Cerebral cortex最新文献_第3页

Using parity cross-format adaptation to probe abstract number representation in the human brain. 利用奇偶跨格式自适应研究人脑抽象数表征。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-08-01 DOI: 10.1093/cercor/bhaf225

Talia L Retter, Henning Lütje, Christine Schiltz

{"title":"Using parity cross-format adaptation to probe abstract number representation in the human brain.","authors":"Talia L Retter, Henning Lütje, Christine Schiltz","doi":"10.1093/cercor/bhaf225","DOIUrl":"10.1093/cercor/bhaf225","url":null,"abstract":"It is debated whether there is an abstract, format-independent representation of number in the human brain, eg whether \"four\" shares a neural representation with \"4.\" Most previous studies have used magnitude to investigate this question, despite potential confounds with relative quantity processing. This study used the numerical property of parity. Electroencephalogram recordings were collected from participants performing a fixation-cross task, while viewing 20-s sequences of alternating even and odd Arabic numerals presented at 7.5 Hz: responses to parity were selectively tagged at the asymmetry frequency of 3.75 Hz. Parity asymmetry responses emerged significantly over the occipito-temporal (OT) cortex, and were larger than control asymmetry responses to isolated physical stimulus differences, replicating a previous study. Following 20-s adaptation to cross-font even numerals, larger parity responses were recorded over the right OT cortex, further supporting distinct representations of even/odd numbers; there was no corresponding control adaptation effect. Interestingly, adaptation to even canonical dot stimuli also produced significantly larger parity asymmetry responses; adaptation to even number words trended non-significantly. These results are in line with parity being processed automatically, even across formats. More generally, they suggest that parity is a useful means for probing abstract representation of number in the human brain.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 8","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144871678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Generalized learning induced by training and tDCS is predicted by prefrontal cortical morphology. 训练和tDCS诱导的泛化学习可通过前额皮质形态学进行预测。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-08-01 DOI: 10.1093/cercor/bhaf229

Shane E Ehrhardt, Yohan Wards, Thomas B Shaw, Kelly G Garner, Steffen Bollmann, Jason B Mattingley, Paul E Dux, Hannah L Filmer

{"title":"Generalized learning induced by training and tDCS is predicted by prefrontal cortical morphology.","authors":"Shane E Ehrhardt, Yohan Wards, Thomas B Shaw, Kelly G Garner, Steffen Bollmann, Jason B Mattingley, Paul E Dux, Hannah L Filmer","doi":"10.1093/cercor/bhaf229","DOIUrl":"https://doi.org/10.1093/cercor/bhaf229","url":null,"abstract":"Brain stimulation shows promise as an intervention to enhance executive function, particularly when paired with cognitive training. To optimize such approaches, we must understand the potential role of individual differences in intervention outcomes. We investigated the combined effects of multi-session multitasking training and prefrontal transcranial direct current stimulation (tDCS) on generalization of performance benefits, focusing on how cortical morphology predicts performance improvements. One hundred seventy-eight individuals underwent 7 Tesla MRI before completing multisession training with online stimulation. A cognitive task battery assessed improvements in trained and untrained tasks pre- and post-training. Stimulating the left or right prefrontal cortex at 1 mA during multitasking training enhanced transfer to a visual search task. Critically, cortical morphology predicted stimulation efficacy for inducing transfer. Cortical thickness in regions beneath the stimulating anode was related to reaction time changes in the most difficult visual search condition but only for the left and right 1 mA multitasking training groups. Performance was not related to cortical thickness for the groups receiving sham stimulation, 2 mA stimulation, or 1 mA stimulation with a control training task. These results highlight the importance of individual anatomical differences in modulating tDCS efficacy and identifying specific neuroanatomical features that predict generalized performance gains from combining tDCS with cognitive training.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 8","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12365975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cortico-hippocampal interactions underlie schema-supported memory encoding in older adults. 皮层-海马体相互作用是老年人图式支持记忆编码的基础。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-08-01 DOI: 10.1093/cercor/bhaf211

Shenyang Huang, Paul C Bogdan, Cortney M Howard, Kirsten Gillette, Lifu Deng, Erin Welch, Margaret L McAllister, Kelly S Giovanello, Simon W Davis, Roberto Cabeza

{"title":"Cortico-hippocampal interactions underlie schema-supported memory encoding in older adults.","authors":"Shenyang Huang, Paul C Bogdan, Cortney M Howard, Kirsten Gillette, Lifu Deng, Erin Welch, Margaret L McAllister, Kelly S Giovanello, Simon W Davis, Roberto Cabeza","doi":"10.1093/cercor/bhaf211","DOIUrl":"10.1093/cercor/bhaf211","url":null,"abstract":"Although episodic memory is typically impaired in older adults (OAs) compared to young adults (YAs), this deficit is attenuated when OAs can leverage their rich semantic knowledge, such as their knowledge of schemas. Memory is better for items consistent with pre-existing schemas and this effect is larger in OAs. Neuroimaging studies have associated schema use with the ventromedial prefrontal cortex (vmPFC), angular gyrus (AG), and hippocampus (HPC), but most of this research has been limited to YAs. This fMRI study investigated the neural mechanisms underlying how schemas boost episodic memory in OAs. Participants encoded scene-object pairs with varying congruency, and memory for the objects was tested the following day. Congruency with schemas enhanced object memory for YAs and, more substantially, for OAs. fMRI analyses examined cortico-hippocampal interactions at encoding. We found that a vmPFC-HPC interaction was related to enhanced subsequent memory for congruent objects in both age groups, whereas an AG-HPC interaction contributed to subsequent memory for congruent objects only in OAs. Individual difference analyses of the AG-HPC interaction suggested that OAs made use of semantic knowledge to facilitate encoding. Collectively, our findings illustrate age-related differences in how schemas influence episodic memory encoding via distinct cortico-hippocampal interactions.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 8","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing the neural bases of self- and social-reappraisal. 自我与社会重评的神经基础比较。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-08-01 DOI: 10.1093/cercor/bhaf189

Zhouzhou He, Noga Cohen, Jocelyn Shu, Ke Bo, Tor D Wager, Kevin N Ochsner

{"title":"Comparing the neural bases of self- and social-reappraisal.","authors":"Zhouzhou He, Noga Cohen, Jocelyn Shu, Ke Bo, Tor D Wager, Kevin N Ochsner","doi":"10.1093/cercor/bhaf189","DOIUrl":"https://doi.org/10.1093/cercor/bhaf189","url":null,"abstract":"To manage life's stressors, we can self-regulate our emotions or seek social regulatory support. One such strategy is reappraisal, where individuals reframe their own negative emotions (ie self-reappraisal) or help others reframe their negative emotions (ie social-reappraisal). Here, we compared the neural mechanisms underlying self- and social-reappraisal of negative autobiographical memories using standard univariate contrasts, Bayes factor, and multivariate classifier approaches. Both self- and social-reappraisal recruited regions associated with control and mentalizing, such as dorsolateral and ventrolateral prefrontal cortex and dorsomedial prefrontal cortex. However, social-reappraisal was qualitatively different from self-reappraisal in its recruitment of additional control and mentalizing regions, such as the right lateral prefrontal cortex, medial prefrontal cortex, and right temporal pole. Notably, multivariate patterns within regions associated with mentalizing-but not control-were distinguishable between self- and social-reappraisal, suggesting that different kinds of information are drawn upon when reappraising for self vs. others. Finally, both self- and social-reappraisal modulated activity in regions associated with affective responding and the perceptual representation of remembered scenes, including the mid-orbital frontal cortex, left insula, and posterior parahippocampal gyrus. Taken together, these data reveal the processes supporting self and social emotion regulation with implications for both basic and clinical research.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 8","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144774742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Compositionality in the semantic network: a model-driven representational similarity analysis. 语义网络中的组合性：模型驱动的表征相似性分析。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-08-01 DOI: 10.1093/cercor/bhaf246

Marco Ciapparelli, Marco Marelli, William Graves, Carlo Reverberi

{"title":"Compositionality in the semantic network: a model-driven representational similarity analysis.","authors":"Marco Ciapparelli, Marco Marelli, William Graves, Carlo Reverberi","doi":"10.1093/cercor/bhaf246","DOIUrl":"10.1093/cercor/bhaf246","url":null,"abstract":"Semantic composition allows us to construct complex meanings (e.g., \"dog house\", \"house dog\") from simpler constituents (\"dog\", \"house\"). Neuroimaging studies have often relied on high-level contrasts (e.g., meaningful > non-meaningful phrases) to identify brain regions sensitive to composition. However, such an approach is less apt at addressing how composition is carried out, namely what functions best characterize constituents integration. Here, we rely on simple computational models to explicitly characterize alternative compositional operations, and use representational similarity analysis to compare models to target regions of interest. We re-analyze fMRI data aggregated from four published studies (N = 85), all employing two-word combinations but differing in task requirements. Confirmatory and exploratory analyses reveal compositional representations in the left inferior frontal gyrus (BA45), even when the task did not require semantic access. These results suggest that BA45 represents combinatorial information automatically across task demands, and further characterize composition as the (symmetric) intersection of constituent features. Additionally, a cluster of compositional representations emerges in the left middle superior temporal sulcus, while semantic, but not compositional, representations are observed in the left angular gyrus. Overall, our work clarifies which brain regions represent semantic information compositionally across contexts and tasks, and qualifies which operations best describe composition.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 8","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The left pars triangularis lesions impair semantic interference resolution regardless of competitor modality. 无论竞争模式如何，左三角部损伤都会损害语义干扰分辨率。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-08-01 DOI: 10.1093/cercor/bhaf215

Andrey Zyryanov, Olga Buivolova, Olga Dragoy, Svetlana Malyutina

{"title":"The left pars triangularis lesions impair semantic interference resolution regardless of competitor modality.","authors":"Andrey Zyryanov, Olga Buivolova, Olga Dragoy, Svetlana Malyutina","doi":"10.1093/cercor/bhaf215","DOIUrl":"10.1093/cercor/bhaf215","url":null,"abstract":"When we speak, selecting the right word takes longer whenever its semantic associates become active simultaneously. Although such semantic interference (SI) activates the left inferior frontal gyrus (LIFG), its lesions do not systematically increase SI induced by written word distractors. Therefore, whether the LIFG plays a causal role in resolving SI remains an open question. We hypothesized that it does, but the influence of LIFG lesions on SI from a written distractor in a given trial is obscured by concurrent interference from participants' own spoken responses in preceding trials. To test this hypothesis, we disentangled SI from these two competitor modalities in 25 post-stroke individuals who performed a picture-word interference task. Supporting the hypothesis, larger lesions to the pars triangularis of the LIFG increased SI from participants' previous spoken responses whenever they were semantically related to the current response. With this effect accounted for, larger pars triangularis lesions also increased SI from semantically related written distractors. In contrast, lesions to all other examined neuroanatomical regions either decreased or did not influence SI. Thus, the left pars triangularis does play a causal role in resolving SI regardless of competitor modality.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 8","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eight-week high intensity jump training does not change neural correlates of executive functions and emotion regulation in young adults. 8周高强度跳跃训练对青少年执行功能和情绪调节的神经相关功能没有影响。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-08-01 DOI: 10.1093/cercor/bhaf228

Lara A Wallenwein, Stephanie N L Schmidt, Philipp Barzyk, Maik Bieleke, Julia Schüler, Markus Gruber, Daniela Mier

{"title":"Eight-week high intensity jump training does not change neural correlates of executive functions and emotion regulation in young adults.","authors":"Lara A Wallenwein, Stephanie N L Schmidt, Philipp Barzyk, Maik Bieleke, Julia Schüler, Markus Gruber, Daniela Mier","doi":"10.1093/cercor/bhaf228","DOIUrl":"10.1093/cercor/bhaf228","url":null,"abstract":"Exercise can positively impact cognitive abilities. However, studies assessing the impact of exercise on related constructs, such as emotion regulation, are missing. Further, little is known about the effects of exercise on cognition and accompanying changes in neural activation in healthy young adults. In this randomized controlled trial, we tested the effect of a chronic exercise intervention with an extensive set of tasks probing executive functioning and emotion regulation in fMRI. University students were either assigned to an 8-week high intensity low volume jump training intervention or to a control group. Physical fitness measurements and fMRI-scans during working memory, task switching, response inhibition, and cognitive reappraisal of 58 participants were analyzed. The training intervention resulted in an expected improvement in jump performance but not in aerobic capacity. Moreover, the training did not improve executive functioning or emotion regulation performance. While we found strong fronto-parietal brain activation over both timepoints, the training resulted only in insubstantial changes. Likewise, individual changes in aerobic capacity and jump performance were not related to improvements in cognitive performance or changes in brain activation. In conclusion, our study does not support positive effects of exercise interventions on executive functions or emotion regulation in healthy young adults.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 8","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neural alpha oscillations and auditory steady-state responses during adaptation to a cochlear implant. 人工耳蜗适应过程中的神经振荡和听觉稳态反应。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-08-01 DOI: 10.1093/cercor/bhaf244

Malte Wöstmann, Hannah Marie Meineke, Rainer Schönweiler, Daniela Hollfelder, Karl-Ludwig Bruchhage, Anke Leichtle, Jonas Obleser

{"title":"Neural alpha oscillations and auditory steady-state responses during adaptation to a cochlear implant.","authors":"Malte Wöstmann, Hannah Marie Meineke, Rainer Schönweiler, Daniela Hollfelder, Karl-Ludwig Bruchhage, Anke Leichtle, Jonas Obleser","doi":"10.1093/cercor/bhaf244","DOIUrl":"10.1093/cercor/bhaf244","url":null,"abstract":"The human auditory system must distinguish relevant sounds from noise. Severe hearing loss can be treated with cochlear implants (CIs), but how the brain adapts to electrical hearing remains unclear. This study examined adaptation to unilateral CI use in the first and seventh months after CI activation using speech comprehension measures and electroencephalography recordings, both during passive listening and an active spatial listening task. Neural phase-locking to amplitude-modulated sounds interacted with time, such that phase-locking longitudinally increased stronger for 40 Hz compared with 4 Hz. In the spatial listening task, the benefit of performing the task with the CI on vs. off was most pronounced when the CI ear was primarily exposed to target speech. Lateralized alpha oscillations (~10 Hz) reliably marked CI users' focus of spatial attention. Stronger alpha modulation in the hemisphere opposite to the nonimplanted ear indicates an attentional bias toward the acoustically hearing ear. Our findings suggest that adaptation to hearing with a CI is accomplished by dynamic changes in auditory phase locking and a bias in auditory spatial attention.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 8","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Activity of CaMKII-expressing neurons in medial prefrontal cortex of male and female Long-Evans rats is necessary for encoding odor information and novelty recognition in an odor-based incidental memory test. 在基于气味的附带记忆测试中，雄性和雌性Long-Evans大鼠内侧前额叶皮层表达camkii的神经元的活动是编码气味信息和新颖性识别所必需的。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-08-01 DOI: 10.1093/cercor/bhaf203

Ilne L Barnard, Dan L McElroy, Kaylen M Young, Dylan J Terstege, Aiden E Glass, Jonathan R Epp, Justin J Botterill, John G Howland

{"title":"Activity of CaMKII-expressing neurons in medial prefrontal cortex of male and female Long-Evans rats is necessary for encoding odor information and novelty recognition in an odor-based incidental memory test.","authors":"Ilne L Barnard, Dan L McElroy, Kaylen M Young, Dylan J Terstege, Aiden E Glass, Jonathan R Epp, Justin J Botterill, John G Howland","doi":"10.1093/cercor/bhaf203","DOIUrl":"10.1093/cercor/bhaf203","url":null,"abstract":"Incidental memories encoded through spontaneous interaction with stimuli in an environment contribute to higher cognitive functions. The spontaneous Identical (IST) and the Different Stimuli Tests (DST), with objects and odors, allow for incidental memory testing using variable memory loads in rats. Here, fiber photometry and chemogenetics were used to examine the necessity of CaMKII-expressing neurons in medial prefrontal cortex (mPFC) for novelty discrimination in the IST and DST with odors. Male and female Long Evans rats completed 6-odor IST and DST. No differences in total exploration times or stimuli visits were observed in either test or sex. During the sample phase of the DST, a heightened response and a sustained increase in mPFC neuronal activity occurred during the first stimulus interaction. A sustained increase in mPFC neuronal activity during interaction with the novel stimulus was also observed in the test phase of the DST, but not the IST. Activation of inhibitory DREADDs expressed in mPFC CaMKII-expressing neurons impaired novelty preference in the DST, but not IST, and significantly decreased c-Fos + cells in the mPFC. Taken together, we show increased activity in mPFC CaMKII-expressing neurons facilitates novelty recognition under higher memory loads in the DST.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 8","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12317376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144768449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Decoding semantic sound categories in early visual cortex. 早期视觉皮层语义声音类别的解码。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-08-01 DOI: 10.1093/cercor/bhaf208

Giusi Pollicina, Samuel A Müller, Polly Dalton, Petra Vetter

{"title":"Decoding semantic sound categories in early visual cortex.","authors":"Giusi Pollicina, Samuel A Müller, Polly Dalton, Petra Vetter","doi":"10.1093/cercor/bhaf208","DOIUrl":"10.1093/cercor/bhaf208","url":null,"abstract":"Early visual cortex, once thought to be exclusively used for visual processes, has been shown to represent auditory information in the absence of visual stimulation. However, the exact information content of these representations is still unclear, as is their degree of specificity. Here, we acquired functional magnetic resonance imaging (fMRI) data while blindfolded human participants listened to 36 natural sounds, hierarchically organized into semantic categories. Multivoxel pattern analysis revealed that animate and inanimate sounds, as well as human, animal, vehicle, and object sounds could be decoded from fMRI activity patterns in early visual regions V1, V2, and V3. Further, pairwise classification of the different sound categories demonstrated that sounds produced by humans were represented in early visual cortex more distinctively than other semantic categories. Whole-brain searchlight analysis showed that sounds could be decoded also in higher level visual and multisensory brain regions. Our findings extend our understanding of early visual cortex function beyond visual feature processing and show that semantic and categorical sound information is represented in early visual cortex, potentially used to predict visual input.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 8","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12317377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144768450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0