Case Reports in Neurology最新文献_第7页

Efficacy of Intravenous Immunoglobulins against Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids: A Case Report. 静脉注射免疫球蛋白治疗慢性淋巴细胞炎伴桥桥血管周围增强对类固醇反应的疗效:1例报告。

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Case Reports in Neurology Pub Date : 2023-01-01 DOI: 10.1159/000529121

Takumi Tsuchida, Shigehisa Ura, Ichiro Yabe

{"title":"Efficacy of Intravenous Immunoglobulins against Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids: A Case Report.","authors":"Takumi Tsuchida, Shigehisa Ura, Ichiro Yabe","doi":"10.1159/000529121","DOIUrl":"https://doi.org/10.1159/000529121","url":null,"abstract":"Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disease of the central nervous system that predominantly affects the brainstem. Apart from corticosteroids, there are few reported treatment options for CLIPPERS, and there is no standard therapy. A 77-year-old man presented with diplopia that had persisted for 5 months. Dysarthria and numbness of the distal right upper extremity and right lips were also observed. Brain magnetic resonance imaging (MRI) revealed a hyperintense area around the brainstem. Symptoms were relieved immediately following intravenous methylprednisolone (IVMP) administration. However, after gradual tapering of oral prednisolone to 5 mg/day, the symptoms relapsed, and brain imaging revealed that the condition had worsened. Intravenous immunoglobulins (IVIg) were administered for recurrence, with no clinical improvement. After each IVMP treatment, the patient recovered promptly. Based on the patient's symptoms and characteristic MRI findings, exclusion of other diseases, and the significant efficacy of corticosteroids, he was diagnosed with CLIPPERS. There was no recurrence at a maintenance prednisolone dose of 8 mg/day. IVIg had a poor effect on the acute phase of CLIPPERS symptoms. Compared with other immunosuppressants, IVIg is less effective in suppressing the relapse of CLIPPERS.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"48-53"},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/65/b6/crn-2023-0015-0001-529121.PMC10018422.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9201076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acknowledgement to Reviewers 审稿人致谢

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Case Reports in Neurology Pub Date : 2022-12-16 DOI: 10.1159/000528563

引用次数: 0

Favorable Outcome with Intravenous Immunoglobulin Therapy in Late-Onset Anti-mGluR1 Encephalitis: A Case Report and Literature Review. 静脉注射免疫球蛋白治疗迟发性抗mglur1脑炎的良好结果:1例报告和文献复习。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000526632

Kento Sakashita, Katsuya Nishida, Yu Takenaka, Ichiro Yokota, Hiroshi Yamasaki, Keisuke Nishimoto, Kunihiko Kawamoto, Maki Mitani, Itaru Funakawa, Nobuaki Yoshikura, Akio Kimura, Takayoshi Shimohata, Naonobu Futamura

{"title":"Favorable Outcome with Intravenous Immunoglobulin Therapy in Late-Onset Anti-mGluR1 Encephalitis: A Case Report and Literature Review.","authors":"Kento Sakashita, Katsuya Nishida, Yu Takenaka, Ichiro Yokota, Hiroshi Yamasaki, Keisuke Nishimoto, Kunihiko Kawamoto, Maki Mitani, Itaru Funakawa, Nobuaki Yoshikura, Akio Kimura, Takayoshi Shimohata, Naonobu Futamura","doi":"10.1159/000526632","DOIUrl":"https://doi.org/10.1159/000526632","url":null,"abstract":"Anti-metabotropic glutamate receptor 1 (mGluR1) encephalitis is a rare autoimmune disorder manifesting with cerebellar syndrome. Patients with mGluR1 encephalitis have been treated with immunomodulatory therapies; however, little is known about the efficacy of this therapy. A 58-year-old Japanese woman presented with dizziness when walking and standing up. Symptoms persisted and the patient gradually deteriorated. The neurological examination revealed a broad-based gait, horizontal and slightly gaze-evoked nystagmus, noticeable head titubation, and truncal ataxia without limb ataxia. Magnetic resonance imaging was normal. The 123I-isopropyl-iodoamphetamine single-photon emission-computed tomography scans showed normal cerebellar perfusion. Based on a positive antibody test for anti-mGluR1, the patient was diagnosed with anti-mGluR1 encephalitis. She was treated with intravenous methylprednisolone and intravenous immunoglobulin (IVIg). Symptoms gradually improved over 1 month and almost disappeared after additional IVIg therapy. Anti-mGluR1 encephalitis is a rare disease, and effective treatment is unclear. In this case, a favorable outcome was obtained with immunomodulatory therapy, even though the neurological disability of the disease course is worse. We emphasize the importance of early diagnosis and therapeutic intervention, suspecting the disease on the basis of its characteristic symptoms.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"494-500"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8c/ad/crn-0014-0494.PMC9841793.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9114414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Donepezil-Induced Complex Multimodal Hallucinations: Two Cases and a Review of the Literature. 多奈哌齐致复杂多模态幻觉:两例及文献复习。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000526159

Federico Emanuele Pozzi, Lucio Tremolizzo, Carlo Ferrarese, Ildebrando Appollonio

引用次数: 1

Multiple Endovascular Treatments for Hemorrhagic Cerebral Proliferative Angiopathy: A Case Report. 出血性脑增生性血管病的多重血管内治疗1例。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000527559

Keijiro Shomura, Tomoya Kamide, Kouichi Misaki, Taishi Tsutsui, Iku Nambu, Naoyuki Uchiyama, Mitsutoshi Nakada

引用次数: 1

Serial Magnetic Resonance Imaging and Magnetic Resonance Angiographic Findings of Reversible Cerebral Vasoconstriction Syndrome Associated with Postpartum. 产后可逆性脑血管收缩综合征的磁共振成像和磁共振血管造影表现。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000527600

Yumiko Nakano, Shunya Fujiwara, Yoshio Omote, Motonori Takamiya, Hisashi Narai, Yasuhiro Manabe

引用次数: 0

Ischemic Optic Neuropathy Secondary to Varicella-Zoster Vasculitis Mimicking Giant Cell Arteritis: Case Report. 模拟巨细胞动脉炎的水痘带状疱疹血管炎继发缺血性视神经病变1例报告。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000527876

Alicia Rodriguez-Pla, Marie F Grill, Geoffrey P Fletcher, Marie A Di Nome

{"title":"Ischemic Optic Neuropathy Secondary to Varicella-Zoster Vasculitis Mimicking Giant Cell Arteritis: Case Report.","authors":"Alicia Rodriguez-Pla, Marie F Grill, Geoffrey P Fletcher, Marie A Di Nome","doi":"10.1159/000527876","DOIUrl":"https://doi.org/10.1159/000527876","url":null,"abstract":"Differentiating GCA from its many mimickers remains a challenge in the daily clinical practice, especially in patients presenting with unspecific manifestations. We present the case of an 82-year-old woman who presented with a 3-week history of left eye vision loss secondary to bilateral edema and hemorrhage of the optic discs. Despite negative bilateral temporal artery biopsies, the elevation of the inflammatory markers and brain MRA findings suggestive of temporal arteritis as well as stenosis of the basilar artery led us to initiate treatment with high-dose steroids. Inflammatory markers remained elevated despite high-dose steroids which prompted additional work leading to a diagnosis of varicella-zoster encephalitis. Steroid treatment was quickly tapered off and treatment with acyclovir resulted in the normalization of the acute phase reactants. The persistence of elevated inflammatory markers despite high-dose steroids should prompt additional work up for the search of an alternative diagnosis of GCA mimickers.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"483-490"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e7/7e/crn-0014-0483.PMC9834640.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10590060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vestibular Schwannoma Presenting as Acute Vertigo Mimicking Vestibular Neuritis. 前庭神经鞘瘤表现为急性眩晕模拟前庭神经炎。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000527989

Joon Yong Park, Chang-Hee Kim

引用次数: 0

Post Stroke Mirror Movements Preventing Performance of Bilateral Movements and Activities of Daily Living. 中风后镜像运动对双侧运动和日常生活活动的影响。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000525907

Hokuto Suzuki, Satoshi Yamamoto, Masahiro Wakatabi, Hiroyuki Ohtsuka

{"title":"Post Stroke Mirror Movements Preventing Performance of Bilateral Movements and Activities of Daily Living.","authors":"Hokuto Suzuki, Satoshi Yamamoto, Masahiro Wakatabi, Hiroyuki Ohtsuka","doi":"10.1159/000525907","DOIUrl":"https://doi.org/10.1159/000525907","url":null,"abstract":"Mirror movements (MMs) are involuntary synchronous movements of one limb during voluntary movements of the contralateral limb. Generally, MMs after stroke are observed in the unaffected hand during voluntary movements of the affected hand; MMs in the affected hand are comparatively rare. In previous studies, evaluation of MMs in the affected hand was performed using simple unilateral movement tasks, such as tapping or forceful repeated hand closure. However, the impact of MMs of the affected hand on functional tasks, such as activities of daily living (ADLs), has not been reported. We report the rare case of a patient with MMs of the affected hand due to atherothrombotic cerebral infarction of the right postcentral and precentral gyri. An 85-year-old Japanese man presented with left-sided hemiplegia and sensory impairment. MMs were observed in the left (affected) hand during many ADLs and could not be suppressed by the patient's will even when the examiner verbally instructed the patient to move only the unaffected hand. The patient was aware that his hand moved on its own, but he could not control it. The patient was trained on various types of bilateral coordinated motor exercises for 114 days after the MMs were first identified. However, this did not affect MM occurrence, and the MMs remained at the time of discharge. Future research is necessary to plan long-term interventions for MMs of the affected hand.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"389-396"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/21/77/crn-0014-0389.PMC9941781.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9321532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of Transcranial Direct Current Stimulation in Chronic Daily Headaches: An Experimental Single Case Report with a Novel Protocol. 经颅直流电刺激治疗慢性日常头痛的有效性:一项新方案的单例实验报告。

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Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000527021

Mohammad Dawood Rahimi, Hedieh Zargani, Karim Nikkhah

引用次数: 1