Case Reports in Neurology最新文献

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Hypertrophic Pachymeningitis with Persistent Intrathecal Inflammation Secondary to Neurosarcoidosis Treated with Intraventricular Chemotherapy: A Case Report. 脑室内化疗治疗继发于神经结节病的增生性厚膜脑膜炎伴持续性鞘内炎症1例。
IF 0.7
Case Reports in Neurology Pub Date : 2023-01-01 DOI: 10.1159/000531229
Ana Luísa de Almeida Marcelino, Simon Streit, Marie Alice Homeyer, Hans-Christian Bauknecht, Helena Radbruch, Klemens Ruprecht, Harald Prüss
{"title":"Hypertrophic Pachymeningitis with Persistent Intrathecal Inflammation Secondary to Neurosarcoidosis Treated with Intraventricular Chemotherapy: A Case Report.","authors":"Ana Luísa de Almeida Marcelino,&nbsp;Simon Streit,&nbsp;Marie Alice Homeyer,&nbsp;Hans-Christian Bauknecht,&nbsp;Helena Radbruch,&nbsp;Klemens Ruprecht,&nbsp;Harald Prüss","doi":"10.1159/000531229","DOIUrl":"https://doi.org/10.1159/000531229","url":null,"abstract":"<p><p>Hypertrophic pachymeningitis (HP) is a rare immune-mediated disease characterized by thickening of the dura mater with consecutive cranial neuropathy. While HP is usually treated with systemic immunotherapies, response to therapy is variable and may be limited by insufficient drug concentrations in the brain. We report on a 57-year-old patient with HP manifesting with vision and hearing loss who had sustained clinical progression despite various systemic immunotherapies. Intraventricular chemotherapy with methotrexate, cytarabine, and dexamethasone was initiated. We present clinical, imaging and cerebrospinal fluid (CSF) findings, including cytokine levels before and after intraventricular treatment: rapid decrease of cell count, lactate and profibrotic cytokine levels in the CSF following intraventricular chemotherapy was paralleled by a mild reduction of dura thickness in MRI. The already severely impaired visual acuity and hearing loss did not progress further. Treatment was complicated by exacerbation of previously subtle psychiatric symptoms. Follow-up was terminated after 6 months as the patient suffered from a fatal ischemic stroke. Autopsy revealed neurosarcoidosis as the underlying cause of HP. This case report suggests that intrathecal chemotherapy can reduce the inflammatory milieu in the CNS and should be considered for treatment-refractory HP before irreversible damage of cranial nerves has occurred.</p>","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"87-94"},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10201097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improved Osteoarthritis during Erenumab Treatment for Migraine: A Case Report. 治疗偏头痛时改善骨关节炎1例。
IF 0.7
Case Reports in Neurology Pub Date : 2023-01-01 DOI: 10.1159/000530138
Frederik Thal Jantzen, Rune Häckert Christensen, Basit Ali Chaudhry, Faisal Mohammad Amin
{"title":"Improved Osteoarthritis during Erenumab Treatment for Migraine: A Case Report.","authors":"Frederik Thal Jantzen,&nbsp;Rune Häckert Christensen,&nbsp;Basit Ali Chaudhry,&nbsp;Faisal Mohammad Amin","doi":"10.1159/000530138","DOIUrl":"https://doi.org/10.1159/000530138","url":null,"abstract":"<p><p>Antibodies blocking the calcitonin gene-related peptide have revolutionized episodic and chronic migraine treatment. However, their applicability to non-cephalic pain conditions, such as osteoarthritis, is yet unknown. Osteoarthritis remains a clinical challenge, associated with high disability and limited treatment options. Like migraine, neuropeptides including calcitonin gene-related peptides are involved in its pathophysiology. We present the first case of a patient: a 73-year-old female with osteoarthritis who received monthly treatment for her chronic migraine with 140 mg subcutaneous erenumab, a monoclonal antibody against the receptor of calcitonin gene-related peptide. Though the migraine was unresponsive, the patient's arthritic symptoms improved drastically during treatment period with erenumab; daily pain decreased from VAS 7 to 2, and walking distance doubled from 1,000 m to 2,000 m. The arthritic symptoms relapsed after discontinuation of erenumab. Erenumab could potentially have beneficial effects on symptoms of osteoarthritis. Future studies investigating these effects are warranted.</p>","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"95-99"},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6b/f6/crn-2023-0015-0001-530138.PMC10363275.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9867595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Autopsy Case of Elderly Onset Brainstem Acute Disseminated Encephalomyelitis. 老年发病脑干急性播散性脑脊髓炎尸检1例。
IF 0.7
Case Reports in Neurology Pub Date : 2023-01-01 DOI: 10.1159/000529180
Yasuyuki Takai, Shinsuke Tobisawa, Asuka Funai, Takashi Komori, Kazushi Takahashi
{"title":"An Autopsy Case of Elderly Onset Brainstem Acute Disseminated Encephalomyelitis.","authors":"Yasuyuki Takai,&nbsp;Shinsuke Tobisawa,&nbsp;Asuka Funai,&nbsp;Takashi Komori,&nbsp;Kazushi Takahashi","doi":"10.1159/000529180","DOIUrl":"https://doi.org/10.1159/000529180","url":null,"abstract":"<p><p>Acute disseminated encephalomyelitis (ADEM), which is a disease that causes multifocal inflammatory demyelination of the central nervous system, occurs predominantly in children and young adults. We report an autopsy case of an elderly man with brainstem ADEM that progressed over a period of about 3 months. An 82-year-old man developed disturbance of consciousness, dysphagia, and ataxic gait over a period of about 3 months. He was admitted to another hospital for aspiration pneumonia and recovered but was transferred to our hospital due to prolonged disturbance of consciousness. The patient was able to follow simple commands but had a tendency to somnolence. In addition to meningeal stimulation signs, the patient had left-dominant upper and lower limb ataxia and right-dominant limb spasticity. Brain FLAIR/T2-weighted imaging showed high-intensity lesions from the brainstem to the middle cerebellar peduncle bilaterally, medulla oblongata and upper cervical spinal cord, and T1-weighted imaging revealed contrast-enhanced lesions in the left middle cerebellar peduncle and cervical spinal cord. Although spinal fluid examination revealed elevated proteins, other laboratory tests indicated no evidence of infection, vasculitis, collagen diseases or tumors, and anti-ganglioside, anti-AQP4 and anti-MOG antibodies were negative. After admission, the patient again developed aspiration pneumonia, which progressed to acute respiratory distress syndrome, and he died on the 15th day of hospitalization. Autopsy findings indicated acute and subacute demyelination mainly in the brainstem and cerebellum, and perivascular lymphocyte and macrophage infiltration in the areas of demyelination. A postmortem diagnosis of ADEM was made based on the generally monophasic course of the disease and the absence of regenerating myelinated sheaths. There are very few reports of elderly patients with brainstem ADEM. ADEM should be considered as a differential diagnosis in patients with brainstem encephalitis.</p>","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"31-40"},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a9/28/crn-2023-0015-0001-529180.PMC9929651.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10756206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Olfactory Dysfunction, an Often Neglected Symptom of Hydrocephalus: Experience from a Case of Late-Onset Idiopathic Aqueductal Stenosis. 嗅觉功能障碍是脑积水常被忽视的症状:一例迟发性特发性导水管狭窄的经验。
IF 0.7
Case Reports in Neurology Pub Date : 2023-01-01 DOI: 10.1159/000529532
Naoya Yamazaki, Takafumi Hasegawa, Kensuke Ikeda, Ako Miyata, Shin-Ichiro Osawa, Kuniyasu Niizuma, Shigenori Kanno, Teiji Tominaga, Masashi Aoki
{"title":"Olfactory Dysfunction, an Often Neglected Symptom of Hydrocephalus: Experience from a Case of Late-Onset Idiopathic Aqueductal Stenosis.","authors":"Naoya Yamazaki,&nbsp;Takafumi Hasegawa,&nbsp;Kensuke Ikeda,&nbsp;Ako Miyata,&nbsp;Shin-Ichiro Osawa,&nbsp;Kuniyasu Niizuma,&nbsp;Shigenori Kanno,&nbsp;Teiji Tominaga,&nbsp;Masashi Aoki","doi":"10.1159/000529532","DOIUrl":"https://doi.org/10.1159/000529532","url":null,"abstract":"<p><p>Disturbance of smell is often accompanied with common neurodegenerative diseases such as Parkinson's and Alzheimer's diseases. In addition, patients with head trauma, intracranial tumors, and hydrocephalus can also develop olfactory dysfunction, and some of which can improve with treatment of the underlying disease. In clinical practice, few patients complain of smell disturbances, thus olfactory dysfunction is often overshadowed by visible motor symptoms. Herein, we report a case of late-onset idiopathic aqueductal stenosis, a rare form of adult-onset hydrocephalus in which olfactory dysfunction and gait disturbance was markedly improved after endoscopic ventriculostomy. This case report is expected to make more physicians aware that hydrocephalus can cause olfactory dysfunction and that it can be corrected postoperatively. Furthermore, in addition to motor and neuropsychological function, olfactory function test might be useful for functional assessment before and after surgical treatment of hydrocephalus.</p>","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"41-47"},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/83/f6/crn-2023-0015-0001-529532.PMC9978917.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9410778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebral Sinus Vein Thrombosis following Sneezing: Case Report. 打喷嚏后脑窦静脉血栓1例。
IF 0.7
Case Reports in Neurology Pub Date : 2023-01-01 DOI: 10.1159/000530812
Helal Nashef, Salo Haratz, Rom Mendel
{"title":"Cerebral Sinus Vein Thrombosis following Sneezing: Case Report.","authors":"Helal Nashef,&nbsp;Salo Haratz,&nbsp;Rom Mendel","doi":"10.1159/000530812","DOIUrl":"https://doi.org/10.1159/000530812","url":null,"abstract":"<p><p>Cerebral sinus vein thrombosis (CVT) is a relatively rare neurovascular entity, usually associated with acquired or genetic hypercoagulable states, and in many cases it remains idiopathic. Trauma is also associated with CVT among patients with major head or neck trauma, including penetrating injuries. However, CVT associated with acceleration trauma has only been described in few cases so far. We present an unusual case of a 19-year-old woman with no past medical history, admitted with an extensive CVT following sneezing. A thorough investigation did not reveal any other potential etiology or risk factor other than estrogen-containing oral contraceptives. The patient was treated with anticoagulation and improved clinically with complete recanalization on follow-up imaging. This case suggests acceleration trauma may be a potential factor of risk for CVT.</p>","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"108-112"},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9b/a9/crn-2023-0015-0001-530812.PMC10353342.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10221429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Intravenous Immunoglobulins against Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids: A Case Report. 静脉注射免疫球蛋白治疗慢性淋巴细胞炎伴桥桥血管周围增强对类固醇反应的疗效:1例报告。
IF 0.7
Case Reports in Neurology Pub Date : 2023-01-01 DOI: 10.1159/000529121
Takumi Tsuchida, Shigehisa Ura, Ichiro Yabe
{"title":"Efficacy of Intravenous Immunoglobulins against Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids: A Case Report.","authors":"Takumi Tsuchida,&nbsp;Shigehisa Ura,&nbsp;Ichiro Yabe","doi":"10.1159/000529121","DOIUrl":"https://doi.org/10.1159/000529121","url":null,"abstract":"<p><p>Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disease of the central nervous system that predominantly affects the brainstem. Apart from corticosteroids, there are few reported treatment options for CLIPPERS, and there is no standard therapy. A 77-year-old man presented with diplopia that had persisted for 5 months. Dysarthria and numbness of the distal right upper extremity and right lips were also observed. Brain magnetic resonance imaging (MRI) revealed a hyperintense area around the brainstem. Symptoms were relieved immediately following intravenous methylprednisolone (IVMP) administration. However, after gradual tapering of oral prednisolone to 5 mg/day, the symptoms relapsed, and brain imaging revealed that the condition had worsened. Intravenous immunoglobulins (IVIg) were administered for recurrence, with no clinical improvement. After each IVMP treatment, the patient recovered promptly. Based on the patient's symptoms and characteristic MRI findings, exclusion of other diseases, and the significant efficacy of corticosteroids, he was diagnosed with CLIPPERS. There was no recurrence at a maintenance prednisolone dose of 8 mg/day. IVIg had a poor effect on the acute phase of CLIPPERS symptoms. Compared with other immunosuppressants, IVIg is less effective in suppressing the relapse of CLIPPERS.</p>","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"48-53"},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/65/b6/crn-2023-0015-0001-529121.PMC10018422.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9201076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acknowledgement to Reviewers 审稿人致谢
IF 0.7
Case Reports in Neurology Pub Date : 2022-12-16 DOI: 10.1159/000528563
{"title":"Acknowledgement to Reviewers","authors":"","doi":"10.1159/000528563","DOIUrl":"https://doi.org/10.1159/000528563","url":null,"abstract":"<br />Case Rep Neurol 2022;14:491–493","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"80 4","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138508714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Favorable Outcome with Intravenous Immunoglobulin Therapy in Late-Onset Anti-mGluR1 Encephalitis: A Case Report and Literature Review. 静脉注射免疫球蛋白治疗迟发性抗mglur1脑炎的良好结果:1例报告和文献复习。
IF 0.7
Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000526632
Kento Sakashita, Katsuya Nishida, Yu Takenaka, Ichiro Yokota, Hiroshi Yamasaki, Keisuke Nishimoto, Kunihiko Kawamoto, Maki Mitani, Itaru Funakawa, Nobuaki Yoshikura, Akio Kimura, Takayoshi Shimohata, Naonobu Futamura
{"title":"Favorable Outcome with Intravenous Immunoglobulin Therapy in Late-Onset Anti-mGluR1 Encephalitis: A Case Report and Literature Review.","authors":"Kento Sakashita,&nbsp;Katsuya Nishida,&nbsp;Yu Takenaka,&nbsp;Ichiro Yokota,&nbsp;Hiroshi Yamasaki,&nbsp;Keisuke Nishimoto,&nbsp;Kunihiko Kawamoto,&nbsp;Maki Mitani,&nbsp;Itaru Funakawa,&nbsp;Nobuaki Yoshikura,&nbsp;Akio Kimura,&nbsp;Takayoshi Shimohata,&nbsp;Naonobu Futamura","doi":"10.1159/000526632","DOIUrl":"https://doi.org/10.1159/000526632","url":null,"abstract":"<p><p>Anti-metabotropic glutamate receptor 1 (mGluR1) encephalitis is a rare autoimmune disorder manifesting with cerebellar syndrome. Patients with mGluR1 encephalitis have been treated with immunomodulatory therapies; however, little is known about the efficacy of this therapy. A 58-year-old Japanese woman presented with dizziness when walking and standing up. Symptoms persisted and the patient gradually deteriorated. The neurological examination revealed a broad-based gait, horizontal and slightly gaze-evoked nystagmus, noticeable head titubation, and truncal ataxia without limb ataxia. Magnetic resonance imaging was normal. The <sup>123</sup>I-isopropyl-iodoamphetamine single-photon emission-computed tomography scans showed normal cerebellar perfusion. Based on a positive antibody test for anti-mGluR1, the patient was diagnosed with anti-mGluR1 encephalitis. She was treated with intravenous methylprednisolone and intravenous immunoglobulin (IVIg). Symptoms gradually improved over 1 month and almost disappeared after additional IVIg therapy. Anti-mGluR1 encephalitis is a rare disease, and effective treatment is unclear. In this case, a favorable outcome was obtained with immunomodulatory therapy, even though the neurological disability of the disease course is worse. We emphasize the importance of early diagnosis and therapeutic intervention, suspecting the disease on the basis of its characteristic symptoms.</p>","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"494-500"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8c/ad/crn-0014-0494.PMC9841793.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9114414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Donepezil-Induced Complex Multimodal Hallucinations: Two Cases and a Review of the Literature. 多奈哌齐致复杂多模态幻觉:两例及文献复习。
IF 0.7
Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000526159
Federico Emanuele Pozzi, Lucio Tremolizzo, Carlo Ferrarese, Ildebrando Appollonio
{"title":"Donepezil-Induced Complex Multimodal Hallucinations: Two Cases and a Review of the Literature.","authors":"Federico Emanuele Pozzi,&nbsp;Lucio Tremolizzo,&nbsp;Carlo Ferrarese,&nbsp;Ildebrando Appollonio","doi":"10.1159/000526159","DOIUrl":"https://doi.org/10.1159/000526159","url":null,"abstract":"<p><p>Hallucinations are common in neurodegenerative dementias, being present in a significant proportion of patients. Most of the available studies show that acetylcholinesterase inhibitors may be beneficial in preventing and treating hallucinations in patients with neurodegenerative and even psychiatric disorders, even though there are reports that they might also develop as an adverse effect of such therapy. However, a clear causal relationship for the latter association was not previously established. Here we describe 2 cases of patients treated with donepezil who developed complex multimodal hallucinations, which could be causally linked to the drug by means of a challenge-dechallenge (and rechallenge in one case) paradigm. We also provide a narrative review of the literature regarding donepezil and hallucinations and propose a hypothesis to explain the occurrence of this phenomenon.</p>","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"359-365"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ae/63/crn-0014-0359.PMC9941780.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9321537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Multiple Endovascular Treatments for Hemorrhagic Cerebral Proliferative Angiopathy: A Case Report. 出血性脑增生性血管病的多重血管内治疗1例。
IF 0.7
Case Reports in Neurology Pub Date : 2022-09-01 DOI: 10.1159/000527559
Keijiro Shomura, Tomoya Kamide, Kouichi Misaki, Taishi Tsutsui, Iku Nambu, Naoyuki Uchiyama, Mitsutoshi Nakada
{"title":"Multiple Endovascular Treatments for Hemorrhagic Cerebral Proliferative Angiopathy: A Case Report.","authors":"Keijiro Shomura,&nbsp;Tomoya Kamide,&nbsp;Kouichi Misaki,&nbsp;Taishi Tsutsui,&nbsp;Iku Nambu,&nbsp;Naoyuki Uchiyama,&nbsp;Mitsutoshi Nakada","doi":"10.1159/000527559","DOIUrl":"https://doi.org/10.1159/000527559","url":null,"abstract":"<p><p>Cerebral proliferative angiopathy (CPA) is a rare vascular abnormality characterized by transdural supply, stenoses of feeding arteries, and intermingled normal brain parenchyma in abnormal vessels. CPA is often regarded as a separate entity from \"classical\" brain arteriovenous malformations in angioarchitecture, natural history, clinical presentation, and treatment. Bleeding from CPA is uncommon, but once bleeding occurs, the risk of rebleeding is high. Herein, we describe a case of cerebral hemorrhage caused by CPA. We performed two different endovascular treatments: partial embolization with glue for a ruptured aneurysm and coil embolization for an unruptured growing aneurysm. To our knowledge, this is the first report of serial endovascular treatments for hemorrhagic CPA that included a ruptured aneurysm and a growing unruptured aneurysm.</p>","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"14 3","pages":"433-440"},"PeriodicalIF":0.7,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/81/2e/crn-0014-0433.PMC9830309.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10532559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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