Case Reports in Neurology最新文献_第8页

Punctate Enhancement of Bilateral Basal Ganglia in a Case of Epstein-Barr Virus Encephalitis. eb病毒脑炎的双侧基底神经节点状强化1例。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000526049

Takafumi Wada, Toru Yamamoto, Akihiko Ozaki

引用次数: 0

Rhabdomyolysis after COVID-19 Comirnaty Vaccination: A Case Report. COVID-19社区疫苗接种后横纹肌溶解1例报告

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000527599

Veerle J Ruijters, Marjon F G van der Meulen, Michael A van Es, Tessa Smit, Jessica E Hoogendijk

{"title":"Rhabdomyolysis after COVID-19 Comirnaty Vaccination: A Case Report.","authors":"Veerle J Ruijters, Marjon F G van der Meulen, Michael A van Es, Tessa Smit, Jessica E Hoogendijk","doi":"10.1159/000527599","DOIUrl":"https://doi.org/10.1159/000527599","url":null,"abstract":"Rhabdomyolysis is an acute disruption in skeletal muscle integrity, leading to the rapid release of 4 muscle contents into the bloodstream, such as creatine kinase (CK). It can have various causes, including infections. Throughout the pandemic, multiple cases of rhabdomyolysis following COVID-19 infections have been reported. However, rhabdomyolysis subsequent to COVID-19 vaccinations appears to be relatively rare. Here, we report such a case after a second COVID-19 Comirnaty (BioNTech/Pfizer) vaccination. Our patient developed rhabdomyolysis 1 day after the second Comirnaty vaccination with high creatine kinase (CK) levels, generalized weakness, and kidney failure. CK levels and muscle weakness resolved after treatment with intravenous fluids, but unfortunately, he remained hemodialysis dependent after discharge. To our knowledge, this is one of the first case reports describing a patient with rhabdomyolysis after a Comirnaty vaccination. However, as millions of people have received the Comirnaty vaccine, it is unclear whether the rhabdomyolysis in our patient is a rare side effect or an unrelated, coincidental event. Large observational studies are needed to elucidate the causality between the Comirnaty vaccination and rhabdomyolysis. Awareness is warranted in patients with myalgia and muscle weakness shortly after COVID-19 vaccination, in order to initiate treatment early and prevent life-threatening complications.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"429-432"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/95/f5/crn-0014-0429.PMC9830288.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10525860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Rapid Change in Shape of Unruptured Intracranial Aneurysm with Acute Perforating Infarction. 未破裂颅内动脉瘤伴急性穿孔性梗死形态的快速变化。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000527451

Tatsuya Tanaka, Hirofumi Goto, Nobuaki Momozaki, Eiichiro Honda

{"title":"Rapid Change in Shape of Unruptured Intracranial Aneurysm with Acute Perforating Infarction.","authors":"Tatsuya Tanaka, Hirofumi Goto, Nobuaki Momozaki, Eiichiro Honda","doi":"10.1159/000527451","DOIUrl":"https://doi.org/10.1159/000527451","url":null,"abstract":"Acute ischemic stroke is a rare complication resulting from an unruptured intracranial aneurysm (UIA). Ischemic stroke adjacent to the aneurysms is considered the risk of rupture of aneurysms. However, there is presently no consensus on the optimal strategy for the management of UIAs with ischemic stroke. A 27-year-old woman presented with sudden onset left hemiparesis. Acute infarction of the right basal ganglia and an aneurysm of the right middle cerebral artery were discovered on brain imaging. Antiplatelet therapy was used to treat her. The diagnosis revealed ischemic stroke caused by a thrombosed aneurysm due to the change in the shape of the aneurysm on day 4. The UIA clipping procedure was performed on day 21 due to the risk of subarachnoid hemorrhage (SAH). The findings of the surgery and indocyanine green imaging revealed a partially thrombosed aneurysm and occlusion of a perforating artery. As is well known, enlargement of aneurysm size indicates increasing rupture risk. In the present case, after ischemic events developed, magnetic resonance angiography revealed enlargement of the aneurysm. The findings of the surgery revealed possible pathogenic mechanisms were perforating artery occlusion due to local extension of the luminal thrombus. Clinicians should be aware of the risk of ischemic stroke due to luminal thrombosis of the UIA and SAH and should consider urgent treatment of the UIA even immediately after ischemic stroke.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"400-403"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5c/16/crn-0014-0400.PMC9830295.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10532557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resolution of Fulminant Idiopathic Intracranial Hypertension Treated with Acetazolamide. 乙酰唑胺治疗暴发性特发性颅内高压的疗效观察。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000527560

Ojas Srivastava, Jonathan A Micieli

{"title":"Resolution of Fulminant Idiopathic Intracranial Hypertension Treated with Acetazolamide.","authors":"Ojas Srivastava, Jonathan A Micieli","doi":"10.1159/000527560","DOIUrl":"https://doi.org/10.1159/000527560","url":null,"abstract":"Idiopathic intracranial hypertension (IIH) is a condition of elevated intracranial pressure commonly seen in obese women of childbearing age. Fulminant IIH is a rare subset of IIH that is characterized by rapidly progressive vision loss in less than 4 weeks, and typically requires surgical intervention for treatment. We describe a 36-year-old man with a 3-week history of acute onset vision loss and fulminant IIH in whom severe bilateral hemorrhagic optic disk edema was identified. There were also associated moderate visual field defects. Given the rapid onset of symptoms and severity of papilledema, surgical management was discussed but the patient had opted for medical management and close follow-up. He began oral acetazolamide, which was escalated to the maximal dose of 4 g and seen regularly with close follow-up. Four months after presentation, he was completely symptom free and the bilateral optic disk edema had resolved. His visual fields had also improved. We emphasize the importance of close follow-up in fulminant IIH and highlight that although most cases often require surgical intervention, some patients may show improvement with medical management only.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"424-428"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7b/be/crn-0014-0424.PMC9830306.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10532563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unilateral C1 Posterior Arch Screw-C2 Laminar Screw Posterior Fixation for Vertebral Artery Preservation in Bow Hunter's Syndrome. 单侧C1后弓螺钉- c2椎板螺钉后路固定治疗弓形猎人综合征椎动脉保存。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000528058

Tatsuya Tanaka, Ren Fujiwara, Haruki Funao, Shigeto Ebata, Ryohei Sashida, Yu Hirokawa, Tomihiro Wakamiya, Yuhei Michiwaki, Kazuaki Shimoji, Eiichi Suehiro, Keisuke Onoda, Fumitaka Yamane, Ken Ishii, Masatou Kawashima, Akira Matsuno

{"title":"Unilateral C1 Posterior Arch Screw-C2 Laminar Screw Posterior Fixation for Vertebral Artery Preservation in Bow Hunter's Syndrome.","authors":"Tatsuya Tanaka, Ren Fujiwara, Haruki Funao, Shigeto Ebata, Ryohei Sashida, Yu Hirokawa, Tomihiro Wakamiya, Yuhei Michiwaki, Kazuaki Shimoji, Eiichi Suehiro, Keisuke Onoda, Fumitaka Yamane, Ken Ishii, Masatou Kawashima, Akira Matsuno","doi":"10.1159/000528058","DOIUrl":"https://doi.org/10.1159/000528058","url":null,"abstract":"Pedicle or lateral mass screws, which are usually used to fix atlantoaxial instability, increase the risk of vertebral artery (VA) injury in patients with bone or arterial anomalies or osteoporotic bone. Here, we report the use of a unilateral C1 posterior arch screw-C2 laminar screw posterior fixation with a contralateral C1 lateral mass screw for VA preservation in a patient with bow hunter's syndrome (BHS). A 65-year-old male presented with recurrent loss of consciousness in the right rotational and backward-bending head positions for 1 year. Cerebral angiography in the same head position showed that the left VA was disrupted at C1/2 and the right VA was hypoplastic. The patient was diagnosed with BHS. C1-2 posterior fixation and iliac bone grafting were performed. The left VA was on the dominant side, and the VA was in a high position; thus, a C1 posterior arch screw was selected for the left side, a C1 lateral mass screw was selected for the right side, and a C2 laminar screw with O-arm navigation and a C-arm was used to prevent arterial injury. Intraoperative findings revealed no VA injury, and postoperative computed tomography showed the screw at the planned site. In a patient with BHS, posterior fixation with a unilateral C1 posterior arch screw-C2 laminar screw prevented VA injury because the screw could be inserted while avoiding the VA.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"469-474"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6f/d8/crn-0014-0469.PMC9834639.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10590062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cetuximab-Induced Aseptic Meningitis in a Patient with Colorectal Cancer: A Case Report and Review of Literature. 西妥昔单抗致结直肠癌患者无菌性脑膜炎1例报告及文献复习。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000527075

Jakob Jäger, Maximilian Sprügel, Tamara Brunner, Martin Uhl, Stefan Schwab, Francesco Vitali, Axel Wein, Bastian Volbers

{"title":"Cetuximab-Induced Aseptic Meningitis in a Patient with Colorectal Cancer: A Case Report and Review of Literature.","authors":"Jakob Jäger, Maximilian Sprügel, Tamara Brunner, Martin Uhl, Stefan Schwab, Francesco Vitali, Axel Wein, Bastian Volbers","doi":"10.1159/000527075","DOIUrl":"https://doi.org/10.1159/000527075","url":null,"abstract":"Cetuximab is a chimeric IgG1 monoclonal antibody against epidermal growth factor receptor. It is approved by the European medical agency for the treatment of RAS wild-type metastatic colorectal cancer and metastatic squamous cell cancer of the head and neck. Few cases of aseptic meningitis, primarily associated with the first administration of cetuximab in patients with squamous cell cancer, have been reported. So far, there was only 1 case in a patient with metastatic colorectal cancer. We report on a 50-year-old Caucasian patient with metastatic rectum carcinoma who suffered from headache, fever, and neck stiffness 3 h after the first administration of cetuximab (400 mg/m2). CSF examination revealed an excessive pleocytosis with a white blood cell count of 2,433/µL. He was diagnosed with cetuximab-induced aseptic meningitis since clinical symptoms and CSF pleocytosis resolved within days, and further diagnostic workup revealed no infectious cause. Cetuximab-induced aseptic meningitis is a rare and severe drug reaction with predominance in treating squamous cell cancer of the head and neck. Clinical presentation and CSF findings suggest acute meningoencephalitis. In all reported cases, the course of the disease was benign and self-limited. Empiric antimicrobial and antiviral therapy are suggested until infectious causes can be ruled out. A lower dosage of cetuximab and a premedication including antihistamines and glucocorticosteroids may lower the risk of a re-occurrence if cetuximab therapy is continued.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"475-482"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/60/06/crn-0014-0475.PMC9834638.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10590065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Case Report: Three Case Reports of Rapidly Progressive Dementias and Narrative Review. 病例报告:快速进展性痴呆3例报告及叙述性回顾。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000525701

Carlos Andrés Clavijo, Ana María Portilla Buenaventura, Galo Santiago Benavides Albornoz, Juan José Muñoz Cabrera, María Camila Murillo Reyes, Alejandra Chauvez Gallego, Carlos Alberto Hurtado González, Sebastian Ospina Otalvaro, Carlos Steven Marmolejo Escobar, Karen Julieth Quebrada Mera, Paola Andrea Gutiérrez Lenis, Lina María Arango García, Armando Lucumí

{"title":"Case Report: Three Case Reports of Rapidly Progressive Dementias and Narrative Review.","authors":"Carlos Andrés Clavijo, Ana María Portilla Buenaventura, Galo Santiago Benavides Albornoz, Juan José Muñoz Cabrera, María Camila Murillo Reyes, Alejandra Chauvez Gallego, Carlos Alberto Hurtado González, Sebastian Ospina Otalvaro, Carlos Steven Marmolejo Escobar, Karen Julieth Quebrada Mera, Paola Andrea Gutiérrez Lenis, Lina María Arango García, Armando Lucumí","doi":"10.1159/000525701","DOIUrl":"https://doi.org/10.1159/000525701","url":null,"abstract":"Rapidly progressive dementia (RPD) is a heterogeneous group of diseases characterized by cognitive impairment and other neurological disorders developed in a short span of fewer than 2 years. Currently viewed as new and infrequent entities, most medical personnel have little understanding of it. Nevertheless, they significantly compromise many patients' quality of life. Here, we drive 3 clinical cases that evolve as RPD with different etiologies.Case 1: 70-year-old woman presented to the emergency with neuropsychiatric syndrome for 18 days. The researchers identified inflammatory cerebrospinal fluid (CSF), protein 14-3-3-positive T-tau protein, MRI: T2 and FLAIR hyperintensities in bilateral caudate nuclei with diffusion restriction, EEG shows a generalized periodic pattern with triphasic wave morphology.Case 2: 29-year-old man with cognitive impairment and faciobrachial dystonia seizure. The diagnosis was confirmed by achieving elevated antibodies against voltage-gated potassium channels.Case 3: A 49-year-old woman with encephalopathy and myoclonic seizures; EEG and MRI showed subtle changes. The patient also had a normal CSF but a positive CBA serologic NMDA-R antibody test. We described fundamental aspects of RPD to allow made differential diagnoses in patients with cognitive impairment and encephalopathy. Establishing an early and accurate diagnosis can benefit patients with RPD etiologies that are treatable and even reversible, decreasing in morbidity and mortality.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"441-455"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/26/6d/crn-0014-0441.PMC9830281.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10525859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Eteplirsen Use in a Boy with Duchenne Muscular Dystrophy and Sickle Cell Anemia. Eteplirsen在男孩杜氏肌营养不良和镰状细胞性贫血中的应用。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000527358

Gregory M Aiello, Michael Stephen Cartwright

引用次数: 1

Hope, Cure, and Adverse Effects in Immunotherapy: Atezolizumab-Associated Encephalitis in Metastatic Small Cell Lung Cancer - A Case Report and Literature Review. 免疫治疗的希望，治愈和不良反应:阿特唑单抗相关脑炎转移性小细胞肺癌- 1例报告和文献综述。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000526248

Eiman Y Ibrahim, Weige Charlie Zhao, Haritha Mopuru, Christopher Janowiecki, David J Regelmann

引用次数: 1

The Importance of F-Wave Patterns in a Patient with Cerebrovascular Disease Characterized by a Markedly Increased Tone of the Thenar Muscles. 以大鱼际肌张力明显增高为特征的脑血管病患者f波模式的重要性

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000526943

Toshiaki Suzuki, Yuki Fukumoto, Marina Todo, Makiko Tani, Sohei Yoshida

{"title":"The Importance of F-Wave Patterns in a Patient with Cerebrovascular Disease Characterized by a Markedly Increased Tone of the Thenar Muscles.","authors":"Toshiaki Suzuki, Yuki Fukumoto, Marina Todo, Makiko Tani, Sohei Yoshida","doi":"10.1159/000526943","DOIUrl":"https://doi.org/10.1159/000526943","url":null,"abstract":"F-waves are used to measure the excitability of spinal motor nerve function. This study aimed to investigate the F-wave patterns in a patient with cerebrovascular disease who had no voluntary movement of the hand, particularly the thumb, caused by a considerably increased tone of the thenar muscles. A patient with right hemiplegia caused by left cerebral hemorrhage (putamen) showed a considerably increased tone of the thumb flexors and no voluntary movements. F-waves were recorded from the affected thenar muscles with median nerve stimulation in the supine lying position during the first trial. Exercise therapy that included stretching of the affected thenar muscles was performed twice a week for 20 min for 8 months. Subsequent changes in the F-wave waveform were examined and considered as second trial. The latency and persistence of the F-wave and F-wave conduction velocity did not show any significant change between the two trials. Compared with the first trial, the F/M amplitude ratio in the second trial was increased. Following 8 months of exercise therapy, muscle tone improved slightly, and minimal voluntary movements of the affected thumb were noted. Since motor function of the affected thumb improved with exercise therapy but there was no improvement in F-wave data, it was determined that the main factor underlying the hypertonicity of the thenar muscles in this patient was more likely due to secondary muscle shortening than to spasticity. Unclear waves that possibly were F-waves were also observed approximately 20 ms after the appearance of the M-wave in the first trial but not in the second trial. Because exercise therapy showed muscle tone improvement and did not result in the appearance of unclear waves, F-wave patterns should be monitored for evaluating spasticity, which markedly increases muscle tone in patients with cerebrovascular disease.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"419-423"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e6/cf/crn-0014-0419.PMC9830284.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10532556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0