Yaohua Huang , Huatong Zhu , Dongyue Peng , Zhixin Liao , Hao Lu , Qiang Yang
{"title":"Generation of high-viscosity heavy oil droplets: Insights from image analysis and numerical simulation","authors":"Yaohua Huang , Huatong Zhu , Dongyue Peng , Zhixin Liao , Hao Lu , Qiang Yang","doi":"10.1016/j.cep.2025.110232","DOIUrl":"10.1016/j.cep.2025.110232","url":null,"abstract":"<div><div>To understand the behavior of high-viscosity heavy oil droplets generated in mass transfer systems, a method was established to measure the microdroplet formation via image analysis, with measurement errors controlled within 10 %. N-dodecane–dimethicone solutions with different viscosities and ethanol–deionized water solutions were employed as dispersed and continuous phases, respectively. The study identifies three stages of microdroplet formation: shrinkage, expansion, and fracture. The pressure and velocity fields during the fracture stage are simulated using a numerical simulation method. The fracture stages of droplets are categorized into three morphologies: fluctuating fracture, equilibrium fracture, and hysteretic fracture, which can be predicted using the <em>Re</em> number and <em>We</em> number. Increasing the viscosity of the dispersed phase increases the droplet formation time. The volume of produced droplets increases as the n-dodecane content in the dispersed phase increases. Finally, the droplet size decreases with an increase in the microdroplet formation time and a decrease in the nozzle size. Experimental results reveal the formation of high-viscosity heavy oil droplets in strong mass transfer solvents and offer prospects for developing micro-reaction technology for heavy crude oil refining.</div></div>","PeriodicalId":9929,"journal":{"name":"Chemical Engineering and Processing - Process Intensification","volume":"211 ","pages":"Article 110232"},"PeriodicalIF":3.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143529729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of 3D-printed electrodes using polyacrylonitrile/ graphene composites for application in polysulfide bromide flow battery","authors":"Rungsima Yeetsorn , Saksitt Chitvuttichot , Adisorn Tuantranont , Tanyakarn Treeratanaphitak , Jeff Gostick","doi":"10.1016/j.cep.2025.110233","DOIUrl":"10.1016/j.cep.2025.110233","url":null,"abstract":"<div><div>The performance of Polysulfide Bromide Flow Batteries (PBS) is depended on the design of the electrodes, which plays a crucial role in ensuring optimal electrolyte distribution and conductivity. These factors are essential for facilitating efficient electrochemical kinetics. This study introduces a novel approach to electrode fabrication using polyacrylonitrile/graphene composites through 3D printing, which enhances structural uniformity and electrical conductivity. The incorporation of reduced graphene oxide, with an electrical conductivity of 23 S/m, into polyacrylonitrile-based electrodes substantially improves their electrical conductivity. Unlike traditional techniques that produce randomly oriented fibers, 3D printing offers precise control over electrode architecture. This enables uniform electrolyte flow, improved mass transfer, and increased electrolyte diffusion across the electrode surface. The precise architectural design ensures that the electrolyte's retention time is aligned with its inert properties and optimizing the electrochemical process. One of the two 3D-printed electrode designs exhibited a diffusion coefficient of 73.85 × 10<sup>-13</sup> m<sup>2</sup>/s. This research not only overcomes the limitations of traditional electrode fabrication techniques but also highlights the potential of advanced 3D printing technologies in the creation of next-generation flow battery electrodes. The findings from this study could pave the way for the development of more efficient, durable, and scalable energy storage systems.</div></div>","PeriodicalId":9929,"journal":{"name":"Chemical Engineering and Processing - Process Intensification","volume":"211 ","pages":"Article 110233"},"PeriodicalIF":3.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143437455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hao Cheng , Guoqiang Cao , Zhongren Ba , Donghai Hu , Yongbin Wang , Guorong Zhu , Chunyu Li , Jiantao Zhao , Yitian Fang
{"title":"Process modeling, simulation and thermodynamic analysis of a novel process integrating coal gasification, smelting reduction and methanol synthesis for ironmaking and methanol co-production","authors":"Hao Cheng , Guoqiang Cao , Zhongren Ba , Donghai Hu , Yongbin Wang , Guorong Zhu , Chunyu Li , Jiantao Zhao , Yitian Fang","doi":"10.1016/j.cep.2025.110231","DOIUrl":"10.1016/j.cep.2025.110231","url":null,"abstract":"<div><div>A novel process integrating coal gasification, smelting reduction, and methanol synthesis process has been proposed and designed to produce both high-quality hot metal and methanol. This process comprises eight key units: Coal Gasification Pre-reduction, Smelting Reduction, Water Gas Shift, Acid Gas Removal, CO<sub>2</sub> Compression and Storage, Gas and Steam Turbine, Methanol Synthesis, and Distillation. The innovative aspect of this process lies in the partial recycling of H<sub>2</sub> rich clean syngas which is generated from the WGS and AGR stages. Key operational parameters based on the feed of coal is 100 tones/h, such as the ore/coal ratio, oxygen/coal ratio, circulation ratio (CR), and oxygen replenishment (OR) were optimized at values of 1.4, 0.8, 0.5, and 10 tons/h, respectively, enabling the co-production of 100 tons of hot metal and 55 tons of methanol. Thermodynamic analysis indicates that the energy consumption, energy efficiency, and exergy efficiency of the CGSRMS system per unit of product (1 t-Fe and 0.55 t-CH<sub>3</sub>OH) are 10.47 GJ, 73.06 %, and 72.12 %, respectively. CO<sub>2</sub> emissions are significantly reduced to 0.91 t/h per unit of product, representing a 51.81 % decrease compared to conventional processes with same production outputs.</div></div>","PeriodicalId":9929,"journal":{"name":"Chemical Engineering and Processing - Process Intensification","volume":"211 ","pages":"Article 110231"},"PeriodicalIF":3.8,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143444311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Environmental life-cycle assessment and green principles in process intensification: A review of novel catalysts from solid waste","authors":"A.V.S.L. Sai Bharadwaj , Ripsa Rani Nayak , J Koteswararao , Chinnam Sampath , Baburao Gaddala , Bharat Govind Pawar , Navneet Kumar Gupta","doi":"10.1016/j.cep.2025.110208","DOIUrl":"10.1016/j.cep.2025.110208","url":null,"abstract":"<div><div>The development of novel catalysts from solid waste has become a key strategy in sustainable research. This review focuses on the environmental life-cycle assessment (LCA) of waste-derived catalysts, highlighting their role in process intensification and alignment with green chemistry principles. LCA is crucial for evaluating the environmental, socioeconomic, and design implications of catalyst production from waste materials. The continuous disposal of solid waste contributes to rising energy demands, environmental degradation, and human health risks, which underscores the need for efficient, green solutions. This review examines the evolution of waste-derived heterogeneous catalysts, emphasizing their significance in the circular economy and sustainable practices. The impact of analytical and physico-chemical properties on both conventional and intensified processes is explored, with reaction time and temperature identified as critical parameters in catalyst synthesis. Conventional catalyst production, often involving high temperatures (>600 to <900°C) and long reaction times (4–5 hours), is energy intensive. However, process intensification, reducing these conditions to <100°C and <100 minutes, offers a sustainable alternative by minimizing energy consumption while maintaining catalyst performance. This review also compares various analytical techniques, such as X-ray diffraction, scanning electron microscopy, and density functional theory, to assess the effectiveness of catalysts produced through intensified methods. The findings suggest that intensified synthesis processes yield results comparable to traditional methods, demonstrating their potential to reduce energy demand and promote sustainability in catalyst production from solid waste.</div></div>","PeriodicalId":9929,"journal":{"name":"Chemical Engineering and Processing - Process Intensification","volume":"211 ","pages":"Article 110208"},"PeriodicalIF":3.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143510752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jan Vehrenberg , Georg Gert , Maren Grosseheide , Matthias Wessling , Robert Keller
{"title":"Paired electrochemical synthesis of Cl2 from alkali chloride and CO from CO2","authors":"Jan Vehrenberg , Georg Gert , Maren Grosseheide , Matthias Wessling , Robert Keller","doi":"10.1016/j.cep.2025.110209","DOIUrl":"10.1016/j.cep.2025.110209","url":null,"abstract":"<div><div>In order to bring electrochemical CO<sub>2</sub> reduction (eCO<sub>2</sub>R) to economical feasibility on an industrial scale, the conventional oxygen evolution reaction (OER) can be replaced with a value added reaction. In this work, we replace OER with chlorine evolution reaction (CER) in a paired synthesis with CO from CO<sub>2</sub>. Hereby, the reaction system is assessed at industrial relevant current densities with respect to electrolyte species & concentration and stability of up to 24 h. We report constant anodic FEs to Cl<sub>2</sub> of <span><math><mo>></mo></math></span>97<span><math><mtext>%</mtext></math></span> for up to 400 <span><math><mrow><mi>mA</mi><mo>/</mo><msup><mrow><mi>cm</mi></mrow><mrow><mn>2</mn></mrow></msup></mrow></math></span> with concurrent FEs to CO of 90<span><math><mtext>%</mtext></math></span> at 100 <span><math><mrow><mi>mA</mi><mo>/</mo><msup><mrow><mi>cm</mi></mrow><mrow><mn>2</mn></mrow></msup></mrow></math></span> and 74<span><math><mtext>%</mtext></math></span> at 200 <span><math><mrow><mi>mA</mi><mo>/</mo><msup><mrow><mi>cm</mi></mrow><mrow><mn>2</mn></mrow></msup></mrow></math></span> over 4.5 h, significantly exceeding previous studies for comparable systems. The FE for CER did not show any decline over 24 h of operation. KCl showed superior results over NaCl and CsCl in terms of cathodic FE and cell potential. CER is affected by educt limitation with FE dropping below 95<span><math><mtext>%</mtext></math></span> at an electrolyte concentration of 0.8 mol/L at 400 <span><math><mrow><mi>mA</mi><mo>/</mo><msup><mrow><mi>cm</mi></mrow><mrow><mn>2</mn></mrow></msup></mrow></math></span>. By successfully pairing eCO<sub>2</sub>R and CER with stable and high FEs at industrially relevant current densities, this work marks an important step towards an industrial application.</div></div>","PeriodicalId":9929,"journal":{"name":"Chemical Engineering and Processing - Process Intensification","volume":"211 ","pages":"Article 110209"},"PeriodicalIF":3.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143452880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Waseem, Nayef Ghasem, Mohamed Al-Marzouqi
{"title":"Experimental and simulation study of a catalytic-membrane integrated system for efficient CO2 stripping","authors":"Muhammad Waseem, Nayef Ghasem, Mohamed Al-Marzouqi","doi":"10.1016/j.cep.2025.110216","DOIUrl":"10.1016/j.cep.2025.110216","url":null,"abstract":"<div><div>Global warming, mainly caused by carbon dioxide (CO<sub>2</sub>) emissions, is rapidly becoming a serious concern. The Carbon Capture, Utilization, and Storage (CCUS) process, particularly the amine-based absorption process, is among the most developed industrial processes for capturing CO<sub>2</sub> from anthropogenic and natural sources. However, the energy-intensive nature of the equipment, as well as its high capital cost, inhibits widespread application. A porous hollow fiber membrane contactor (HFMC) is considered a promising technique for solvent regeneration in CO<sub>2</sub> capture applications. Recent research on catalyst-assisted solvent regeneration has also shown that nano catalytic materials can reduce solvent regeneration energy costs while increasing CO<sub>2</sub> desorption. Therefore, a self-fabricated gas-liquid membrane contactor (GLMC) module integrated with catalytically promoted CO<sub>2</sub> desorption to maximize their potential for solvent regeneration is used in this paper. A polytetrafluoroethylene (PTFE) hollow fiber membrane module combined with and without catalytic stripping is tested for CO<sub>2</sub> stripping performance under varying gas-liquid flowrates, temperatures, and initial CO<sub>2</sub> loading concentrations. Increasing the liquid phase temperature and liquid flowrate significantly improved CO<sub>2</sub> stripping, whereas increasing the gas flowrate did not increase stripping flux as much. Adding nanomaterial increased the stripping efficiency of membrane modules from 53 % to 72 % at 80 °C during CO<sub>2</sub> stripping experiments. Catalytically assisted systems exhibited improved stripping efficiency from 48 % to 65 % when liquid flow rates were increased from 20 mL/min to 100 mL/min. A mathematical model for the fabricated module is developed for CO<sub>2</sub> stripping from rich ethanolamine (MEA) solutions and it is simulated using COMSOL. Model predictions align well with experimental data outcomes.</div></div>","PeriodicalId":9929,"journal":{"name":"Chemical Engineering and Processing - Process Intensification","volume":"211 ","pages":"Article 110216"},"PeriodicalIF":3.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143430047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lina María Grajales , Hailei Wang , Fernanda Perpétua Casciatori , João Claúdio Thoméo
{"title":"Intensified rotary drum bioreactor for cellulase production from agro-industrial residues by solid-state cultivation","authors":"Lina María Grajales , Hailei Wang , Fernanda Perpétua Casciatori , João Claúdio Thoméo","doi":"10.1016/j.cep.2025.110223","DOIUrl":"10.1016/j.cep.2025.110223","url":null,"abstract":"<div><div>Cellulolytic enzymes are vital for converting cellulosic residues into biofuels, yet large-scale production through solid-state cultivation (SSC) remains challenging due to the lack of suitable bioreactors. This study addresses this issue by developing a rotary drum bioreactor to produce cellulases from the thermophilic fungus <em>Myceliophthora thermophila</em> I-1D3b, using sugarcane bagasse and wheat bran as substrates. The bioreactor integrates upstream, fermentation, and downstream processes, streamlining production and enhancing efficiency. The study explored enzymatic activity (EA) at varying substrate loadings and drum rotation conditions. Although statistically similar, at 50 % loading, drum rotation slightly improved EA (49.12 U/mL ± 6.56 U/mL) compared to static conditions (47.78 U/mL ± 8.25 U/mL). Conversely, at 40 % loading, rotation reduced EA significantly (23.57 U/mL ± 3.17 U/mL) compared to static conditions (46.91 U/mL ± 8.17 U/mL). At 60 % loading, EA was similar under both static and rotated conditions. The design effectively supports fermentation, facilitates enzymatic extract recovery, and minimizes temperature and moisture gradients. These results demonstrate the rotary drum bioreactor's potential for scaling up cellulase production, offering a promising solution for industrial SSC processes.</div></div>","PeriodicalId":9929,"journal":{"name":"Chemical Engineering and Processing - Process Intensification","volume":"210 ","pages":"Article 110223"},"PeriodicalIF":3.8,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143420091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melanie Coronel-Muñoz , Ana Gabriela Romero-García , Brenda Huerta-Rosas , Eduardo Sánchez-Ramírez , Juan José Quiroz-Ramírez , Juan Gabriel Segovia-Hernández
{"title":"Assessment of the sustainability of intensified CO2 capture schemes","authors":"Melanie Coronel-Muñoz , Ana Gabriela Romero-García , Brenda Huerta-Rosas , Eduardo Sánchez-Ramírez , Juan José Quiroz-Ramírez , Juan Gabriel Segovia-Hernández","doi":"10.1016/j.cep.2025.110222","DOIUrl":"10.1016/j.cep.2025.110222","url":null,"abstract":"<div><div>The SDGs do address climate-related goals that are interconnected with the need to reduce greenhouse gas emissions. CO<sub>2</sub> capture involves the use of solvents such as Monoethanolamine (MEA), whose use, advantages, and disadvantages are well reported. Currently, there are alternative solvents that are theoretically more sustainable such as deep eutectic solvents (DES), however, a direct comparative with sustainable indicators is not always available. In this work, two schemes for the CO<sub>2</sub> capture process are evaluated and compared in a sustainable framework. Both schemes capture CO<sub>2</sub> from a combustion process to generate electricity. The first scheme considers Monoethanolamine (MEA) and the second scheme considers a DES (ChCl/ urea (1:2), considering in both schemes the use of natural gas, biogas, and coal as fuels that originate the CO<sub>2</sub> flux. The evaluation of both alternatives must be approached in a weighted manner and within a framework of sustainability. The results indicate that there is no single solution as the optimal solvent for CO<sub>2</sub> capture. It was observed that the choice of solvent is predominantly influenced by the type of fuel used in the combustion zone for electricity generation.</div></div>","PeriodicalId":9929,"journal":{"name":"Chemical Engineering and Processing - Process Intensification","volume":"210 ","pages":"Article 110222"},"PeriodicalIF":3.8,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143420088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wenlong Li , Linzheng Ye , XiJing Zhu , Yao Liu , Jialong Wu , Shida Chuai , Zexiao Wang
{"title":"Experimental study of acoustically induced hydroxyl radicals in hydrogen peroxide systems based on fluorescence analysis","authors":"Wenlong Li , Linzheng Ye , XiJing Zhu , Yao Liu , Jialong Wu , Shida Chuai , Zexiao Wang","doi":"10.1016/j.cep.2025.110219","DOIUrl":"10.1016/j.cep.2025.110219","url":null,"abstract":"<div><div>The hydroxyl radical (·OH), an extremely reactive oxidizing agent, can interact with both brittle and hard materials, such as single-crystal silicon carbide (SiC), facilitating material removal via ultrasonic-assisted chemical mechanical polishing (UCMP). It is crucial to explore the generation mechanism of acoustically induced ·OH radicals within the UCMP process. This study investigated the influence of ultrasonic duration, initial solution temperature, frequency, power, and initial hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) concentration on the ·OH radical yield in the H<sub>2</sub>O<sub>2</sub> system based on fluorescence analysis. Furthermore, it elucidates the quantitative relationships between the parameters and ·OH radical generation. The experimental data showed that ultrasonic vibrations significantly enhanced the decomposition of H<sub>2</sub>O<sub>2</sub>, with the ultrasonic duration being key to ·OH radical production, increasing 32.42 times in 30 min without a water-bath. Water-bath conditions reduce the thermal effects, yielding ·OH at a rate of 0.1826. The initial temperature had little impact within a specific range, and the peaking ·OH yield increased at 0.0662 from 20 to 50 °C. Lower frequencies and higher powers enhanced the ·OH yield by 5.37 to 10.126 times. Low H<sub>2</sub>O<sub>2</sub> concentrations produced high ·OH radicals, peaking at 3.753 μmol/L at 1.5 wt%. These results are vital for improving UCMP efficiency and surface quality.</div></div>","PeriodicalId":9929,"journal":{"name":"Chemical Engineering and Processing - Process Intensification","volume":"210 ","pages":"Article 110219"},"PeriodicalIF":3.8,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143403057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iman Aslani, Mahdi Khatibi, Seyed Nezameddin Ashrafizadeh
{"title":"Optimizing the microchannel geometry for effective control of analyte band dispersion","authors":"Iman Aslani, Mahdi Khatibi, Seyed Nezameddin Ashrafizadeh","doi":"10.1016/j.cep.2025.110221","DOIUrl":"10.1016/j.cep.2025.110221","url":null,"abstract":"<div><div>Managing analyte band dispersion is a critical challenge in diagnostic systems, medical spectroscopy, chromatography, and drug delivery devices. Effective dispersion control ensures reliable measurements, enhanced resolution, heightened sensitivity, and improved system performance. This study emphasizes the importance of optimizing microchannel geometries, particularly curvature sections, to effectively control analyte band dispersion. To achieve this, four microchannel geometries, namely Type I to Type IV, each with distinct curvature differences, were analyzed to identify the optimal geometry with the lowest dispersion. Key parameters, including wall zeta potential, applied voltage, and the internal-to-external curvature radius ratio, were examined for their influence on dispersion. The finite element method was employed to solve the Laplace and Navier-Stokes equations for electric field and velocity distributions, while the unsteady-state diffusion-convection equation determined analyte concentration profiles. Results showed that dispersion reductions after optimization were 60 % for Type II, 48 % for Type III, and 32 % for Type IV microchannels, nevertheless for Type I microchannel dispersion remain constant after and before optimization about 70 %. Increasing the zeta potential from ζ = -0.1 V to ζ = -0.5 V led to a significant rise in dispersion from 25 % to 90 % post-optimization. Conversely, adjusting the curvature ratio R<sub>r</sub> from 0.1 to 0.5 decreased dispersion from 42 % to 15 %. These findings underscore the importance of precise dispersion control in advancing analytical systems such as lab-on-disk and lab-on-chip technologies. This research provides valuable insights for optimizing microchannel designs to enhance the performance and reliability of various analytical and diagnostic applications.</div></div>","PeriodicalId":9929,"journal":{"name":"Chemical Engineering and Processing - Process Intensification","volume":"210 ","pages":"Article 110221"},"PeriodicalIF":3.8,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143420089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}