ChemistryOpen最新文献

Studies Concerned with the Structure and Synthesis of the Anti-viral Tropolone Glycoside Liriosmaside A. 抗病毒Tropolone糖苷liriosm苷A的结构与合成研究。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2025-04-08 DOI: 10.1002/open.202500011

Qi Chen, Yaping Zhan, Michael G Gardiner, Zeinab G Khalil, Amila A Dewa, Thulasi Sritharan, Robert J Capon, Ping Lan, Shen Tan, Martin G Banwell

{"title":"Studies Concerned with the Structure and Synthesis of the Anti-viral Tropolone Glycoside Liriosmaside A.","authors":"Qi Chen, Yaping Zhan, Michael G Gardiner, Zeinab G Khalil, Amila A Dewa, Thulasi Sritharan, Robert J Capon, Ping Lan, Shen Tan, Martin G Banwell","doi":"10.1002/open.202500011","DOIUrl":"https://doi.org/10.1002/open.202500011","url":null,"abstract":"A bromotropone corresponding to the agylcone of the glycosylated sesquiterpenoid natural product liriosmaside A has been prepared over ten steps and in a fully regio-controlled manner through the gem-dibromocyclopropane-mediated ring-expansion of a readily accessible decalenone. A Pd[0]-mediated glucosylation reaction applied to this bromotropone afforded a product mixture from which an enantiomerically pure cross-coupling product could be obtained and its structure confirmed through single-crystal X-ray analysis of a derivative. Various (unsuccessful) attempts are described to selectively acylate the last compound and thereby install the 3-hydroxy-3-methylglutaric acid or HMGA-containing side chain of the title natural product. A literature survey of other natural products embodying the HMGA motif suggest that liriosmaside A and its co-metabolite liriosmaside B could be S-configured at C3\". The evaluation of the glucosylated tropone in a series of anti-bacterial, anti-fungal and cytotoxicity assays reveals that it is inactive in all of these and so emphasizing the prospect that this and related troponoids, including the natural products liriosmaside A and B, can serve as useful models for new anti-viral agents.","PeriodicalId":9831,"journal":{"name":"ChemistryOpen","volume":" ","pages":"e202500011"},"PeriodicalIF":2.5,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enzyme-Substrate Complex Formation and Electron Transfer in Nitrogenase-Like Dark-Operative Protochlorophyllide Oxidoreductase (DPOR). 酶-底物复合物在氮酶样暗操作原叶绿内酯氧化还原酶（DPOR）中的形成和电子转移。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2025-04-08 DOI: 10.1002/open.202500153

Giada Bedendi, Plinio Maroni, Ross D Milton

{"title":"Enzyme-Substrate Complex Formation and Electron Transfer in Nitrogenase-Like Dark-Operative Protochlorophyllide Oxidoreductase (DPOR).","authors":"Giada Bedendi, Plinio Maroni, Ross D Milton","doi":"10.1002/open.202500153","DOIUrl":"https://doi.org/10.1002/open.202500153","url":null,"abstract":"Nitrogenase-like dark-operative protochlorophyllide oxidoreductase (DPOR) is a two-component metalloenzyme involved in (bacterio)chlorophyll biosynthesis. DPOR enables photosynthesis in photosynthetic bacteria by catalyzing the MgATP hydrolysis-dependent, stereoselective two-electron reduction of protochlorophyllide (Pchlide) to chlorophyllide (Chlide). This requires the repeated transient association of DPOR's two component proteins (BchL and BchNB), and involves a series of individual and unresolved sequence of events (including MgATP-hydrolysis, electron transfer, protein association/dissociation, substrate binding, etc.). DPOR shares structural and mechanistic similarities with nitrogenase, although the spectroscopic properties of Pchlide and Chlide permit the reaction to be followed in situ with visible spectroscopy. Here, we investigate DPOR's mechanism through vis-spectroscopy in the absence of an electron donor in the system, where we were able to observe the formation of the enzyme-substrate (ES) complex prior to substrate reduction (electron transfer and MgATP hydrolysis). The determination of rate constants for ES formation as well as overall electron transfer reveals the complex rate-limiting interplay between these two processes. Further, we observe evidence of cooperativity for ES complex formation in DPOR, which may be the origin of cooperativity during enzymatic turnover.","PeriodicalId":9831,"journal":{"name":"ChemistryOpen","volume":" ","pages":"e202500153"},"PeriodicalIF":2.5,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Front Cover: Hydrogen Storage and Release via Carbon Dioxide Hydrogenation to Formate Salts under High-Pressure Conditions with Ir Complex and Subsequent Formic Acid Dehydrogenation (ChemistryOpen 4/2025) 封面：高压条件下二氧化碳加氢生成甲酸盐和随后甲酸脱氢的氢气储存和释放（化学开放4/2025）

IF 2.5 4区化学

ChemistryOpen Pub Date : 2025-04-07 DOI: 10.1002/open.202580401

Seo Ono, Dr. Ryoichi Kanega, Prof. Hajime Kawanami

引用次数: 0

Structural and Optical Characterization of Pure and Lanthanum Substituted Nd_1-xLa_xAlO₃ Prepared by Sol-Gel Method. 溶胶-凝胶法制备纯和镧取代Nd1-xLaxAlO3的结构和光学表征。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2025-04-07 DOI: 10.1002/open.202400499

Akash S Padole, Vikash Singar, Payal Ratnawat, Ansh Dabkara, Dibya Prakash Kar, Nikita Jain, Minal Gupta, Archna Sagdeo, Pankaj R Sagdeo

{"title":"Structural and Optical Characterization of Pure and Lanthanum Substituted Nd1-xLaxAlO3 Prepared by Sol-Gel Method.","authors":"Akash S Padole, Vikash Singar, Payal Ratnawat, Ansh Dabkara, Dibya Prakash Kar, Nikita Jain, Minal Gupta, Archna Sagdeo, Pankaj R Sagdeo","doi":"10.1002/open.202400499","DOIUrl":"https://doi.org/10.1002/open.202400499","url":null,"abstract":"This work demonstrates the tuning of crystal-field parameters of Nd rare Earth ion in NdAlO3 through lanthanum (La) substitution; for this purpose, this work has prepared the polycrystalline samples of pure and La-substituted NdAlO3 using the sol-gel synthesis method. The purity of the phase of Nd1-xLaxAlO3 (x = 0, 0.1, 0.2, 0.3, 0.4, 0.5) samples has been confirmed via X-ray diffraction measurements. This work found that with La substitution, the lattice parameters systematically increase. The values of lattice parameters \"a\" and \"b\" changed from 5.315 Å (x = 0) to 5.339 Å (x = 0.5). The lattice parameter \"c\" also increased from 12.926 to 13.025 Å in these samples. Additionally, the Nd/LaO bond length increased from 2.419 to 2.469 Å. The NdONd bond angle shifted from 169.7° to 171.4°, whereas the AlOAl bond angle varies from 165.5° to 167.8° and the value of the tolerance factor from 0.9640 to 0.9700, indicating improvement in the structural distortion. The crystal-field transitions are investigated using optical absorption spectroscopy; this work found that La-substitution leads to changes in the transition peak 4F9/2, which is shifted from 676.99 nm for sample (x = 0) to 675.44 nm for sample (x = 0.5).","PeriodicalId":9831,"journal":{"name":"ChemistryOpen","volume":" ","pages":"e2400499"},"PeriodicalIF":2.5,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of Deferoxamine-Functionalized Cyclodextrin Polymer for Targeted Iron Chelation. 铁铁胺功能化环糊精靶向铁螯合聚合物的研制。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2025-04-07 DOI: 10.1002/open.202500186

Roberta Panebianco, Maurizio Viale, Graziella Vecchio

引用次数: 0

Exploring a Water-Ethyl Acetate System for the Efficient Synthesis of 4-Aryl Quinolines. 水-乙酸乙酯体系高效合成4-芳基喹啉的研究。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2025-04-07 DOI: 10.1002/open.202400470

Mohammad Qandalee, Aliyeh Khajeh-Khezri, Mohammad Alikarami, Silvia Izquierdo, Ignacio M López-Coca

引用次数: 0

A Comparison of the Electrochemical Oxidative Dissolution of Pyrite and Chalcopyrite in Dilute Nitric Acid Solution. 黄铁矿和黄铜矿在稀硝酸溶液中的电化学氧化溶解比较。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2025-04-02 DOI: 10.1002/open.202400053

Samaneh Teimouri, Johannes Herman Potgieter, Caren Billing

{"title":"A Comparison of the Electrochemical Oxidative Dissolution of Pyrite and Chalcopyrite in Dilute Nitric Acid Solution.","authors":"Samaneh Teimouri, Johannes Herman Potgieter, Caren Billing","doi":"10.1002/open.202400053","DOIUrl":"https://doi.org/10.1002/open.202400053","url":null,"abstract":"Understanding the oxidation of sulfidic minerals, especially those of pyrite and chalcopyrite, under acidic conditions has important outcomes, such as exposing any encapsulated gold not recovered by traditional cyanidation processes. This study focused on the electrochemical oxidation of pyrite and chalcopyrite in a 0.5 M nitric acid solution. Electrochemical techniques were employed, using the minerals as working electrodes. Cyclic voltammetry (CV) was performed to detect redox processes and resulting products were suggested. Electrochemical impedance spectroscopy (EIS) was run at specific potentials corresponding to oxidation processes detected to further probe the reaction mechanism. For pyrite at low anodic potentials (0.4-0.6 V vs Ag/AgCl), Fe1-xS2 and Fe(OH)3 with a sulfur-rich layer which forms S0 accumulates on the electrode surface, leading to diffusion controlled dissolution processes. Above 0.7 V, the pyrite is fully oxidised, eradicating the diffusion barrier and extensive oxidation occurs at high potentials (0.9 V). Similar processes occurred for chalcopyrite with mainly iron-deficient sulfides (like Cu1-xFe1-yS2-z, CuS2, CuS) forming at low potentials (0.3-0.5 V), and S0 partially covering the surface causing a diffusion barrier. Increasing the potential to beyond 0.7 V leads to these layers converting to soluble species.","PeriodicalId":9831,"journal":{"name":"ChemistryOpen","volume":" ","pages":"e202400053"},"PeriodicalIF":2.5,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Soft-Template Electropolymerization from Triphenylamine-Based Monomers: From Vertically Aligned Nanotubes to Nanomembranes. 三苯胺基单体的软模板电聚合：从垂直排列的纳米管到纳米膜。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2025-04-01 DOI: 10.1002/open.202500050

Khady Diouf, Alioune Diouf, Abdoulaye Dramé, Frédéric Guittard, Thierry Darmanin

{"title":"Soft-Template Electropolymerization from Triphenylamine-Based Monomers: From Vertically Aligned Nanotubes to Nanomembranes.","authors":"Khady Diouf, Alioune Diouf, Abdoulaye Dramé, Frédéric Guittard, Thierry Darmanin","doi":"10.1002/open.202500050","DOIUrl":"https://doi.org/10.1002/open.202500050","url":null,"abstract":"We report a bioinspired approach to tune surface nanostructures by soft-template electropolymerization in micellar condition. Monomers highly favoring π-stacking interactions are particularly interesting for depositing in one direction resulting in vertically aligned nanotubes. Here, for inducing very strong π-stacking interactions, a triphenylamine building block was selected and substituted by two substituents of different electronegativity (fluorine F and methoxy OMe). These synthons were di-substituted with various fully conjugated thiophene and carbazole derivatives. Here, all the monomers have high electrodeposition capacity except the monomers with thiophene in 3-position. Confirming previous works, electrochemical analyses in the electrodeposited films show the presence of monomers but with significant difference as a function of the used monomer. The surface structures are highly depending on the monomer structure while the depositions at constant potential lead to more ordered structures. With some of these monomers, densely packed nanotubes are created and their merger at high deposition charge, leading to nanomembranes. Their hydrophobicity and oleophobicity are also investigated and extremely various. Such materials could be used in the future in practical applications such as in oil/water separation membranes or in water-harvesting systems.","PeriodicalId":9831,"journal":{"name":"ChemistryOpen","volume":" ","pages":"e202500050"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative Modelling of Biohydrogen Production from Indian Agricultural Residues via Dark Fermentation. 通过暗发酵从印度农业残留物生产生物氢的定量建模。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2025-03-29 DOI: 10.1002/open.202400095

Tanmay J Deka, Ahmed I Osman, Mohamed Farghali, Ahmed Alengebawy, Debendra C Baruah, David W Rooney

{"title":"Quantitative Modelling of Biohydrogen Production from Indian Agricultural Residues via Dark Fermentation.","authors":"Tanmay J Deka, Ahmed I Osman, Mohamed Farghali, Ahmed Alengebawy, Debendra C Baruah, David W Rooney","doi":"10.1002/open.202400095","DOIUrl":"https://doi.org/10.1002/open.202400095","url":null,"abstract":"BioH2, a modern biofuel with clean energy attributes and effective waste management capabilities, emerges as a promising energy source. This study employs quantitative modelling to evaluate India's bioH2 production potential from major crop residues. Among the seven selected crop residues, West Bengal, Uttar Pradesh, and Karnataka stand out as the top three states with surplus crop residues. The annual estimated bioH2 generation potential, without pretreatment, reaches approximately 103 PJ, a figure that soars to around 300 PJ with pretreatment, representing a remarkable 191 % improvement. The study underscores the effectiveness of pretreatment methods involving acid, alkali, or heat in enhancing bioH2 production. Despite these promising findings, efficiency-related challenges, including temperature, pH, and pretreatment factors, are recognised. The study proposes further research and decentralised production projects as potential strategies to address these challenges, enhancing India's energy security by reducing dependence on imported fossil fuels.","PeriodicalId":9831,"journal":{"name":"ChemistryOpen","volume":" ","pages":"e202400095"},"PeriodicalIF":2.5,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multi-Mode Triboelectric Nanogenerator for Football Impact Monitoring and Mechanical Energy Harvesting. 用于足球冲击监测和机械能收集的多模摩擦电纳米发电机。

IF 2.5 4区化学

ChemistryOpen Pub Date : 2025-03-29 DOI: 10.1002/open.202400465

Xi Chen, Xiaolong Yu

{"title":"Multi-Mode Triboelectric Nanogenerator for Football Impact Monitoring and Mechanical Energy Harvesting.","authors":"Xi Chen, Xiaolong Yu","doi":"10.1002/open.202400465","DOIUrl":"https://doi.org/10.1002/open.202400465","url":null,"abstract":"The integration of digital products and sensors significantly enhances motion monitoring accuracy, addressing the limitations of hawk-eye technology. Triboelectric nanogenerators (TENGs) provide innovative, low-cost solutions for developing intelligent digital motion monitoring systems. In this study, we designed a multi-mode triboelectric nanogenerator (M-TENG) that incorporates multiple working modes, enabling switching between internal electrodes to adjust the output mode. This dual working mode enhances the adaptability of the device for football monitoring applications. The versatile design allows the M-TENG to perform both energy harvesting and trigger-based sensing and monitoring, contributing to the advancement of digital intelligence movement technologies. After optimization, the M-TENG achieved a transferred charge (Qsc) of 88.38 nC, short-circuit current (Isc) of 8.58 μA, and open-circuit voltage (Voc) of 85.91 V, showcasing excellent electrical performance. The device charged a 1 μF capacitor to 5 V in 36 seconds, delivering a peak power of 178 μW, and maintained stable output with only a 14 % decrease over 60 days. Additionally, the M-TENG effectively detects and harvests energy from football impacts, generating consistent voltage signals from each interaction, making it a promising candidate for real-time sports equipment monitoring without the need for an external power source.","PeriodicalId":9831,"journal":{"name":"ChemistryOpen","volume":" ","pages":"e202400465"},"PeriodicalIF":2.5,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0