中国实用医药最新文献

{"title":"Interrelation between the structural-functional condition of myocardium and the activity of vascular-endothelial growth factor and blood inflammatory reaction in patients with pulmonary tuberculosis","authors":"D. Kolchin, V. Ruzov, L. N. Savonenkova","doi":"10.32000/2072-1757-2022-3-2-85-90","DOIUrl":"https://doi.org/10.32000/2072-1757-2022-3-2-85-90","url":null,"abstract":"Taking into account the conflicting literature data on the frequency of the clinical form of pulmonary tuberculosis and its impact on the structural and functional state of the heart, an echocardiographic assessment of heart parameters was carried out in patients with pulmonary tuberculosis and its relationship with the vascular endothelial growth factor VEGF-A. The purpose — to evaluate the relationship between the structural and functional state of the myocardium and the concentration of VEGF in the blood serum in patients with pulmonary tuberculosis. Material and methods. The study included 77 patients with newly diagnosed pulmonary tuberculosis. During the study, the patients were randomized into 3 groups: group 1 — patients with an infiltrative form (n = 42), group 2 — patients with a disseminated form (n = 20), group 3 — patients with fibrous-cavernous form of pulmonary tuberculosis (n = 15). The control group consisted of 10 volunteers. B-mode echocardiography was performed and VEGF concentration was assessed by ELISA. Results. Higher values of RV length, LA area and RA area, and mean LA pressure were found in patients with fibrous-cavernous form, which is due to hypertrophy of the right heart, as indicated by higher values of wall thickness RV — 4.12 mm vs 3.70 in patients of the control group. A high concentration of VEGF-A in the blood serum is associated with higher parameters of erythrocyte sedimentation rate and platelet count, which may indicate a more pronounced systemic inflammatory response in the infiltrative form of pulmonary tuberculosis. Conclusion. Pulmonary tuberculosis is accompanied by structural and functional remodeling of the right and left parts of the heart, the severity of which is associated with the clinical form of the disease. The infiltrative form of pulmonary tuberculosis is associated with significantly higher values of the pro-inflammatory angiogenic cytokine VEGF-A compared to other clinical forms of tuberculosis and the control group.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83041213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stress echocardiography in the diagnosis of cardiac dysfunction in the early post-infarction period","authors":"A. M. Vorobev, V. Ruzov, M. A. Melnikova, V. A. Kadebina","doi":"10.32000/2072-1757-2023-4-102-107","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-4-102-107","url":null,"abstract":"The purpose — to assess the importance of stress echocardiography in identifying the nature and severity of cardiac dysfunction in patients with myocardial infarction. Material and methods.86 patients were examined at the outpatient stage of rehabilitation 6 weeks after myocardial infarction with primary coronary angioplasty with stenting. Results.Echocardiography revealed left ventricular hypertrophy (LVH) in 34 patients with myocardial infarction with concomitant arterial hypertension. Patients with LVH are characterized by more pronounced structural and functional LV remodeling, which is expressed in a lower LVEF and increased LVEDD, LVESVand LVEDV(p<0.05). There were no differences in stroke volume between patients with and without LVH. The performed diastolic stress test in patients with LVH is characterized by significantly lower average early diastolic mitral annular velocity e` (7.6 vs. 9.3 cm/s, p<0.01) without differences in the peak early transmitral Doppler flow velocity E (69.8 vs 78.0, p>0.05) compared with patients without LVH. The revealed differences between patients with and without LVH are due to a higher post-exercise velocity e` in patients with normal LV geometry and a decrease in eccentric LVH subgroup. Conclusions.1) Patients with LVH in the early postinfarction period (6 weeks) have more pronounced LV systolic dysfunction, expressed in a decrease in LVEF and an increase in LVEDD, LVESV, LVEDV compared to patients without LVH.2) Left ventricular hypertrophy, in conditions of myocardial infarction, is associated with latent diastolic dysfunction, which is manifested by a lower average early diastolic mitral annular velocity e` after the stress-test.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83780339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feto-maternal microchimerism: a cause of preeclampsia? The role of trophoblast in the prognosis of pregnancy complicated by preeclampsia","authors":"A. Khasanov, A. V. Arzamastseva, I. Raginov","doi":"10.32000/2072-1757-2023-3-29-35","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-29-35","url":null,"abstract":"Preeclampsia is one of the most important problems in obstetrics. Every year, preeclampsia affects 6–8% of pregnant women in developed countries and over 20% pregnant women in developing countries. It is noted that together with obstetric bleeding and infectious complications, preeclampsia constitutes the so-called «deadly triad» and is the cause of the overwhelming number of maternal deaths. The possibilities of treating preeclampsia are limited only to symptomatic therapy, and in the absence of the desired effect, the patient is offered delivery. To date, new, pathogenetically determined, methods of treatment aimed at inhibiting the activity of membrane-attacking molecules are being considered. This literature review provides information on the role of the trophoblast in the pathogenesis of preeclampsia. The increase in the concentration of trophoblast cells in the mother’s blood leads to excessive activation of the complement system, which causes multiple endothelial damage, leading to multiple organ failure.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83839270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adenomyosis and endometriosis: common features","authors":"R. Gabidullina, F. F. Minnullina, T. N. Shigabutdinova, D. I. Akhmetova, A. Zaripova, S. I. Kharitonova","doi":"10.32000/2072-1757-2023-4-37-40","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-4-37-40","url":null,"abstract":"The purpose — to summarize the results of molecular genetic studies of adenomyosis and endometriosis. Material and methods. Review of publications based on search results in the electronic resources PubMed, Elibrary, EMBASE and Google Scholar. Results. Marked differences between endometriosis and adenomyosis in pathogenesis, lesion localisation and clinical features have led to the recognition of adenomyosis as a separate clinical entity. In the new International Classification of Diseases 11th Revision, adenomyosis was removed from the section «Endometriosis» (GA10) and presented as a separate disease «Adenomyosis». Identical KRAS mutations in epithelial cells in endometriosis, adenomyosis and combined endometriosis suggest that adenomyosis and endometriosis are oligoclonal lesions arising from populations of cells of the basal layer of the endometrium carrying a specific driver mutation. Medication strategies that block ovarian steroidogenesis, as well as local estrogen synthesis, are a long-term treatment option for these chronic diseases. Conclusion. The results of molecular genetic studies indicate that endometriosis and adenomyosis are related conditions with a common molecular etiology.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84073944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"History of the development of the hemodialysis service in the Republic of Tatarstan","authors":"N. R. Gatiyatullin, A. Maksudova, M. Khasanova, M. D. Trofimova","doi":"10.32000/2072-1757-2023-3-8-13","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-8-13","url":null,"abstract":"The article provides information on the formation of hemodialysis service in the Republic of Tatarstan, starting from the first Russian «artificial kidney» model, the first arterio-venous shunt and dialyzer to the present day.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88315184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical treatment of neovaginal prolapse in a patient with Mayer — Rokitansky — Kuster — Hauser syndrome (clinical case)","authors":"E. R. Mekhtieva, A. G. Yashchuk, I. Musin, E. Popova, A. G. Imelbayeva, A. Tyurina","doi":"10.32000/2072-1757-2023-1-96-98","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-1-96-98","url":null,"abstract":"The article describes a case of complications after surgical treatment of a patient with Mayer — Rokitansky — Kuster — Hauser syndrome, which is characterized by underdevelopment of the Muller ducts derivatives in girls and is manifested by malformations of the vagina and uterus. The features of the diagnosis and surgical treatment of complications using the latest endoscopic techniques are also described.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89134711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical case of infliximab induction in a patient with Crohn’s disease and acute new coronavirus infection","authors":"D. Mukhametova, E. Bodryagina, A. Odintsova, L. Kupkenova, D. F. Shafikova, B. M. Fontenelle, D. Abdulganieva","doi":"10.32000/2072-1757-2023-3-121-124","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-121-124","url":null,"abstract":"The article presents a clinical case of a new coronavirus infection in a patient with CD. The onset of the viral infection occurred during severe exacerbation of CD, what led to induction of infliximab therapy. The difficulty of managing patients with COVID-19 and immunoinflammatory diseases is discussed.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86255648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deventer’s pelvis, «gate of life» and the aggressive management of childbirth at the present time. Сlinical observation","authors":"A. Khasanov, F. F. Minullina","doi":"10.32000/2072-1757-2023-3-75-79","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-75-79","url":null,"abstract":"In modern obstetrics, aggressive technologies are often used in the management of childbirth, the harm of which was mentioned by Hendrik van Deventer. The founder of classical obstetrics, born in Holland in 1651 and working during the epoch of obstetrics renaissance, Deventer wrote eight books popular till today. Deventer was an active opponent of aggressive obstetrics — he did not use obstetric forceps, nor the vacuum extraction of the fetus that was emerging at that time. He was the first to give a detailed description of the pelvis and to suggest that the shape and size of the pelvic bone could cause difficulties in childbirth. His instructions — to change the position of a woman in labor with pathological insertions of the fetal head are widely used by modern obstetricians. The term «Deventer’s pelvis» went down in the history of obstetrics – a simple flat pelvis, in which all direct dimensions are reduced (the planes of the entrance, cavity and exit of the pelvis). One of the varieties of Deventer’s pelvis is a reduction of only the direct size of the wide part of the pelvic cavity (with all other normal pelvic sizes), which occurs in 15–18% of all pregnant women. The presented clinical observation shows how the use of the Kristeller’s technique with a delayed fetal head can lead to severe traumatic complications in both the mother and the fetus. The authors recommend measuring the pubic-sacral size, which shows the size of the sacral cavity, to all pregnant women.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81410371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consequences of accidental intra-arterial administration of bicillin — Hoigne syndrome","authors":"A. Z. Nigmedzyanova, L. Kulagina, E. R. Kadyseva, R. V. Davletshina","doi":"10.32000/2072-1757-2023-3-130-133","DOIUrl":"https://doi.org/10.32000/2072-1757-2023-3-130-133","url":null,"abstract":"The article presents a description of a rare clinical case of consequences of accidental intra-arterial administration of bicillin with the development of Hoigne syndrome.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79161125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combination of congenital malformation of the gastrointestinal tract and kidneys: a clinical case","authors":"S. V. Aborin, D. V. Pechkurov, A. V. Varlamov, A. V. Maznova, N. V. Sviridova","doi":"10.32000/2072-1757-2022-4-123-125","DOIUrl":"https://doi.org/10.32000/2072-1757-2022-4-123-125","url":null,"abstract":"Currently, the correction of congenital malformations in children is one of the important tasks of modern medicine. If a radical correction of the defect is performed timely, the child will grow up healthy. Combinations of congenital malformations create serious difficulties for clinicians and require the participation of a multidisciplinary team, combining various approaches and methods. The article presents a clinical case of a newborn child with atresia of the ileum, hypoplasia of the aortic arch and bilateral hypoplasia of the kidneys. Since birth, the child’s condition was complicated by the development of shock and subsequent azotemia, hyperhydration. Since the correction of atresia could not be postponed for a long time, it was decided to perform implantation of a peritoneal catheter during surgery on the intestine in case of a repeat episode of acute kidney injury. The presented clinical case demonstrates the possibility of renal replacement therapy in patients after surgery in the abdominal cavity.","PeriodicalId":9821,"journal":{"name":"中国实用医药","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75553429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}