Elsevier最新文献

{"title":"Corrigendum to 'Recent advances in nanomaterial-based electrochemical aptasensors for detecting aquatic toxins in shellfish and freshwater. A review' [Talanta 297 (2026) 128589].","authors":"Girma Selale Geleta, Douglas P M Saraiva, Leonardo M A Ribeiro, Jian F S Pereira, Mauro Bertotti","doi":"10.1016/j.talanta.2025.128654","DOIUrl":"10.1016/j.talanta.2025.128654","url":null,"abstract":"","PeriodicalId":435,"journal":{"name":"Talanta","volume":" ","pages":"128654"},"PeriodicalIF":6.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Volumetric absorptive microsampling and conductive vial electromembrane extraction for the analysis of pharmaceuticals in whole blood.","authors":"Adam Reguli, Samira Dowlatshah, Frederik André Hansen, Petra Štěrbová-Kovaříková, Stig Pedersen-Bjergaard","doi":"10.1016/j.talanta.2025.128523","DOIUrl":"10.1016/j.talanta.2025.128523","url":null,"abstract":"<p><p>Volumetric absorptive microsampling (VAMS) enables accurate collection of low blood volumes, independent of hematocrit. Electromembrane extraction (EME) is a sustainable sample clean-up technique; however, its wider applicability to extract analytes directly from VAMS tips remains unexplored. This study aimed to evaluate applicability of the first commercially available conductive vial EME device (with 2-nitrophenyl octyl ether as liquid membrane) for isolating 41 basic pharmaceuticals (log P 2-6) from 10 μL of blood on VAMS tips. The following extraction parameters were optimized: donor solution composition and volume, conductive vials size, applied voltage, extraction time and agitation speed. It was found that: 1/large conductive vials (600 μL) and 300 μL of donor solution provide higher process efficiency and reproducibility compared to smaller vials (200 μL) or larger donor solution volumes; 2/methanol in donor solution improve reproducibility and 3/sonication of VAMS tips in donor solution within a conductive vial prior to extraction enhances process efficiency. The EME protocol, followed by UHPLC-MS/MS analysis, was evaluated for process efficiency, linearity (1-1000 ng/mL), precision, and accuracy. Eleven analytes met most of the predefined acceptance criteria: process efficiencies 34.9-65.8 %, linearity (R²) 0.9933-0.9995, accuracy 85.9-111.1 % and precision 1.4-13.3 % RSD. The extraction was not impacted by hematocrit variation. EME demonstrated superior reproducibility and reduced matrix effects when compared to conventional VAMS tips treatment. This study confirms the reliability of a commercial conductive vial EME device for isolating basic pharmaceuticals from whole blood on VAMS tips, highlighting its potential for routine bioanalytical applications.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"296 ","pages":"128523"},"PeriodicalIF":6.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144525853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An integrated ratiometric fluorescent probe based on the MOF-on-MOF heterostructure for sensitive detection of nerve agent simulant.","authors":"Qing Peng, Chenxin Qiu, Pengcheng Huang, Fang-Ying Wu","doi":"10.1016/j.talanta.2025.128528","DOIUrl":"10.1016/j.talanta.2025.128528","url":null,"abstract":"<p><p>As highly toxic organophosphates, nerve agents can lead to the dysfunction of the nervous system, so the detection of nerve agents has become an important topic. Herein, a MOF-on-MOF heterostructure, Eu-BTC@UiO-66-NH₂, was simply prepared via the interfacial growth approach to construct an integrated ratiometric fluorescent probe for the detection of nerve agent simulant diethyl chlorophosphate (DCP) both in the liquid and gas phases. In this detection system, the binding of DCP to the Zr-O clusters in UiO-66-NH₂ blocked a ligand-metal charge transfer (LMCT) process and restored the blue fluorescence of ligand (BDC-NH₂). On the other hand, the affinity of DCP with Eu³⁺ in Eu-BTC hindered a ligand-metal energy transfer (LMET) process, and destroyed the antenna effect, thereby resulting in the weakening of the red fluorescence of Eu³⁺. Using the dual-emission response, this probe enabled ratiometric fluorescence detection of DCP with high accuracy and visualization capability. In addition, the probe was introduced into portable sodium alginate hydrogel to realize direct and sensitive detection of DCP vapor. This work is thus expected to hold great potential for on-site monitoring of nerve agents in a simple yet efficient way.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"296 ","pages":"128528"},"PeriodicalIF":6.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144525850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The total antioxidant capacity of fruit was determined by TAMzyme pseudo-peroxidase activity colorimetry.","authors":"Xinli Guo, Shuangshuang Yan, Nishan Jin, Wenbin Zhong, Dongying An, Murui Ying, Yutian Zhou, Yudong Wu, Xin Li, Yang Zhang","doi":"10.1016/j.talanta.2025.128517","DOIUrl":"10.1016/j.talanta.2025.128517","url":null,"abstract":"<p><p>The total antioxidant capacity (TAC) of fruits is a key indicator for measuring their quality and nutritional value. Traditional detection methods are time-consuming and cumbersome, failing to meet the requirements for rapid detection. In this study, a novel triple metal organic framework nanozyme (TAMzyme) with superior peroxidase-like (POD-like) activity is constructed for colorimetric detection of TAC. Owing to the Fe, Co, Ni doping and unique long spindle structures, the TAMzyme possesses more surface active oxygen species, negative surface charges and rapid mass transport, thus resulting in higher catalytic activity and reaction rate. Thanks to the remarkable peroxidase-like activity, the antioxidant capacity of ascorbic acid (AA), cysteine (Cys), glutathione (Glu), and gallic acid (GA) was evaluated with a detection limit between 0.54 and 1.58 μM. Antioxidant capacity was quantified in μM Trolox Equivalent (TE), with Trolox as the standard reference compound. The sensor accurately determined the TAC in kiwi fruit (194.97 ± 2.73 μM TE) and oranges (205.10 ± 3.85 μM TE), aligning with results from a standardized ABTS kit. This study presents a rapid, cost-effective, and straightforward method for quantifying TAC in complex food matrices.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"296 ","pages":"128517"},"PeriodicalIF":6.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144558729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fast and portable single-sensor electronic nose for accurate quality assessment of extra virgin olive oil using a temperature-modulated generic gas sensor.","authors":"Amir Amini, Hossein Gholami Anjileh, Hooman Amirfaridi","doi":"10.1016/j.talanta.2025.128490","DOIUrl":"10.1016/j.talanta.2025.128490","url":null,"abstract":"<p><p>Preserving the quality of extra virgin olive oil (EVOO), regarded as the best quality of olive oil categories in compliance with the International Olive Council (IOC), is mainly impeded by blending it with inferior or alternative edible oils. A portable, accurate, and rapid electronic nose was developed to assess the purity of EVOO blended with small amounts of virgin olive oil (VOO) in five different relative proportions. A thermal shock-induced (TSI) SnO₂ gas sensor was employed, obviating the necessity for a sensor array and eliminating multi-dimensional drift. The discriminative response time was optimized to 3.2 s, with consistent repeatability over three-month experiments. After preprocessing, feature selection was performed, followed by a combination of principal component analysis (PCA) and linear discriminant analysis (LDA), which effectively segregated olive oil clusters in 3D feature space. A k-NN classifier utilizing Euclidean distance achieved an exceptional 98 % accuracy for k = 7 in identifying the five binary proportions of EVOO and VOO, proving the capability of the designed e-nose to detect the quantity of complex odor mixtures. The setup's accuracy was subsequently assessed using the 25 validation data, yielding a precision of 92 %. The successful classification rate of the designed e-nose was attributed to the lower oxidative stability of pure VOO compared to pure EVOO, which led to the faster formation and decomposition of volatile organic compounds (VOCs) of VOO on the sensing pellet of the TSI gas sensor. This innovative e-nose shows great promise for industrial applications in recognizing the mixtures of complex odors.</p>","PeriodicalId":435,"journal":{"name":"Talanta","volume":"296 ","pages":"128490"},"PeriodicalIF":6.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144525852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coral reef-inspired hierarchical channel electrolyte: LATP framework-ZrO₂ triggering activation of amorphous fast-ion channels in PVDF-HFP.","authors":"Zihao Dang, Ao Li, Lin Wu, Tao Huang, Baoguo Zhang, Chenglin Wei, Yongkang Xu, Pinghui Xu, Dan Xiong, Rongsheng Chen, Ya Hu","doi":"10.1016/j.jcis.2025.138607","DOIUrl":"10.1016/j.jcis.2025.138607","url":null,"abstract":"<p><p>To cope with the demand for high-safe lithium-ion batteries, this study developed a new PVDF-HFP/LiTFSI/LATP/ZrO₂ (PHLZ) composite solid electrolyte with coral reef-type hierarchical channel structure. This electrolyte integrates the advantages of the NASICON fast ion conductor Li₁.₃Al₀.₃Ti₁.₇(PO₄)₃ (LATP) framework and the multifunctional inducer ZrO₂ through a dual-filler synergistic strategy. LATP large particles construct a continuous three-dimensional lithium ion rapid transmission main channel and promote LiTFSI dissociation through the surface Lewis acid site. ZrO₂ nanoparticles effectively passivate the LATP surface to inhibit reduction and improve their dispersion, and form hydrogen bonds with the -CF₂-group of PVDF-HFP through the surface hydroxyl group, trigger activation of the fast ion channel in the amorphous region of the polymer and inhibit crystallization. The PHLZ-2 electrolyte with an optimized ratio (LATP:ZrO₂ = 2:1) exhibits excellent comprehensive performance, with ion conductivity up to 1.76 × 10^-3 S cm^-1 at 60 °C, lithium ion migration number up to 0.76, wide electrochemical window (>4.74 V vs. Li⁺/Li), significantly improved thermal stability and flame retardant (3 s self-extinguishing), and excellent lithium deposition/peel stability. When applied to Fe₃O₄/phosphorus doped graphene oxide (FPG) anode system, the FPG//PHLZ-2//Li half-cell showed high rate performance (1101.65 mAh g^-1 at 3 A/g) and long cycle life (1225.19 mAh g^-1 after 300 times at 1.10 mA cm^-2); the assembled FPG//PHLZ-2//LFP full battery also showed high capacity and excellent cycle stability. This research provides new ideas for designing high-performance and safe composite solid electrolytes.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"700 Pt 3","pages":"138607"},"PeriodicalIF":9.7,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recycling of active pharmaceutical ingredients Metformin hydrochloride and Losartan potassium from expired medications and crystal structure of a new Losartan polymorphic form.","authors":"Laura Galindo-Leon, Juan D Galofre-Benitez, Julián Corredor-Gamba, Deissy N Jaramillo, Johan D Lozano, Mario A Macías, Elizabeth Jiménez-Díaz","doi":"10.1016/j.jpba.2025.117090","DOIUrl":"10.1016/j.jpba.2025.117090","url":null,"abstract":"<p><p>The disposal of expired pharmaceutical tablets, particularly those from household sources, is a growing environmental concern due to the accumulation of pharmaceutical contaminants in water ecosystems. Despite FDA recommendations to discard expired medications, studies have shown that many of these pills retain up to 90 % of their original potency long after their expiration date. This opens up the possibility for recycling and reusing the Active Pharmaceutical Ingredients (APIs) contained in these expired pills. This study presents a simple yet effective extraction protocol for recovering APIs from expired tablets of Metformin hydrochloride and Losartan potassium. The method achieved recovery yields of 88 % for Losartan and 37 % for Metformin. Structural characterization via NMR, HPLC, IR, HRMS, and both powder, and single-crystal X-ray diffraction confirmed the integrity and high purity of the recovered APIs compared to chemical standards. Biological assays carried out in L929 cell line revealed that the extracted APIs retained comparable activity to their chemical-standard counterparts, suggesting their potential for reuse in biochemical assays. During the recrystallization process by using PDRX, a new polymorphic form of Losartan potassium was discovered and named \"Form M\". In addition, a twelve-month stability study showed no degradation for either API at storage conditions. These results suggest that expired APIs are chemically and biologically viable for repurposing, as synthetic precursors in chemical research and in biological assays. The protocol is scalable, adaptable to pharmaceutical companies, and applicable in both industrial and research settings, offering a sustainable solution to pharmaceutical waste. By recovering APIs for educational and industrial use, this approach promotes environmental stewardship and resource efficiency in pharmaceutical science.</p>","PeriodicalId":16685,"journal":{"name":"Journal of pharmaceutical and biomedical analysis","volume":"266 ","pages":"117090"},"PeriodicalIF":3.1,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144816971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cauliflower-like manganese oxide@carbon cathode with structural and interfacial dual optimization for ultrastable zinc-ion batteries.","authors":"Yu Huang, Jianjiang Mao, Guoxiu Wang, Yanzhen He, Fei Cheng","doi":"10.1016/j.jcis.2025.138539","DOIUrl":"10.1016/j.jcis.2025.138539","url":null,"abstract":"<p><p>Manganese-based oxide cathode materials have attracted significant attention in aqueous zinc-ion batteries (AZIBs) due to their high energy density and operating voltage, but their practical applications are limited by the structural instability caused by manganese dissolution and sluggish kinetics resulting from poor electrical conductivity. Herein, a cauliflower-like MnO/carbon composite (NMOC) with hierarchical porous architecture is designed and fabricated through NaCl phase-dynamic regulation strategy by using a cost-effective manganese tartrate as the precursor. The dynamic NaCl template not only directs the self-assembly of MnO nanoparticles into three-dimensional interconnected porous frameworks but also facilitates the in-situ formation of an ultrathin (∼2 nm) carbon coating layer. As a high-performance cathode material for AZIBs, this unique structural configuration of NMOC establishes abundant Zn²⁺/H⁺ diffusion pathways, exposes high-density active sites, and significantly enhances reaction kinetics. Meanwhile, the strengthened Mn-O-C interfacial coupling and carbon confinement effect collectively suppress Mn dissolution, mitigate volume variation, and promote charge transfer dynamics. As a result, the NMOC cathode delivers an exceptional capacity of 561 mAh g^-1 at 0.2 A g^-1 and demonstrates ultra-stable cycling performance with 190 mAh g^-1 retained after 2000 cycles at 2 A g^-1 and nearly 100 % capacity retention (127 mAh g^-1) after 2500 cycles at 4 A g^-1. Furthermore, the constructed flexible cells demonstrated excellent mechanical and electrochemical properties. This work offers new insights into the interfacial modulation and kinetic optimization of manganese-based oxides in next-generation energy storage systems.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"700 Pt 3","pages":"138539"},"PeriodicalIF":9.7,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144797781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaporation-coded fluorescent gradients in supramolecular gels displaying aggregation-induced emission: A dynamic route to encryption and anti-counterfeiting.","authors":"Binbin Zhang, Qingyang Zhang, Xiheng Yuan, Zhenyu Lu, Yijun Zhang, Yujie Wang, Guangyue Bai","doi":"10.1016/j.jcis.2025.138643","DOIUrl":"10.1016/j.jcis.2025.138643","url":null,"abstract":"<p><p>Supramolecular gels have been widely explored as functional materials; however, their performance often degrades upon solvent evaporation. Although many strategies seek to mitigate this instability, few have leveraged solvent loss as a functional driver. Herein, we present an aggregation-induced emission (AIE)-active supramolecular gel that exploits solvent evaporation for dynamic information encryption and anti-counterfeiting. In this multicomponent co-assembly, a phenylalanine-functionalized 1,3,5-benzenetricarboxamide derivative (C₃-Phe), sodium hyaluronate (HA), and Al³⁺ ions together immobilize the AIE luminogen 4,4'-(1,2-diphenylethene-1,2-diyl)dibenzoic acid (TPE-CA), enhancing its quantum yield from 1.91 % to 62.43 %. The introduction of fluorescent dyes 4,7-di(2-thienyl)-2,1,3-benzothiadiazole (DBT) and rhodamine B (RhB) further establishes a cascade Förster resonance energy transfer (FRET) platform to enable tunable multicolor emission. The controlled evaporation of water drives time-dependent fluorescence chromatic shifts and quenching, which are fully reversible upon water replenishment. This evaporation-coded reversible fluorescence behavior underpins a 4D encryption and anti-counterfeiting platform that features multistage authentication and self-erasing information, thereby offering a new paradigm for adaptive smart materials.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"700 Pt 3","pages":"138643"},"PeriodicalIF":9.7,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144803155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oxygen vacancy-rich CoSn(OH)₆/FeS₂ heterostructure-based microneedles for combinatorial cancer therapy via activation of ferroptosis and apoptosis.","authors":"Qing Zhang, Jian Jiang, Tingting Hu, Mengshu Xu, Xueyan Zhang, Chunyu Yang, Zhuoran Yang, Wei Guo","doi":"10.1016/j.jcis.2025.138558","DOIUrl":"10.1016/j.jcis.2025.138558","url":null,"abstract":"<p><p>Resistance to apoptosis-based cancer therapies severely limits treatment efficacy. Ferroptosis, a distinct form of regulated cell death driven by lipid peroxidation, offers a promising alternative to overcome such resistance. Herein, we developed an innovative microneedle patch system (CFA-MN) incorporating an oxygen vacancy-rich hollow CoSn(OH)₆/FeS₂ (CF) heterostructure, combined with the alkyl radical initiator 1,2-bis(2-(4,5-dihydro-1Himidazol-2-yl)propan-2-yl) diazene dihydrochloride, to achieve cooperative apoptosis-ferroptosis cancer therapy. The CF heterostructure, synthesized via alkaline etching and solvothermal methods, exhibited abundant oxygen vacancy, enhancing reactive oxygen species generation under 808 nm laser irradiation. In the tumor microenvironment, FeS₂ facilitated controlled H₂S release, inhibiting epithelial-mesenchymal transition and promoting apoptosis. Concurrently, Fe²⁺-mediated Fenton reactions led to lipid peroxide accumulation, triggering ferroptosis. The CFA-MN patch exhibited robust mechanical strength and rapid dissolution for precise delivery and controlled release. In vitro and in vivo results demonstrated significant tumor inhibition through combined apoptosis and ferroptosis pathways. This work highlights the potential of CFA-MN as a multifunctional platform to overcome chemoresistance and improve breast cancer treatment outcomes.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"700 Pt 3","pages":"138558"},"PeriodicalIF":9.7,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144811483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}