Cardiovascular Ultrasound最新文献

{"title":"Blood speckle imaging compared with conventional Doppler ultrasound for transvalvular pressure drop estimation in an aortic flow phantom.","authors":"Cameron Dockerill,&nbsp;Harminder Gill,&nbsp;Joao Filipe Fernandes,&nbsp;Amanda Q X Nio,&nbsp;Ronak Rajani,&nbsp;Pablo Lamata","doi":"10.1186/s12947-022-00286-1","DOIUrl":"https://doi.org/10.1186/s12947-022-00286-1","url":null,"abstract":"<p><strong>Background: </strong>Transvalvular pressure drops are assessed using Doppler echocardiography for the diagnosis of heart valve disease. However, this method is highly user-dependent and may overestimate transvalvular pressure drops by up to 54%. This work aimed to assess transvalvular pressure drops using velocity fields derived from blood speckle imaging (BSI), as a potential alternative to Doppler.  METHODS: A silicone 3D-printed aortic valve model, segmented from a healthy CT scan, was placed within a silicone tube. A CardioFlow 5000MR flow pump was used to circulate blood mimicking fluid to create eight different stenotic conditions. Eight PendoTech pressure sensors were embedded along the tube wall to record ground-truth pressures (10 kHz). The simplified Bernoulli equation with measured probe angle correction was used to estimate pressure drop from maximum velocity values acquired across the valve using Doppler and BSI with a GE Vivid E95 ultrasound machine and 6S-D cardiac phased array transducer.</p><p><strong>Results: </strong>There were no significant differences between pressure drops estimated by Doppler, BSI and ground-truth at the lowest stenotic condition (10.4 ± 1.76, 10.3 ± 1.63 vs. 10.5 ± 1.00 mmHg, respectively; p > 0.05). Significant differences were observed between the pressure drops estimated by the three methods at the greatest stenotic condition (26.4 ± 1.52, 14.5 ± 2.14 vs. 20.9 ± 1.92 mmHg for Doppler, BSI and ground-truth, respectively; p < 0.05). Across all conditions, Doppler overestimated pressure drop (Bias = 3.92 mmHg), while BSI underestimated pressure drop (Bias = -3.31 mmHg).</p><p><strong>Conclusions: </strong>BSI accurately estimated pressure drops only up to 10.5 mmHg in controlled phantom conditions of low stenotic burden. Doppler overestimated pressure drops of 20.9 mmHg. Although BSI offers a number of theoretical advantages to conventional Doppler echocardiography, further refinements and clinical studies are required with BSI before it can be used to improve transvalvular pressure drop estimation in the clinical evaluation of aortic stenosis.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":"18"},"PeriodicalIF":1.9,"publicationDate":"2022-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40527221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tissue Doppler derived biphasic velocities during the pre and post-ejection phases: patterns, concordance and hemodynamic significance in health and disease.","authors":"Alaa Mabrouk Salem Omar,&nbsp;Diana Maria Ronderos Botero,&nbsp;Javier Arreaza Caraballo,&nbsp;Ga Hee Kim,&nbsp;Yeraz Khachatoorian,&nbsp;Jaclyn Kliewer,&nbsp;Mohamed Ahmed Abdel Rahman,&nbsp;Osama Rifaie,&nbsp;Jonathan N Bella,&nbsp;Edgar Argulian,&nbsp;Johanna Contreras","doi":"10.1186/s12947-022-00287-0","DOIUrl":"https://doi.org/10.1186/s12947-022-00287-0","url":null,"abstract":"<p><strong>Background: </strong>Pre-(PRE) and post-ejection (POE) velocities by mitral annular tissue Doppler (TD) are biphasic and may be related to myocardial deformations. We investigated the predominance and concordance of TD-PRE and POE velocities and their effect on myocardial functions in controls and in heart failure (HF) patients.</p><p><strong>Methods: </strong>Retrospectively, 84 HF patients [57.6 years, 28(33%) females, NYHA: 2.3 ± 0.6, EF: 55 ± 15%, 52(62%) preserved EF, and 32(38%) reduced EF], 42 normal young controls, and 26 asymptomatic age matched controls were included. Echocardiography was done and from mitral annular tissue Doppler recordings, the biphasic PRE and POE velocity signals were identified and compared between groups.</p><p><strong>Results: </strong>While controls had almost always predominantly positive PRE and negative POE, HF had more negative PRE and positive POE. Moreover, almost all controls exhibited normal concordance (positive PRE and negative POE). HF exhibited more abnormal concordance which was significantly associated with worse NYHA, and parameters of diastolic and systolic functions. Opposite PRE and POE velocities correlated significantly in all groups (PREp vs POEn: young:r = 0.52, p < 0.001, age controls:r = 0.79, p < 0.001, HFpEF: r = 0.56, p < 0.001, HFrEF: r = 0.42, p = 0.018; PREn vs POEp: young: r = 0.25,p = 0.1, age controls: r = 0.42, p = 0.04, HFpEF: r = 0.43, p = 0.004, HFrEF: r = 0.61, p < 0.001) and the ratios PRE-P/N and POE-N/P correlated significantly with E/e' in HF only.</p><p><strong>Conclusions: </strong>In physiological state, TD signals are predominantly positive during PRE and negative during POE. Opposite PRE and POE velocities corelate, representing the PRE-generation and POE-reversal of shortening-stretch relationships, the attenuation of which in HF may be related to elevated LV filling pressures. In HF, partially or completely reversed concordance of PRE and POE is associated with progressive worsening of clinical and hemodynamic profiles.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":"17"},"PeriodicalIF":1.9,"publicationDate":"2022-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40506124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can prenatal diagnosis of parachute mitral valve be achieved? A case report of fetal parachute mitral valve.","authors":"Xiaohui Dai,&nbsp;Jiao Chen,&nbsp;Hanmin Liu,&nbsp;Lin Wu,&nbsp;Fumin Zhao","doi":"10.1186/s12947-022-00288-z","DOIUrl":"https://doi.org/10.1186/s12947-022-00288-z","url":null,"abstract":"<p><p>Parachute mitral valve (PMV) is a common form of congenital mitral stenosis and is difficult to diagnose prenatally. This report describes a fetal case of PMV with coarctation of the aorta that was diagnosed at 25 weeks' gestation by echocardiography and confirmed at autopsy. We describe the ultrasonographic features in this case and present a useful sign for making a prenatal diagnosis of PMV.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":"16"},"PeriodicalIF":1.9,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40570569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal diagnosis of anomalous left brachiocephalic vein courses using high-definition flow render mode and spatiotemporal image correlation.","authors":"Tian-Gang Li,&nbsp;Bin Ma,&nbsp;Ping-An Qi","doi":"10.1186/s12947-022-00285-2","DOIUrl":"https://doi.org/10.1186/s12947-022-00285-2","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to examine the clinical value of high-definition (HD) flow render mode and spatiotemporal image correlation (STIC) to diagnose anomalous left brachiocephalic vein (LBCV) courses in fetuses.</p><p><strong>Methods and results: </strong>Seventeen cases of anomalous LBCV courses were diagnosed using two-dimensional (2D), HD-flow, and HD-flow combined with STIC images and retrospectively analyzed to examine the significance of using HD-flow combined with STIC technology in the diagnosis of anomalous LBCV courses.</p><p><strong>Conclusions: </strong>HD-flow combined with STIC technology can help in the diagnosis of anomalous fetal LBCV courses, and this technique has important clinical value.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":"15"},"PeriodicalIF":1.9,"publicationDate":"2022-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40407612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic characteristics of PRKAG2 syndrome: a research using three-dimensional speckle tracking echocardiography compared with sarcomeric hypertrophic cardiomyopathy","authors":"Lu Tang, Xuejie Li, Nianwei Zhou, Yingying Jiang, C. Pan, X. Shu","doi":"10.1186/s12947-022-00284-3","DOIUrl":"https://doi.org/10.1186/s12947-022-00284-3","url":null,"abstract":"","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42725722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left atrial morpho-functional remodeling in atrial fibrillation assessed by three dimensional speckle tracking echocardiography and its value in atrial fibrillation screening.","authors":"Lilian Bao, Lei Cheng, Xiufang Gao, Fangying Yan, Huihua Fan, Ying Shan, Yong Li, Haiming Shi, Guoqian Huang, Liwen Bao","doi":"10.1186/s12947-022-00282-5","DOIUrl":"10.1186/s12947-022-00282-5","url":null,"abstract":"<p><strong>Background: </strong>Three dimensional speckle tracking echocardiography (3D STE) is a novel technique combining 3D echocardiography and speckle tracking analysis. 3D STE software dedicated to the left atrium (LA) was recently available. Our study aimed to assess (1) atrial fibrillation (AF) related LA morpho-functional remodeling using 3D STE and (2) value of LA function parameters in identifying paroxysmal AF (PAF).</p><p><strong>Methods: </strong>One hundred thirty-nine PAF, 109 persistent AF (Per-AF) and 59 non-AF subjects underwent 3D STE. LA phasic volumes and total LA emptying fraction (LAEF) were obtained and used to calculate passive (pLAEF) and active LA emptying fraction (aLAEF) based on atrial contraction. LA longitudinal and circumferential strain representing reservoir (LASr/LASrc), conduit (LAScd/LAScdc) and pump (LASct/LASctc) function were also assessed.</p><p><strong>Results: </strong>3D STE was found to have good reproducibility. Increase of LA volumes and decrease of parameters representing LA reservoir and pump function were independently associated with AF as well as AF burden. The correlations between LA emptying fraction and LA circumferential strain representing the same function were always stronger than those with LA longitudinal strain (p < 0.001). Minimal LA volume, LAEF, aLAEF, LASrc and LASctc can be used to accurately differentiate PAF from non-AF subjects (AUC > 0.8) with great sensitivity and specificity.</p><p><strong>Conclusions: </strong>Assessing LA remodeling in AF using 3D STE was feasible. AF and AF burden were independently associated with LA enlargement and impairment of reservoir and pump function but not conduit function. LA function parameters can indicate underlying PAF and thus can guide AF screening strategy.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":"13"},"PeriodicalIF":1.9,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9061228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45523820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Left atrial contraction strain and controlled preload alterations, a study in healthy individuals","authors":"Peter Gottfridsson, R. A’roch, P. Lindqvist, Lucy Law, T. Myrberg, M. Hultin, Alexander A’Roch, M. Haney","doi":"10.1186/s12947-022-00281-6","DOIUrl":"https://doi.org/10.1186/s12947-022-00281-6","url":null,"abstract":"","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47236836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left ventricular high frame rate echo-particle image velocimetry: clinical application and comparison with conventional imaging","authors":"M. Strachinaru, J. Voorneveld, L. Keijzer, D. Bowen, F. Mutluer, F. J. Cate, N. de Jong, H. Vos, J. Bosch, A. E. Van den Bosch","doi":"10.1186/s12947-022-00283-4","DOIUrl":"https://doi.org/10.1186/s12947-022-00283-4","url":null,"abstract":"","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2022-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48505611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Difference in cardiac remodeling between female athletes and pregnant women: a case control study.","authors":"Loira Toncelli, Lucia Pasquini, Giulia Masini, Melissa Orlandi, Gabriele Paci, Federico Mecacci, Gianni Pedrizzetti, Giorgio Galanti","doi":"10.1186/s12947-022-00280-7","DOIUrl":"10.1186/s12947-022-00280-7","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to detect possible differences in reversible cardiac remodeling occurring in sport training and twin pregnancy.</p><p><strong>Background: </strong>cardiac remodeling occurs in athletes and pregnant women due to training and fetal requirements, respectively. These changes could be apparently similar.</p><p><strong>Methods: </strong>21 female elite athletes (23.2 ± 5.3 years), 25 women with twin pregnancies (35.4 ± 5.7 years) and 25 healthy competitive female athletes (controls), age-matched with pregnant women (34.9 ± 7.9 years), were enrolled. This latter group was included to minimize the effect of age on cardiac remodeling. All women evaluated through anamnestic collection, physical examination, 12 leads ECG, standard echocardiogram and strain analysis. Sphericity (SI) and apical conicity (ACI) indexes were also calculated.</p><p><strong>Results: </strong>Pregnant women showed higher LA dimension (p < 0.001) compared to both groups of athletes. LV e RV GLS were significantly different in pregnant women compared to female athletes (p = 0.02 and 0.03, respectively). RV GLS was also different between pregnant women and controls (p = 0.02). Pregnant women showed significantly higher S' wave compared to female athletes (p = 0.02) but not controls. Parameters of diastolic function were significantly higher in athletes (p = 0.08 for IVRT and p < 0.001 for E/A,). SI was lower in athletes in both diastole (p = 0.01) and systole (p < 0.001), while ACIs was lower in pregnant women (p = 0.04).</p><p><strong>Conclusions: </strong>Cardiac remodeling of athletes and pregnant women could be similar at first sight but different in LV shape and in GLS, highlighting a profound difference in longitudinal deformation between athletes and pregnant women. This difference seems not to be related with age. These findings suggest that an initial maternal cardiovascular maladaptation could occur in the third trimester of twin pregnancies.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":" ","pages":"10"},"PeriodicalIF":1.9,"publicationDate":"2022-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42853404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac microstructural alterations in immune-inflammatory myocardial disease: a retrospective case-control study.","authors":"Alan C Kwan,&nbsp;Gerran Salto,&nbsp;Trevor-Trung Nguyen,&nbsp;Elizabeth H Kim,&nbsp;Eric Luong,&nbsp;Pranoti Hiremath,&nbsp;David Ouyang,&nbsp;Joseph E Ebinger,&nbsp;Debiao Li,&nbsp;Daniel S Berman,&nbsp;Michelle M Kittleson,&nbsp;Jon A Kobashigawa,&nbsp;Jignesh K Patel,&nbsp;Susan Cheng","doi":"10.1186/s12947-022-00279-0","DOIUrl":"https://doi.org/10.1186/s12947-022-00279-0","url":null,"abstract":"<p><strong>Background: </strong>Immune-inflammatory myocardial disease contributes to multiple chronic cardiac processes, but access to non-invasive screening is limited. We have previously developed a method of echocardiographic texture analysis, called the high-spectrum signal intensity coefficient (HS-SIC) which assesses myocardial microstructure and previously associated with myocardial fibrosis. We aimed to determine whether this echocardiographic texture analysis of cardiac microstructure can identify inflammatory cardiac disease in the clinical setting.</p><p><strong>Methods: </strong>We conducted a retrospective case-control study of 318 patients with distinct clinical myocardial pathologies and 20 healthy controls. Populations included myocarditis, atypical chest pain/palpitations, STEMI, severe aortic stenosis, acute COVID infection, amyloidosis, and cardiac transplantation with acute rejection, without current rejection but with prior rejection, and with no history of rejection. We assessed the HS-SIC's ability to differentiate between a broader diversity of clinical groups and healthy controls. We used Kruskal-Wallis tests to compare HS-SIC values measured in each of the clinical populations with those in the healthy control group and compared HS-SIC values between the subgroups of cardiac transplantation rejection status.</p><p><strong>Results: </strong>For the total sample of N = 338, the mean age was 49.6 ± 20.9 years and 50% were women. The mean ± standard error of the mean of HS-SIC were: 0.668 ± 0.074 for controls, 0.552 ± 0.049 for atypical chest pain/palpitations, 0.425 ± 0.058 for myocarditis, 0.881 ± 0.129 for STEMI, 1.116 ± 0.196 for severe aortic stenosis, 0.904 ± 0.116 for acute COVID, and 0.698 ± 0.103 for amyloidosis. Among cardiac transplant recipients, HS-SIC values were 0.478 ± 0.999 for active rejection, 0.594 ± 0.091 for prior rejection, and 1.191 ± 0.442 for never rejection. We observed significant differences in HS-SIC between controls and myocarditis (P = 0.0014), active rejection (P = 0.0076), and atypical chest pain or palpitations (P = 0.0014); as well as between transplant patients with active rejection and those without current or prior rejection (P = 0.031).</p><p><strong>Conclusions: </strong>An echocardiographic method can be used to characterize tissue signatures of microstructural changes across a spectrum of cardiac disease including immune-inflammatory conditions.</p>","PeriodicalId":9613,"journal":{"name":"Cardiovascular Ultrasound","volume":"20 1","pages":"9"},"PeriodicalIF":1.9,"publicationDate":"2022-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10450727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}