Oriana E Belli, Jonica Campolo, Paola Vallerio, Francesco Musca, Antonella Moreo, Alessandro Maloberti, Marina Parolini, Luca Bonacchini, Gianpaola Monti, Andrea De Gasperi, Roberto Fumagalli, Cristina Giannattasio
{"title":"Biochemical but not imaging parameters are predictive of outcome in septic shock: a pilot study.","authors":"Oriana E Belli, Jonica Campolo, Paola Vallerio, Francesco Musca, Antonella Moreo, Alessandro Maloberti, Marina Parolini, Luca Bonacchini, Gianpaola Monti, Andrea De Gasperi, Roberto Fumagalli, Cristina Giannattasio","doi":"10.1186/s12947-022-00276-3","DOIUrl":"https://doi.org/10.1186/s12947-022-00276-3","url":null,"abstract":"<p><strong>Background: </strong>Septic shock is a severe form of sepsis marked by hypotension with an ominous outcome despite the introduction of modern intensive care. The aim of the present study is to obtain a panel with biomarkers, echocardiographic and vascular parameters to better risk stratify patients and identify those at higher risk of ominous outcome.</p><p><strong>Methods: </strong>Between May 2013 and April 2016, 35 consecutive patients admitted at the Intensive Care Unit (ICU) of ASST Great Metropolitan Hospital Niguarda with the diagnosis of severe sepsis or septic shock were enrolled. All patients underwent rest echocardiography and several circulating biomarkers of myocardial damage or oxidative stress.</p><p><strong>Results: </strong>The multivariate Cox's proportional hazard model showed that the only independent prognostic predictor for 30-day mortality was the angiopoietin-2, (HR 1.017, 95% CI 1.000-1.034; P = 0.049). An angiopoietin-2 concentrations ≥ of 33,418 pg/mL was identified as the optimal threshold for the discrimination between survivors and non survivors at the time of admission in ICU, with a sensitivity of 80% and a specificity of 68%.</p><p><strong>Conclusions: </strong>Septic shock has a poor in-hospital outcome even when the best of care is implemented. Among the biochemical parameters angiopoietin was able to identify patients at risk of death. The lowest the value at admission, the highest the risk of in-hospital death. No echocardiographic nor vascular parameter was able to predict outcome in this setting.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":"6"},"PeriodicalIF":1.9,"publicationDate":"2022-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40325514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
U. Yildirim, M. Akçay, Metin Çoksevim, E. Turkmen, O. Gulel
{"title":"Comparison of left atrial deformation parameters between renal transplant and hemodialysis patients","authors":"U. Yildirim, M. Akçay, Metin Çoksevim, E. Turkmen, O. Gulel","doi":"10.1186/s12947-022-00275-4","DOIUrl":"https://doi.org/10.1186/s12947-022-00275-4","url":null,"abstract":"","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44823924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suyeon Park, Hye-Sung Won, Rina Kim, Mijin Kim, Jeong Jin Yu, Chun Soo Park, Tae-Jin Yun, Yewon Jung, Usamah Al Harbi, Mi-Young Lee
{"title":"Fetal cardiac parameters for predicting postnatal operation type of fetuses with tetralogy of Fallot.","authors":"Suyeon Park, Hye-Sung Won, Rina Kim, Mijin Kim, Jeong Jin Yu, Chun Soo Park, Tae-Jin Yun, Yewon Jung, Usamah Al Harbi, Mi-Young Lee","doi":"10.1186/s12947-022-00274-5","DOIUrl":"https://doi.org/10.1186/s12947-022-00274-5","url":null,"abstract":"<p><strong>Background: </strong>To assess fetal cardiac parameters predictive of postnatal operation type in fetuses with tetralogy of Fallot (TOF).</p><p><strong>Methods: </strong>Echocardiographic data obtained in the second and third trimesters were retrospectively reviewed for fetuses diagnosed with TOF between 2014 and 2018 at Asan Medical Center. The following fetal cardiac parameters were analyzed: 1) pulmonary valve annulus (PVA) z-score, 2) right pulmonary artery (RPA) z-score, 3) aortic valve annulus (AVA) z-score, 4) pulmonary valve peak systolic velocity (PV-PSV), 5) PVA/AVA ratio, and 6) RPA/descending aorta (DAo) ratio. These cardiac parameters were compared between a primary corrective surgery group and a palliative shunt operation followed by complete repair group.</p><p><strong>Results: </strong>A total of 100 fetuses with TOF were included. Only one neonatal death occurred. Ninety patients underwent primary corrective surgery and 10 neonates underwent a multistage surgery. The PVA z-score, RPA z-score, and RPA/DAo ratio measured in the second trimester and the PVA z-score, RPA z-score, and PVA/AVA raio measured in the third trimester were significantly lower in the multistage surgery group, while the PV-PSV as measured in both trimesters were significantly higher in the multistage surgery group.</p><p><strong>Conclusion: </strong>Fetal cardiac parameters are useful for predicting the operation type necessary for neonates with TOF.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":"4"},"PeriodicalIF":1.9,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39941678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Doaa Aly, Nitin Madan, Laura Kuzava, Alison Samrany, Anitha Parthiban
{"title":"Comprehensive evaluation of left ventricular deformation using speckle tracking echocardiography in normal children: comparison of three-dimensional and two-dimensional approaches.","authors":"Doaa Aly, Nitin Madan, Laura Kuzava, Alison Samrany, Anitha Parthiban","doi":"10.1186/s12947-022-00273-6","DOIUrl":"https://doi.org/10.1186/s12947-022-00273-6","url":null,"abstract":"<p><strong>Background: </strong>Three-dimensional (3D) speckle tracking echocardiography (STE) can overcome some of the inherent limitations of two-dimensional (2D) STE; however, clinical experience is lacking. We aimed to assess and compare the feasibility, agreement, and reproducibility of left ventricular (LV) global longitudinal (GLS), and regional strain by 3D vs 2D STE in normal children.</p><p><strong>Methods: </strong>Healthy pediatric subjects (n = 105, age mean = 11.2 ± 5.5 years) were prospectively enrolled. Three-dimensional and 2D LV GLS, as well as regional strain in 16 myocardial segments were quantified. Bland Altman analysis, intra- class correlation coefficients (ICC), percent error and linear regression were used for agreement and correlation between the two techniques. Analysis and acquisition times were compared. Inter- and intra-observer reproducibility was assessed in 20 studies.</p><p><strong>Results: </strong>There was good to excellent agreement for 2D and 3D global longitudinal strain (ICC =0.82) and modest agreement for regional strain (ICC range 0.43-0.71). Both methods had high feasibility (88.6% for 2D vs 85.7% for 3D, p = 0.21), although 3D STE required significantly shorter acquisition and analysis time than 2D STE (acquisition time 1 ± 1.2 mins vs 2.4 ± 1 mins; p = 0.03, analysis time = 3.3 ± 1 mins vs 8.2 ± 2.5 mins; p = 0.001, respectively). Inter and intra-observer reproducibility was excellent for GLS by the two techniques (ICC = 0.78-0.93) but moderate to poor for regional strain (ICC = 0.21-0.64).</p><p><strong>Conclusion: </strong>Three-dimensional global LV strain is as feasible and reproducible as 2D strain, with good agreement yet significantly more efficient acquisition and analysis. Regional strain is less concordant and 2D and 3D values should not be used interchangeably. 3D LV GLS may represent a viable alternative in evaluation of LV deformation in pediatric subjects.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":"3"},"PeriodicalIF":1.9,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39865006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jing Han, Xi Yang, Wei Xu, Ronghua Jin, Weiyuan Liu, Lei Ding, Sha Meng, Yuan Zhang, Jin Li, Ying Zheng, Haowen Li, Fankun Meng
{"title":"Pilot study on the value of echocardiography combined with lung ultrasound to evaluate COVID-19 pneumonia.","authors":"Jing Han, Xi Yang, Wei Xu, Ronghua Jin, Weiyuan Liu, Lei Ding, Sha Meng, Yuan Zhang, Jin Li, Ying Zheng, Haowen Li, Fankun Meng","doi":"10.1186/s12947-021-00271-0","DOIUrl":"https://doi.org/10.1186/s12947-021-00271-0","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the relationship between echocardiography results and lung ultrasound score (LUS) in coronavirus disease 2019 (COVID-19) pneumonia patients and evaluate the impact of the combined application of these techniques in the evaluation of COVID-19 pneumonia.</p><p><strong>Methods: </strong>Hospitalized COVID-19 pneumonia patients who underwent daily lung ultrasound and echocardiography were included in this study. Patients with tricuspid regurgitation within three days of admission were enrolled. Moreover, the correlation and differences between their pulmonary artery pressure (PAP) and LUS on days 3, 8, and 13 were analyzed. The inner diameter of the pulmonary artery root as well as the size of the atria and ventricles were also considered.</p><p><strong>Results: </strong>The PAP on days 3, 8, and 13 of hospitalization was positively correlated with the LUS (r = 0.448, p = 0.003; r = 0.738, p < 0.001; r = 0.325, p = 0.036, respectively). On day 8, the values of both PAP and LUS were higher than on days 3 and 13 (p < 0.01). Similarly, PAP and LUS were significantly increased in 92.9% (39/42) and 90.5% (38/42) of patients, respectively, and at least one of these two values was positive in 97.6% (41/42) of cases. The inner diameters of the right atrium, right ventricle, and pulmonary artery also differed significantly from their corresponding values on days 3 and 13 (p < 0.05).</p><p><strong>Conclusions: </strong>PAP is positively correlated with LUS in COVID-19 pneumonia. The two values could be combined for a more precise assessment of disease progression and recovery status.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":"2"},"PeriodicalIF":1.9,"publicationDate":"2022-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39832969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vivien Vértes, Adél Porpáczy, Ágnes Nógrádi, Margit Tőkés-Füzesi, Máté Hajdu, László Czirják, András Komócsi, Réka Faludi
{"title":"Galectin-3 and sST2: associations to the echocardiographic markers of the myocardial mechanics in systemic sclerosis - a pilot study.","authors":"Vivien Vértes, Adél Porpáczy, Ágnes Nógrádi, Margit Tőkés-Füzesi, Máté Hajdu, László Czirják, András Komócsi, Réka Faludi","doi":"10.1186/s12947-022-00272-7","DOIUrl":"https://doi.org/10.1186/s12947-022-00272-7","url":null,"abstract":"<p><strong>Background: </strong>Progressive cardiac fibrosis is the central aspect of the myocardial involvement in systemic sclerosis (SSc). We hypothesized that circulating biomarkers of the cardiac fibrosis may be useful in the early diagnosis of the cardiac manifestation in this disease. Thus, we investigated the potential correlations between the levels of galectin-3, soluble suppression of tumorigenicity-2 (sST2) and the echocardiographic markers of the myocardial mechanics in SSc patients.</p><p><strong>Methods: </strong>Forty patients (57.3 ± 13.7 years, 36 female) were investigated. In addition to the conventional echocardiography, tissue Doppler and speckle tracking-derived strain techniques were used to assess the function of both ventricles and atria. To estimate the correlations between galectin-3 and sST2 levels and the echocardiographic variables, partial correlation method was used with age as correcting factor.</p><p><strong>Results: </strong>In age adjusted analysis galectin-3 level showed significant correlation with left ventricular global longitudinal strain (r = 0.460, p = 0.005); grade of left ventricular diastolic dysfunction (r = 0.394, p = 0.013); septal e' (r = - 0.369, p = 0.021); septal E/e' (r = 0.380, p = 0.017) and with the grade of mitral regurgitation (r = 0.323, p = 0.048). No significant correlation was found between sST2 levels and the echocardiographic variables.</p><p><strong>Conclusions: </strong>Galectin-3 levels, but not sST2 levels show significant correlation with the parameters of the left ventricular systolic and diastolic function. Galectin-3 may be a useful biomarker for the screening and early diagnosis of SSc patients with cardiac involvement.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":"20 1","pages":"1"},"PeriodicalIF":1.9,"publicationDate":"2022-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8764793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10670210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Changsheng Ma, Jiali Fan, Bingyuan Zhou, Caiming Zhao, Xin Zhao, Bo Su, Yuzhu Miao, Yuping Liao, Li Wang
{"title":"Myocardial strain measured via two-dimensional speckle-tracking echocardiography in a family diagnosed with arrhythmogenic left ventricular cardiomyopathy.","authors":"Changsheng Ma, Jiali Fan, Bingyuan Zhou, Caiming Zhao, Xin Zhao, Bo Su, Yuzhu Miao, Yuping Liao, Li Wang","doi":"10.1186/s12947-021-00270-1","DOIUrl":"https://doi.org/10.1186/s12947-021-00270-1","url":null,"abstract":"<p><strong>Background: </strong>Arrhythmogenic cardiomyopathy is a myocardial disorder characterized by ventricular arrhythmias, right and/or left ventricular involvement, and fibrofatty infiltrations in the myocardium. We report a family diagnosed with arrhythmogenic left ventricular cardiomyopathy (ALVC) and depict their echocardiographic characteristics.</p><p><strong>Methods and results: </strong>Fifteen family members were divided into three groups based on whether they carried the TMEM43 mutation and had been diagnosed with ALVC. Eight of them had TMEM43 mutations, and four were diagnosed with ALVC according to the Padua criteria. Only the proband experienced sudden cardiac death and had a dilated left ventricle. Left ventricular ejection fraction was reduced in two patients; however, left ventricular global longitudinal strain was depressed in three patients. Low QRS voltages in limb leads were evident in three patients, and five patients had frequent ventricular premature contractions. Late gadolinium enhancement was evident in three patients. Left ventricular layer-specific strain showed that the transmural strain gradient ratio was increased in patients diagnosed with ALVC, and it was elevated in the genotype-positive and phenotype-negative groups compared with healthy individuals.</p><p><strong>Conclusion: </strong>Global left ventricular longitudinal strain better evaluated left ventricular function than left ventricular ejection fraction. The transmural strain gradient ratio was elevated in patients diagnosed with ALVC, suggesting that it was useful for the evaluation of ALVC.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":"19 1","pages":"40"},"PeriodicalIF":1.9,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39742562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan Kline, Mary Golinski, Brian Selai, Jeremy Horsch, Katie Hornbaker
{"title":"The effectiveness of a blended POCUS curriculum on achieving basic focused bedside transthoracic echocardiography (TTE) proficiency. A formalized pilot study.","authors":"Jonathan Kline, Mary Golinski, Brian Selai, Jeremy Horsch, Katie Hornbaker","doi":"10.1186/s12947-021-00268-9","DOIUrl":"https://doi.org/10.1186/s12947-021-00268-9","url":null,"abstract":"<p><strong>Objective: </strong>The study objective is to evaluate the effeteness of an existing educational platform blending didactic presentation and hands-on simulation for university doctoral SRNAs in the area of basic, 4 view identification and performance of transthoracic echocardiography (TTE).</p><p><strong>Methods: </strong>Following IRB approval, SRNAs were exposed to a pre test to evaluate existing skills, then they were exposed to a graphic rich, live presentation of basic 4 view TTE. The presentation was then followed by hands on simulation and performance of the 4 basic TTE views on live models.</p><p><strong>Results: </strong>Pretest scores averaged 58% and post tests scores rose to 95%. See Table 1.</p><p><strong>Conclusion: </strong>Our results support the concept that the existing blended platform is effective to train university SRNAs in basic 4 view, bedside transthoracic echocardiography.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":"19 1","pages":"39"},"PeriodicalIF":1.9,"publicationDate":"2021-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39799409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ferit Onur Mutluer, Nikki van der Velde, Jason Voorneveld, Johan G Bosch, Jolien W Roos-Hesselink, Rob J van der Geest, Alexander Hirsch, Annemien van den Bosch
{"title":"Evaluation of intraventricular flow by multimodality imaging: a review and meta-analysis.","authors":"Ferit Onur Mutluer, Nikki van der Velde, Jason Voorneveld, Johan G Bosch, Jolien W Roos-Hesselink, Rob J van der Geest, Alexander Hirsch, Annemien van den Bosch","doi":"10.1186/s12947-021-00269-8","DOIUrl":"https://doi.org/10.1186/s12947-021-00269-8","url":null,"abstract":"<p><strong>Background: </strong>The aim of this systematic review was to evaluate current inter-modality agreement of noninvasive clinical intraventricular flow (IVF) assessment with 3 emerging imaging modalities: echocardiographic particle image velocimetry (EPIV), vector flow mapping (VFM), and 4-dimensional flow cardiovascular magnetic resonance imaging (4D flow CMR).</p><p><strong>Methods: </strong>We performed a systematic literature review in the databases EMBASE, Medline OVID and Cochrane Central for identification of studies evaluating left ventricular (LV) flow patterns using one of these flow visualization modalities. Of the 2224 initially retrieved records, 10 EPIV, 23 VFM, and 25 4D flow CMR studies were included in the final analysis.</p><p><strong>Results: </strong>Vortex parameters were more extensively studied with EPIV, while LV energetics and LV transport mechanics were mainly studied with 4D flow CMR, and LV energy loss and vortex circulation were implemented by VFM studies. Pooled normative values are provided for these parameters. The meta- analysis for the values of two vortex morphology parameters, vortex length and vortex depth, failed to reveal a significant change between heart failure patients and healthy controls.</p><p><strong>Conclusion: </strong>Agreement between the different modalities studying intraventricular flow is low and different methods of measurement and reporting were used among studies. A multimodality framework with a standardized set of flow parameters is necessary for implementation of noninvasive flow visualization in daily clinical practice. The full potential of noninvasive flow visualization in addition to diagnostics could also include guiding medical or interventional treatment.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":"19 1","pages":"38"},"PeriodicalIF":1.9,"publicationDate":"2021-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39813401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hoorak Poorzand, Mohammad Tayyebi, Sara Hosseini, Alireza Heidari Bakavoli, Faeze Keihanian, Lida Jarahi, Ali Hamadanchi
{"title":"Predictors of worsening TR severity after right ventricular lead placement: any added value by post-procedural fluoroscopy versus three -dimensional echocardiography?","authors":"Hoorak Poorzand, Mohammad Tayyebi, Sara Hosseini, Alireza Heidari Bakavoli, Faeze Keihanian, Lida Jarahi, Ali Hamadanchi","doi":"10.1186/s12947-021-00267-w","DOIUrl":"https://doi.org/10.1186/s12947-021-00267-w","url":null,"abstract":"<p><strong>Background: </strong>The effect of right ventricular (RV) leads on tricuspid valve has been already raised concerns, especially in terms of prognostic implication. For such assessment, three-dimensional transthoracic echocardiography (3D-TTE) has been used previously but there was no data on the use of post-procedural fluoroscopy in the literature.</p><p><strong>Methods: </strong>We prospectively enrolled 59 patients who underwent clinically indicated placement of pacemaker or implantable cardioverter defibrillator (ICD). Vena contracta (VC) and tricuspid regurgitation (TR) severity were measured using two-dimensional transthoracic echocardiography (2D-TTE) at baseline. Follow up 3D-TTE was performed 6 months after device implantation to assess TR severity and RV lead location.</p><p><strong>Results: </strong>Lead placement position in TV was defined in 51 cases.TR VC was increased after the lead placement, compared to the baseline study (VC: 3.86 ± 2.32 vs 3.18 ± 2.39; p = 0.005), with one grade worsening in TR in 25.4% of cases. The mean changes in VC levels were 1.14 ± 0.67 mm. Among all investigated parameters, VC changes were predicted based on lead placement position only in 3D-TTE (p < 0.001) while the other variables including fluoroscopy parameters were not informative.</p><p><strong>Conclusion: </strong>The RV Lead location examined by 3D-TTE seems to be a valuable parameter to predict the changes in the severity of the tricuspid regurgitation. Fluoroscopy findings did not improve the predictive performance, at least in short term follow up.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":"19 1","pages":"37"},"PeriodicalIF":1.9,"publicationDate":"2021-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39909879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}