Central European Journal of Urology最新文献

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Balancing technology and resources: Is robotic pyeloplasty always necessary? 平衡技术和资源:机器人肾盂成形术总是必要的吗?
IF 1.9
Central European Journal of Urology Pub Date : 2025-01-01 Epub Date: 2025-04-30 DOI: 10.5173/ceju.2024.0203
Kunal Malhotra, Vikas Kumar Panwar, Gautam Shubhankar, Ankur Mittal, Mohammed Taher Mujahid
{"title":"Balancing technology and resources: Is robotic pyeloplasty always necessary?","authors":"Kunal Malhotra, Vikas Kumar Panwar, Gautam Shubhankar, Ankur Mittal, Mohammed Taher Mujahid","doi":"10.5173/ceju.2024.0203","DOIUrl":"10.5173/ceju.2024.0203","url":null,"abstract":"<p><strong>Introduction: </strong>Ureteropelvic junction obstruction (UPJO) hinders urine flow from the renal pelvis to the ureter, causing renal dysfunction. Treatment focuses on relieving obstruction to restore urinary drainage and preserve renal function. Robotic-assisted laparoscopic pyeloplasty (RALP) offers enhanced precision compared to laparoscopic pyeloplasty (LP), but limited comparative data exist for adult patients. This study compares RALP and LP outcomes in an adult cohort from a tertiary care centre.</p><p><strong>Material and methods: </strong>A retrospective cohort analysis was conducted on adult patients who underwent RALP or LP between March 2018 and May 2024. Primary outcome measures included operative time, with secondary outcomes such as estimated blood loss (EBL), hospital length of stay (LOS), complication rates, and success (defined by symptom relief and diuretic renogram improvement). Statistical analysis included Mann-Whitney, χ<sup>2</sup>, and Fisher's exact tests, with a significance threshold of p <0.05.</p><p><strong>Results: </strong>The study included 128 patients (87 RALP, 41 LP). Operative time was significantly longer for RALP (200.92 ±59.26 minutes) vs LP (161.92 ±55.21 minutes, p <0.001), largely due to robotic docking. Both groups had similar EBL (47.87 ml for RALP vs 45 ml for LP, p = 0.45) and success rates (97.7% for RALP vs 97.4% for LP). However, RALP patients experienced a longer LOS (3.91 days vs 3.41 days, p = 0.001).</p><p><strong>Conclusions: </strong>RALP demonstrates technical advantages but does not reduce operative time and incurs increased resource utilisation compared to LP. Both techniques achieve high success rates, though further research is needed to assess RALP's cost-effectiveness.</p>","PeriodicalId":9744,"journal":{"name":"Central European Journal of Urology","volume":"78 2","pages":"244-249"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379814/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complications of anatomical endoscopic enucleation of the prostate in real-life practice: What we learnt from the 6,193 patients from the Refinement in Endoscopic Anatomical enucleation of Prostate registry. 前列腺解剖腔镜摘除在现实生活中的并发症:我们从6193例患者中总结出的改进前列腺解剖腔镜摘除登记的经验。
IF 1.9
Central European Journal of Urology Pub Date : 2025-01-01 Epub Date: 2025-05-16 DOI: 10.5173/ceju.2024.0060
Ee Jean Lim, Thomas R W Herrmann, Daniele Castellani, Khi Yung Fong, Edwin Jonathan Aslim, Sarvajit Biligere, Azimdjon N Tursunkulov, Marco Dellabella, Fernando Gomez Sancha, Mario Sofer, Dmitry Enikeev, Marcelo Langer Wroclawski, Vladislav Petov, Nariman Gadzhiev, Dean Elterman, Abhay Mahajan, Moises Rodriguez Socarras, Dilmurod S Yunusov, Furkat Nasirov, Jeremy Yuen-Chun Teoh, Bhaskar Kumar Somani, Vineet Gauhar
{"title":"Complications of anatomical endoscopic enucleation of the prostate in real-life practice: What we learnt from the 6,193 patients from the Refinement in Endoscopic Anatomical enucleation of Prostate registry.","authors":"Ee Jean Lim, Thomas R W Herrmann, Daniele Castellani, Khi Yung Fong, Edwin Jonathan Aslim, Sarvajit Biligere, Azimdjon N Tursunkulov, Marco Dellabella, Fernando Gomez Sancha, Mario Sofer, Dmitry Enikeev, Marcelo Langer Wroclawski, Vladislav Petov, Nariman Gadzhiev, Dean Elterman, Abhay Mahajan, Moises Rodriguez Socarras, Dilmurod S Yunusov, Furkat Nasirov, Jeremy Yuen-Chun Teoh, Bhaskar Kumar Somani, Vineet Gauhar","doi":"10.5173/ceju.2024.0060","DOIUrl":"10.5173/ceju.2024.0060","url":null,"abstract":"<p><strong>Introduction: </strong>Anatomical endoscopic enucleation of the prostate (AEEP) is a guideline-recommended treatment for benign prostatic hyperplasia (BPH). We aimed to analyze postoperative complications and outcomes within a large real-world database.</p><p><strong>Material and methods: </strong>The Refinement in Endoscopic Anatomical enucleation of Prostate (REAP) registry includes patients who received AEEP for BPH in 8 centers worldwide from January 2020 to January 2022. Exclusion criteria included previous prostate/urethral surgery, prostate cancer, pelvic radiotherapy, and concomitant lower urinary tract surgery (internal urethrotomy, cystolithotripsy, or transurethral resection of bladder tumor). The primary outcome was postoperative incontinence; secondary outcomes included early complications (<30 days) and late complications (>30 days).</p><p><strong>Results: </strong>We analyzed 6,193 patients; the mean age was 68 years. Thulium laser was used in 37% and high-power holmium laser in 32%. Median operation time was 67 min [IQR 50-95 min]. The 2-lobe enucleation technique was utilized in 49%, and en-bloc resection was utilized in 39%. Early postoperative complications included urinary tract infection (4.7%), acute urinary retention (4.1%), post-operative bleeding requiring additional intervention (0.9%), and sepsis requiring intensive care admission (0.1%). The incidence of postoperative incontinence was 14.8%, of which 54% were stress incontinence; 84% cases resolved by 3 months. On univariate and multivariate analysis, prostate volume >100 ml was a significant predictor of postoperative incontinence. Late complications such as bulbar urethral stricture, bladder neck sclerosis, and need for redo BPH surgery each occurred in <1% of patients.</p><p><strong>Conclusions: </strong>Analysis of the real-world REAP database shows favorable safety outcomes for AEEP, with a low incidence of serious complications and postoperative incontinence beyond 3 months.</p>","PeriodicalId":9744,"journal":{"name":"Central European Journal of Urology","volume":"78 2","pages":"137-143"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laser fibers and baskets. How do they affect suction and intrarenal pressures using the novel single-use flexible direct in-scope suction ureteroscopes? 激光纤维和篮子。使用新型的一次性柔性直接镜内吸引输尿管镜,它们如何影响吸引和肾内压力?
IF 1.9
Central European Journal of Urology Pub Date : 2025-01-01 Epub Date: 2025-08-31 DOI: 10.5173/ceju.2025.0120
Arman Tsaturyan, Alberto Olivero, Eugenio Ventimiglia, Arkadya Musayelyan, Hayk Grigoryan, Armen Muradyan, Marat Harutyunyan, Evangelos Liatsikos, Panagiotis Kallidonis, Vineet Gauhar, Steffi Kar Kei Yuen, Olivier Traxer, Bhaskar Somani, Amelia Pietropaolo
{"title":"Laser fibers and baskets. How do they affect suction and intrarenal pressures using the novel single-use flexible direct in-scope suction ureteroscopes?","authors":"Arman Tsaturyan, Alberto Olivero, Eugenio Ventimiglia, Arkadya Musayelyan, Hayk Grigoryan, Armen Muradyan, Marat Harutyunyan, Evangelos Liatsikos, Panagiotis Kallidonis, Vineet Gauhar, Steffi Kar Kei Yuen, Olivier Traxer, Bhaskar Somani, Amelia Pietropaolo","doi":"10.5173/ceju.2025.0120","DOIUrl":"10.5173/ceju.2025.0120","url":null,"abstract":"<p><strong>Introduction: </strong>To evaluate intrarenal pressures (IRP) and suction performance of two novel flexible ureteroscopes equipped with a direct-in-scope suction (DISS) feature - the 7.5 Fr PU3033AH and the 9.2 Fr PU400A - both with an empty working channel and with various working instruments inserted.</p><p><strong>Material and methods: </strong>An <i>ex vivo</i> experimental study was conducted using a freshly harvested porcine kidney. Measurements were performed under the following conditions: empty working channel, with a 200 µm laser fiber, a 272 µm laser fiber, and a 2.2 Fr nitinol basket. The evaluated parameters included: irrigation flow rates with gravity irrigation and an automated pump, maximum IRP without suctioning, time to collapse of the pelvicalyceal system, and time to regain baseline IRP after suctioning.</p><p><strong>Results: </strong>The highest IRP of 34 mmHg was recorded with the 9.2 Fr scope under 100 mmHg irrigation pressure. Irrespective of the irrigation system used, the introduction of working instruments significantly reduced the IRP for both 7.5 Fr and 9.2 Fr DISS scopes. A longer time was required to collapse the pelvicalyceal system and regain the basal intrarenal pressure when working instruments were used. The thicker the diameter of the instrument, the greater the impact on flowrate, IRP, collapse of the system, and regain of the pressure was observed. The latter trends were less pronounced with the 9.2 Fr scope with a wider 5.1 Fr working channel.</p><p><strong>Conclusions: </strong>The 9.2 Fr DISS ureteroscope demonstrated higher irrigation flow rates and IRP, and shorter times to system collapse and recovery compared to the 7.5 Fr scope. However, the insertion of working instruments negatively affected all measured parameters, with a greater impact observed in the 7.5 Fr scope due to its narrower channel.</p>","PeriodicalId":9744,"journal":{"name":"Central European Journal of Urology","volume":"78 3","pages":"406-412"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12663821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145647143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison between single-shot and gradual dilation technique in percutaneous nephrolithotomy: A systematic review and meta-analysis. 经皮肾镜取石术中单次和渐进式扩张技术的比较:系统回顾和荟萃分析。
IF 1.9
Central European Journal of Urology Pub Date : 2025-01-01 Epub Date: 2025-08-31 DOI: 10.5173/ceju.2024.0256
Kharisma Prasetya Adhyatma, Muhammad Ainul Mahfuz, Dianita Halimah Harahap, Muhammad Haritsyah Warli, Fauriski Febrian Prapiska
{"title":"Comparison between single-shot and gradual dilation technique in percutaneous nephrolithotomy: A systematic review and meta-analysis.","authors":"Kharisma Prasetya Adhyatma, Muhammad Ainul Mahfuz, Dianita Halimah Harahap, Muhammad Haritsyah Warli, Fauriski Febrian Prapiska","doi":"10.5173/ceju.2024.0256","DOIUrl":"10.5173/ceju.2024.0256","url":null,"abstract":"<p><strong>Introduction: </strong>Percutaneous nephrolithotomy (PCNL) is efficacious for the management of bigger or complex renal calculi. This study assesses the safety and efficacy of single-shot dilation (one-shot - OD) against gradual dilation (multiple - MD) in fluoroscopy-guided PCNL, with the objective of enhancing stone management techniques.</p><p><strong>Material and methods: </strong>A comprehensive study adhering to PRISMA criteria concentrated on adult patients receiving conventional percutaneous nephrolithotomy for nephrolithiasis. Included were clinical trials and cohort studies comparing OD and MD approaches, but omitting ultrasound-guided, mini, and micro-PCNL methods. Investigations were performed in PubMed, Scopus, EMBASE, Cochrane Library, and Medline from 2008 onwards. Two reviewers independently evaluated and extracted data, employing the Cochrane ROB2 and ROBINS-I instruments for quality evaluation. Statistical analyses utilizing Review Manager 5.4 employed fixed and random-effects models contingent upon heterogeneity (I<sup>2</sup>).</p><p><strong>Results: </strong>Sixteen studies (14 randomized controlled trials and 2 cohort studies) including 572 individuals with OD and 581 patients with MD were examined. The meta-analysis indicated a markedly reduced complication rate in the OD group (RR = 0.77; 95% CI: 0.63-0.94; p = 0.01), with no statistically significant difference in stone-free rates (RR = 1.02; 95% CI: 0.97-1.08; p = 0.49). Variations in hemoglobin reduction, duration of hospitalization, fluoroscopy exposure, and surgical time were noted. However, the significant variability requires cautious interpretation.</p><p><strong>Conclusions: </strong>The single-shot dilation approach showed a markedly reduced complication rate, indicating it as a safer option for adult patients having conventional PCNL. Additional research is required to corroborate these results across various clinical environments.</p>","PeriodicalId":9744,"journal":{"name":"Central European Journal of Urology","volume":"78 3","pages":"373-384"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12663817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145647481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Another step toward a better understanding of urinary drainage after upper tract endoscopy. 进一步了解上尿路内窥镜检查后的尿路引流。
IF 1.9
Central European Journal of Urology Pub Date : 2025-01-01 Epub Date: 2025-05-26 DOI: 10.5173/ceju.2025.0001_EdCom
Jacopo Durante
{"title":"Another step toward a better understanding of urinary drainage after upper tract endoscopy.","authors":"Jacopo Durante","doi":"10.5173/ceju.2025.0001_EdCom","DOIUrl":"10.5173/ceju.2025.0001_EdCom","url":null,"abstract":"","PeriodicalId":9744,"journal":{"name":"Central European Journal of Urology","volume":"78 2","pages":"199"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A cross-language analysis of urolithiasis patient online materials: Assessment across 24 European languages. 尿石症患者在线资料的跨语言分析:跨24种欧洲语言的评估。
IF 1.9
Central European Journal of Urology Pub Date : 2025-01-01 Epub Date: 2025-05-26 DOI: 10.5173/ceju.2025.0045
Wojciech Tomczak, Wojciech Krajewski, Katarzyna Grunwald, Adam Chełmoński, Joanna Chorbińska, Łukasz Nowak, Jan Łaszkiewicz, Adam Gurwin, Magdalena Krajewska, Bartosz Małkiewicz, Tomasz Szydełko
{"title":"A cross-language analysis of urolithiasis patient online materials: Assessment across 24 European languages.","authors":"Wojciech Tomczak, Wojciech Krajewski, Katarzyna Grunwald, Adam Chełmoński, Joanna Chorbińska, Łukasz Nowak, Jan Łaszkiewicz, Adam Gurwin, Magdalena Krajewska, Bartosz Małkiewicz, Tomasz Szydełko","doi":"10.5173/ceju.2025.0045","DOIUrl":"10.5173/ceju.2025.0045","url":null,"abstract":"<p><strong>Introduction: </strong>Urolithiasis is a prevalent condition with several etiological factors, affecting up to 20% of the population and exhibiting high recurrence rates. Its strain on healthcare systems, exacerbated by high incidence and recurrence, often results in insufficient time for thorough diagnostics and counselling. Consequently, many patients seek easily accessible online sources of information. This study aimed to assess the readability and availability of online urolithiasis materials across 24 official European languages to compare readability across different source types.</p><p><strong>Material and methods: </strong>The phrase \"kidney stones\" was translated into all official European languages, and the first 50 search results for each language were retrieved. Non-functional websites, those requiring accounts or payments, and duplicates were excluded. Relevance was assessed using Google Translate to filter out results lacking medical information. Only patient-oriented materials were included for analysis. Obtained results were then classified by source category, and their readability was assessed using LIX formula.</p><p><strong>Results: </strong>A total of 723 articles were analysed. The English term yielded the highest number of results, followed by Spanish and Portuguese. Overall, the English articles performed best, being the only language with a mean LIX score below 40, which marks the threshold between \"somewhat hard\" and \"hard\" to read. Finnish, Lithuanian, and Hungarian materials had LIX scores significantly exceeding the threshold of 50, classifying them as \"very hard to read\" and among the most difficult to comprehend.A subgroup analysis revealed no statistically significant differences across the source classification.</p><p><strong>Conclusions: </strong>Online materials on kidney stones are generally too complex for patients, limiting their understanding and treatment adherence. Simplification of patient-oriented materials along with artificial intelligence utilisation could enhance comprehension. Improved awareness may promote adherence to preventive measures and help reduce the incidence and economic burden of urolithiasis.</p>","PeriodicalId":9744,"journal":{"name":"Central European Journal of Urology","volume":"78 2","pages":"221-227"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the performance of different formulae to assess eGFR in children after allogenic hematopoietic stem cell transplantation. 不同配方评估儿童同种异体造血干细胞移植后eGFR的性能比较。
IF 1.9
Central European Journal of Urology Pub Date : 2025-01-01 Epub Date: 2025-11-02 DOI: 10.5173/ceju.2025.0225
Katarzyna Gąsowska, Katarzyna Zachwieja, Jolanta Goździk, Dorota Drożdż
{"title":"Comparison of the performance of different formulae to assess eGFR in children after allogenic hematopoietic stem cell transplantation.","authors":"Katarzyna Gąsowska, Katarzyna Zachwieja, Jolanta Goździk, Dorota Drożdż","doi":"10.5173/ceju.2025.0225","DOIUrl":"https://doi.org/10.5173/ceju.2025.0225","url":null,"abstract":"<p><strong>Introduction: </strong>There is an ongoing debate concerning the right formula to estimate GFR in pediatric oncological patients or recipients of hematopoietic stem cell transplantation.</p><p><strong>Material and methods: </strong>We did a retrospective analysis of renal function data before and up-to 3 years post hematopoietic stem cell transplantation (HSCT). We checked the accuracy and bias of eGFR based on Revised <i>Bedside</i> Schwartz equation 2009 (Schwartz 2009), Flanders Metadata (FLANDERS), CKiD U25 Creatinine (U25CREA), and CKiD U25 Cystatin C (U25CYSC) against Creatinine-Cystatin C-Urea-based CKiD Equation (Schwartz Combined 2012) as the reference.</p><p><strong>Results: </strong>We included 179 patients (67.0% female, 20.7% chronic kidney disease) aged 8.5 (5.5) years. Overall eGFR based on the U25CYSC formula performed best (baseline and 3-year follow up percentage of values outside the confidence limits 3.9, and 3.3%, respectively). One year after HSCT the best performance was offered by Schwartz 2009 formula (2.8% of outliers). No other studied formula in the overall analysis had the percentage of outliers less than 5%. FLANDERS had lowest and U25CYSC highest mean error (0.21 vs -22.53 ml/min/1.73 m<sup>2</sup>, respectively). The root mean square error was lowest for FLANDERS (26.9) and highest for U25CYSC (32.36). Both 30% and 10% accuracy was highest for FLANDERS (91.06 and 42.46%, respectively), and lowest for U25CYSC (78.77 and 31.28%, respectively).</p><p><strong>Conclusions: </strong>There were small differences in accuracy between simpler eGFR formulae against the reference formula, however we observed differences in error. The U25CYSC offered best accuracy but largest error leading to underestimation of eGFR. Therefore, when applying given formula, one must be mindful of its potential limitations and potential inherent biases.</p>","PeriodicalId":9744,"journal":{"name":"Central European Journal of Urology","volume":"78 4","pages":"546-553"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12924077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147269821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is hospitalization still necessary? A systematic review of outpatient HoLEP over the last decade. 还需要住院治疗吗?近十年来门诊患者HoLEP的系统回顾。
IF 1.9
Central European Journal of Urology Pub Date : 2025-01-01 Epub Date: 2025-11-28 DOI: 10.5173/ceju.2025.0127
Gabi Shokaier, Anan Hussein, Tarek Taha
{"title":"Is hospitalization still necessary? A systematic review of outpatient HoLEP over the last decade.","authors":"Gabi Shokaier, Anan Hussein, Tarek Taha","doi":"10.5173/ceju.2025.0127","DOIUrl":"https://doi.org/10.5173/ceju.2025.0127","url":null,"abstract":"<p><strong>Introduction: </strong>Holmium laser enucleation of the prostate (HoLEP) is a well-established, size-independent surgical intervention for benign prostatic hyperplasia (BPH). Traditionally performed with overnight hospitalization, there is increasing interest in same-day discharge to reduce healthcare costs and improve patient satisfaction. This systematic review evaluates the feasibility, safety, efficacy, and cost-effectiveness of HoLEP as an outpatient procedure across all patient populations between 2015 and 2025.</p><p><strong>Material and methods: </strong>A systematic search of PubMed and Google Scholar was conducted in accordance with PRISMA guidelines, yielding 15 eligible studies including over 1,500 patients. Outcomes analyzed included same-day discharge rates, readmissions, complications, symptom improvement, and patient satisfaction. Subgroup analyses examined outcomes by age, comorbidities, prostate size, and anticoagulation status.</p><p><strong>Results: </strong>Same-day discharge (SDD) rates ranged from 60-90%, with contemporary studies achieving rates above 85% in unselected populations. Readmission rates were low (~2-5%), with no significant increase compared to inpatient care. Complication profiles were similar between outpatient and inpatient settings, with most being minor. Functional outcomes such as International Prostate Symptom Score and urinary flow rates showed marked improvement postoperatively, comparable to traditional HoLEP. Advanced laser technology, early surgery scheduling, and standardized post-anesthesia protocols were key facilitators. Cost analyses demonstrated per-case savings of $750-$840 with outpatient care. Older age and anticoagulation were not absolute contraindications for SDD when proper criteria were met.</p><p><strong>Conclusions: </strong>HoLEP can be safely and effectively performed as an outpatient procedure in most patients, offering comparable outcomes to inpatient care while reducing costs and enhancing patient satisfaction.</p>","PeriodicalId":9744,"journal":{"name":"Central European Journal of Urology","volume":"78 4","pages":"522-531"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12924062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147269836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the microbiome of bladder urine, upper urinary tract urine, and kidney stones in patients with urolithiasis. 尿石症患者膀胱尿、上尿路尿和肾结石微生物组的比较
IF 1.9
Central European Journal of Urology Pub Date : 2025-01-01 Epub Date: 2025-04-28 DOI: 10.5173/ceju.2025.0020
Joanna Chorbińska, Wojciech Krajewski, Paweł Karpiński, Łukasz Nowak, Wojciech Tomczak, Jan Łaszkiewicz, Katarzyna Pacyga-Prus, Sabina Górska, Bartosz Małkiewicz, Tomasz Szydełko
{"title":"Comparison of the microbiome of bladder urine, upper urinary tract urine, and kidney stones in patients with urolithiasis.","authors":"Joanna Chorbińska, Wojciech Krajewski, Paweł Karpiński, Łukasz Nowak, Wojciech Tomczak, Jan Łaszkiewicz, Katarzyna Pacyga-Prus, Sabina Górska, Bartosz Małkiewicz, Tomasz Szydełko","doi":"10.5173/ceju.2025.0020","DOIUrl":"10.5173/ceju.2025.0020","url":null,"abstract":"<p><strong>Introduction: </strong>It is believed that bacteria can be involved in the formation of all types of stones. The aim of study was to assess the urinary microbiome in patients with urolithiasis.</p><p><strong>Material and methods: </strong>The study group included 50 patients qualified for endoscopic treatment of urinary tract stones using: ureteroscopic lithotripsy (URSL), retrograde intrarenal surgery (RIRS), percutaneous nephrolithotripsy (PCNL), endoscopic combined intrarenal surgery (ECIRS). Before the procedure, patients were asked to collect urine and stool for analysis. Urine from the upper urinary tract and stone fragments were collected intraoperatively. The research material was subjected to 16S rRNA sequencing. The chemical composition of stones was assessed using Raman spectroscopy.</p><p><strong>Results: </strong>In the urinary bladder, upper urinary tract, and kidney stone microbiomes of patients with urolithiasis the predominant bacteria identified were: <i>Acinetobacter, Bifidobacterium, Corynebacterium, Cutibacterium, Paracoccus, Pseudomonas, Staphylococcus</i> and <i>Streptococcus</i>. Further analysis showed the relative similarity of the urinary bladder and upper urinary tract microbiomes and the dissimilarity of the kidney stone microbiome. A comparison of the upper urinary tract microbiome based on the method of urine collection and a comparison of urinary bladder and upper urinary tract microbiomes based on the presence of a DJ stent prior to the procedure showed no statistically significant differences.</p><p><strong>Conclusions: </strong>The microbiome of stones differs from the microbiome of urine, which may play a role in the pathogenesis of urolithiasis. Bladder urine and upper urinary tract urine microbiomes do not differ. Therefore, bladder urine can replace upper urinary tract urine in microbiome studies.</p>","PeriodicalId":9744,"journal":{"name":"Central European Journal of Urology","volume":"78 2","pages":"206-220"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379818/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of suction in revolutionising endourology: Is it the final frontier - an overview from EAU Endourology. 吸痰的作用在革命性的腔内学:它是最后的前沿-从EAU腔内学概述。
IF 1.9
Central European Journal of Urology Pub Date : 2025-01-01 Epub Date: 2025-05-25 DOI: 10.5173/ceju.2025.0105
Bhaskar K Somani, Vineet Gauhar, Steffi Kar Kei Yuen, Niall Davis, Ewa Bres-Niewada
{"title":"Role of suction in revolutionising endourology: Is it the final frontier - an overview from EAU Endourology.","authors":"Bhaskar K Somani, Vineet Gauhar, Steffi Kar Kei Yuen, Niall Davis, Ewa Bres-Niewada","doi":"10.5173/ceju.2025.0105","DOIUrl":"10.5173/ceju.2025.0105","url":null,"abstract":"","PeriodicalId":9744,"journal":{"name":"Central European Journal of Urology","volume":"78 2","pages":"181-183"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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