中国实用医药最新文献_第3页

Clinical manifestations of non-compact left ventricular myocardium 左室非致密性心肌的临床表现

中国实用医药 Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-4-132-135

S. N. Ivanova, L. A. Galashevskaya, V. O. Martynov

引用次数: 0

Natural childbirth with a scar on the uterus: clinical practice 子宫瘢痕自然分娩:临床实践

中国实用医药 Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-2-63-67

L. Savina, А. Yashchuk, A. Maslennikov, A. M. Savin

引用次数: 0

Effectiveness of anticoagulants in the prevention of thrombotic complications in patients with cardiovascular pathology who have had COVID-19 抗凝剂在预防COVID-19心血管病变患者血栓性并发症中的有效性

中国实用医药 Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-4-55-62

E. S. Klyachina, O. Smolenskaya, S. S. Vedenskaya

{"title":"Effectiveness of anticoagulants in the prevention of thrombotic complications in patients with cardiovascular pathology who have had COVID-19","authors":"E. S. Klyachina, O. Smolenskaya, S. S. Vedenskaya","doi":"10.32000/2072-1757-2023-4-55-62","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-4-55-62","url":null,"abstract":"At the moment, there is a lot of data demonstrating the effectiveness of anticoagulants in the acute period of COVID-19; as for their effectiveness in patients after discharge, there are relatively few data, especially in patients with concomitant cardiological pathology. The purpose — is to evaluate the relationship of taking anticoagulants, within one month after discharge, with the development of cardiovascular events and deaths in patients with cardiovascular pathology during 3 months of follow-up. Material and methods. A retrospective, cohort, observational study of 317 patients who had COVID-19 and had a history (before COVID-19) of cardiovascular pathology was conducted. Results. Within three months after discharge from the hospital, 15 (4.73%) cardiovascular events were registered. The frequency of arterial thrombotic complications was 3.79% (n = 12), venous thrombotic complications 0.95% (n = 3). All cardiovascular events were reported in patients not using anticoagulants (n = 15; 6.28%), p = 0.026. When analyzing concomitant cardiovascular pathology in patients with registered events, it was revealed that the incidence of atrial fibrillation and ischemic stroke in their anamnesis was statistically significantly higher (33.33 and 40%), relative to the comparison group (10.03 and 7.9%; p = 0.002; p = 0.001, respectively). Conclusions. The use of anticoagulants in patients with cardiovascular pathology during treatment in a COVID hospital and within one month after discharge was associated with a significant decrease in thromboembolic events over 3 months of follow-up. Predictors of thromboembolic events in patients with cardiovascular pathology and those who have had COVID-19 are: senior age; atrial fibrillation and ischemic stroke in the anamnesis.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83801532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of intestinal permeability by triple sugar test in patients with autoimmune liver diseases 三糖试验评价自身免疫性肝病患者肠通透性

中国实用医药 Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-3-48-54

D. Akberova, A. K. Odintsоva, D. Abdulganieva

{"title":"Evaluation of intestinal permeability by triple sugar test in patients with autoimmune liver diseases","authors":"D. Akberova, A. K. Odintsоva, D. Abdulganieva","doi":"10.32000/2072-1757-2023-3-48-54","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-48-54","url":null,"abstract":"We evaluated intestinal permeability by triple sugar test in patients with autoimmune liver diseases. Patients were divided into groups with autoimmune hepatitis, primary biliary cholangitis and overlap syndrome (autoimmune hepatitis/primary biliary cholangitis). 102 people were included in the cross-sectional study: 72 patients with autoimmune liver diseases and 30 healthy volunteers. Diagnose based on recommendations — EASL (2017), AASLD (2019), IAIHG (2021). Small intestine permeability was evaluated by the ratio of lactulose/mannitol in urine, large bowel permeability by the level of sucralose in urine (nmol/l). We used the method of high-performance liquid chromatography–mass spectrometry. Patients with autoimmune liver diseases had increased small intestine permeability – 0.12 [0.07; 0.234] (p < 0.001) compared to the control group — 0.013 [0.01; 0.025]. Large bowel permeability — 760.8 [386.4; 1640] nmol/l did not differ from group control — 785.6 [408; 1027.2]. Increased small intestine permeabilityin patients with autoimmune liver diseases: stage of hepatitis — 0.17 [0.118; 0.253] (p < 0.001), liver cirrhosis — 0.106 [0.07; 0.23] (p < 0.001) compared with the control group. Large bowel permeability in patients with hepatitis and in liver cirrhosis did not differ from control group. Increased values of the triple sugar test were detected in patients with autoimmune hepatitis (increased permeability of the small intestine (0,09 [0,07; 0,17] (p < 0.05), increased permeability of large bowel — 1091,2 [760; 2352] (p < 0.05)) and overlap syndrome (increased small intestine permeability — 0.18 [0,086; 0,3] (p < 0,05) and increased large bowel permeability — 880 [424; 1680] (p < 0,05)) at the stage of liver cirrhosis. Patients with autoimmune liver diseases show the increased permeability of the small intestine. The presence of increased permeability of the small and large intestine may indicate the progression of the disease.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83231480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical case of subcutaneous calcification in a patient with dermatomyositis 皮肌炎患者皮下钙化1例临床分析

中国实用医药 Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-3-150-153

A. A. Shafigullina, E. Kirillova, E. Sukhorukova, R. Abdrakipov

引用次数: 0

Comparative study of the histological structure of the mucous membrane in the norm, in cystic lesions of the paranasal sinuses and in chronic sinusitis 正常人、副鼻窦囊性病变及慢性鼻窦炎患者粘膜组织学结构的比较研究

中国实用医药 Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-2-58-62

E. Pokrovskaya, V. Krasnozhen, S. Polischuck, D. Tsyplakov

{"title":"Comparative study of the histological structure of the mucous membrane in the norm, in cystic lesions of the paranasal sinuses and in chronic sinusitis","authors":"E. Pokrovskaya, V. Krasnozhen, S. Polischuck, D. Tsyplakov","doi":"10.32000/2072-1757-2023-2-58-62","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-2-58-62","url":null,"abstract":"Chronic sinusitis is one of the most common pathologies in the structure of the incidence of ENT organs. The purpose — to study and compare the features of the histological structure of the sinus mucosa in normal and chronic pathological conditions. Material and methods. The study included 30 patients with maxillary sinus cyst and 30 patients with chronic maxillary sinusitis. Immunomorphological studies of the normal mucosa of the maxillary sinus, cyst membrane, hyperplastic mucosa of the maxillary sinus in chronic sinusitis were carried out. All samples were subjected to immunohistochemical staining with further comparison of the results obtained. Results. When comparing all samples, no statistically significant differences were found in the content of macrophages when comparing the normal mucosa and cyst membrane, as well as the content of T-lymphocytes and neutrophils when comparing the cyst membrane and mucosa in chronic sinusitis. All other parameters (the content of neutrophils, macrophages, T and B lymphocytes, mast and goblet cells, the area of non-cellular tissue structures) had significant differences when compared in all groups. Conclusions. Inflammatory changes are observed in the cyst shell, which have significant differences both from the normal mucous membrane and from the mucous membrane in chronic sinusitis.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"43 12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82864675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diseases of civilization — origins in childhood 文明疾病——起源于童年

中国实用医药 Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-4-8-15

S. V. Maltsev

引用次数: 0

Computed tomography and ultrasound examination in the diagnosis of necrotizing fasciitis 计算机断层扫描和超声检查在坏死性筋膜炎诊断中的价值

中国实用医药 Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-4-126-131

D. A. Doroshenko, S. V. Goryunov, I. A. Chizh, O. E. Pshennova

{"title":"Computed tomography and ultrasound examination in the diagnosis of necrotizing fasciitis","authors":"D. A. Doroshenko, S. V. Goryunov, I. A. Chizh, O. E. Pshennova","doi":"10.32000/2072-1757-2023-4-126-131","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-4-126-131","url":null,"abstract":"The purpose — to demonstrate the capabilities of computed tomography and ultrasound in the diagnosis and treatment planning of a patient with a rare case of necrotizing fasciitis. Material and methods. A clinical observation of a 57-year-old patient K. with complaints of pain in the area of the right foot, reddening of the skin on the right foot is presented. T — 37.2 ºC. To determine the nature of the revealed changes, the patient was referred to the Department of Radiation and Functional Diagnostic Methods for soft tissue ultrasound and computed tomography (CT) of the vessels of the lower extremities to assess the lesion and plan surgical treatment. Results. After an ultrasound of the soft tissues of the right leg posterior surface, around the gastrocnemius muscle, an inhomogeneous liquid rim (an echo picture of fasciitis), soft tissue edema was visualized. CT of the lower extremities vessels showed a decrease in blood flow in the lower leg arteries, infiltration and a moderate amount of gas in the soft tissues of n/3 of the lower leg and foot. Discussion. Necrotizing fasciitis (fasciitis necrotisans) is a representative of a large group of surgical infections of soft tissues, the morphological basis of which is progressive necrosis of the superficial fascia (fascia superficialis) and subcutaneous adipose tissue, and the clinical course is particularly severe and is accompanied by high mortality. NF is an emergency surgical situation. Early and accurate diagnosis is critical to provide the necessary aggressive treatment. Conclusion. This clinical observation demonstrates the importance of conducting a study using computed tomography and ultrasound in patients with necrotizing fasciitis for the earliest possible diagnosis and immediate surgical treatment, supported by effective antibiotic therapy.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89508809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Нepatoblastoma in young children 在幼儿中Нepatoblastoma

中国实用医药 Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-1-63-68

I. N. Cherezova, N. Gabitova, I. V. Osipova

引用次数: 0

Substantiation of interval hypoxic therapy for autoimmune thyroiditis treatment in women 间歇缺氧治疗对女性自身免疫性甲状腺炎治疗的证实

中国实用医药 Pub Date : 2023-01-01 DOI: 10.32000/2072-1757-2023-2-68-72

G. A. Ignatenko, E. Maylyan, A. Dubovaya, A. Kaluga, A. N. Goncharov, E. A. Subbotina

{"title":"Substantiation of interval hypoxic therapy for autoimmune thyroiditis treatment in women","authors":"G. A. Ignatenko, E. Maylyan, A. Dubovaya, A. Kaluga, A. N. Goncharov, E. A. Subbotina","doi":"10.32000/2072-1757-2023-2-68-72","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-2-68-72","url":null,"abstract":"The purpose of the study was to evaluate the effects of interval hypoxic therapy in women with autoimmune thyroiditis (AIT) and hypothyroidism. Material and methods. 136 women with newly diagnosed AIT and hypothyroidism were examined and divided into two equal groups. The first group received hormonal replacement therapy with levothyroxine sodium for 12 months. The second group received levothyroxine sodium in combination with interval hypoxic therapy. Results. Levothyroxine sodium therapy in women with newly diagnosed AIT and hypothyroidism was associated with a further increase in the thyroperoxidase autoantibodies blood serum content (p < 0.001). The combination with hypoxic therapy led to the lower autoantibodies values than levothyroxine sodium monotherapy (p < 0.05). In addition, therapy with levothyroxine sodium was characterized by an increased need for medications (p < 0.001). Hypoxic therapy supplementation in AIT provided the medication dose stabilization. Conclusions. It is appropriate to combine levothyroxine sodium with normobaric hypoxic therapy sessions (every 3 months for 10 days) in order to improve the effectiveness of autoimmune thyroiditis and hypothyroidism treatment in women.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"223 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80024654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1