{"title":"His dream became reality. In memory of professor Vladimír Vonka (1930-2025).","authors":"Milan Macek","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 6","pages":"282-284"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145793332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Shooting at the Faculty of Arts of Charles University and activation of the trauma plan at the First Surgical Clinic of the General Teaching Hospital.","authors":"Josef Kraus, Filip Burget","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Trauma Plan is a set of measures to mitigate the consequences of injury in emergencies and crisis situations. It was activated at the First Surgical Clinic of the General University Hospital in December 2023, on the day of the tragic shooting in the building of the Faculty of Arts of Charles University in Prague. Thanks to the practice activations, teams, premises and beds were prepared within 20 minutes without complications. An exceptional case was a gunshot wound that occurred at 350 meters (on the other bank of the Vltava River), the origin of which, however, the patient-foreigner was not aware of and was reported as a fracture of the femur after a fall while fleeing.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 3","pages":"90-93"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144858963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Newly discovered documents about J. E. Purkyně at the Anatomical Institute of the 1st Faculty of Medicine, Charles University.","authors":"Markéta Ivánková","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 6","pages":"273-278"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145793353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recommendations for the implementation of European Union regulations on the donation and use of human-derived substances.","authors":"Hana Konečná","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In July 2024, a European Union regulation on substances of human origin came into effect, which is to be implemented into the legislation of member states by August 2027. The fundamental ethical principle remains voluntary and unpaid donation, but the responsibility for addressing related ethical issues is left to the member states. Ethical topics that should be considered during implementation, such as methods of obtaining and compensating donors of substances of human origin, donor anonymity, and the content of informed consents, were addressed in our research project \"Quality and Sustainability of Body Part Donation Programs in the Czech Republic - TA ČR No. TL05000144\", which took place between 2021 and 2023.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 4","pages":"166-168"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Late-onset hypogonadism in men over 40 - how to use the updated EAU 2025 guidelines and new findings on the cardiovascular safety of testosterone therapy.","authors":"Marek Broul, Aneta Hujová","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Late-onset hypogonadism is a clinical syndrome defined by androgen-deficiency symptoms and persistently low testosterone; it affects roughly two to eight percent of European men aged 40-79 years and becomes more prevalent with advancing age, obesity and cardiometabolic comorbidities. The 2025 update of the European Association of Urology (EAU) guidelines sets a unified biochemical threshold of total testosterone below 12 nmol/L confirmed by two morning samples and emphasises baseline assessment of luteinizing hormone (LH), follicle-stimulating hormone (FSH), blood pressure and haematocrit before therapy. The large multicentre TRAVERSE trial showed that transdermal testosterone replacement does not increase major adverse cardiovascular events, yet revealed a mild rise in systolic blood pressure, a finding reflected in the latest US Food and Drug Administration (FDA) labelling changes. Building on this evidence, we propose a four-step algorithm encompassing precise diagnosis, judicious initiation of treatment, integrated management of cardiometabolic risk factors and personalised fertility preservation. Such an approach permits effective and safe management of symptomatic late-onset hypogonadism while mitigating long-term risks.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 4","pages":"150-155"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Alcohol-related liver disease.","authors":"Eva Mayerová","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Alcohol-related liver disease (ALD) represents a broad continuum of pathological conditions caused by excessive alcohol consumption - from simple steatosis through steatohepatitis and fibrosis to cirrhosis and its complications. The article summarizes the current view on this issue.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 7-8","pages":"299-305"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146092323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Health literacy in international recommendations and studies.","authors":"Alena Šteflová, Jan Dudra","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Health literacy means the ability to acquire, evaluate and apply health-related information. Health literacy affects motivation, health behavior, but also trust in health systems. For the development and improvement of health literacy in the European context, it is necessary to measure health literacy and compare it internationally.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 1","pages":"14-16"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144858947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preservation of antibiotics in Czech households and attitudes towards self-medication with antibiotics in the Czech population.","authors":"Jaroslava Hasmanová Marhánková, Ivan Petrúšek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Self-medication with antibiotics is one of the factors that can influence the process of antibiotic resistance. The results of a sample survey conducted by the Public Opinion Research Centre in the period June-August 2024 on a representative sample of the population of the Czech Republic aged 15 and over map the experience with self-medication with antibiotics and attitudes towards the use of antibiotics without medical consultation. At the same time, they provide an overview of the storage of unused antibiotics from previous treatment, which can be used for future self-medication. In 13.5 % of households in the Czech Republic, there are antibiotics that are not currently used, and these are mostly leftovers from previous treatment. Only 10.6% of respondents reported personal experience with self-medication with antibiotics without consulting a doctor. 18.4 % of respondents agree with the opinion that antibiotics can be administered without medical consultation in some cases. In international comparison, the Czech Republic is one of the countries with a lower proportion of the population storing unused antibiotics. These findings provide important information for public health policy formulation and education about the risks associated with antibiotic self-medication.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 1","pages":"9-13"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144858950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elena Tulupova, Eva Dohnalová, Jolana Kopsa Těšinová
{"title":"The role and position of intercultural workers in the provision of health care to refugees and migrants in the Czech Republic.","authors":"Elena Tulupova, Eva Dohnalová, Jolana Kopsa Těšinová","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Intercultural workers (also intercultural mediators, community interpreters) play a key role in overcoming language and cultural barriers between migrants and the healthcare systems of host countries. Based on international practice, the World Health Organization (WHO) strongly recommends the integration of intercultural mediators into healthcare systems throughout the European region to ensure equity, quality and sustainability of the healthcare system in an intercultural and multicultural environment. This article analyzes the emergence and status of the intercultural worker profession and its role in the process of providing various types of healthcare to refugees and migrants in the Czech Republic, focusing on legal, social and health aspects. It also describes the key challenges of integrating intercultural work into the existing healthcare and social system and suggests practical recommendations for improving cooperation between healthcare institutions and these key actors.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 1","pages":"25-31"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144858951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How to feed patients with obesity in intensive care?","authors":"Jarmila Křížová, Zuzana Kršáková","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In connection with the increasing prevalence of overweight and obesity, the number of these patients in intensive care units is increasing - current statistics indicate 20-30% of patients admitted in the obesity zone and 25% in the overweight zone. Nutritional goals and strategies for patients with obesity are one of the biggest challenges of modern nutritional care. They include a comprehensive diagnosis of malnutrition and the correct determination of energy and protein intake, for which it is possible to use formulas recommended by the European Society for Parenteral and Enteral Nutrition (ESPEN) or the American Society for Parenteral and Enteral Nutrition (ASPEN). The research focuses on the possibilities of immunonutrition and influencing the microbiota.</p>","PeriodicalId":9645,"journal":{"name":"Casopis lekaru ceskych","volume":"164 3","pages":"110-112"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144858961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}