Caspian Journal of Internal Medicine最新文献_第10页

Pathological characteristics predicting sentinel lymph node metastasis in early breast cancer patients. 预测早期乳腺癌患者前哨淋巴结转移的病理特征

IF 0.8

Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.3.472

Mohammad Esmaeil Akbari, Atieh Akbari, Saba Ebrahimian

{"title":"Pathological characteristics predicting sentinel lymph node metastasis in early breast cancer patients.","authors":"Mohammad Esmaeil Akbari, Atieh Akbari, Saba Ebrahimian","doi":"10.22088/cjim.15.3.472","DOIUrl":"10.22088/cjim.15.3.472","url":null,"abstract":"Background: In this study, we aimed to identify the predicting pathological factors affecting sentinel lymph node biopsy (SLNB) in patients with clinically node-negative breast cancer.Methods: Our single institution retrospective study was conducted at the Cancer Research Center of Shahid Beheshti University of Medical Sciences from 2018 to 2021. Data were imported into and analyzed using SPSS Version 28 for Windows (IBM Corp., Armonk, NY, USA).Results: Of the 76 patients who underwent SLNB, 43 (56.6%) had negative SLNB and 33 (43.4%) had positive SLNB which led to axillary lymph node dissection (ALND). The relationship between hormone receptor status (ER/PR/Her2), pathology type (IDC, ILC, DCIS, LCIS), tumor size, and Ki67 expression was assessed. According to the results, axillary lymph node involvement can be predicted based on the scores and results of the three variables: IDC tumor type, lympho vascular invasion (LVI), and Ki67 expression. The positive relationship between IDC tumor type and LVI with SLNB indicates that with positive IDC tumor type and LVI, there is a higher probability of positive axillary lymph nodes (3.88 times higher probability for IDC tumor type and 6.75 times higher probability for the LVI factor). However, when the Ki67 expression is lower, the probability of positive axillary lymph nodes is higher (3.58 times higher probability).Conclusion: IDC tumor type, LVI, and lower Ki67 expression are independent predictive factors of positive SLNB.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 3","pages":"472-477"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11246680/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141619431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of cognitive impairment (CI) in patients with multiple sclerosis (MS): A systematic review and meta-analysis. 多发性硬化症（MS）患者认知障碍（CI）的患病率：系统回顾和荟萃分析。

IF 0.8

Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.3.392

Mozhde Askari, Omid Mirmosayyeb, Fatemeh Fattahi, Hamed Ghoshouni, Elham Moases Ghaffary, Vahid Shaygannejad, Mahsa Ghajarzadeh

{"title":"Prevalence of cognitive impairment (CI) in patients with multiple sclerosis (MS): A systematic review and meta-analysis.","authors":"Mozhde Askari, Omid Mirmosayyeb, Fatemeh Fattahi, Hamed Ghoshouni, Elham Moases Ghaffary, Vahid Shaygannejad, Mahsa Ghajarzadeh","doi":"10.22088/cjim.15.3.392","DOIUrl":"10.22088/cjim.15.3.392","url":null,"abstract":"Background: One of the complications of multiple sclerosis (MS) is cognitive impairment (CI). The prevalence of CI is reported variously in previous studies. The goal of this systematic review and meta-analysis to estimate pooled prevalence of CI in patients with MS and also the prevalence of CI based on the type of applied test.Methods: Two independent researchers systematically searched PubMed, Scopus, EMBASE, Web of Science, and google scholar as well as gray literature (conference abstracts, references of the references) which were published before up January 2022.Results: We found 4089 articles by literature search, after deleting duplicates 3174 remained. Ninety articles remained for meta-analysis. The pooled prevalence of CI using all types of tests was 41% (95% CI: 38-44%) (I2=91.7%, p<0.001). The pooled prevalence of CI using BRB test was 39% (95%CI: 36-42%) (I2=89%, p<0.001). The pooled prevalence of CI using BICAMS was 44% (95%CI: 37-51%, I2=95.4%, p<0.001). The pooled prevalence of CI using MACFIMS was 44% (95% CI: 36-53%) (I2=89.3%, p<0.001).Conclusions: The pooled prevalence of cognitive impairment in patients with MS is estimated as 41%, so CI it should be considered by clinicians.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 3","pages":"392-413"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11246688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141619432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous Salmonella septic arthritis and naïve tricuspid valve endocarditis: A case report. 沙门氏菌脓毒性关节炎和三尖瓣心内膜炎同时存在：病例报告。

IF 0.8

Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.3.542

Mahnaz Arian, Farideh Najm Sarvari, Moein Mohebbi, Marzieh Kazerani

{"title":"Simultaneous Salmonella septic arthritis and naïve tricuspid valve endocarditis: A case report.","authors":"Mahnaz Arian, Farideh Najm Sarvari, Moein Mohebbi, Marzieh Kazerani","doi":"10.22088/cjim.15.3.542","DOIUrl":"10.22088/cjim.15.3.542","url":null,"abstract":"Background: Salmonella osteoarticular involvement is a rare complication, occurring in about 2% of the cases. Septic arthritis is exceedingly rare, involving only 0.2 % of all salmonellosis patients. Endocarditis is another complication that occurs in less than 0.8 % of cases. These complications are more likely to happen among immunocompromised patients.Case presentation: We report a previously healthy 25-year-old man who presented with left limb pain. He had been treated for brucellosis ten days earlier by his primary care physician. Arthrocentesis and subsequent hip-joint biopsy confirmed septic arthritis due to Salmonella. However, he was unresponsive to the treatment. We found no underlying immunosuppression. A trans-esophageal echo was performed due to the continued fever and positive blood cultures. It revealed Salmonella endocarditis of the naïve tricuspid valve. He was treated via arthrotomy and antimicrobials for four weeks. Follow-up after 20 months showed no underlying immunosuppression.Conclusion: This case highlights that in patients with positive Salmonella blood cultures and a focus of infection compatible with Salmonellosis but unresponsive to treatment, searching for other foci of infection is necessary. Furthermore, physicians in endemic areas of brucellosis should consider other differential diagnoses in patients with fever and limping because any delay in diagnosing Salmonella septic arthritis can destroy the joint space with lifelong discomfort.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 3","pages":"542-545"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11246686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141619437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The nosocomial infection survey among patients suffering from the Coronavirus disease-2019 hospitalized in Ayatollah Rouhani Hospital, Babol. 在巴博勒阿亚图拉-鲁哈尼医院住院的冠状病毒病-2019 患者中进行的院内感染调查。

IF 0.8

Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.3.509

Masomeh Bayani, Samaneh Rouhi, Rouzbeh Mohammadi Abandansari, Farzane Jafarian, Zahra Ahmadnia, Hossein Ghorbani, Alireza Firouzjahi, Mohammad Ranaee, Somayeh Ahmadi Goorji

{"title":"The nosocomial infection survey among patients suffering from the Coronavirus disease-2019 hospitalized in Ayatollah Rouhani Hospital, Babol.","authors":"Masomeh Bayani, Samaneh Rouhi, Rouzbeh Mohammadi Abandansari, Farzane Jafarian, Zahra Ahmadnia, Hossein Ghorbani, Alireza Firouzjahi, Mohammad Ranaee, Somayeh Ahmadi Goorji","doi":"10.22088/cjim.15.3.509","DOIUrl":"10.22088/cjim.15.3.509","url":null,"abstract":"Background: Having a weakened immune system can make patients easily get nosocomial infection (NI) with multi-drug resistant (MDR) bacteria and put them in a dangerous situation. It causes long hospital stays, disability, economic burden, and even death. The present study aimed to determine the prevalence of NI in patients suffering from COVID-19.Methods: In this retrospective study, the information on 250 patients suffering from COVID-19 in the intensive care unit (ICU) (2020 to 2021) was considered. For statistical analysis, analysis of variance (ANOVA), paired samples t-test, and chi-square using SPSS-23 software were used (p<0.05).Results: Two hundred and fifty hospitalized (107 females and 143 males, mean ± standard deviation (SD) of age; 56.50 ± 17.20) patients were considered. The most (97.60%) medicine prescribed was remdesivir. Candida spp. (two females), Escherichia coli (two females), Acinetobacter spp. (one female), Citrobacter spp. (one female), Pseudomonas spp. (one male), Sphingomonas spp. (one male), Stenotrophomonas spp. (one male) and Enterobacter spp. (one male) were isolated from the patient's specimens. Four of seven bacterial isolates were positive for MDR. NI was diagnosed in six patients. There was no significant relationship between the age with the isolated microbes (P=0.154) and MDR (P=0.987) and also between gender with common microbes (P=0.576) and MDR (P=0.143).Conclusion: The coexistence of bacteria and NI was observed in patients. Remdesivir was prescribed for most patients. Most bacteria were resistant to antibiotics, especially, β-lactams.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 3","pages":"509-518"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11246687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141619439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between MUC1 rs4072037 polymorphism and Helicobacter pylori in patients with gastric cancer. 胃癌患者的 MUC1 rs4072037 多态性与幽门螺旋杆菌之间的关系

IF 1.4

Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.1.15

Ramin Shekarriz, Hadi Jabbari, Reza Alikhani, Reza Alizadeh-Navaei, Mohammad Bagher Hashemi-Soteh

{"title":"Association between MUC1 rs4072037 polymorphism and Helicobacter pylori in patients with gastric cancer.","authors":"Ramin Shekarriz, Hadi Jabbari, Reza Alikhani, Reza Alizadeh-Navaei, Mohammad Bagher Hashemi-Soteh","doi":"10.22088/cjim.15.1.15","DOIUrl":"10.22088/cjim.15.1.15","url":null,"abstract":"Background: The MUC1 gene encodes glycoproteins attached to cell membrane that play a protective role in gastric cancer and protect epithelial surfaces against external factors such as Helicobacter pylori. H. pylori infection can induce a cascade of innate and acquired immune responses in gastric mucosa. Relationship between rs4072037G>A polymorphism of MUC1 gene and increased susceptibility to H. pylori infection aimed to investigate in patients with gastric cancer in Mazandaran, northern Iran.Methods: A case-control study was conducted on 99 patients with gastric cancer (H. pylori positive and negative) and 98 controls (H. pylori positive and negative) without gastric cancer (confirmed by pathological biopsy samples obtained during endoscopy). H. pylori infection was diagnosed by histological examination using Giemsa staining. Genomic DNA extracted from peripheral blood was analyzed by PCR-RFLP technique.Results: Analysis of all genetic models showed no significant relationship between rs4072037G>A polymorphism and risk of gastric cancer (GC). The relationship between H. pylori infection and rs4072037G>A polymorphism showed an increased susceptibility to gastric cancer in both positive and negative H. pylori groups (including case and control groups). The genetic model of GA/GG and H. pylori- positive versus GA/GG and H. pylori-negative showed a significantly increased susceptibility to gastric cancer (OR=0.251, CI: 0.128-0.493, P=0.000).Conclusion: These findings indicate that rs4072037G>A polymorphism may interact with H. pylori infection to increase the risk of GC.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 1","pages":"132-140"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10921109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140093398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation between neurofilament, HMGB1, MMP9, ds DNA blood levels and cognitive impairment in patients with neuropsychiatric systemic lupus erythematosus. 神经精神系统性红斑狼疮患者血液中神经丝蛋白、HMGB1、MMP9、ds DNA 水平与认知障碍之间的相关性。

IF 1.4

Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.1.6

Arman Ahmadzade, Leila Simani, Mehrdad Roozbeh, Farane Farsad, Mehdi Sheibani, Omid Negaresh, Mohammad Mehdi Emam, Alireza Rajaei, Muhanna Kazempour, Mahtab Ramezani, Samad Nazarpoor

{"title":"Correlation between neurofilament, HMGB1, MMP9, ds DNA blood levels and cognitive impairment in patients with neuropsychiatric systemic lupus erythematosus.","authors":"Arman Ahmadzade, Leila Simani, Mehrdad Roozbeh, Farane Farsad, Mehdi Sheibani, Omid Negaresh, Mohammad Mehdi Emam, Alireza Rajaei, Muhanna Kazempour, Mahtab Ramezani, Samad Nazarpoor","doi":"10.22088/cjim.15.1.6","DOIUrl":"10.22088/cjim.15.1.6","url":null,"abstract":"Background: Diagnosis of neuropsychiatric systemic lupus erythematosus (NPSLE) is challenging due to nonspecific biomarkers. High serum levels of neurofilament protein light subunit (NFL), high mobility group box 1 (HMGB1), Matrix metalloproteinase-9 (MMP-9) and have been reported in several autoimmune diseases. The aim of this study was to examine whether their plasma levels could serve as a diagnostic or prognostic biomarker for NPSLE.Methods: There were 90 SLE patients enrolled in this cross-sectional study (87.8% women and 12.2% men with a mean age of 41.67±11.05 years). We assessed the mental status of patients, also we measured the Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) and Systemic Lupus International Collaborating Clinics/ACR (SLICC/ ACR) Damage Index or SDI scores. Serum levels of NFL, HMGB1, MMP9, and ds-DNA were investigated to find a role in the pathophysiology of NPSLE.Results: Among the 90 patients with SLE, 63 (70%) met the criteria of NPSLE syndrome. Our results have shown a notable difference concerning SEDIAC-2k score, SDI score, PANS, MoCA, and Beck anxiety depression, between the two groups (p < 0.05). Although serum level of all measured serum biomarkers (NFL, MMP-9, HMGB1, dsDNA) were higher in patients with NPSLE, the difference was not statistically significant. Interestingly, our results showed that the serum level of NFL was correlated with the serum level of HMGB-1 and MMP-9. (r: 0.411, P=0.003).Conclusion: Serum level of NFL, HMGB-1 and MMP-9 may be used to detect abnormal mental status in patients with SLE.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 1","pages":"58-65"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10921114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140093401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preventive behaviors of COVID-19 in the Iranian adult population during the pandemic: Integrated effect of the health belief model and the planned behavior intention using causal path analysis. 大流行期间伊朗成年人的 COVID-19 预防行为：利用因果路径分析法分析健康信念模式和计划行为意向的综合影响。

IF 1.4

Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.1.13

Erfaneh Hajian-Tilaki, Karimollah Hajian-Tilaki, Afsaneh Bakhtiari

{"title":"Preventive behaviors of COVID-19 in the Iranian adult population during the pandemic: Integrated effect of the health belief model and the planned behavior intention using causal path analysis.","authors":"Erfaneh Hajian-Tilaki, Karimollah Hajian-Tilaki, Afsaneh Bakhtiari","doi":"10.22088/cjim.15.1.13","DOIUrl":"10.22088/cjim.15.1.13","url":null,"abstract":"Background: This study aimed to investigate the integration of the health belief model (HBM) and the theory of intention to plan preventive behavior for COVID-19 during the pandemic.Methods: In a cross-sectional study, a sample of 480 adult participants from different outpatient clinics were recruited in the study. The participant responded by self-report; the health belief model (HBM) scale, preventive behavior scale, subjective norms scale, the intention of planned behavior scale, and perceived control behavior scale were measured. The hypothesized causal path models were examined using SEM analysis.Results: The HBM had significant effects on perceived behavior control (β=0.60, P=0.001), the intended preventive behavior (β=0.32, P=0.001), and subjective norm (β=0.53, P=0.001). Subsequently, the intention of preventive behavior (β==0.39, P=0.001) and subjective norms (β=0.27, P=0.001) significantly affected the performance of preventive behaviors. The estimated fitting criteria showed that the hypothesized model fits relatively well.Conclusion: The health belief model with the integration of subjective norms, perceived control behavior and mediation by the intention of planned behavior in a pathway relationship explains well the preventive behavior of COVID-19. The findings present a deeper understanding of how integrating HBM and intended planned behavior enhances people's preventive behavior against COVID-19.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 1","pages":"115-123"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10921116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140093405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FNDC5 genetic polymorphism in patients with peripartum cardiomyopathy. 围产期心肌病患者的 FNDC5 基因多态性。

IF 1.4

Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.1.7

Ali Mohamad Altaher, Mohamed Eid, Hesham Moslem, Amal H Ali, Samar Mustafa, Amera Morad Foad

{"title":"FNDC5 genetic polymorphism in patients with peripartum cardiomyopathy.","authors":"Ali Mohamad Altaher, Mohamed Eid, Hesham Moslem, Amal H Ali, Samar Mustafa, Amera Morad Foad","doi":"10.22088/cjim.15.1.7","DOIUrl":"10.22088/cjim.15.1.7","url":null,"abstract":"Background: Late in pregnancy or soon after delivery, peripartum cardiomyopathy (PPCM) which is an uncommon type of cardiomyopathy, can develop. To assess the association between the level of irisin expression and (FNDC5) (rs3480) gene polymorphism with peripartum cardiomyopathy.Methods: This is a case control study included a thirty female patients with new-onset PPCM and sixty healthy females at the at the peripartum period in same time window for PPCM as a control. For each patient, comprehensive medical history was taken, full clinical assessment was done, ECHO., FNDC5 (rs3480) & Irisin assay.Results: The left ventricle end diastolic dimensions &left atrium diameters were statistically significant higher in patients' group than controls' group (P=0.000 for all), Also left ventricular ejection fraction (%) was statistically significant lower in patients than controls and as regards irisin, its Mean ±SD was lower in patient group than control group (8.44±1.1 vs 10.65±2.31) with (p <0.001) which is considered a significant difference statistically.Conclusion: Irisin level was lower in peripartum cardiomyopathic patients when compared with normal individuals and regarding its genotype, the homotype A/A was higher than homotype G/G.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 1","pages":"66-75"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10921118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140093453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of morphine, methadone, digoxin, and dronabinol poisoning during the years 2017 to 2019 in Ilam, Iran. 2017 - 2019年伊朗伊拉姆地区吗啡、美沙酮、地高辛和屈大麻酚中毒的评价

IF 1.4

Caspian Journal of Internal Medicine Pub Date : 2023-01-01 DOI: 10.22088/cjim.14.2.356

Kourosh Saki, Mahmoud Bahmani, Golnaz Zamanian, Naser Abbasi, Ali Aidy, Aliasghar Manouchehri, Sudip Kumar Mandal, Paramita Ganguly, Samira Shokri

{"title":"Evaluation of morphine, methadone, digoxin, and dronabinol poisoning during the years 2017 to 2019 in Ilam, Iran.","authors":"Kourosh Saki, Mahmoud Bahmani, Golnaz Zamanian, Naser Abbasi, Ali Aidy, Aliasghar Manouchehri, Sudip Kumar Mandal, Paramita Ganguly, Samira Shokri","doi":"10.22088/cjim.14.2.356","DOIUrl":"https://doi.org/10.22088/cjim.14.2.356","url":null,"abstract":"Background: Every year, drug poisoning is the most prevalent reason for referring patients to medical centers. This study aimed to evaluation of morphine, methadone, digoxin, and dronabinol poisoning in Shahid Mostafa Khomeini Hospital in Ilam.Methods: In this In this Cross-sectional study, patient samples suspected of morphine, methadone, digoxin, and dronabinol poisoning referred to the toxicology laboratory of Ilam University of Medical Sciences were analyzed using the HPLC method, and the results were analysed using SPSS software.Results: Results showed that the percentage of drug use is greater in men than in women. The highest percentage of morphine and methadone poisonings were detected in those under the age of 40, whereas the highest percentage of digoxin poisonings were recorded in those over the age of 80. As a result, the average age of digoxin users was substantially greater in men than in women. Methadone consumers showed significantly greater blood levels than others. In addition, there was a significant difference (P<0.01) in blood levels between men and women who used morphine.Conclusion: In general, it is important to understand the status of drug poisoning with drugs such as morphine, methadone, digoxin, and dronabinol, as well as the prognosis associated with the treatment process of such poisoning.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"14 2","pages":"356-364"},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9515777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does laparoscopic treatment of deep endometriosis improve sexual dysfunction. 腹腔镜治疗深层子宫内膜异位症能改善性功能障碍吗?

IF 1.4

Caspian Journal of Internal Medicine Pub Date : 2023-01-01 DOI: 10.22088/cjim.14.2.267

Abolfazl Mehdizadehkashi, Shahla Chaichian, Samaneh Rokhgireh, Kobra Tahermanesh, Shahla Mirgaloybayat, Reza Saadat Mostafavi, Sepideh Khodaverdi, Marziyeh Ajdary, Mahin Ahmadi Pishkuhi

{"title":"Does laparoscopic treatment of deep endometriosis improve sexual dysfunction.","authors":"Abolfazl Mehdizadehkashi, Shahla Chaichian, Samaneh Rokhgireh, Kobra Tahermanesh, Shahla Mirgaloybayat, Reza Saadat Mostafavi, Sepideh Khodaverdi, Marziyeh Ajdary, Mahin Ahmadi Pishkuhi","doi":"10.22088/cjim.14.2.267","DOIUrl":"https://doi.org/10.22088/cjim.14.2.267","url":null,"abstract":"Background: Endometriosis is one of the common gynecological problems during the reproductive years, affecting the quality of life, fertility, and sexual function of women. It is known that sexual dysfunction and quality of life are interrelated. Therefore, this study aimed to evaluate the effect of resection of endometriosis lesions via laparoscopic surgery on the improvement of sexual dysfunction in women with endometriosis.Methods: This clinical trial was performed on 30 patients with endometriosis. The Female Sexual Function Index, Endometriosis Health Profile-30, and Visual Analog Scale were completed for the patients before laparoscopic surgery and three, six, and 12 months after surgery. The results were examined and compared before and after the intervention using the ANOVA test.Results: The present results showed that the mean pain score of the patients (dysmenorrhea, dyspareunia, and pelvic pain) was significant after laparoscopic surgery (P<0.005). The female sexual function improved after laparoscopic surgery compared to the preoperative phase, and changes in the domains of psychological stimulation, humidity, and sexual orgasm were significant (P<0.005). Moreover, the female quality of life scores increased in all dimensions compared to the preoperative phase, although these improvements were not statistically significant.Conclusion: The present results revealed that laparoscopic surgery is an effective treatment, leading to a considerable improvement in female sexual function.","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"14 2","pages":"349-355"},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10201115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9517160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0