Caspian Journal of Internal Medicine最新文献

Gastrointestinal bleeding following traumatic brain injury: A clinical study on predisposing factors and outcomes. 脑外伤后消化道出血：关于诱发因素和结果的临床研究。

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Caspian Journal of Internal Medicine Pub Date : 2024-09-07 eCollection Date: 2024-01-01 DOI: 10.22088/cjim.15.4.673

Mehdi Mahmoodkhani, Arvin Naeimi, Amirhosein Zohrehvand, Masih Sabouri, Mohammad Heidari

{"title":"Gastrointestinal bleeding following traumatic brain injury: A clinical study on predisposing factors and outcomes.","authors":"Mehdi Mahmoodkhani, Arvin Naeimi, Amirhosein Zohrehvand, Masih Sabouri, Mohammad Heidari","doi":"10.22088/cjim.15.4.673","DOIUrl":"10.22088/cjim.15.4.673","url":null,"abstract":"Background: Traumatic brain injury (TBI) is one of the most common causes of death and disability worldwide. Stress ulcers are common in critically ill patients and can lead to life-threatening gastrointestinal bleeding (GIB). This study investigates the impact of predisposing factors on GIB and outcomes of TBI patients.Methods: This retrospective cohort study included TBI patients admitted between February 2019 and November 2021. Patients' demographic information and clinical characteristics were collected and divided into Post-TBI GIB and No-GIB groups. During clinical follow-up, the Glasgow Outcome Score (GOS) and mortality were assessed. The correlation between predisposing factors and GIB was investigated.Results: Out of 164 eligible patients, 66.5% were males, and the mean age was 31.38 ± 13.44 years. There was a higher rate of severe TBIs (p<0.001), intra-axial lesions (P=0.014), hypotension at admission (p<0.001), and concurrent coagulopathies (p<0.001) in the Post-TBI GIB group compared to the No-GIB group. In contrast, the Glasgow Coma Scale (GCS) level upon admission and discharge (p<0.001) and serum hemoglobin level at admission (p<0.001) were lower in the Post-TBI GIB group than in the other group. Moreover, primary GCS (P=0.017) and hypotension at admission (P=0.009), spinal injury (P=0.028), and intra-axial brain injury (P=0.018) were independently associated with GIB in TBI patients.Conclusion: Primary GCS and hypotension at admission, spinal injury, and intra-axial brain injury are independent predictors for GIB in TBI patients. The presence of GIB in TBI patients is associated with worse neurological outcomes as assessed by GOS at approximately 18 months.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiple sclerosis in a patient with Takayasu's Arteritis: A case report. 一名高安动脉炎患者的多发性硬化症：病例报告。

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Caspian Journal of Internal Medicine Pub Date : 2024-09-07 eCollection Date: 2024-01-01 DOI: 10.22088/cjim.15.4.729

Mohammad Mehdi Emam, Mahdiye Abiyarghamsari, Muhanna Kazempour, Maryam Haghighi-Morad, Farane Farsad

引用次数: 0

Transesophageal echocardiography probe intubation or extubation: which side is generating more aerosols associated with spreading COVID-19 contamination? 经食道超声心动图探头插管或拔管：哪一侧产生的气溶胶更多与 COVID-19 污染扩散有关？

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Caspian Journal of Internal Medicine Pub Date : 2024-09-07 eCollection Date: 2024-01-01 DOI: 10.22088/cjim.15.4.748

Mohaddeseh Behjati, Fatemeh Tohidi

引用次数: 0

Effect of Plantago major on cough severity in acute bronchitis: A double-blind randomized clinical trial. 大车前草对急性支气管炎咳嗽严重程度的影响：双盲随机临床试验

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Caspian Journal of Internal Medicine Pub Date : 2024-09-07 eCollection Date: 2024-01-01 DOI: 10.22088/cjim.15.4.651

Alireza Naderi, Seyyed Ali Mozaffarpur, Hoda Shirafkan, Masomeh Bayani, Zahra Memariani

{"title":"Effect of Plantago major on cough severity in acute bronchitis: A double-blind randomized clinical trial.","authors":"Alireza Naderi, Seyyed Ali Mozaffarpur, Hoda Shirafkan, Masomeh Bayani, Zahra Memariani","doi":"10.22088/cjim.15.4.651","DOIUrl":"10.22088/cjim.15.4.651","url":null,"abstract":"Background: Treatments for acute bronchitis is usually a supportive care to relieve upper respiratory symptoms. This study aimed to evaluate the effect of Plantago major syrup (PMS) on cough severity in acute bronchitis.Methods: Patients (20-75 years-old) referred to the clinic of infectious diseases in Ayatollah Rouhani Hospital, Babol, Iran with a complaint of cough and the Bronchitis Severity Scale (BSS) ≥5 entered the study. The patients randomly received PMS or placebo 30 ml/day for 10 days. Patients were visited before treatment and on days 5 and 10 after treatment. The primary outcome was BSS score and secondary outcome was the life quality that was measured by means of the Persian version of the Leicester Cough Questionnaire (LCQ) at the first visit and on the 10th day.Results: Of the 121 patients diagnosed with acute bronchitis, 80 eligible patients (42.87±11.75 years-old) were randomly divided into PMS and placebo groups. The BSS score in the PMS group after 10 days was significantly lower than that of the placebo group (P=0.001). Frequency of cough (P=0.001), sputum production (P=0.005), and chest wall pain (P=0.008) were significantly lower in the PMS group than in the placebo group. In terms of quality of life, all items, including psychological, physical, and social domains, as well as total scores, were altered significantly in the PMS group compared to placebo. During monitoring of side effects, no significant adverse effects were stated in either group.Conclusion: The study indicates the palliative effects of PMS in relieving the symptoms of acute bronchitis and improving quality of life.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Residual kidney function and sleep quality in hemodialysis patients. 血液透析患者的剩余肾功能和睡眠质量。

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Caspian Journal of Internal Medicine Pub Date : 2024-09-07 eCollection Date: 2024-01-01 DOI: 10.22088/cjim.15.4.682

Elham Ramezanzade, Masoud Khosravi, Alireza Jafarinezhad, Sepideh Sadeghi Dehbane, Mirsaeed Attarchi

{"title":"Residual kidney function and sleep quality in hemodialysis patients.","authors":"Elham Ramezanzade, Masoud Khosravi, Alireza Jafarinezhad, Sepideh Sadeghi Dehbane, Mirsaeed Attarchi","doi":"10.22088/cjim.15.4.682","DOIUrl":"10.22088/cjim.15.4.682","url":null,"abstract":"Background: Sleep disorders frequently affect end-stage renal disease patients on dialysis. However, the relationship between sleep quality and residual kidney function is still unclear. Therefore, this study aimed to investigate this relationship.Methods: In this analytical cross-sectional study, 225 patients who were referred to dialysis centers were studied, and based on renal function, they were classified into two groups with and without residual kidney function. The study employed the Pittsburgh Sleep Quality Index questionnaire to evaluate sleep quality. Multiple linear regression was utilized to determine the factors affecting sleep quality with a significance level consideration at p<0.05.Results: The mean age of patients was 58.23 ± 13.50 years. 58.7% of patients were males. The problem of serious and very serious sleep in the Sleep latency and sleep duration has been more than other components. 72% of hemodialysis patients had poor sleep quality. In the multiple linear regression model, age (β = 0.442, 95% CI: 0.096, 0.788), sex (β = -0.847, 95% CI: -1.641, -0.054), Body mass index (β = 0.153, 95% CI: 0.058, 0.249) and dialysis duration (β = 0.097, 95% CI: 0.002, 0.192) were independently and significantly associated with sleep quality score. However, there was no statistically significant relationship between sleep quality and residual kidney function.Conclusion: In conclusion, poor sleep quality is very common in patients undergoing hemodialysis. Therefore, sleep disorders in hemodialysis patients should be considered as one of the most challenging problems by healthcare providers, and early diagnosis and intervention are essential to improve sleep quality.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concurrent peritoneal and pleural tuberculosis in an adult: A case report and literature review. 一名成人并发腹膜和胸膜结核：病例报告和文献综述。

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Caspian Journal of Internal Medicine Pub Date : 2024-09-07 eCollection Date: 2024-01-01 DOI: 10.22088/cjim.15.4.735

Elham Barahimi, Zahra Ghaeini Hesarooeyeh, Ayoub Basham, Mohadeseh Karimi, Behnoush Heidari

{"title":"Concurrent peritoneal and pleural tuberculosis in an adult: A case report and literature review.","authors":"Elham Barahimi, Zahra Ghaeini Hesarooeyeh, Ayoub Basham, Mohadeseh Karimi, Behnoush Heidari","doi":"10.22088/cjim.15.4.735","DOIUrl":"10.22088/cjim.15.4.735","url":null,"abstract":"Background: The simultaneous involvement of the pleura and peritoneum with tuberculosis in the absence of pulmonary foci is an uncommon condition that may lead physicians to misdiagnose.Case presentation: Herein, we present a Persian male adult who manifested with epigastric pain, weakness, and a history of pleuritic chest pain two months prior to admission. The findings of the physical examination included vital signs within the normal range, unilateral fine crackle in the lung, abdominal distension with positive shifting dullness, and fluid wave test. Analysis of the ascitic fluid revealed a Serum-ascites albumin gradient (SAAG) of less than 1.1g/dl, indicating a non-portal condition. The results of the acid-fast bacilli (AFB) staining as well as the TB polymerase chain reaction (PCR) test were negative. However, the adenosine deaminase (ADA) level was 44 IU/L. A chest CT scan revealed mediastinal lymph node enlargement and pleural thickening with loculated pleural effusion. Three acid-fast bacilli smear of morning sputum were sent, and all three were negative. An abdominopelvic CT scan showed multiple periaortic and mesenteric lymph nodes of varying sizes with mesenteric haziness and accumulation of effusion in the peritoneal cavity. Eventually, peritoneal biopsy, the gold standard, was performed, which revealed multiple granulomatous lesions and areas of caseous necrosis surrounded by Langerhans giant cells and epithelioid cells.Conclusion: It is worth noting that in cases of ascites and pleural thickening, especially in patients with poor socioeconomic status, simultaneous pleural and peritoneal TB should be considered, especially in third-world countries.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insulin-like growth factor (IGF) levels in pre-treatment plasma identifying breast cancer: A case control study. 乳腺癌治疗前血浆中的胰岛素样生长因子（IGF）水平：病例对照研究。

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Caspian Journal of Internal Medicine Pub Date : 2024-09-07 eCollection Date: 2024-01-01 DOI: 10.22088/cjim.15.4.706

Sarvin Alizadeh Sadighi, Nematollah Rostami, Maryam Tohidi, Mahbobeh Mashayekhi

{"title":"Insulin-like growth factor (IGF) levels in pre-treatment plasma identifying breast cancer: A case control study.","authors":"Sarvin Alizadeh Sadighi, Nematollah Rostami, Maryam Tohidi, Mahbobeh Mashayekhi","doi":"10.22088/cjim.15.4.706","DOIUrl":"10.22088/cjim.15.4.706","url":null,"abstract":"Background: Diabetes (primarily type 2) is linked to a higher risk of breast cancer. Insulin-like growth factor (IGF) is one of the most important factors that affects mitosis and thus inhibits apoptosis. The purpose of this study was to compare the pre-treatment insulin-like growth factor (IGF) levels in breast cancer against normal population.Methods: In this case-control study, 60 patients with breast cancer and 60 healthy controls were enrolled in 2017 and 2018 at Tehran's Shahid-Modarres Hospital. In this study, the blood sugar of the patients was examined before entering the study, and the age of the patients was also within the age limit of 18 to 70 years. They were studied to determine the relationship between insulin-like growth factor (ELISA method) and breast cancer.Results: Both groups have similar IGF-1 levels (Ctrl and Case) (P= 0.188). But, IGF-2 levels were significantly higher in breast cancer patients (373.4 vs. 317.3 ng/ml), (P=0.0001).Conclusion: According to our study, IGF-2 may serve as a prognostic biomarker and potential therapeutic target for breast cancer. However, further investigation is needed to validate this claim.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum lipid profile in adolescents and adults with acne vulgaris receiving isotretinoin. 接受异维A酸治疗的青少年和成人寻常型痤疮患者的血脂状况。

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Caspian Journal of Internal Medicine Pub Date : 2024-09-07 eCollection Date: 2024-01-01 DOI: 10.22088/cjim.15.4.659

Kaveh Gharaei Nejad, Abbas Darjani, Narges Alizadeh, Seyede Tahoura Hakemzadeh, Afagh Hassanzadeh Rad, Ehsan Kazemnejad-Leili, Reyhaneh Ghadarjani, Hojat Eftekhari, Rana Rafiei, Setila Dalili

{"title":"Serum lipid profile in adolescents and adults with acne vulgaris receiving isotretinoin.","authors":"Kaveh Gharaei Nejad, Abbas Darjani, Narges Alizadeh, Seyede Tahoura Hakemzadeh, Afagh Hassanzadeh Rad, Ehsan Kazemnejad-Leili, Reyhaneh Ghadarjani, Hojat Eftekhari, Rana Rafiei, Setila Dalili","doi":"10.22088/cjim.15.4.659","DOIUrl":"10.22088/cjim.15.4.659","url":null,"abstract":"Background: Acne vulgaris is a chronic, inflammatory disease and one of the most common skin diseases. Isotretinoin is the best treatment for severe nodulocystic acne compared to other systemic medicine. Although serum lipids elevation is one of the side effects of this medicine; recent studies have shown controversial results. This study aimed to assess the serum lipid profile in adolescents and adults with acne vulgaris receiving isotretinoin.Methods: This is a cross-sectional study on 65 adolescents and adults older than 16 years old (55 females and 10 males) with moderate to severe degrees of acne vulgaris under a fixed low dose of 20 mg/day Isotretinoin treatment for 120 days. We analyzed the data using the SPSS software Version 16 using paired sample t-test, Wilcoxon, and ANCOVA test.Results: In this study, 65 records of patients with a mean age of 22.21±6.25 years were assessed. There was a significant elevation in Cholesterol and LDL levels, but in HDL and triglyceride levels no significant change occurred. A significant change in cholesterol levels was noticed in the adolescent age group, the female sex, and the normal weight group. Triglyceride had a significant change in the female sex and normal weight group and HDL significantly increased in male patients.Conclusion: Although a low dose of isotretinoin can be used with minimal concern for changes in lipid profile in acne vulgaris patients, in the long-term follow-up and treatment, it seems that we have to administer it cautiously.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comparative study of the local effect of tranexamic acid and phenylephrine on the amount of bleeding in rhinoplasty: A randomized clinical trial. 氨甲环酸和苯肾上腺素对鼻整形术出血量的局部影响比较研究：随机临床试验。

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Caspian Journal of Internal Medicine Pub Date : 2024-09-07 eCollection Date: 2024-01-01 DOI: 10.22088/cjim.154.690

Hooshang Akbari, Ebrahim Nasiri Formi, Abbas Alipour, Hamed Delam, Esmaeil Kavi, Negar Shahkarami

{"title":"A comparative study of the local effect of tranexamic acid and phenylephrine on the amount of bleeding in rhinoplasty: A randomized clinical trial.","authors":"Hooshang Akbari, Ebrahim Nasiri Formi, Abbas Alipour, Hamed Delam, Esmaeil Kavi, Negar Shahkarami","doi":"10.22088/cjim.154.690","DOIUrl":"10.22088/cjim.154.690","url":null,"abstract":"Background: Bleeding during nose surgery is very important, because it can cause a problem in the surgeon's field of view and lead to an increase in the probability of surgical complications. The aim of this study was to compare the local effects of tranexamic acid and phenylephrine on bleeding in rhinoplasty.Methods: The present study is a double-blind clinical trial in which 98 patients who were candidates for rhinoplasty Shiraz were randomly divided into 49 groups of phenylephrine and tranexamic acid. In the first group, 1 cc of phenylephrine and in the second group, 1 cc of tranexamic acid was used locally and then the variables in the two groups were compared. The current study was approved by the Iranian Clinical Trial Registration Center with code IRCT20201205049602N1.Results: The average blood pressure and heart rate in the phenylephrine group first increased and then decreased, but in the tranexamic acid group decreased from the beginning to 30 minutes. Based on the results of the test, there was a difference between the two groups in terms of the amount of bleeding, and a statistically significant relationship was observed. The average bleeding volume was lower in the phenylephrine group (p<0.0001).Conclusion: Results of this study showed that the amount of bleeding in the phenylephrine group was lower than that of tranexamic acid. It is recommended to use phenylephrine in rhinoplasty surgery to reduce bleeding and improve the surgeon's vision.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 associated lung cavitary lesions: A case series. 与 COVID-19 相关的肺空洞性病变：病例系列

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Caspian Journal of Internal Medicine Pub Date : 2024-09-07 eCollection Date: 2024-01-01 DOI: 10.22088/cjim.15.4.713

Rama Bozorgmehr, Farzad Esmaili Tarki, Esmat Yazdi, Shahrzad Shahrokhi Nejad

{"title":"COVID-19 associated lung cavitary lesions: A case series.","authors":"Rama Bozorgmehr, Farzad Esmaili Tarki, Esmat Yazdi, Shahrzad Shahrokhi Nejad","doi":"10.22088/cjim.15.4.713","DOIUrl":"10.22088/cjim.15.4.713","url":null,"abstract":"Background: Our study discusses the probable etiologies and characteristics of pulmonary cavities in post-COVID-19 patients. A pulmonary cavity is a late complication of the disease, yet it has led to multiple referrals to our tertiary hospital in Tehran, Iran.Methods: We conducted a retrospective case-series study on 20 patients who were admitted to our center between April 2020 and September 2021. They were all diagnosed with COVID-19 and concomitantly developed pulmonary cavities. We assessed their electronic medical records in 2021 and compared their characteristics with other studies based on the available literature.Result: Of the 20 patients with cavities, 12 (60%) had been diagnosed with prior COVID-19, and 9 (45%) had type 2 diabetes mellitus. 9 patients (45%) had bacterial superinfections while 4 (44%) had fungal infections. All patients received corticosteroids, but only 4 (20%) were additionally administered Tocilizumab.Conclusion: COVID-19 patients can develop pulmonary cavities during recovery; however, this infrequent radiologic finding depends on specific risk factors.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0