Case Reports in Neurology最新文献_第9页

Unilateral C1 Posterior Arch Screw-C2 Laminar Screw Posterior Fixation for Vertebral Artery Preservation in Bow Hunter's Syndrome. 单侧C1后弓螺钉- c2椎板螺钉后路固定治疗弓形猎人综合征椎动脉保存。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000528058

Tatsuya Tanaka, Ren Fujiwara, Haruki Funao, Shigeto Ebata, Ryohei Sashida, Yu Hirokawa, Tomihiro Wakamiya, Yuhei Michiwaki, Kazuaki Shimoji, Eiichi Suehiro, Keisuke Onoda, Fumitaka Yamane, Ken Ishii, Masatou Kawashima, Akira Matsuno

{"title":"Unilateral C1 Posterior Arch Screw-C2 Laminar Screw Posterior Fixation for Vertebral Artery Preservation in Bow Hunter's Syndrome.","authors":"Tatsuya Tanaka, Ren Fujiwara, Haruki Funao, Shigeto Ebata, Ryohei Sashida, Yu Hirokawa, Tomihiro Wakamiya, Yuhei Michiwaki, Kazuaki Shimoji, Eiichi Suehiro, Keisuke Onoda, Fumitaka Yamane, Ken Ishii, Masatou Kawashima, Akira Matsuno","doi":"10.1159/000528058","DOIUrl":"https://doi.org/10.1159/000528058","url":null,"abstract":"Pedicle or lateral mass screws, which are usually used to fix atlantoaxial instability, increase the risk of vertebral artery (VA) injury in patients with bone or arterial anomalies or osteoporotic bone. Here, we report the use of a unilateral C1 posterior arch screw-C2 laminar screw posterior fixation with a contralateral C1 lateral mass screw for VA preservation in a patient with bow hunter's syndrome (BHS). A 65-year-old male presented with recurrent loss of consciousness in the right rotational and backward-bending head positions for 1 year. Cerebral angiography in the same head position showed that the left VA was disrupted at C1/2 and the right VA was hypoplastic. The patient was diagnosed with BHS. C1-2 posterior fixation and iliac bone grafting were performed. The left VA was on the dominant side, and the VA was in a high position; thus, a C1 posterior arch screw was selected for the left side, a C1 lateral mass screw was selected for the right side, and a C2 laminar screw with O-arm navigation and a C-arm was used to prevent arterial injury. Intraoperative findings revealed no VA injury, and postoperative computed tomography showed the screw at the planned site. In a patient with BHS, posterior fixation with a unilateral C1 posterior arch screw-C2 laminar screw prevented VA injury because the screw could be inserted while avoiding the VA.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"469-474"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6f/d8/crn-0014-0469.PMC9834639.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10590062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cetuximab-Induced Aseptic Meningitis in a Patient with Colorectal Cancer: A Case Report and Review of Literature. 西妥昔单抗致结直肠癌患者无菌性脑膜炎1例报告及文献复习。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000527075

Jakob Jäger, Maximilian Sprügel, Tamara Brunner, Martin Uhl, Stefan Schwab, Francesco Vitali, Axel Wein, Bastian Volbers

{"title":"Cetuximab-Induced Aseptic Meningitis in a Patient with Colorectal Cancer: A Case Report and Review of Literature.","authors":"Jakob Jäger, Maximilian Sprügel, Tamara Brunner, Martin Uhl, Stefan Schwab, Francesco Vitali, Axel Wein, Bastian Volbers","doi":"10.1159/000527075","DOIUrl":"https://doi.org/10.1159/000527075","url":null,"abstract":"Cetuximab is a chimeric IgG1 monoclonal antibody against epidermal growth factor receptor. It is approved by the European medical agency for the treatment of RAS wild-type metastatic colorectal cancer and metastatic squamous cell cancer of the head and neck. Few cases of aseptic meningitis, primarily associated with the first administration of cetuximab in patients with squamous cell cancer, have been reported. So far, there was only 1 case in a patient with metastatic colorectal cancer. We report on a 50-year-old Caucasian patient with metastatic rectum carcinoma who suffered from headache, fever, and neck stiffness 3 h after the first administration of cetuximab (400 mg/m2). CSF examination revealed an excessive pleocytosis with a white blood cell count of 2,433/µL. He was diagnosed with cetuximab-induced aseptic meningitis since clinical symptoms and CSF pleocytosis resolved within days, and further diagnostic workup revealed no infectious cause. Cetuximab-induced aseptic meningitis is a rare and severe drug reaction with predominance in treating squamous cell cancer of the head and neck. Clinical presentation and CSF findings suggest acute meningoencephalitis. In all reported cases, the course of the disease was benign and self-limited. Empiric antimicrobial and antiviral therapy are suggested until infectious causes can be ruled out. A lower dosage of cetuximab and a premedication including antihistamines and glucocorticosteroids may lower the risk of a re-occurrence if cetuximab therapy is continued.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"475-482"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/60/06/crn-0014-0475.PMC9834638.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10590065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Case Report: Three Case Reports of Rapidly Progressive Dementias and Narrative Review. 病例报告:快速进展性痴呆3例报告及叙述性回顾。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000525701

Carlos Andrés Clavijo, Ana María Portilla Buenaventura, Galo Santiago Benavides Albornoz, Juan José Muñoz Cabrera, María Camila Murillo Reyes, Alejandra Chauvez Gallego, Carlos Alberto Hurtado González, Sebastian Ospina Otalvaro, Carlos Steven Marmolejo Escobar, Karen Julieth Quebrada Mera, Paola Andrea Gutiérrez Lenis, Lina María Arango García, Armando Lucumí

{"title":"Case Report: Three Case Reports of Rapidly Progressive Dementias and Narrative Review.","authors":"Carlos Andrés Clavijo, Ana María Portilla Buenaventura, Galo Santiago Benavides Albornoz, Juan José Muñoz Cabrera, María Camila Murillo Reyes, Alejandra Chauvez Gallego, Carlos Alberto Hurtado González, Sebastian Ospina Otalvaro, Carlos Steven Marmolejo Escobar, Karen Julieth Quebrada Mera, Paola Andrea Gutiérrez Lenis, Lina María Arango García, Armando Lucumí","doi":"10.1159/000525701","DOIUrl":"https://doi.org/10.1159/000525701","url":null,"abstract":"Rapidly progressive dementia (RPD) is a heterogeneous group of diseases characterized by cognitive impairment and other neurological disorders developed in a short span of fewer than 2 years. Currently viewed as new and infrequent entities, most medical personnel have little understanding of it. Nevertheless, they significantly compromise many patients' quality of life. Here, we drive 3 clinical cases that evolve as RPD with different etiologies.Case 1: 70-year-old woman presented to the emergency with neuropsychiatric syndrome for 18 days. The researchers identified inflammatory cerebrospinal fluid (CSF), protein 14-3-3-positive T-tau protein, MRI: T2 and FLAIR hyperintensities in bilateral caudate nuclei with diffusion restriction, EEG shows a generalized periodic pattern with triphasic wave morphology.Case 2: 29-year-old man with cognitive impairment and faciobrachial dystonia seizure. The diagnosis was confirmed by achieving elevated antibodies against voltage-gated potassium channels.Case 3: A 49-year-old woman with encephalopathy and myoclonic seizures; EEG and MRI showed subtle changes. The patient also had a normal CSF but a positive CBA serologic NMDA-R antibody test. We described fundamental aspects of RPD to allow made differential diagnoses in patients with cognitive impairment and encephalopathy. Establishing an early and accurate diagnosis can benefit patients with RPD etiologies that are treatable and even reversible, decreasing in morbidity and mortality.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"441-455"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/26/6d/crn-0014-0441.PMC9830281.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10525859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Eteplirsen Use in a Boy with Duchenne Muscular Dystrophy and Sickle Cell Anemia. Eteplirsen在男孩杜氏肌营养不良和镰状细胞性贫血中的应用。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000527358

Gregory M Aiello, Michael Stephen Cartwright

引用次数: 1

Hope, Cure, and Adverse Effects in Immunotherapy: Atezolizumab-Associated Encephalitis in Metastatic Small Cell Lung Cancer - A Case Report and Literature Review. 免疫治疗的希望，治愈和不良反应:阿特唑单抗相关脑炎转移性小细胞肺癌- 1例报告和文献综述。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000526248

Eiman Y Ibrahim, Weige Charlie Zhao, Haritha Mopuru, Christopher Janowiecki, David J Regelmann

引用次数: 1

The Importance of F-Wave Patterns in a Patient with Cerebrovascular Disease Characterized by a Markedly Increased Tone of the Thenar Muscles. 以大鱼际肌张力明显增高为特征的脑血管病患者f波模式的重要性

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000526943

Toshiaki Suzuki, Yuki Fukumoto, Marina Todo, Makiko Tani, Sohei Yoshida

{"title":"The Importance of F-Wave Patterns in a Patient with Cerebrovascular Disease Characterized by a Markedly Increased Tone of the Thenar Muscles.","authors":"Toshiaki Suzuki, Yuki Fukumoto, Marina Todo, Makiko Tani, Sohei Yoshida","doi":"10.1159/000526943","DOIUrl":"https://doi.org/10.1159/000526943","url":null,"abstract":"F-waves are used to measure the excitability of spinal motor nerve function. This study aimed to investigate the F-wave patterns in a patient with cerebrovascular disease who had no voluntary movement of the hand, particularly the thumb, caused by a considerably increased tone of the thenar muscles. A patient with right hemiplegia caused by left cerebral hemorrhage (putamen) showed a considerably increased tone of the thumb flexors and no voluntary movements. F-waves were recorded from the affected thenar muscles with median nerve stimulation in the supine lying position during the first trial. Exercise therapy that included stretching of the affected thenar muscles was performed twice a week for 20 min for 8 months. Subsequent changes in the F-wave waveform were examined and considered as second trial. The latency and persistence of the F-wave and F-wave conduction velocity did not show any significant change between the two trials. Compared with the first trial, the F/M amplitude ratio in the second trial was increased. Following 8 months of exercise therapy, muscle tone improved slightly, and minimal voluntary movements of the affected thumb were noted. Since motor function of the affected thumb improved with exercise therapy but there was no improvement in F-wave data, it was determined that the main factor underlying the hypertonicity of the thenar muscles in this patient was more likely due to secondary muscle shortening than to spasticity. Unclear waves that possibly were F-waves were also observed approximately 20 ms after the appearance of the M-wave in the first trial but not in the second trial. Because exercise therapy showed muscle tone improvement and did not result in the appearance of unclear waves, F-wave patterns should be monitored for evaluating spasticity, which markedly increases muscle tone in patients with cerebrovascular disease.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"419-423"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e6/cf/crn-0014-0419.PMC9830284.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10532556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiple Dural Arteriovenous Fistulas as the Mystery of Rapidly Progressive Dementia with Bilateral Thalamic Lesions. 多发性硬脑膜动静脉瘘是伴有双侧丘脑病变的快速进展性痴呆的奥秘。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000527076

Yu Zhan, Murad Al-Nusaif, Chang Xu, Jiahao Li, Li Zhao, Feng Wang, Chunbo Dong

{"title":"Multiple Dural Arteriovenous Fistulas as the Mystery of Rapidly Progressive Dementia with Bilateral Thalamic Lesions.","authors":"Yu Zhan, Murad Al-Nusaif, Chang Xu, Jiahao Li, Li Zhao, Feng Wang, Chunbo Dong","doi":"10.1159/000527076","DOIUrl":"https://doi.org/10.1159/000527076","url":null,"abstract":"Dementia is a gradual and irreversible loss of higher mental function, particularly memory. Dural arteriovenous fistulas (DAVFs) are one of the rare causes of a rapid decline in cognitive function, which can be curable. DAVFs are pathological shunts between the dural artery and the dural venous sinus, dural vein, or cortical vein. Here, we present a case that initially manifested nausea and dizziness and developed rapidly progressive dementia caused by DAVFs in the left transverse sinus-sigmoid sinus junction area and the sinus confluence area, combined with cerebral venous sinus thrombosis. Moreover, our case has multiple DAVFs that cause bilateral thalamic lesions and rapidly progressive dementia called thalamic dementia, which is infrequent and often misdiagnosed. His symptoms have improved after receiving endovascular embolization treatment. In addition to presenting our case, we conducted a systemic literature review to summarize how familiarity with the manifestation and early diagnosis of bilateral thalamic lesions caused by DAVFs can lead to earlier and more effective therapy.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"404-412"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/08/48/crn-0014-0404.PMC9830287.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10532560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical Masks May Hide Neurological Diagnoses. 外科口罩可能隐藏神经学诊断。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000526716

Martin S Gizzi, Ryan J Mason, Andrew Amaranto

{"title":"Surgical Masks May Hide Neurological Diagnoses.","authors":"Martin S Gizzi, Ryan J Mason, Andrew Amaranto","doi":"10.1159/000526716","DOIUrl":"https://doi.org/10.1159/000526716","url":null,"abstract":"COVID-19 has disrupted the routine flow of patients through emergency departments (EDs) across the globe, including the need to consider COVID-19 for nearly all presenting complaints. The constraints of mask wearing and isolation have created inherent barriers to timely stroke care. We present a case that highlights one of the many ways in which the pandemic has negatively impacted the care of the non-COVID patient. A patient presented to the ED with a chief complaint of diffuse weakness and a new-onset cough on awakening. His daughter noted that he was slurring his words. An emergency medicine resident evaluated him, ordered laboratory studies, and decided to monitor the patient. The same resident later noted the patient veering to the left when walking, prompting a more detailed neurological examination. On removing the patient's facemask, a left lower facial weakness was evident. The resident called a Code Stroke roughly 50 min after the patient initially presented to the ED. The patient proved to have an acute infarct at the right thalamocapsular junction. Universal masking policies during the COVID-19 pandemic should not prevent the routine assessment of cranial nerve function for all patients presenting to an ED.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"377-380"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d0/69/crn-0014-0377.PMC9941768.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9321535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Usefulness of Swallowing Pressure Assessment in the Identification of Mild Pharyngeal Weakness of Myasthenia Gravis: A Case Report. 吞咽压力评估在重症肌无力轻度咽部无力诊断中的价值1例。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000526399

Kenjiro Kunieda, Yuichi Hayashi, Nobuaki Yoshikura, Tomohisa Ohno, Akio Kimura, Ichiro Fujishima, Takayoshi Shimohata

{"title":"The Usefulness of Swallowing Pressure Assessment in the Identification of Mild Pharyngeal Weakness of Myasthenia Gravis: A Case Report.","authors":"Kenjiro Kunieda, Yuichi Hayashi, Nobuaki Yoshikura, Tomohisa Ohno, Akio Kimura, Ichiro Fujishima, Takayoshi Shimohata","doi":"10.1159/000526399","DOIUrl":"https://doi.org/10.1159/000526399","url":null,"abstract":"Despite the clinical impact of dysphagia in myasthenia gravis (MG), a standard protocol for diagnosing dysphagia reliably has not yet been established. High-resolution manometry (HRM) provides precise information on pharyngeal pressure. We hypothesized that swallowing pressure assessment using HRM during the edrophonium chloride (EC) test could identify mild bulbar symptoms with no abnormalities on videoendoscopic (VE) and videofluorographic (VF) examination of swallowing, and we tested this hypothesis on a 72-year-old female patient diagnosed with ocular MG who developed slight pharyngeal discomfort over 3 months. The patient's ocular symptoms were stable with pyridostigmine medication. VE and VF revealed no abnormalities. The swallowing pressure along the pharynx was measured using HRM during the EC test. HRM parameters, including velopharyngeal contractile integral and meso-hypopharyngeal contractile integral, were evaluated. These parameters were assessed for three swallows using 3 mL of water. After EC injection, the values of the velopharyngeal contractile integral (78.0 ± 5.4 vs. 134.7 ± 1.3 mm Hg cm·s) and the meso-hypopharyngeal contractile integral were both higher (130.6 ± 1.5 vs. 284.2 ± 11.9 mm Hg cm·s) than those observed before EC injection. Chest computed tomography revealed a thymoma that had not been observed in previous examinations. The patient was diagnosed with thymoma-associated MG. Intravenous immunoglobulin therapy improved the mild dysphagia. We concluded that swallowing pressure assessment during the EC test may be helpful in identifying mild bulbar symptoms in patients with MG.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"372-376"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f3/2d/crn-0014-0372.PMC9941770.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9321536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Development of Pulmonary Edema after Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke Patient; Neurogenic or Non-Neurogenic? 重组组织型纤溶酶原激活剂对急性缺血性脑卒中患者肺水肿的影响神经源性还是非神经源性?

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Case Reports in Neurology Pub Date : 2022-08-30 eCollection Date: 2022-05-01 DOI: 10.1159/000526250

Ahmad Sulaiman Alwahdy, Ika Yulieta Margaretha Sihombing, Fitria Tahta Alfina, Niken Syahdian, Putri Nurbaeti, Annisa Futihandayani, Allifka Ramadhanti

引用次数: 0