Organic Chemistry Frontiers最新文献_第8页

Modular synthesis of 2-arylpyridines metal free-four component [2 + 2 + 1 + 1] annulation 金属游离2-芳基吡啶的模块化合成[2 + 2 + 1 + 1]环

IF 5.4 1区化学

Organic Chemistry Frontiers Pub Date : 2026-09-16 DOI: 10.1039/d6qo00829a

Yanfeng Ma,Rong Huang,Fuhong Xiao,Guo-Jun Deng

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Skeletal editing of anthranils O-to-CN transmutation: access to ring-expanded quinazolines 蒽酚O-to-CN突变的骨架编辑：获得扩环喹唑啉

IF 5.4 1区化学

Organic Chemistry Frontiers Pub Date : 2026-09-16 DOI: 10.1039/d6qo00702c

Yongzhen Li,Zicheng Liao,Lijuan Zhou,Jiajin Luo,Saihui Song,Shuo-Wen Wang,Shi Tang

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Sustainable metal- and base-free acylative Suzuki-type cross-coupling of carboxylic acids and boronic acids 羧酸和硼酸的可持续无金属和无碱酰化铃木型交叉偶联

IF 5.4 1区化学

Organic Chemistry Frontiers Pub Date : 2026-09-16 DOI: 10.1039/d6qo00799f

Shuaichen Zhang,Mengdie Zhang,Jing Zhang,Cheng Wang,Yujie Li,Shang Gao,Aijun Lin,Peng Sun

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From nature to synthetic analogues: recent advances in the design and synthesis of natural product-based libraries 从自然到合成类似物：基于自然产物的库的设计和合成的最新进展

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Organic Chemistry Frontiers Pub Date : 2026-09-16 DOI: 10.1039/d6qo00727a

Iván Cheng-Sánchez,Irama Fuentes-Pino,Mohamed El Hllafi,Federico Moya-Utrera,J. Manuel López-Romero,Amelia Díaz-Morilla,Antonio Sánchez-Ruiz,Michio Kurosu,Francisco Sarabia

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Synthesis of 3-formyl-6-azaindoles Vilsmeier–Haack formylation of 3-amino-4-methyl pyridines 3-氨基-4-甲基吡啶的Vilsmeier-Haack甲酰化合成

IF 5.4 1区化学

Organic Chemistry Frontiers Pub Date : 2026-09-16 DOI: 10.1039/d6qo00452k

Sergey P. Ivonin,Volodymyr V. Voloshchuk,Diana S. Stepanova,Svetlana V. Shishkina,Serhiy V. Ryabukhin,Dmytro M. Volochnyuk

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Ambient and aerobic C–N bond cleavage toward α-ketoester synthesis through LMCT excitation of CeCl 通过LMCT激发CeCl合成α-酮酯的环境和需氧C-N键裂解

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Organic Chemistry Frontiers Pub Date : 2026-09-16 DOI: 10.1039/d6qo00851h

Jiabin Shen,Yezhe Zhao,Xiangbo Ma,Liangfeng Yang,Hao Xu,Chao Shen

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Nucleophile-controlled divergent synthesis: photocatalyzed carboamination of allenes 亲核控制的发散合成：烯的光催化碳胺化

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Organic Chemistry Frontiers Pub Date : 2026-09-16 DOI: 10.1039/d6qo00656f

Suyu Ji,Zhiguo Zhang,Zhibin Sun,Kui Xue,Rupu Zhao,Xinrui Wang,Guisheng Zhang,Guangyue Bai

{"title":"Nucleophile-controlled divergent synthesis: photocatalyzed carboamination of allenes","authors":"Suyu Ji,Zhiguo Zhang,Zhibin Sun,Kui Xue,Rupu Zhao,Xinrui Wang,Guisheng Zhang,Guangyue Bai","doi":"10.1039/d6qo00656f","DOIUrl":"https://doi.org/10.1039/d6qo00656f","url":null,"abstract":"Controllable synthesis strategies provide an efficient and straightforward approach for the rapid construction of structurally diverse functional organic molecular frameworks from a single class of starting materials. The photo-induced radical addition of difluorobromides to allenes represents such a promising strategy. Herein, we demonstrate that following the radical addition of bromodifluoroacetamides to allenes, the newly formed radical intermediates can be oxidized to carbocations, which are subsequently attacked by amine nucleophiles to afford cyclic γ-lactams or linear amides bearing both fluorine and alkenyl moieties. Facilitated by visible light and iodide ions, this radical addition reaction occurs regiospecifically at the 1 and 2 positions of the allene compounds, and no addition products at other positions or nucleophilic adducts with mixed amine regioisomers are observed. This reaction features broad substrate scope, exceptional functional group tolerance, and facile post-functionalization, delivering fluorine-containing products with important biological and functional properties. Thus, this methodology exhibits promising application potential in materials science, agrochemistry, and medicinal chemistry.","PeriodicalId":97,"journal":{"name":"Organic Chemistry Frontiers","volume":"54 1","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148973543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Biomimetic asymmetric total syntheses of myrtucommulone J and myrtucyclitones A–D with anti-leukemic activity 具有抗白血病活性的桃金娘素酮J和桃金娘环酮A-D的仿生不对称全合成

IF 5.4 1区化学

Organic Chemistry Frontiers Pub Date : 2026-09-16 DOI: 10.1039/d6qo00786d

Yan-Yi Wu,Shi-Lin Lin,Shanshan Song,Chao Yang,Xulin Han,Mei-Qi Zheng,Yanli Jin,Wen-Jing Wang,Chuang-Chuang Li,Chang Liu,Lei Wang,Wen-Cai Ye,Min-Jing Cheng

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The synthesis and isolation of three states of naphthalene dianhydride: radical ion, red-emissive and electron-rich zwitterion, and highly electron-deficient switchable states 二氢化萘三态的合成与分离：自由基离子、红发富电子两性离子、高缺电子可切换态

IF 5.4 1区化学

Organic Chemistry Frontiers Pub Date : 2026-09-16 DOI: 10.1039/d6qo00457a

Sonam Chorol,Sharvan Kumar,Ch Mudasar Hussain,M. S. Krishna Kumar,Suvendu Dey,Pritam Mukhopadhyay

{"title":"The synthesis and isolation of three states of naphthalene dianhydride: radical ion, red-emissive and electron-rich zwitterion, and highly electron-deficient switchable states","authors":"Sonam Chorol,Sharvan Kumar,Ch Mudasar Hussain,M. S. Krishna Kumar,Suvendu Dey,Pritam Mukhopadhyay","doi":"10.1039/d6qo00457a","DOIUrl":"https://doi.org/10.1039/d6qo00457a","url":null,"abstract":"Radical ions with reactive functional groups are challenging to isolate, but isolation along with their redox congeners can lead to the origination of intriguing opto-electronic features, novel supramolecular facets, and the realization of uncharted redox potentials. π-Conjugated anhydrides are yet to be stabilized and isolated in pure radical form, and their other redox states are yet to be isolated and investigated. Herein, we report the ambient isolation of a dianhydride radical ion (1˙+), its 2e−-reduced and electron-rich zwitterionic form (12±), and an extremely electron-deficient dication (12+) in three distinctly colored crystalline states. Notably, compared to reported diimide-based systems, the dianhydride radical ion exhibits red-shifted bands extending to the NIR region. Likewise, the doubly reduced dianhydride zwitterionic state also shows red-shifted absorption bands compared to direduced NDIs. The zwitterionic state also shows red emission extending to the NIR region. The zwitterionic state manifests a high HOMO energy level corresponding to −4.64 eV, which is comparable to the seminal e−-donor tetrathiafulvalene (TTF). The highly electron-deficient dicationic dianhydride exhibits exceptionally strong electron deficiency, superior to reported diimides, with a remarkably low electrochemically estimated LUMO energy of ∼−5.07 eV. Finally, we realized 2e− redox-driven aromaticity switching in the naphthalene rings of the zwitterion ↔ dication states. Such bottleable, crystalline multi-states with reactive functional groups can enable the expansion of the existing library of switchable open-/closed-shell states.","PeriodicalId":97,"journal":{"name":"Organic Chemistry Frontiers","volume":"144 1","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148973564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Pyrene-based photoresponsive materials: beyond luminescence 比利牛斯基光响应材料：超越发光

IF 5.4 1区化学

Organic Chemistry Frontiers Pub Date : 2026-09-16 DOI: 10.1039/d6qo00640j

Junying Zhang,Xing-Dong Xu

{"title":"Pyrene-based photoresponsive materials: beyond luminescence","authors":"Junying Zhang,Xing-Dong Xu","doi":"10.1039/d6qo00640j","DOIUrl":"https://doi.org/10.1039/d6qo00640j","url":null,"abstract":"As an important class of stimuli-responsive luminescent materials, photoresponsive pyrene-based fluorescent materials exhibit broad application prospects in fields such as intelligent sensing, information encryption, biomedicine, and flexible electronics due to their unique photophysical properties, tunable aggregation behavior, and high sensitivity to external light stimuli. This article systematically reviews the research progress of photoresponsive pyrene-based fluorescent materials in recent years, focusing on four types of photoresponsive mechanisms: photodecomposition, photopolymerization, photoisomerization, and other composite response systems. It elaborates on the design strategies, photoresponsive behaviors, and applications of various materials in controlled drug release, information storage, circularly polarized luminescence, cell imaging, and self-healing materials. The article further summarizes the current challenges faced in this field, including molecular structure–activity relationships, response speed, cycling stability, and large-scale preparation. It also outlines future directions for development, such as guiding molecular design through theoretical calculations, developing near-infrared response systems, and expanding biomedical and information security applications. The aim is to provide references for the rational design and application innovation of high-performance pyrene-based photoresponsive materials.","PeriodicalId":97,"journal":{"name":"Organic Chemistry Frontiers","volume":"4 1","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148973532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0