Caspian Journal of Internal Medicine最新文献

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Comparison between myocardial infarction with non-obstructive coronaries (MINOCA) and myocardial infarct patients with coronary artery disease (MI-CAD): A single-center retrospective cohort study. 冠状动脉无阻塞性心肌梗死(MINOCA)与冠状动脉疾病心肌梗死患者(MI-CAD)的比较:单中心回顾性队列研究。
IF 1.4
Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.1.12
Abbas Andishmand, Mahmood Emami Meybodi, Seyedeh Mahdieh Namayandeh, Hamid Reza Mohammadi, Mojtaba Andishmand, Mohammad Ali Zarbakhsh, Marzieh Azimi Zade
{"title":"Comparison between myocardial infarction with non-obstructive coronaries (MINOCA) and myocardial infarct patients with coronary artery disease (MI-CAD): A single-center retrospective cohort study.","authors":"Abbas Andishmand, Mahmood Emami Meybodi, Seyedeh Mahdieh Namayandeh, Hamid Reza Mohammadi, Mojtaba Andishmand, Mohammad Ali Zarbakhsh, Marzieh Azimi Zade","doi":"10.22088/cjim.15.1.12","DOIUrl":"10.22088/cjim.15.1.12","url":null,"abstract":"<p><strong>Background: </strong>The coronary angiography results in a group of patients with myocardial infarction (MI) are normal or near-normal; which is diagnosed as myocardial infarction with non-obstructive coronary arteries (MINOCA). This study aimed to compare the mortality rate and risk factors between MINOCA and myocardial infarction with obstructive coronary artery (MI-CAD).</p><p><strong>Methods: </strong>This retrospective cohort study was conducted from January 1, 2018, to December 31, 2019. A total of 679 patients admitted to Afshar Hospital in Yazd with a diagnosis of ST-elevation myocardial infarction (STEMI) from 2018-2019 who underwent primary Percutaneous Coronary Intervention (PCI) were enrolled in the study. Demographic, and clinical variables, ECG finding and one-year mortality, were extracted using MI registry data from the Yazd Cardiac Research Center.</p><p><strong>Results: </strong>The estimated frequency of MINOCA was 4.6%. Patients with MINOCA (47.14±6.2) were younger than patients with MI-CAD (57.61±9.1) (P <0.0001). MINOCA patients (47.4±9.47) had a considerably greater left ventricular ejection fraction (LVEF) than MI-CAD patients (43.5±6.8) (P =0.018). The majority site of MI in MINOCA patients was located in the non-anterior wall (p <0.0001). A comparison of MINOCA and MI-CAD patients' one-year mortality revealed no significant difference (P =0.07).</p><p><strong>Conclusion: </strong>The prevalence of patients with MINOCA in Yazd was similar to other communities. Although these patients probably do not have a better prognosis, despite being younger and having better LV systolic function and lower CAD risk factors.</p>","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 1","pages":"109-114"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10921117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140093399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of HIV, HBV, HCV, HPV and syphilis among female sex workers in Kurdistan, west of Iran. 伊朗西部库尔德斯坦女性性工作者中艾滋病毒、乙肝病毒、丙肝病毒、人乳头瘤病毒和梅毒的流行情况。
IF 1.4
Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.1.3
Somaye Mafakheri Bashmaq, Amjad Ahmadi, Behzad Mohsenpour, Khaled Rahmani, Modabber Arasteh, Narges Shams Alizadeh, Asrin Babahajian, Shoaib Advay, Asefeh Abbaszadeh
{"title":"Prevalence of HIV, HBV, HCV, HPV and syphilis among female sex workers in Kurdistan, west of Iran.","authors":"Somaye Mafakheri Bashmaq, Amjad Ahmadi, Behzad Mohsenpour, Khaled Rahmani, Modabber Arasteh, Narges Shams Alizadeh, Asrin Babahajian, Shoaib Advay, Asefeh Abbaszadeh","doi":"10.22088/cjim.15.1.3","DOIUrl":"10.22088/cjim.15.1.3","url":null,"abstract":"<p><strong>Background: </strong>Female sex workers (FSWs) in most societies run a high risk of health problems, including sexually transmitted infections (STIs) such as viral infections and syphilis. The present study examines the prevalence of viral infections and syphilis among FSWs.</p><p><strong>Methods: </strong>This cross-sectional study recruited 100 female sex workers (April 2019 to April 2020) who visited the Counseling Center for Behavioral Diseases or were selected via purposeful (snowball) sampling. A questionnaire (demographic information and STI risk factors) was completed in a face-to-face interview with the participants. Blood samples were then taken to test the markers for HBV, HCV Ab, HIV Ab, Rapid Plasma Reagin (RPR) for syphilis and a PCR was taken to test for HPV (in vaginal sex workers from the cervix and anal sex workers from the anal region). The data were analyzed in Stata 14.</p><p><strong>Results: </strong>Among 100 FSWs, 6 (6%) were infected with HIV, 1 (1%) with hepatitis B, and 2 (2%) were anti-HCV positive. 1 (1%) participant was suspected of having syphilis. Based on the PCR tests, 16 (16%) participants were infected with HPV. Moreover, 68 (68%) FSWs reported having unprotected sex.</p><p><strong>Conclusion: </strong>Due to the prevalence of viral infections and syphilis and unprotected sex in FSWs, immediate preventive measures are critical for this vulnerable group to control the transmission of these viral infections in society.</p>","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 1","pages":"38-45"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10921097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140093404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The glycosylated hemoglobin level and the severity of cardiovascular involvement in patients with the first episode of acute coronary syndrome. 首次急性冠状动脉综合征患者的糖化血红蛋白水平和心血管受累的严重程度。
IF 1.4
Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.1.4
Saman Khaleghi, Mohammad Ali Bayani, Naghmeh Ziaei, Mohammadtaghi Salehiomran, Soraya Khafri
{"title":"The glycosylated hemoglobin level and the severity of cardiovascular involvement in patients with the first episode of acute coronary syndrome.","authors":"Saman Khaleghi, Mohammad Ali Bayani, Naghmeh Ziaei, Mohammadtaghi Salehiomran, Soraya Khafri","doi":"10.22088/cjim.15.1.4","DOIUrl":"10.22088/cjim.15.1.4","url":null,"abstract":"<p><strong>Background: </strong>The current study was carried out aiming at investigating the relationship between glycosylated hemoglobin level and coronary atherosclerosis in patients with the first episode of acute coronary syndrome.</p><p><strong>Methods: </strong>This case-control study evaluated 450 patients with the first episode of acute coronary syndrome in Ayatollah Rouhani Hospital in Babol (Iran) from 2011 to 2018. Based on glycosylated hemoglobin, patients were divided into three groups of non-diabetic, pre-diabetic, and diabetic (n=150 in each group). Since SYNTAX score and Gensini score are employed to evaluate the extent of cardiovascular disease and predict CVD in patients with CAD over long-term follow-up, we calculated SYNTAX score and Gensini score based on angiographic results.</p><p><strong>Results: </strong>Concerning the factors related to the severity of cardiovascular involvement, the results revealed no significant difference between the diabetic and pre-diabetic groups in terms of the frequency of patients in terms of SYNTAX score, Gensini score, and the number of vessels involved (0.142 and 87, respectively, and P=0.102). However, this difference between the diabetic and non-diabetic groups, as well as between the pre-diabetic and non-diabetic groups was statistically significant (respectively for SYNTAX score, p< 0.001 and P=0.001; for Gensini score, P=0.013 and P=0.019; and for the number of vessels involved P=0.001and p<0.001).</p><p><strong>Conclusion: </strong>According to the findings of the current study, since there was no significant difference between diabetic and pre-diabetic patients in terms of the components indicating the severity of cardiovascular involvement, pre-diabetes itself may be associated with the severity of cardiovascular involvement as a predisposing factor.</p>","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 1","pages":"46-52"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10921112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140093409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deaddicta® for maintenance treatment of Opioid-dependence: A six-month follow-up. Deaddicta®用于阿片类药物依赖的维持治疗:六个月的随访
IF 0.8
Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.2.318
Abdolali Moosavyzadeh, Farzaneh Ghaffari, Mohammad Bagher Saberizafarghandi, Majid Talafi Noghani, Hossein Hassanpour, Fatemeh Emadi, Fatemeh Alijaniha, Zahra Bahaeddin, Leila Nasiri, Razieh Jafari Hajati, Mohsen Naseri
{"title":"Deaddicta® for maintenance treatment of Opioid-dependence: A six-month follow-up.","authors":"Abdolali Moosavyzadeh, Farzaneh Ghaffari, Mohammad Bagher Saberizafarghandi, Majid Talafi Noghani, Hossein Hassanpour, Fatemeh Emadi, Fatemeh Alijaniha, Zahra Bahaeddin, Leila Nasiri, Razieh Jafari Hajati, Mohsen Naseri","doi":"10.22088/cjim.15.2.318","DOIUrl":"10.22088/cjim.15.2.318","url":null,"abstract":"<p><strong>Background: </strong>Opioid dependence, is one of the world's most critical health problems. Deaddicta is a herbal product considered an effective treatment for opioid addiction. Deaddicta's efficacy in the maintenance treatment of patients with opioid use disorder has recently been demonstrated through a double-blind randomized controlled trial (RCT). This study aimed to evaluate the permanence of Deaddicta's efficacy six months after the end of the maintenance treatment for opioid dependence.</p><p><strong>Methods: </strong>This study was performed following the previous RCT on the maintenance treatment of opioid addicts. Out of 41 participants who completed the study for three months in the previous research, 15 from the intervention group (Deaddicta capsules, 1500 mg/day) returned for follow-up. They all previously fulfilled the DSM-IV criteria for addiction, were aged 18 to 65, and had discontinued Deaddicta for six months. The outcome measures included addiction severity, depression and anxiety levels, and craving score. The scores of each parameter were compared in three phases: before intervention; after three months of intervention; and six months after the end of the study.</p><p><strong>Results: </strong>Depression, anxiety, and craving scores decreased six months after the end of the previous study. This decrease was significant in the craving score (<i>P</i> = 0.011). No significant increase was observed in the frequency of use. The regression analysis showed a negative relationship between craving and the progression of phases.</p><p><strong>Conclusion: </strong>The Deaddicta product may have desirable and effective properties in decreasing temptation and, as a result, the maintenance treatment of opioid dependence.</p>","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 2","pages":"318-327"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11129080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of selenium on anti-Tg antibody in patients with autoimmune hypothyroidism: A randomized controlled trial. 硒对自身免疫性甲状腺功能减退症患者抗 Tg 抗体的影响:随机对照试验
IF 1.4
Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.2.340
Mina AkbariRad, Zahra Mazloum Khorasani, Behnam Beizae, Hossein Ayatollahi, Maryam Emadzadeh, Mehrdad Sarabi, Nikoo Saeedi, Negar Nekooei
{"title":"Effect of selenium on anti-Tg antibody in patients with autoimmune hypothyroidism: A randomized controlled trial.","authors":"Mina AkbariRad, Zahra Mazloum Khorasani, Behnam Beizae, Hossein Ayatollahi, Maryam Emadzadeh, Mehrdad Sarabi, Nikoo Saeedi, Negar Nekooei","doi":"10.22088/cjim.15.2.340","DOIUrl":"10.22088/cjim.15.2.340","url":null,"abstract":"<p><strong>Background: </strong>The current study intends to assess the impact of oral selenium intake on anti-Tg antibody in individuals with autoimmune hypothyroidism.</p><p><strong>Methods: </strong>In this double-blinded randomized controlled trial, two groups of 72 autoimmune hypothyroid patients were randomly assigned; one group received levothyroxine (LT4) and oral selenium and the other group was given placebo with LT4. Anti-Tg antibody, free T4, anti-TPO antibody, and TSH were identified in both groups before the treatment and also 3 months after treatment and analysis of data was done by SPSS software.</p><p><strong>Results: </strong>After the intervention, the average amount of anti-Tg antibody decreased in both of the groups, and this decrease was noticeably greater in the intervention group (P = 0.03). In the intervention group, the TSH level decreased after the intervention (p < 0.05), and the free T4 level increased after the intervention (p < 0.05); the changes in these two variables were statistically significant.</p><p><strong>Conclusion: </strong>Consumption of selenium, compared to placebo, in patients with autoimmune hypothyroidism drastically reduces the level of anti-Tg antibody, and it significantly increases the free T4 level. Also, there is a greater decrease in the level of TSH compared to the control group.</p>","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 2","pages":"340-346"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11129078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intracranial inflammatory pseudotumour related to IgG4: A very rare case. 与 IgG4 有关的颅内炎性假瘤:一个非常罕见的病例。
IF 1.4
Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.2.354
Ghassen Gader, Meissa Hamza, Ftima Jaziri, Ines Chelly, Ihsèn Zammel, Mouna Rkhami, Mohamed Badri
{"title":"Intracranial inflammatory pseudotumour related to IgG4: A very rare case.","authors":"Ghassen Gader, Meissa Hamza, Ftima Jaziri, Ines Chelly, Ihsèn Zammel, Mouna Rkhami, Mohamed Badri","doi":"10.22088/cjim.15.2.354","DOIUrl":"10.22088/cjim.15.2.354","url":null,"abstract":"<p><strong>Background: </strong>Intracranial inflammatory pseudotumours (IPT) are rare entities that frequently lead to misdiagnosis with malignant lesions. The identification of these lesions is difficult, but important to avoid inadvertent iatrogenicity and to adjust therapeutic protocols.</p><p><strong>Case presentation: </strong>We report the case of a 30-year-old man who presented a single tonic-clonic seizure. Brain imaging showed a right frontal lesion with intra and extra axial components. Facing the radiologic presentation, a brain tumor was suspected, thus the patient underwent surgery. Pathological exam concluded to a plasma cell granuloma. A whole-body CT-scan showed only a thoracic aortitis. Complete blood work studies came back negative. The patient was also tested for an array of antibodies among which antinuclear antibodies were positive (blood level superior to 1/100). CSF evaluation revealed clear fluid with normal glucose concentration, normal protein levels and lymphocytic pleocytosis. Finally, IgG-4 plasma levels were elevated which led to the diagnosis of an IgG4-RD. The patient was put under prednisolone with a favorable outcome.</p><p><strong>Conclusion: </strong>IPT have several etiologies, among which IgG4 related disease may be one of the less known as only 2 cases have previously been reported. Herein, we report a new case of a young man who presented for seizures related to an intracranial lesion of an IgG4 related disease. The challenge is to suspect such conditions to avoid unnecessary surgeries.</p>","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 2","pages":"354-359"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11129071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel therapeutic strategy for obesity through the gut microbiota-brain axis: A review article. 通过肠道微生物群-大脑轴治疗肥胖症的新策略:综述文章。
IF 1.4
Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.2.215
Romina Kardan, Jaber Hemmati, Mohsen Nazari, Amjad Ahmadi, Babak Asghari, Mehdi Azizi, Mansoor Khaledi, Mohammad Reza Arabestani
{"title":"Novel therapeutic strategy for obesity through the gut microbiota-brain axis: A review article.","authors":"Romina Kardan, Jaber Hemmati, Mohsen Nazari, Amjad Ahmadi, Babak Asghari, Mehdi Azizi, Mansoor Khaledi, Mohammad Reza Arabestani","doi":"10.22088/cjim.15.2.215","DOIUrl":"10.22088/cjim.15.2.215","url":null,"abstract":"<p><p><b>Background:</b> The interaction between commensal bacteria and the host is essential for health and the gut microbiota-brain axis plays a vital role in this regard. Obesity as a medical problem not only affect the health of the individuals, but also the economic and social aspects of communities. The presence of any dysbiosis in the composition of the gut microbiota disrupts in the gut microbiota-brain axis, which in turn leads to an increase in appetite and then obesity. Because common treatments for obesity have several drawbacks, the use of microbiota-based therapy in addition to treatment and prevention of obesity can have other numerous benefits for the individual. In this review, we intend to investigate the relationship between obesity and the gut microbiota-brain axis as well as novel treatment strategies based on this axis with an emphasis on gut microbiota.</p>","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 2","pages":"215-227"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11129059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and risk factors of gastroesophageal reflux disease symptoms in Mazandaran, North of Iran: A Tabari cohort study. 伊朗北部马赞达兰地区胃食管反流病症状的患病率和风险因素:塔巴里队列研究
IF 1.4
Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.2.280
Iradj Maleki, Samaneh Borhani, Mahmood Moosazadeh, Reza Alizadeh-Navaei
{"title":"Prevalence and risk factors of gastroesophageal reflux disease symptoms in Mazandaran, North of Iran: A Tabari cohort study.","authors":"Iradj Maleki, Samaneh Borhani, Mahmood Moosazadeh, Reza Alizadeh-Navaei","doi":"10.22088/cjim.15.2.280","DOIUrl":"10.22088/cjim.15.2.280","url":null,"abstract":"<p><strong>Background: </strong>Gastro-esophageal reflux disease (GERD) is a very common complaint. It is a major health concern and there is paucity of information about the epidemiology of the disease and its risk factors in Iran, especially Mazandaran province (North of Iran). This study aimed at investigating the prevalence of regurgitation and the factors associated with this condition in Tabari cohort study.</p><p><strong>Methods: </strong>This was a cross-sectional study that analyzed data from Tabari cohort study. Information including the presence and frequency of heartburn and regurgitation, demographic characteristics, socioeconomic status, occupational history, history of chronic illnesses, history of alcohol and cigarette consumption were recorded.</p><p><strong>Results: </strong>The prevalence of GERD symptoms were 27.6% (20.4% in men, and 32.4% in women, p=0.0001). The frequency of typical symptoms was significantly higher in women than that in men. The risk of developing GERD symptoms were 1.7 times higher in women (p=0.0001). The highest prevalence of GERD symptoms was found in urban areas (41.8%, p=0.0001), in people with low educational levels (48%, p=0.0001), and in participants with history of depression symptoms (36.2%, p=0.0001). The prevalence of GERD symptoms was significantly high in individuals with higher BMI (29.5%, p=0.006), greater waist to hip ratio (29.1%, p=0.0001, p=0.0001), and high waist circumference (31.7%, p=0.0001).</p><p><strong>Conclusion: </strong>This study showed gender, region of residence, educational level, and depression symptoms as the main risk factors for developing GERD symptoms.</p>","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 2","pages":"280-286"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11129062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thyroid diseases in children and adults with celiac disease: A cross-sectional study. 患有乳糜泻的儿童和成人的甲状腺疾病:一项横断面研究
IF 1.4
Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.2.307
Ramin Niknam, Heydar Baseri, Laleh Mahmoudi, Mohammad Reza Fattahi, Ebrahim Fallahzadeh Abarghooei, Ali Zamani
{"title":"Thyroid diseases in children and adults with celiac disease: A cross-sectional study.","authors":"Ramin Niknam, Heydar Baseri, Laleh Mahmoudi, Mohammad Reza Fattahi, Ebrahim Fallahzadeh Abarghooei, Ali Zamani","doi":"10.22088/cjim.15.2.307","DOIUrl":"10.22088/cjim.15.2.307","url":null,"abstract":"<p><strong>Background: </strong>There are few reports evaluating different factors, including the severity of duodenal histopathological findings and serological levels of celiac disease (CD), in increasing the probability of thyroid diseases (TD) in adults and children with CD, so, we designed this research.</p><p><strong>Methods: </strong>CD was defined as Marsh type 2 or higher in duodenal histopathology and serological levels of anti-transglutaminase antibodies (anti-tTG) equal to or greater than 18 IU/ml. To assess the likelihood of TD in CD patients, logistic regression analysis was employed.</p><p><strong>Results: </strong>538 patients were included in this study. Of these, 354 (65.8%) were females and 184 (34.2%) were males. 370 (68.8%) patients were children. Overall, 57 (10.6%) patients had TD, of which 49 (9.1%) had hypothyroidism and 8 (1.5%) had hyperthyroidism. Adults had a significantly higher probability of developing TD than children (OR 1.9; 95% CI 1.1-3.4; P = 0.03). The odds of developing TD were also significantly higher in patients with family marriage in parents (OR 2.3; 95% CI 1.1-4.7; P = 0.03). Other variables such as gastrointestinal symptoms, anti-tTG levels, and severity of Marsh classification did not exhibit a substantial rise in the likelihood of TD development.</p><p><strong>Conclusion: </strong>The study findings indicated that the likelihood of developing TD in CD patients can be linked to advancing age and having family marriage in parents, while there was no significant association observed with anti-tTG levels, severity of histological damage, and gastrointestinal symptoms.</p>","PeriodicalId":9646,"journal":{"name":"Caspian Journal of Internal Medicine","volume":"15 2","pages":"307-312"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11129079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Normal reference values for Tc-99m pertechnetate thyroid uptake in northern Iranian population: A single-center experience. 伊朗北部人群甲状腺摄取 Tc-99m 过硫酸盐的正常参考值:单中心经验。
IF 0.8
Caspian Journal of Internal Medicine Pub Date : 2024-01-01 DOI: 10.22088/cjim.15.3.459
Amir Gholami, Nima Armaghan, Hoda Shirafkan, Mehrangiz Amiri, Seyyed Hossein Mousavie Anijdan
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