Нepatoblastoma in young children

Abstract

Hepatoblastoma is a common primary malignant tumor in children aged 0 to 4 years. In the structure of liver neoplasms, the pathology occupies 80% and has been steadily growing over the past 30 years with an annual increase of 4–5%. Risk factors for the development of hepatoblastoma include an increase in the survival rate of deeply premature babies, oxidative tissue damage associated with intensive therapy of low birth weight premature babies, and IVF. The disease has no specific complaints and characteristic clinical manifestations. The initial manifestations of hepatoblastoma are often hidden under a variety of mask diseases. It is accompanied by the absence of «oncological alertness» of local pediatricians, which determines the late diagnosis of the liver malignant neoplasm. The article presents an analysis of hepatoblastoma cases in young children over a ten-year period. The main initial clinical manifestations of the disease in early children are indicated. The effectiveness of modern methods of diagnosis and therapy of the liver malignant neoplasms in children is shown. A clinical example of successful treatment of this disease is given.