgNPs@MOF for surface-enhanced Raman spectroscopy detection of sulfadimethoxine in food","authors":"Zhanye Yang,&nbsp;Nan Zhang,&nbsp;Haiyang Lv,&nbsp;Xinge Ju,&nbsp;Yanhua Chen,&nbsp;Ziwei Zhang,&nbsp;Yuan Tian,&nbsp;Bing Zhao","doi":"10.1007/s00604-024-06897-x","DOIUrl":"10.1007/s00604-024-06897-x","url":null,"abstract":"<div><p>A highly sensitive aptamer sensor (aptasensor) is proposed based on metal–organic frameworks-silver nanoparticles (AgNPs@MOF) to detect sulfadimethoxine (SDM) by surface-enhanced Raman spectroscopy (SERS). AgNPs@MOF with SERS activity was successfully fabricated by synthesizing AgNPs in situ on the surface of MIL-101(Fe), and SDM aptamer and Raman reporter 4-aminophenthiophenol (4-ATP) were selected as specific recognition elements and signal probes, respectively. When SDM was absent, the SDM aptamers were effectively adsorbed on the surface of AgNPs@MOF, thus keeping AgNPs@MOF in a dispersed state, resulting in a weakened SERS signal of 4-ATP. In the presence of SDM, the combination of SDM and aptamer formed a rigid hairpin SDM-aptamer complex, which bound less to AgNPs@MOF. Therefore, fewer aptamers were adsorbed on AgNPs@MOF, which exposed more hot spots, resulting in an enhanced SERS signal of 4-ATP. The aptasensor had good selectivity and sensitivity towards SDM and a good linear relationship between SERS intensity and SDM concentration in the range 6.00–150.00 ng/mL, with the limit of detection as low as 2.73 ng/mL. Further application to honey and chicken samples spiked with SDM resulted in satisfactory recoveries, and the aptasensor showed good stability and reproducibility in real samples. The aptasensor based on AgNPs@MOF was proposed for the first time to detect trace SDM by SERS, which provided a favorable way to develop various sensing platforms for antibiotic detection in food safety.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 1","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142880495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Generalized uncertainty principle corrections in Rastall–Rainbow Casimir wormholes","authors":"Emmanuele Battista,&nbsp;Salvatore Capozziello,&nbsp;Abdelghani Errehymy","doi":"10.1140/epjc/s10052-024-13656-y","DOIUrl":"10.1140/epjc/s10052-024-13656-y","url":null,"abstract":"<div><p>We explore wormhole solutions sourced by Casimir energy density involving generalized uncertainty principle corrections within the framework of Rastall–Rainbow gravity. The questions of traversability and stability, as well as the presence of exotic matter, are carefully investigated. In particular, the stability issue is addressed via an approach that has not been previously employed in the context of wormholes. This method, which represents an improved version of the so-called Herrera cracking technique, has the potential to yield novel insights in the field of wormhole geometries.</p></div>","PeriodicalId":788,"journal":{"name":"The European Physical Journal C","volume":"84 12","pages":""},"PeriodicalIF":4.2,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1140/epjc/s10052-024-13656-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142880521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-party quantum Byzantine consensus based on full quantum one-way function","authors":"Tao Shang,&nbsp;Yao Tang,&nbsp;Yuanjing Zhang,&nbsp;Kun Zhang,&nbsp;Yazhuo Jiang","doi":"10.1007/s11128-024-04621-5","DOIUrl":"10.1007/s11128-024-04621-5","url":null,"abstract":"<div><p>In distributed systems, Byzantine consensus serves as a practical approach to addressing the Byzantine general problem. Previous research has exploited quantum resources to develop quantum detectable Byzantine consensus protocols, aiming to surpass the 1/3 fault tolerance bound. However, these consensus protocols are designed under the assumption of secure channel. They ignored malicious participants’ attacks on the communication process. In this paper, we introduce a new quantum protocol for quantum Byzantine consensus utilizing the full quantum one-way function, which is the foundation for generating verification state in list distribution phase and secure message in agreement phase. By relying on the quantum circuit of the full quantum one-way function, the honest participants are able to reach consensus, while the malicious participants are effectively detected. In order to enhance the scalability of the proposed quantum Byzantine consensus protocol, we categorize the participants into three-member groups when the number of participants is <span>(n&gt;3)</span>. Meanwhile, the election of commander is introduced in agreement phase. In the proposed multi-party quantum Byzantine consensus protocol, the full quantum one-way function verifies the honesty of the participants in both list distribution phase and agreement phase. Security analysis demonstrates that the proposed multi-party quantum Byzantine consensus protocol is secure against quantum attacks and the dishonest behaviors of participants.</p></div>","PeriodicalId":746,"journal":{"name":"Quantum Information Processing","volume":"24 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142880519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}