Cerebral cortex最新文献_第3页

Correction to: The microgravity environment affects sensorimotor adaptation and its neural correlates.

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-02-05 DOI: 10.1093/cercor/bhaf050

引用次数: 0

Functional gradient of the fusiform gyrus and its underlying molecular basis.

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-02-05 DOI: 10.1093/cercor/bhaf029

Jingyao Chen, Siyu Liu, Yuhao Shen, Huanhuan Cai, Wenming Zhao, Yongqiang Yu, Jiajia Zhu

{"title":"Functional gradient of the fusiform gyrus and its underlying molecular basis.","authors":"Jingyao Chen, Siyu Liu, Yuhao Shen, Huanhuan Cai, Wenming Zhao, Yongqiang Yu, Jiajia Zhu","doi":"10.1093/cercor/bhaf029","DOIUrl":"https://doi.org/10.1093/cercor/bhaf029","url":null,"abstract":"Evidence has evinced the functional complexity, anatomical heterogeneity, connectivity diversity, and clinical relevance of the fusiform gyrus. We aimed to investigate the hierarchical organization of the fusiform gyrus and its underlying molecular basis. Resting-state functional MRI data of 793 healthy subjects were collected from a discovery dataset and two independent cross-scanner, cross-race validation datasets. Functional gradients of the fusiform gyrus were calculated based on the voxel-wise fusiform gyrus-to-cerebrum functional connectivity to reflect its functional organization. Transcription-neuroimaging spatial correlation analysis was performed to determine genes with expression levels tracking the fusiform gyrus functional gradient. The dominant functional gradient that explained the greatest connectivity variance showed an anterior-posterior axis across the fusiform gyrus. More important, there was a strong association between the fusiform gyrus-dominant gradient and gene expression profiles, with two gene sets contributing significantly to this association yet differing in their specific expression and functional annotation. In addition, the fusiform gyrus-dominant gradient was linked closely to intrinsic geometry, slightly to cortical morphology, and gradually to behavioral domains from high-level cognitive processes to low-level sensory functions. Our findings add to the extant knowledge regarding the topographic organization of the fusiform gyrus by informing a novel conceptualization of how functional heterogeneity and multiplicity co-occur within the fusiform gyrus.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 2","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neural correlates of reciprocity bias: social debts modulate unfairness perception of violation during third-party observation. 互惠偏见的神经关联：社会债务对第三方观察中违规不公平感知的调节。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-02-05 DOI: 10.1093/cercor/bhae497

Yinling Zhang, Rongrong Chen, Siqi Liu, Peiqi Chen, Xiaoqin Mai

{"title":"Neural correlates of reciprocity bias: social debts modulate unfairness perception of violation during third-party observation.","authors":"Yinling Zhang, Rongrong Chen, Siqi Liu, Peiqi Chen, Xiaoqin Mai","doi":"10.1093/cercor/bhae497","DOIUrl":"10.1093/cercor/bhae497","url":null,"abstract":"The phenomenon of beneficiaries ignoring benefactors' violations, ranging from everyday favors to bribes, is widespread yet lacks targeted theoretical and empirical attention. We propose a conceptual framework that includes \"social debt\" and \"reciprocity bias,\" where \"social debt\" is defined as information about benefits bestowed by benefactors and \"reciprocity bias\" as the influence of social debt on beneficiaries' perceptions and decisions in situations involving the benefactor. To investigate this bias in moral perception and its cognitive-neural mechanisms, we manipulated three levels of social debt (none, less, more) by varying the amount of unasked benefits that benefactors bestowed upon participants. Participants then observed the distributor's fair or unfair allocation of resources to another person, while their electroencephalography (EEG) was recorded. Results indicate that more (vs. none/less) social debt reduces perceptions of unfairness toward benefactors' violations and enhances fairness perceptions of their norm adherence. This was, accompanied by the diminished fairness effect on fronto-centered P2 and a reversal fairness effect on the power of theta oscillations (4 to 7 Hz). These findings support a multilevel reciprocity bias in fairness perception, suggesting that strong social debt may heighten concern for benefactor's interests and increase the adaptive value of their violations at the cognitive-neural level.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Amygdala-centered fusional connections characterized nonmotor symptoms in Parkinson's disease. 以杏仁核为中心的融合连接是帕金森病非运动症状的特征。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-02-05 DOI: 10.1093/cercor/bhaf002

Yi Zhang, Sixiu Li, Jiali Yu, Rong Li, Wei Liao, Qin Chen, Haoyang Xing, Fengmei Lu, Xiaofei Hu, Huafu Chen, Qing Gao

{"title":"Amygdala-centered fusional connections characterized nonmotor symptoms in Parkinson's disease.","authors":"Yi Zhang, Sixiu Li, Jiali Yu, Rong Li, Wei Liao, Qin Chen, Haoyang Xing, Fengmei Lu, Xiaofei Hu, Huafu Chen, Qing Gao","doi":"10.1093/cercor/bhaf002","DOIUrl":"10.1093/cercor/bhaf002","url":null,"abstract":"The importance of nonmotor symptoms in understanding the pathogenesis of the heterogeneity of Parkinson's disease has been highlighted. However, the validation of specific brain network biomarkers in nonmotor symptom subtypes is currently lacking. By performing a new approach to compute functional connectivity with structural prior using magnetic resonance imaging, the present study computed both functional connectivity and fusional connectivity features in the nonmotor symptom subtypes of Parkinson's disease, one characterized by cognitive impairment with late onset and the other depression with early onset. The functional connectivity and fusional connectivity features centered at the left amygdala were both detected. The fusional features significantly enhanced the classification performance. The amygdala-postcentral and amygdala-orbital frontal features were critical for cognitive impairment with late onset detection, while the amygdala-temporooccipital features were crucial for depression with early onset detection. Additionally, the fusional connectivity features between the amygdala and the junction sulcus of parietooccipital and temporooccipital regions contributed significantly to differentiating cognitive impairment with late onset and depression with early onset. The within-subtype correlation analysis revealed that age at onset and cognitive scores were associated with features of amygdala-somatosensory/visual-motor processing areas in cognitive impairment with late onset, while related to features of amygdala-emotional processing areas in depression with early onset. Our findings highlighted distinct amygdala-centered fusional connectivity features related to diverse nonmotor symptoms in Parkinson's disease, offering new insights for pathogenesis-targeted treatments for specific Parkinson's disease subtypes.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143000942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifying causal neural oscillations underlying working memory. 识别工作记忆背后的因果神经振荡。

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-02-05 DOI: 10.1093/cercor/bhae492

Mina Mirjalili, Reza Zomorrodi, Zafiris J Daskalakis, Daniel M Blumberger, Sean L Hill, Tarek K Rajji

{"title":"Identifying causal neural oscillations underlying working memory.","authors":"Mina Mirjalili, Reza Zomorrodi, Zafiris J Daskalakis, Daniel M Blumberger, Sean L Hill, Tarek K Rajji","doi":"10.1093/cercor/bhae492","DOIUrl":"10.1093/cercor/bhae492","url":null,"abstract":"Electroencephalography is instrumental in understanding neurophysiological mechanisms underlying working memory. While numerous studies have associated electroencephalography features to working memory, understanding causal relationships leads to better characterization of the neurophysiological mechanisms that are directly linked to working memory. Personalized causal modeling is a tool to discover these direct links between brain features and working memory performance. Therefore, we applied this approach to electroencephalography data from 66 adult healthy participants collected while performing a 3-back working memory task. Using graphical causal modeling, we discovered causal neural oscillations of working memory performance and compared the causal features between two groups: high and low performers. Total number of causal features in high performers was higher than low performers. Among the causal features, right temporal gamma oscillation was ~5 times (z-score = 3.87, P = 0.0001) more frequently a causal feature among high performers than low performers. However, the power of causal temporal gamma oscillation was not different between the two groups. Our findings suggest that one potential approach to improve working memory performance is to induce more causal gamma oscillations. This can be achieved by generating more local gamma entrainment over the right temporal cortex, rather than simply increasing gamma power.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Welcome from the new Editor-in-Chief.

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-02-05 DOI: 10.1093/cercor/bhaf036

Marina A Pavlova

引用次数: 0

Electrophysiological activity underlying motor inhibition facilitated by touch.

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-02-05 DOI: 10.1093/cercor/bhaf009

Yuting Tang, Xiaotong Zhang, Houmin Wang, Yuxin Gao, Jianlin Ou, Zhuoming Chen, Jinyi Long

{"title":"Electrophysiological activity underlying motor inhibition facilitated by touch.","authors":"Yuting Tang, Xiaotong Zhang, Houmin Wang, Yuxin Gao, Jianlin Ou, Zhuoming Chen, Jinyi Long","doi":"10.1093/cercor/bhaf009","DOIUrl":"10.1093/cercor/bhaf009","url":null,"abstract":"Tactile sensory information obtained from oneself or others may provide a calming effect and has been shown to enhance participants' motor control. The extent to which these touch activities may support motor inhibition and the related electrophysiological mechanisms remain unknown. Here, we investigated these effects in twenty healthy volunteers via electroencephalography under 3 touching conditions (self-touch, other-touch, and no-touch) during a stop-signal task. We found that both the self-touch and other-touch conditions resulted in better stopping accuracy and lower stop-signal reaction times than the no-touch condition. Additionally, these 2 touch conditions elicited larger N2 and P3 responses during successful inhibition of planned finger movements. Time-varying network analysis based on electroencephalography was further used to explore the differences in brain networks during conflict monitoring substages under different touch conditions. A top-down projection from the frontal cortex (Fz) to the parietal and occipital cortices was observed along with increased functional connectivity efficiency under touch conditions. These results indicate that tactile information may enhance neural processing efficiency in the human brain by eliciting larger event-related potential components and promoting information processing in the brain network during conflict monitoring processes, thereby contributing to the reactive inhibitory component of motor inhibition.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Distinct insula subdivisions of resting-state functional connectivity in individuals with opioid and methamphetamine use disorders.

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-02-05 DOI: 10.1093/cercor/bhaf014

Wenhan Yang, Xinwen Wen, Zhe Du, Longtao Yang, Yanjing Chen, Jun Zhang, Kai Yuan, Jun Liu

{"title":"Distinct insula subdivisions of resting-state functional connectivity in individuals with opioid and methamphetamine use disorders.","authors":"Wenhan Yang, Xinwen Wen, Zhe Du, Longtao Yang, Yanjing Chen, Jun Zhang, Kai Yuan, Jun Liu","doi":"10.1093/cercor/bhaf014","DOIUrl":"https://doi.org/10.1093/cercor/bhaf014","url":null,"abstract":"Different addictive drugs can impact the function and morphology of the brain in diverse ways. The insula cortex, an important brain node involved in craving and reward neural circuits in individuals with substance use disorders (including damage to the insula cortex), has been reported to reduce addictive behaviors. However, less is known about whether there is a functional difference between individuals with opioid and methamphetamine use disorders, especially regarding the function of the insula cortex. Fifty-eight individuals with opioid use disorder and sixty individuals with methamphetamine use disorder underwent resting-state and 3D-T1-weighted magnetic resonance imaging and completed craving questionnaires. Differences in insula subdivision resting-state functional connectivity between the groups were assessed, and their correlations with craving were analyzed. Compared with the methamphetamine group, the opioid group demonstrated increased connectivity of the right dorsal anterior insula but decreased connectivity of the right posterior insula and the left dorsal anterior insula/posterior insula/ventral anterior insula. Additionally, a negative correlation between functional connectivity and craving was observed in individuals with opioid and methamphetamine use disorders. This study provides insights into the various brain function connection patterns that are associated with different types of drug use with respect to opioid and methamphetamine use disorders.Highlights: ","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 2","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Who is afraid of innate knowledge?

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-02-05 DOI: 10.1093/cercor/bhaf018

Iris Berent

引用次数: 0

EEG during dynamic facial emotion processing reveals neural activity patterns associated with autistic traits in children.

IF 2.9 2区医学

Cerebral cortex Pub Date : 2025-02-05 DOI: 10.1093/cercor/bhaf020

Aron T Hill, Talitha C Ford, Neil W Bailey, Jarrad A G Lum, Felicity J Bigelow, Lindsay M Oberman, Peter G Enticott

{"title":"EEG during dynamic facial emotion processing reveals neural activity patterns associated with autistic traits in children.","authors":"Aron T Hill, Talitha C Ford, Neil W Bailey, Jarrad A G Lum, Felicity J Bigelow, Lindsay M Oberman, Peter G Enticott","doi":"10.1093/cercor/bhaf020","DOIUrl":"10.1093/cercor/bhaf020","url":null,"abstract":"Altered brain connectivity and atypical neural oscillations have been observed in autism, yet their relationship with autistic traits in nonclinical populations remains underexplored. Here, we employ electroencephalography to examine functional connectivity, oscillatory power, and broadband aperiodic activity during a dynamic facial emotion processing task in 101 typically developing children aged 4 to 12 years. We investigate associations between these electrophysiological measures of brain dynamics and autistic traits as assessed by the Social Responsiveness Scale, 2nd Edition (SRS-2). Our results revealed that increased facial emotion processing-related connectivity across theta (4 to 7 Hz) and beta (13 to 30 Hz) frequencies correlated positively with higher SRS-2 scores, predominantly in right-lateralized (theta) and bilateral (beta) cortical networks. Additionally, a steeper 1/f-like aperiodic slope (spectral exponent) across fronto-central electrodes was associated with higher SRS-2 scores. Greater aperiodic-adjusted theta and alpha oscillatory power further correlated with both higher SRS-2 scores and steeper aperiodic slopes. These findings underscore important links between facial emotion processing-related brain dynamics and autistic traits in typically developing children. Future work could extend these findings to assess these electroencephalography-derived markers as potential mechanisms underlying behavioral difficulties in autism.","PeriodicalId":9715,"journal":{"name":"Cerebral cortex","volume":"35 2","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11808805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0