ChemistryOpen最新文献_第3页

Multicomponent Synthesis of C(8)-Substituted Purine Building Blocks of Peptide Nucleic Acids from Prebiotic Compounds. 用前生物化合物多组分合成肽核酸的 C(8)- 取代嘌呤基块。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2024-10-17 DOI: 10.1002/open.202400265

Eleonora Mancin, Eliana Capecchi, Lorenzo Botta, Bruno Mattia Bizzarri

{"title":"Multicomponent Synthesis of C(8)-Substituted Purine Building Blocks of Peptide Nucleic Acids from Prebiotic Compounds.","authors":"Eleonora Mancin, Eliana Capecchi, Lorenzo Botta, Bruno Mattia Bizzarri","doi":"10.1002/open.202400265","DOIUrl":"https://doi.org/10.1002/open.202400265","url":null,"abstract":"We have explored the reaction of a three-components mixture of aminomalononitrile, urea and α-amino acid methyl esters for the multicomponent synthesis substituted purines resembling PNA's building blocks. 2,6-diamino-purines, 6-amino-3,9-dihydro-2H-purin-2-one (iso-guanines), and 3,9-dihydro-6H-purin-6-one derivatives, selectively decorated at C(8)-position of the purine ring with different amino acid residues, were obtained from acceptable to good yields. The regio-selectivity of the transformation was controlled by the use of urea in the ternary mixture and by the annulation agent involved in the ring-closure of amino-imidazole carbonitrile intermediates. Solvent free conditions, microwave irradiation and simple one-carbon containing reagents further satisfied the major requirement of atom economy and sustainable chemistry. Due to the prebiotic nature of the three-components mixture and of annulation agents, it also embodies the possibility for the synthesis of novel PNAs bearing purine nucleobases decorated at C(8)-position of the imidazole ring as alternative RNA analogues in molecular evolution.","PeriodicalId":9831,"journal":{"name":"ChemistryOpen","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First Principles Study of Electronic and Optical Properties of Al-P Co-Doped ZnO in the Presence of Zn Vacancies. 存在锌空位时 Al-P 共掺氧化锌的电子和光学特性的第一原理研究》（First Principles Study of Electronic and Optical Properties of Al-P Co-Doped ZnO in the Presence of Zn Vacancies）。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2024-10-17 DOI: 10.1002/open.202400222

Zhengguang Guo, Yonghong Yao, Jin Liu

引用次数: 0

New Ibuprofen Cystamine Salts With Improved Solubility and Anti-Inflammatory Effect. 具有更好溶解性和抗炎效果的新型布洛芬胱胺盐。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2024-10-14 DOI: 10.1002/open.202400206

Simay Denizkusu, Ece Sabuncu, Hande Sipahi, Duygu Avci

引用次数: 0

Conversion of Cellobiose to Formic Acid as a Biomass-Derived Renewable Hydrogen Source Using Solid Base Catalysts. 使用固体基催化剂将纤维生物糖转化为甲酸，作为生物质衍生的可再生氢源。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2024-10-07 DOI: 10.1002/open.202400079

Ikuto Yoshiki, Atsushi Takagaki, Jun Tae Song, Motonori Watanabe, Tatsumi Ishihara

{"title":"Conversion of Cellobiose to Formic Acid as a Biomass-Derived Renewable Hydrogen Source Using Solid Base Catalysts.","authors":"Ikuto Yoshiki, Atsushi Takagaki, Jun Tae Song, Motonori Watanabe, Tatsumi Ishihara","doi":"10.1002/open.202400079","DOIUrl":"https://doi.org/10.1002/open.202400079","url":null,"abstract":"Formic acid is considered a promising hydrogen carrier. Biomass-derived formic acid can be obtained by oxidative decomposition of sugars. This study explored the production of formic acid from cellobiose, a disaccharide consisting of d-glucose linked by β-glycosidic bonds using heterogeneous catalysts under mild reaction conditions. The use of alkaline earth metal oxide solid base catalysts like CaO and MgO in the presence of hydrogen peroxide could afford formic acid from cellobiose at 343 K. While CaO gave 14 % yield of formic acid, the oxide itself was converted to a harmful metal peroxide, CaO2 after the reaction. In contrast, MgO could produce formic acid without the formation of the metal peroxide. The difficulty in selectively synthesizing formic acid from cellobiose using these solid base catalysts was due to the poor conversion of cellobiose to glucose. Using a combination of solid acid and base catalysts, a high formic acid yield of 33 % was obtained under mild reaction conditions due to the quantitative hydrolysis of cellobiose to glucose by a solid acid followed by the selective decomposition of glucose to formic acid by a solid base.","PeriodicalId":9831,"journal":{"name":"ChemistryOpen","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142388414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Front Cover: Quantitative Spermidine Detection in Cosmetics using an Organic Transistor-Based Chemical Sensor (ChemistryOpen 10/2024) 封面：利用基于有机晶体管的化学传感器定量检测化妆品中的精胺（ChemistryOpen 10/2024）

IF 2.5 4区化学

ChemistryOpen Pub Date : 2024-10-07 DOI: 10.1002/open.202481001

Dr. Yui Sasaki, Kohei Ohshiro, Miyuki Kato, Hikaru Tanaka, Akari Yamagami, Dr. Kazutake Hagiya, Prof. Dr. Tsuyoshi Minami

引用次数: 0

Green Synthesis of Zinc Oxide Nanoparticles Using Dillenia Indica and Mikania Micrantha Leaf Extracts: Applications in Photocatalysis and Antibacterial Activity. 利用印度莳萝和薇甘菊叶提取物绿色合成纳米氧化锌颗粒：光催化和抗菌活性中的应用。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2024-10-02 DOI: 10.1002/open.202400102

Protap Kumar Pal, Md Sarifujjaman, Prianka Saha, S M Mahbubur Rahman, Md Emdadul Islam, Bashir Ahmmad, Kaykobad Md Rezaul Karim, Md Mahiuddin

{"title":"Green Synthesis of Zinc Oxide Nanoparticles Using Dillenia Indica and Mikania Micrantha Leaf Extracts: Applications in Photocatalysis and Antibacterial Activity.","authors":"Protap Kumar Pal, Md Sarifujjaman, Prianka Saha, S M Mahbubur Rahman, Md Emdadul Islam, Bashir Ahmmad, Kaykobad Md Rezaul Karim, Md Mahiuddin","doi":"10.1002/open.202400102","DOIUrl":"https://doi.org/10.1002/open.202400102","url":null,"abstract":"Researchers are keenly interested in developing metal-based nanoparticles using plant sources as they are eco-friendly, less expensive and simpler. Zinc oxide nanoparticles, symbolized as D-ZnONPs and M-ZnONPs were synthesized in this study utilizing the leaves of D. indica and M. micrantha, respectively, and studied their impact on the growth inhibition of various bacterial strains and on the photocatalysis. By displaying the distinctive surface plasmon resonance (SPR) band at 373 nm in UV-Vis and bands at 450-480 cm-1 corresponding to Zn-O stretching FTIR spectroscopy imparted the formation of ZnONPs which was further supported by X-ray diffraction analysis by showing the polycrystalline nature and a hexagonal wurtzite structure. The spherical form and average particle size of 30 nm of the produced ZnONPs, as confirmed by electron microscopy, are also confirmed to be crystalline. Under natural sunlight, both ZnONPs demonstrate excellent degradation efficacy about 96-99 % within 100 min towards methylene blue (MB). Furthermore, it is noteworthy that both the synthesized ZnONPs exhibited 55-60 % efficacy with respect to antibiotics in inhibiting the growth of various pathogenic bacterial strains. Overall, ZnONPs can be produced on a large-scale using plant sources and employed them in environmental remediation and cosmetic industries as prominent components.","PeriodicalId":9831,"journal":{"name":"ChemistryOpen","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Tricyclic Aryl Quinazoline Derivatives by Suzuki-Miyaura Cross-Coupling. 通过 Suzukii-Miyaura 交叉偶联生成新的三环芳基喹唑啉衍生物。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2024-09-27 DOI: 10.1002/open.202400197

Burkhon Elmuradov, Rasul Okmanov, Bakhromjon Juraev, Gerald Dräger, Holger Butenschön

引用次数: 0

Time-of-Flight Secondary Ion Mass Spectrometry Revealing the Organocatalyst Distribution in Functionalized Silica Monoliths. 飞行时间二次离子质谱法揭示功能化二氧化硅单片中的有机催化剂分布。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2024-09-27 DOI: 10.1002/open.202400199

Raoul D Brand, Julia S Schulze, Anja Henss, Bernd M Smarsly

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Impact of Ligand Design on an Iron NHC Epoxidation Catalyst 配体设计对铁 NHC 环氧化催化剂的影响