Ibrahima Sory Cherif, Esme Marie Laure Essis, Mamadou Alpha Diallo, Loukou Léandre Konan, Aly Antoine Kamano, Djoukou Olga Denise Kpebo, Seydou Dia, Mamadou Oury Baldé, Sory Condé, Fatoumata Cherif, Momory Millimono, Fanta Mady Kouyaté, Angelo Loua, Lila Condé
{"title":"Missed Opportunities for Timely Diagnosis and Effective Therapeutic Management of Prolonged Fever: A Case Study of Confirmed Lassa Fever in N'Zérékoré, Guinea, 2022.","authors":"Ibrahima Sory Cherif, Esme Marie Laure Essis, Mamadou Alpha Diallo, Loukou Léandre Konan, Aly Antoine Kamano, Djoukou Olga Denise Kpebo, Seydou Dia, Mamadou Oury Baldé, Sory Condé, Fatoumata Cherif, Momory Millimono, Fanta Mady Kouyaté, Angelo Loua, Lila Condé","doi":"10.1155/crdi/2672939","DOIUrl":"10.1155/crdi/2672939","url":null,"abstract":"<p><strong>Background: </strong>Lassa fever is a potentially fatal viral hemorrhagic disease caused by a ribonucleic acid (RNA) virus of the <i>Arenaviridae</i> family, endemic in West Africa. It is highly virulent and contagious in several countries, with a nonspecific clinical presentation that poses a major public health challenge. An in-depth investigative survey was conducted in N'Zérékoré to identify the transmission chain of a confirmed case of Lassa fever.</p><p><strong>Case presentation: </strong>This study reports a confirmed case of Lassa fever diagnosed 13 days after the onset of persistent fever. The disease was suspected at the regional hospital of N'Zérékoré following the worsening of the initial clinical picture, characterized by the onset of hemorrhagic manifestations and failure of antibiotic therapy. Confirmation of Lassa virus infection by reverse transcriptase-polymerase chain reaction (RT-PCR) on a blood sample was obtained a day prior to the patient's death. The patient did not receive ribavirin treatment and remained on the same antibiotic regimen (ceftriaxone) from the onset of fever, combined with dexamethasone, omeprazole, and a unit of blood transfusion.</p><p><strong>Conclusion: </strong>The therapeutic pathway of this confirmed Lassa fever case in N'Zérékoré highlights the need for improved management of viral hemorrhagic fevers and consideration of differential diagnoses when broad-spectrum antibiotic therapy fails.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"2672939"},"PeriodicalIF":0.8,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13291718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148327011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Concurrent <i>Nocardia</i>, <i>Cryptococcus</i> and <i>Mycobacterium</i> Infections Unmask Anti-GM-CSF Antibody-Associated Immunodeficiency and Pulmonary Alveolar Proteinosis: A Case Report.","authors":"Vidthiya Menon","doi":"10.1155/crdi/5939262","DOIUrl":"10.1155/crdi/5939262","url":null,"abstract":"<p><p>Anti-granulocyte macrophage colony stimulating factor (anti-GM-CSF) antibodies, classically associated with pulmonary alveolar proteinosis (PAP), are increasingly recognised as a cause of adult-onset immunodeficiency predisposing to opportunistic infections. Coinfections with multiple opportunistic pathogens in this context are uncommon. We describe a rare case of disseminated <i>Nocardia paucivorans</i>, pulmonary <i>Cryptococcus gattii,</i> pulmonary <i>Mycobacterium chelonae</i>, and subsequent PAP in a patient with high-level anti-GM-CSF antibodies. A 64-year-old man presented with subacute bilateral shoulder pain and was diagnosed with acromioclavicular septic arthritis. <i>N. paucivorans</i> was isolated, and subsequent evaluation demonstrated disseminated infection with numerous brain abscesses, left eye endophthalmitis and pulmonary involvement. Interval computed tomography of the chest revealed new right lower lobe consolidation, a biopsy of which identified <i>C. gattii</i> and <i>M. chelonae</i>. Immunological testing confirmed high-level anti-GM-CSF antibodies. The patient received prolonged combination antimicrobial therapy, including meropenem, ceftriaxone, linezolid, trimethoprim-sulfamethoxazole, moxifloxacin, fluconazole, tigecycline and clofazimine, with clinical and radiological improvement of infectious lesions. Despite microbiological clearance, progressive bilateral ground-glass opacities developed on serial chest imaging consistent with PAP, with no pathogens identified on bronchoscopic sampling. Given minimal respiratory symptoms, PAP-directed therapy was deferred. The patient remains clinically stable on trimethoprim-sulfamethoxazole prophylaxis with ongoing clinical and radiological surveillance. This case illustrates the expanding clinical spectrum of anti-GM-CSF antibody-associated disease and underscores the importance of considering this diagnosis in patients presenting with opportunistic infections, in particular, disseminated nocardiosis or <i>C</i>. <i>gattii</i> infection. It also highlights the need for vigilance in evaluating for coinfections, recognition of PAP as a noninfectious codiagnosis, and the importance of long-term follow-up in affected patients.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"5939262"},"PeriodicalIF":0.8,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13291555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148327024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"HIV-1 Resistance to Dolutegravir in Benin: The Need to Improve and Strengthen Therapeutic Patient Education Strategies to Achieve the Third Objective 95 of UNAIDS 95-95-95 Target.","authors":"Edmond Tchiakpe, Halimatou Diop-Ndiaye, Sophia Osawe, Coumba Toure-Kane, Akadiri Yessoufou","doi":"10.1155/crdi/9324746","DOIUrl":"10.1155/crdi/9324746","url":null,"abstract":"<p><p>Benin has adopted the WHO 2019 recommendations by integrating dolutegravir into the first- and second-line treatment regimen with regular monitoring of the emergence of resistance. The standard of care document has been updated, and healthcare staff have been trained on dosage, drug interactions, and the management of adverse effects. The patient, diagnosed as HIV-1 positive, was started on antiretroviral therapy, which had to be modified due to poor adherence. HIV-RNA was extracted from plasma with QIAGEN RNA kit, and nested polymerase chain reaction was performed in Reference National Laboratory of Health Program Fighting Against AIDS in Benin on the polymerase gene using the Applied Biosystems HIV-1 Genotyping Kit PR-RT with Integrase. Drug resistance mutations and the remaining effective antiretrovirals drug were identified using Stanford University Antiretroviral-Associated Resistance Mutation Interpretation Algorithm (https://hivdb.stanford.edu/ Version 9.8). The phylogenetic tree was constructed using SeaView with the maximum likelihood method and 1000 bootstrap iterations to identify the viral subtype along PR-RT and integrase gene. No PI-associated resistance mutations were observed. The NRTIs and NNRTIs associated resistance mutations were (M41 ML, D67G, S68G, K70R, M184 V, T215F, and K219E), (V179E and Y188 L), respectively. The major and accessory INSTI mutations observed were (E138 K, G140 GA, S147SG, Q148R, and N155H) and T97A, respectively. All protease inhibitors were effective against the identified HIV-1 viral strain which was a CRF02_AG along the polymerase gene. HIV-1 resistance genotyping can improve monitoring of the emergence of resistance in nonadherent individuals and anticipate early treatment failures in order to accelerate access to the third 95 of UNAIDS 95-95-95 target.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"9324746"},"PeriodicalIF":0.8,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13284734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148307036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elena Gloria Torres García, Cristina Marcelo Calvo, Paula Navarro-Carrera, Alejandro Díez-Vidal, Beatriz Díaz-Pollán
{"title":"<i>Candida glabrata</i> Prostatitis: A Rare Case in a Patient With Type 2 Diabetes Mellitus on Dapagliflozin Treatment.","authors":"Elena Gloria Torres García, Cristina Marcelo Calvo, Paula Navarro-Carrera, Alejandro Díez-Vidal, Beatriz Díaz-Pollán","doi":"10.1155/crdi/7705938","DOIUrl":"10.1155/crdi/7705938","url":null,"abstract":"<p><p>We present a case of acute <i>Candida glabrata</i> prostatitis complicated by secondary candidemia in a 72-year-old man with poorly controlled Type 2 diabetes mellitus and benign prostatic hyperplasia, without classical healthcare-associated risk factors for invasive candidiasis. The patient presented with fever, urinary symptoms, and markedly elevated prostate-specific antigen. Urine and blood cultures confirmed disseminated <i>C. glabrata</i> infection. Despite a comprehensive diagnostic workup, no alternative source of candidemia was identified, supporting primary prostatic infection with secondary hematogenous dissemination. Among the identified predisposing factors was ongoing treatment with dapagliflozin, a sodium-glucose cotransporter 2 inhibitor (SGLT2 inhibitor). While SGLT2 inhibitor use is established as a risk factor for superficial mycotic genitourinary infections, invasive fungal complications remain poorly characterized. This case suggests that the SGLT2 inhibitor-induced glucosuria, in combination with structural urinary obstruction and poorly controlled diabetes, may contribute to invasive fungal infections and highlights the need for clinical vigilance in patients with multiple converging risk factors.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"7705938"},"PeriodicalIF":0.8,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13284547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148307076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pulmonary Paragonimiasis Presenting as Pneumothorax, Hemoptysis, and Severe Eosinophilia: A Case Report.","authors":"Ashok Basnet, Mukti Nath Sankhi, Chiranjibi Pant, Rohit Vashisht, Alina Singh, Brikshya Gurung, Bishal Kunwor","doi":"10.1155/crdi/1991391","DOIUrl":"10.1155/crdi/1991391","url":null,"abstract":"<p><p>Paragonimiasis is a foodborne zoonosis transmitted mostly by the consumption of inadequately cooked crabs and crayfish harboring <i>Paragonimus</i> metacercariae. We present the case of a 38-year-old male with a history of crab ingestion who developed severe eosinophilia, transaminitis, and serositis. Initial presentation included fever, epigastric pain, weight loss, and pleural effusion. He was managed empirically with albendazole and corticosteroids along with other supportive measures. Two months later, he re-presented with hemoptysis and hypoxemia. HRCT showed multiple cavitary pulmonary lesions, pleural nodules, and left-sided pneumothorax. Sputum wet mount demonstrated <i>Paragonimus</i> species ova, confirming pulmonary paragonimiasis. The patient was managed with intercostal tube drainage, tranexamic acid nebulization, and praziquantel with clinical improvement. This case highlights the importance of considering paragonimiasis in patients, even with pneumothorax, when the patient has hemoptysis and eosinophilia in the background of ingestion of raw or undercooked crustaceans in endemic regions.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"1991391"},"PeriodicalIF":0.8,"publicationDate":"2026-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13284485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148307054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bernacchia D, Rigoni M, Canavesi G, Franzetti M, Pagani G, Bassani F, Verrengia E, Gottardo R, Di Toma L F, Pavia C, Rusconi S
{"title":"Acute Encephalopathy in Multiple Sclerosis With Renal Failure: Synergistic Neurotoxicity of Baclofen and Meropenem.","authors":"Bernacchia D, Rigoni M, Canavesi G, Franzetti M, Pagani G, Bassani F, Verrengia E, Gottardo R, Di Toma L F, Pavia C, Rusconi S","doi":"10.1155/crdi/7420497","DOIUrl":"10.1155/crdi/7420497","url":null,"abstract":"<p><p>The clinical case of a 62-year-old male with a history of secondary progressive multiple sclerosis (MS), who developed acute encephalopathy during antibiotic therapy with meropenem for a urinary tract infection (UTI) by Proteus mirabilis ESBL-producing is reported here. The clinical course revealed an altered level of consciousness, seizures, and electroencephalographic abnormalities, which were initially attributed to antibiotic toxicity. However, further investigation revealed an overdose of baclofen, a muscle relaxant the patient had been taking for several years, leading to the diagnosis of acute metabolic encephalopathy. Moreover, given the patient's impaired renal function, a possible interaction between baclofen and meropenem neurotoxicity was suspected, likely related to their combined effects on GABA receptors. While baclofen and meropenem neurotoxicity are well-documented individually, their potential interaction remains poorly understood, particularly in patients with altered renal function. This case highlights the importance of considering drug toxicity and interactions in patients with altered mental status, especially in those with polypharmacy and comorbid conditions.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"7420497"},"PeriodicalIF":0.8,"publicationDate":"2026-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13282454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148293544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicolas Riveros-Neira, Benjamin J Behers, Palwusha Khan, Patricia Riano-Rivero, Kathryn Lago, Karen M Hamad
{"title":"Lumbosacral Discitis and Vertebral Osteomyelitis Caused by ESBL-Producing <i>Escherichia coli</i> in an Immunocompetent Patient.","authors":"Nicolas Riveros-Neira, Benjamin J Behers, Palwusha Khan, Patricia Riano-Rivero, Kathryn Lago, Karen M Hamad","doi":"10.1155/crdi/9438574","DOIUrl":"10.1155/crdi/9438574","url":null,"abstract":"<p><p>Discitis and vertebral osteomyelitis are rare spinal infections that are difficult to diagnose due to nonspecific presentations. This case report describes a 62-year-old immunocompetent female presenting with recurrent lower back pain and imaging findings concerning for lumbosacral discitis. Initial cultures and biopsy were inconclusive, but surgical intervention confirmed vertebral osteomyelitis caused by an extended-spectrum beta-lactamase (ESBL)-producing <i>Escherichia coli</i>. The patient responded well to targeted carbapenem therapy and was placed on chronic suppressive treatment with minocycline. Our case highlights the diagnostic challenges of lumbosacral discitis and the importance of considering multidrug-resistant, gram-negative pathogens even in low-risk patients.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"9438574"},"PeriodicalIF":0.8,"publicationDate":"2026-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13282453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148293547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luiz Felipe Azevedo Marques, Adriele Evelyn Ferreira Silva, Patrícia Teixeira Costa, Lucas Silva Mello, Vinícius Santiago Dos Santos, Fernando Augusto Lima Marson
{"title":"Patients With Berardinelli-Seip and Silver-Russell Syndromes Hospitalized due to Coronavirus Disease (COVID)-19 in Brazil: A Four-Year Case Report Profile.","authors":"Luiz Felipe Azevedo Marques, Adriele Evelyn Ferreira Silva, Patrícia Teixeira Costa, Lucas Silva Mello, Vinícius Santiago Dos Santos, Fernando Augusto Lima Marson","doi":"10.1155/crdi/5881408","DOIUrl":"10.1155/crdi/5881408","url":null,"abstract":"<p><p>Berardinelli-Seip syndrome is a rare genetic disorder characterized by the near absence of subcutaneous fat and a high prevalence of metabolic complications, such as diabetes mellitus and cardiovascular disease, which may worsen coronavirus disease (COVID)-19 outcomes. Silver-Russell syndrome, also a rare genetic condition, involves intrauterine growth restriction and multiple metabolic and physical abnormalities that could potentially worsen prognosis after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This study analyzed five hospitalized patients in Brazil, two with Berardinelli-Seip syndrome and three with Silver-Russell syndrome, with confirmed COVID-19. The results showed that most patients presented respiratory symptoms and peripheral oxygen saturation below 95% at admission. Among the cases, two required intensive care and two required noninvasive ventilatory support. Four patients were discharged, while one 19-year-old patient with Berardinelli-Seip syndrome, who had multiple comorbidities and was unvaccinated, died. Symptom onset preceded hospitalization by 2-8 days in Berardinelli-Seip and 2-7 days in Silver-Russell patients. Time from symptom onset to outcome ranged from 6 to 10 days. Hospital stays were short (2-6 days). No Berardinelli-Seip patient required intensive care unit admission; two Silver-Russell patients required brief intensive care unit stays. Overall progression remained under 2 weeks. The study did not identify a consistent association between COVID-19 severity and the presence of these two syndromes, although regular multidisciplinary follow-up may have contributed to favorable outcomes in patients with Silver-Russell syndrome. Despite diagnostic and data-source limitations, the findings suggest that these rare conditions were not uniformly associated with poor outcomes, contrary to initial expectations. Further studies with larger cohorts are needed to clarify the interaction between rare diseases and COVID-19, improve risk stratification, and support clinical management in future public health emergencies.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"5881408"},"PeriodicalIF":0.8,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13273523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148276057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily Ehsan, Ellie Staab, Katie Geelan-Hansen, Richard Hankins
{"title":"Relapsing Nasal Septal Leishmaniasis: Lessons in Long-Term Multidisciplinary Management Case Report.","authors":"Emily Ehsan, Ellie Staab, Katie Geelan-Hansen, Richard Hankins","doi":"10.1155/crdi/1784961","DOIUrl":"10.1155/crdi/1784961","url":null,"abstract":"<p><strong>Introduction: </strong>Mucosal leishmaniasis (ML) is a rare, destructive, and recurrent protozoal infection caused by <i>Leishmania</i> species, most commonly <i>Leishmania braziliensis</i>. ML can develop months to years after initial cutaneous leishmaniasis (CL) and may lead to severe mucosal destruction if untreated.</p><p><strong>Case presentation: </strong>We present a case of a 48-year-old healthy male from Venezuela with prior CL treated with intravenous meglumine antimoniate who subsequently developed progressive nasal symptoms consistent with ML. Initial therapy with oral fluconazole was ineffective, but treatment with miltefosine led to symptom resolution. The patient underwent four-staged reconstructive surgeries with ENT. Thirty-eight months later, the patient developed recurrent symptoms, and biopsy confirmed infection with <i>L. braziliensis</i>. He was subsequently treated with intravenous amphotericin B, which led to clinical improvement.</p><p><strong>Discussion: </strong>This case highlights the relapsing nature of ML, its potential for extensive mucosal damage, and the importance of a structured, long-term care plan. This case in particular is unique given the extended delay before recurrence following miltefosine therapy. The high recurrence rate of <i>L. braziliensis</i> infections underscores the importance of vigilant long-term follow-up and consideration of systemic therapy. Multidisciplinary management is often necessary to optimize outcomes.</p><p><strong>Conclusion: </strong>Early recognition of ML, timely systemic therapy, structured multidisciplinary care, and adherence to a long-term surveillance plan are critical to prevent mucosal destruction and manage relapses effectively. Extended surveillance may be warranted to detect late relapses in patients treated with newer or more effective agents.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"1784961"},"PeriodicalIF":0.8,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13273630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148276137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siwar Belhaj Salem, Ariba Furqan, Ramla Mohamed Farah Roble, Sarah Suwal, Linh Huynh, Syed Muhammad Hassan, Sara S
{"title":"Community-Acquired Pneumonia Manifested by Acute Abdominal Pain: A Case Report.","authors":"Siwar Belhaj Salem, Ariba Furqan, Ramla Mohamed Farah Roble, Sarah Suwal, Linh Huynh, Syed Muhammad Hassan, Sara S","doi":"10.1155/crdi/3797000","DOIUrl":"10.1155/crdi/3797000","url":null,"abstract":"<p><p>Pneumonia is a common acute respiratory infection that affects the alveoli and distal airways and typically presents with symptoms such as chest pain, cough, dyspnea, and fever. However, it can also manifest with nonspecific symptoms like abdominal pain. This case report presents a previously healthy 24-year-old male who initially presented with severe right upper quadrant abdominal pain and fever. Despite initial treatment, the patient's condition worsened, with the emergence of dyspnea and productive cough. Subsequent examination and imaging revealed community-acquired pneumonia (CAP) caused by <i>Streptococcus pneumoniae</i>. The diagnosis was confirmed through clinical examination, chest X-ray showing a right lower lobe infiltrate, and sputum analysis. The patient was successfully treated with intravenous fluoroquinolone and oral antibiotics upon discharge. This case underscores the importance of considering CAP in the differential diagnosis of acute abdominal pain to avoid misdiagnosis and ensure timely treatment. It highlights the need for awareness of atypical presentations of CAP.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"3797000"},"PeriodicalIF":0.8,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13273026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148276096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}