中国实用医药最新文献

{"title":"Feto-maternal microchimerism: a cause of preeclampsia? The role of trophoblast in the prognosis of pregnancy complicated by preeclampsia","authors":"A. Khasanov, A. V. Arzamastseva, I. Raginov","doi":"10.32000/2072-1757-2023-3-29-35","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-29-35","url":null,"abstract":"Preeclampsia is one of the most important problems in obstetrics. Every year, preeclampsia affects 6–8% of pregnant women in developed countries and over 20% pregnant women in developing countries. It is noted that together with obstetric bleeding and infectious complications, preeclampsia constitutes the so-called «deadly triad» and is the cause of the overwhelming number of maternal deaths. The possibilities of treating preeclampsia are limited only to symptomatic therapy, and in the absence of the desired effect, the patient is offered delivery. To date, new, pathogenetically determined, methods of treatment aimed at inhibiting the activity of membrane-attacking molecules are being considered. This literature review provides information on the role of the trophoblast in the pathogenesis of preeclampsia. The increase in the concentration of trophoblast cells in the mother’s blood leads to excessive activation of the complement system, which causes multiple endothelial damage, leading to multiple organ failure.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83839270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interrelation between the structural-functional condition of myocardium and the activity of vascular-endothelial growth factor and blood inflammatory reaction in patients with pulmonary tuberculosis","authors":"D. Kolchin, V. Ruzov, L. N. Savonenkova","doi":"10.32000/2072-1757-2022-3-2-85-90","DOIUrl":"https://doi.org/10.32000/2072-1757-2022-3-2-85-90","url":null,"abstract":"Taking into account the conflicting literature data on the frequency of the clinical form of pulmonary tuberculosis and its impact on the structural and functional state of the heart, an echocardiographic assessment of heart parameters was carried out in patients with pulmonary tuberculosis and its relationship with the vascular endothelial growth factor VEGF-A. The purpose — to evaluate the relationship between the structural and functional state of the myocardium and the concentration of VEGF in the blood serum in patients with pulmonary tuberculosis. Material and methods. The study included 77 patients with newly diagnosed pulmonary tuberculosis. During the study, the patients were randomized into 3 groups: group 1 — patients with an infiltrative form (n = 42), group 2 — patients with a disseminated form (n = 20), group 3 — patients with fibrous-cavernous form of pulmonary tuberculosis (n = 15). The control group consisted of 10 volunteers. B-mode echocardiography was performed and VEGF concentration was assessed by ELISA. Results. Higher values of RV length, LA area and RA area, and mean LA pressure were found in patients with fibrous-cavernous form, which is due to hypertrophy of the right heart, as indicated by higher values of wall thickness RV — 4.12 mm vs 3.70 in patients of the control group. A high concentration of VEGF-A in the blood serum is associated with higher parameters of erythrocyte sedimentation rate and platelet count, which may indicate a more pronounced systemic inflammatory response in the infiltrative form of pulmonary tuberculosis. Conclusion. Pulmonary tuberculosis is accompanied by structural and functional remodeling of the right and left parts of the heart, the severity of which is associated with the clinical form of the disease. The infiltrative form of pulmonary tuberculosis is associated with significantly higher values of the pro-inflammatory angiogenic cytokine VEGF-A compared to other clinical forms of tuberculosis and the control group.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83041213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical treatment of neovaginal prolapse in a patient with Mayer — Rokitansky — Kuster — Hauser syndrome (clinical case)","authors":"E. R. Mekhtieva, A. G. Yashchuk, I. Musin, E. Popova, A. G. Imelbayeva, A. Tyurina","doi":"10.32000/2072-1757-2023-1-96-98","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-1-96-98","url":null,"abstract":"The article describes a case of complications after surgical treatment of a patient with Mayer — Rokitansky — Kuster — Hauser syndrome, which is characterized by underdevelopment of the Muller ducts derivatives in girls and is manifested by malformations of the vagina and uterus. The features of the diagnosis and surgical treatment of complications using the latest endoscopic techniques are also described.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89134711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical case of combined post-COVID syndrome in a child","authors":"A. Sabitova, I. V. Sitdikova, V. Anokhin, G. R. Fatkullina, G. Kamasheva, V. M. Timasheva","doi":"10.32000/2072-1757-2023-2-115-120","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-2-115-120","url":null,"abstract":"Despite the fact that the new coronavirus infection in children proceeds much milder than in adults, the pediatric practice is facing a problem associated with the general concept of «post-COVID conditions», including Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19 and a complex of disease processes with various manifestations, united by the concept of postacute consequences of treatment or hospitalization for SARS-CoV-2 infection (PASC). The article describes a clinical case of combined post-COVID syndrome, in the form of a MIS-C and the subsequent development of PASC in the form of long-term recurrent urticarial rash elements in a 10-year-old child, simulating reactions similar to serum sickness and chronic urticaria.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76949828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To the 105th anniversary of Kazan school of traumatologists-orthopedists. Transosseous compression-distraction osteosynthesis. Continuing traditions","authors":"I. Pankov, S. D. Sirazitdinov, A. Emelin","doi":"10.32000/2072-1757-2023-3-9-17","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-9-17","url":null,"abstract":"The article presents a brief historical sketch of developing the method of transosseous compression-distraction osteosynthesis in Kazan school of traumatologists-orthopedists. The historical roots of Kazan school of traumatologists-orthopedists are shown. Succession of traditions in the work of the School founders is marked. The stages of improving the method of transosseous compression-distraction osteosynthesis are described by the example the works by doctors and researchers of Kazan Scientific-research Institute for traumatology and orthopedics and its successor — Scientific-practical center for trauma at Republic Clinical Hospital.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"148 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79365852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute coronary syndrome in patients with aortic valve stenosis","authors":"M. Mukanova, F. Kopylov, R. Komarov, I. I. Serebrennikov, F. S. Gafurov, A. N. Khuziakhmedov, N. Babakulova, A. Ismailbaev","doi":"10.32000/2072-1757-2023-2-73-78","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-2-73-78","url":null,"abstract":"The purpose — to assess the acute coronary syndrome (ACS) clinical aspects in patients with aortic stenosis. Material and methods. This is a retrospective single-center study that included comparison of hospital and midterm outcomes of ACS and aortic stenosis (n = 95, divided into the following groups: group 1 — severe aortic stenosis + ACS (n = 39); group 2 — moderate aortic stenosis + ACS (n = 28); group 3 — ACS without aortic stenosis (the control group selected using «Propensity matching» method) (n = 28)). Results. Hospital mortality did not differ statistically between the groups. In group 1, there was a tendency to worse survival within 1 year. In groups with aortic malformation, ACS with ST segment elevation was less common — p = 0.0002 and p = 0.001, respectively. In group 1, 23.1% of patients had intact coronary arteries. Conclusions. Severe aortic valve stenosis in some cases «mimics» acute coronary syndrome, which is indicated by significantly more frequent detection of intact coronary arteries in this cohort. Aortic stenosis of varying degrees does not lead to an increase in the frequency of early postoperative complications and 30-day mortality after PCI.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79431460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On the terms of restoration of finger flexors’ tendons after injury with a profiled metal sheet","authors":"R. Mullin, R. T. Radkov, D. S. Eflova","doi":"10.32000/2072-1757-2023-3-41-44","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-41-44","url":null,"abstract":"The purpose — clinical assessment of the algorithm of terms of the restoration of the finger tendons’ flexor after an injury with a profiled metal sheet. Results. Based on the study results, an algorithm for restorative operations on tendons after an injury with a profiled metal sheet was proposed. When the skin-tendon flap width-to-length ratio is 1:3 or more, one-stage reconstruction of the deep flexor tendon is possible. If the flap width-to-length ratio is less than 1:3, it is necessary to conduct a primary delayed (in 7–10 days) or staged reconstruction of the deep flexor tendon with skin restoration. Conclusion. The presented graphical model of «profiled metal sheet injury» allows giving a clinical assessment of the blood supply to the skin-tendon flap and differentiating treatment of patients with varying degrees of injury severity. In turn, the restoration of normal blood circulation in the injured segment accelerates the healing process, reduces the percentage of complications, and ultimately determines the success of the surgical intervention.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79404491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contribution of the scientific, medical and public activity of Viktor Konstantinovich Menshikov into the development of Russian pediatrics","authors":"O. I. Pikuza, S. V. Maltsev, A. M. Zakirova, F. Rizvanova, E. Generalova","doi":"10.32000/2072-1757-2023-4-143-148","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-4-143-148","url":null,"abstract":"The article reflects the diverse activity of Prof. V.K. Menshikov as a clinician, a pedagogue, and a researcher. Detailed information is presented about the formation, based on a Kazan children’s hospital, of a new direction in rendering medical assistance to babies and in nutrition science; the contribution of Prof. V.K. Menshikov into training of medical and scientific staff in TASSR and far beyond is shown.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83984429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Features of treatment of the combined functional disorders of gastrointestinal tract in patients who had a new coronavirus infection on an outpatient basis","authors":"M. S. Turchinа, M. V. Bukreeva, Zh. E. Annenkova, Yu. M. Morozov, T. I. Obolenskaya","doi":"10.32000/2072-1757-2023-1-38-41","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-1-38-41","url":null,"abstract":"Patients with COVID-19 often suffer from a variety of gastrointestinal disorders. Often this is directly related to the effect of the virus on the epithelial cells of the gastrointestinal tract, as well as the prescription of drugs for the new coronavirus infection treatment. In some patients, gastrointestinal disturbances precede the onset of respiratory symptoms and remain for a long time after recovery, significantly reducing the quality of life. Approximately every second patient who had a COVID-19 infection suffers from stool disorders and dyspeptic symptoms. The most common variant of post-covid lesions of the gastrointestinal tract is functional dyspepsia and irritable bowel syndrome, which outpatient doctors have recently encountered more and more often. In most cases, the attending physician pays more attention to the pulmonary and cardiological manifestations of coronavirus infection, while the symptoms of gastrointestinal lesions are considered minor. The purpose of this article — is to consider possible methods for correcting the functional pathology of the gastrointestinal tract in patients after a COVID-19 infection.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75809615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treating chronic instability of the acromioclavicular joint","authors":"R. Salikhov, M. Chekunov, O. Teplov, D. Galimov, V. Solovyev","doi":"10.32000/2072-1757-2023-3-23-28","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-23-28","url":null,"abstract":"The acromioclavicular joint is the link between the collarbone and the scapula, responsible for synchronizing movements in the upper shoulder girdle. Chronic instability of the acromioclavicular joint leads to changes in the orientation of the scapula, which provokes kinematic disorders leading to chronic pain. In case of acute dislocation of the acromial end of the clavicle, minimally invasive techniques are usually used, such as fixation with spokes or a hook-shaped plate, or arthroscopic fixation. Surgical techniques for the treatment of patients with acromioclavicular joint chronic symptomatic instability differ significantly from those used to treat patients with acute dislocation of the acromioclavicular joint. In this case, reconstruction of torn ligaments is necessary, because the biological potential of restoring these structures is exhausted after 3–4 weeks. The range of possibilities includes anatomical and non-anatomical techniques, open and minimally invasive procedures using arthroscopy, as well as biological and synthetic transplants. This article presents the authors’ approach to treating such patients and describes the modern reliable surgical technique.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83306783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}