Ramya Varadarajan, Ashmi P Patel, Keyvon Rashidi, Albert Oh, Rashmeen Rahman, Ryan Neal
{"title":"Flea-Borne Typhus Presenting with Acalculous Cholecystitis and Severe Anemia.","authors":"Ramya Varadarajan, Ashmi P Patel, Keyvon Rashidi, Albert Oh, Rashmeen Rahman, Ryan Neal","doi":"10.1155/2023/5510295","DOIUrl":"10.1155/2023/5510295","url":null,"abstract":"<p><strong>Background: </strong>Flea-borne typhus (FBT), an uncommon illness in the United States, typically presents as a high continuous fever with commonly associated symptoms including headache, myalgias, and rashes on the trunk and extremities. Patients infected with FBT may also present with atypical symptoms. As such, the combination of its relatively low incidence in the United States coupled with its variability in associated symptoms poses a diagnostic challenge for clinicians; early empiric treatment with doxycycline is warranted prior to a definitive diagnosis to reduce the risk of damage to vital organs. <i>Case Report</i>. This case describes a 54-year-old male who presented to an emergency room in Houston, Texas, with one week of constant right upper quadrant abdominal pain and fevers up to 40°C. The patient was initially diagnosed with Grade III severe acute cholangitis after abdominal ultrasound revealed gallbladder sludge and wall thickening without ductal dilatation, but a subsequent endoscopic retrograde cholangiopancreatography was unremarkable. Following intermittent fevers and worsening anemia, the patient was started on oral doxycycline for atypical infection, and an infectious disease workup subsequently returned a positive titer for <i>Rickettsia typhi</i>. He experienced rapid symptomatic and clinical improvement, and the patient was discharged home with a final diagnosis of flea-borne typhus.</p><p><strong>Conclusion: </strong>Albeit uncommon, the presentation of this patient's symptoms and final diagnosis of flea-borne typhus demonstrates the importance of (1) keeping atypical infections such as FBT in the differential diagnosis and (2) beginning empiric treatment to prevent damage to vital organs if suspicion of FBT is high.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"5510295"},"PeriodicalIF":1.1,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89716981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enterovirus-Rhinovirus-Induced Acute Respiratory Distress Syndrome in Adults: A Case Report and Short Literature Review.","authors":"Eirini Avgoustou, Aikaterini Spyridaki, Giorgos Pothitos, Antonios Papadopoulos, Spyridon Kois, Foula Vassilara","doi":"10.1155/2023/8887955","DOIUrl":"10.1155/2023/8887955","url":null,"abstract":"<p><p>Enteroviruses and rhinoviruses (EV-RV) are small RNA viruses that usually cause the common cold and asthma exacerbations. Although EV-RV-induced acute respiratory distress syndrome (ARDS) is common in children, only scattered reports of ARDS in adults have been published. The diagnosis has been greatly facilitated by the advent of molecular techniques, namely, real-time polymerase chain reaction (RT-PCR). EV-RV can cause ARDS by stimulating a cytokine cascade. No antiviral therapy has yet been approved, and treatment is entirely supportive. Herein, we report a rare case of EV-RV infection in an afebrile adult with dyspnea that rapidly progressed to acute lung injury and ARDS. EV-RV was isolated with multiple real-time PCR in nasopharyngeal and bronchial specimens, while no other pathogen was detected. We also present an up-to-date review of relevant literature, in an attempt to stress the importance of the early identification of viral culprits, which can minimize the use of invasive diagnostic procedures and antibiotic agents.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"8887955"},"PeriodicalIF":1.1,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89716980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"<i>Pneumocystis jirovecii</i> Pneumonia in a HIV-Infected Patient with a CD4 Count Greater Than 400 Cells/<i>μ</i>L and Atovaquone Prophylaxis\".","authors":"Gilles Nevez, Claire Hoffmann, Solène Le Gal","doi":"10.1155/2023/9793264","DOIUrl":"https://doi.org/10.1155/2023/9793264","url":null,"abstract":"<jats:p />","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"9793264"},"PeriodicalIF":1.1,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615577/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71421011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Persistent Vulvar Itch Unresponsive to Treatment: A Case of Vulvar Schistosomiasis Caused by <i>Schistosoma mansoni</i> and a Brief Review of Literature.","authors":"Anthony Gyening-Yeboah, Solomon E Quayson","doi":"10.1155/2023/9913905","DOIUrl":"10.1155/2023/9913905","url":null,"abstract":"<p><strong>Background: </strong>Vulvar schistosomiasis is a female genital schistosomiasis (FGS), which occurs because of the damage caused by the presence of schistosome ova within the vulva. FGS is mostly misdiagnosed as a sexually transmitted infection. There is no reported case of vulvar schistosomiasis from <i>Schistosoma mansoni</i> in an immunocompetent or immunocompromised person in Ghanaian medical literature; however, there is a reported case of <i>S. haematobium</i> in an immunocompromised person. This is the first case of vulvar schistosomiasis from <i>S. mansoni</i> infection in an immunocompromised person. This case report discusses the need to consider vulvar schistosomiasis in patients with itchiness of the vulva. <i>Case Presentation</i>. A sixty-nine-year-old married woman presents with a persistent vulvar itch that is unresponsive to treatment. A clinical diagnosis of vulvar lichen planus unresponsive to medical therapy was made. A histopathological diagnosis of vulvar schistosomiasis was, however, made. Ziehl-Neelsen stain revealed the ova of <i>Schistosoma mansoni</i>. Symptoms resolved on administration of oral praziquantel.</p><p><strong>Conclusion: </strong>Vulvar schistosomiasis must be considered in clinical history-taking and investigation of signs and symptoms related to itchiness of the vulva. Ziehl-Neelsen staining is a helpful histopathology armamentarium to determine the species of schistosome ova.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"9913905"},"PeriodicalIF":1.1,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54227787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ferdinand Bigirimana, Sigi Van den Wijngaert, Christelle Fosso, Karolien Stoffels, Charlotte Martin, Evelyne Maillart, Philippe Clevenbergh
{"title":"Lenacapavir with Fostemsavir in a Multidrug-Resistant HIV-Infected Hemodialysis Patient.","authors":"Ferdinand Bigirimana, Sigi Van den Wijngaert, Christelle Fosso, Karolien Stoffels, Charlotte Martin, Evelyne Maillart, Philippe Clevenbergh","doi":"10.1155/2023/8865265","DOIUrl":"10.1155/2023/8865265","url":null,"abstract":"<p><p>We report a hemodialysis MDR HIV-infected patient switched to fostemsavir with lenacapavir plus lamivudine for more than a year. She maintained a suppressed viral replication and did not present any clinical or biological drug-related side effects. The combination of lenacapavir plus fostemsavir looks promising in terms of safety and efficacy even in patients with end-stage renal disease awaiting renal transplant. Both drugs are first in class ARVs so that there is no cross resistance with previous drugs, maintaining their efficacy against MDR HIV.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"8865265"},"PeriodicalIF":1.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54227786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmad Ahsen, Philip Korsun, Fadi Albahra, Ranjit Nair, Zain Tariq
{"title":"<i>Capnocytophaga canimorsus</i> Infection in a 38-Year-Old Male after a Dog Bite.","authors":"Ahmad Ahsen, Philip Korsun, Fadi Albahra, Ranjit Nair, Zain Tariq","doi":"10.1155/2023/9917898","DOIUrl":"10.1155/2023/9917898","url":null,"abstract":"<p><p>Here, we present a unique case of a 38-year-old male with a history of alcohol use disorder and multiple sexual partners, who presented with fulminant sepsis with shock, multiorgan failure, and livedo racemosa after a dog bite the week prior. The patient was intubated on arrival and was started on vasopressors and antibiotics. Eventually, the patient's clinical status improved, and he was transferred out of the intensive care unit. Blood cultures tested positive for oxidase-positive Gram-negative rods two days after collection, and species identification showed <i>Capnocytophaga canimorsus</i>.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"9917898"},"PeriodicalIF":1.1,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50157130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ning Xu, Lei Zhu, Liyan Xiong, Jingjing Huo, Bin Wang, Xianyan Wu, Rui Tao, Qi Sa
{"title":"A Case of Central Venous Catheter-Related Bacteremia Caused by Enterococcus gallinarum","authors":"Ning Xu, Lei Zhu, Liyan Xiong, Jingjing Huo, Bin Wang, Xianyan Wu, Rui Tao, Qi Sa","doi":"10.1155/2023/9063371","DOIUrl":"https://doi.org/10.1155/2023/9063371","url":null,"abstract":"A chicken farmer with cirrhosis and renal failure presented with an unusual case of catheter-related bacteremia. Testing with the VITEK® 2 Compact system, MALDI-TOF mass spectrometry, and 16S rDNA sequencing identified the pathogen as E. gallinarum. This case demonstrates the importance of maintaining a high level of contextual awareness in patients exposed to avian species to make an informed diagnosis and provide prompt treatment.","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135968600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Celeste Ruiz Holgado, Joanna Iris Depasupil, Michael Stracher, Esra Fakioglu, Lily Q Lew
{"title":"<i>Staphylococcus schleiferi</i>: An Uncommon Pathogen in an Immunocompetent Adolescent with Chronic Osteomyelitis.","authors":"Maria Celeste Ruiz Holgado, Joanna Iris Depasupil, Michael Stracher, Esra Fakioglu, Lily Q Lew","doi":"10.1155/2023/9597582","DOIUrl":"10.1155/2023/9597582","url":null,"abstract":"<p><p><i>Staphylococcus schleiferi</i> represents an uncommon pathogen in human infections. As a veterinary pathogen, <i>S. schleiferi</i> causes canine ear and skin infections. Chronic osteomyelitis is a progressive process characterized by bone destruction and the formation of sequestrum. It may be a sequela of untreated or undertreated acute osteomyelitis or septic arthritis. Descriptions detailing the pathogenicity and virulence of <i>S. schleiferi</i> osteomyelitis were limited to a few case reports. Among the three reported cases of <i>S. schleiferi</i> osteomyelitis, immunosuppression, malignancy, and recent surgical procedures were comorbidities. Compared to those who are immunosuppressed, immunocompetent individuals are generally not susceptible to uncommon microorganisms. Early detection of osteomyelitis, aggressive appropriate prolonged antimicrobial treatment and a multidisciplinary approach contribute to optimal recovery. We report the first case of <i>S. schleiferi</i> chronic osteomyelitis in an immunocompetent adolescent.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"9597582"},"PeriodicalIF":1.1,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49688854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Carbapenem-Resistant <i>Acinetobacter baumannii</i> Bloodstream Infection in a Ghanaian Patient with Unilateral Diaphragmatic Eventration and HIV Type 1 Infection.","authors":"Yvonne Ayerki Nartey, Augustine Boakye Donkor, Ampem Darko Jnr Siaw, Oluwayemisi Esther Ekor, Bashiru Babatunde Jimah","doi":"10.1155/2023/9930291","DOIUrl":"10.1155/2023/9930291","url":null,"abstract":"<p><p>Carbapenem-resistant <i>Acinetobacter baumannii</i> infection is a critically prioritized pathogen by the World Health Organization and a cause for growing concern due to increased mortality among hospitalised patients. Phrenic nerve palsy is a rare complication of herpes zoster infection of the C3, C4, and C5 nerve roots. We present a case of bloodstream carbapenem-resistant <i>A. baumannii</i> infection in a Ghanaian patient with HIV type 1 infection and multiple risk factors, including unilateral diaphragmatic eventration with compression atelectasis likely secondary to phrenic nerve palsy due to herpes zoster infection, consequently leading to recurrent hospital and ICU admission. In this case, we emphasize the need for clinicians in LMICs to be aware of CRAB, in order to advocate for the availability of evidence-based medicines in resource-limited settings for appropriate treatment. In addition, we illustrate the importance of a high index of suspicion for infection with carbapenem-resistant organisms such as <i>A. baumannii</i> and highlight a rare and severe complication of herpes zoster infection in the form of phrenic nerve palsy and consequent diaphragmatic eventration.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"9930291"},"PeriodicalIF":1.1,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49688855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabel Cristina Hurtado, Raul Vallejo-Serna, Juan Sebastian Hurtado-Zapata, Sandra Patricia Misnaza
{"title":"Guillain-Barré Syndrome Post COVID-19 Vaccination with ChAdOx1 nCoV-19 Vaccine: A Colombian Case Report.","authors":"Isabel Cristina Hurtado, Raul Vallejo-Serna, Juan Sebastian Hurtado-Zapata, Sandra Patricia Misnaza","doi":"10.1155/2023/3290956","DOIUrl":"10.1155/2023/3290956","url":null,"abstract":"<p><strong>Background: </strong>Adverse events after vaccination against COVID-19 include rare events, such as Guillain-Barré syndrome. <i>Study Aims</i>. Documentation of clinical and temporary characteristics of the Guillain-Barré syndrome after using anti-COVID-19 ChAdOx1 nCoV-19 vaccine. <i>Case Presentation</i>. An adult, 29-year-old male, without relevant medical history, who developed neuromuscular symptoms nine days after administration of the first dose of anti-COVID-19 ChAdOx1 nCoV-19 vaccine.</p><p><strong>Results: </strong>Symptoms appeared nine days after vaccination, with lower limbs paresthesia. Three days later, paresthesia of upper limbs occurred. The following day, distal weakness of limbs, with standing and gripping difficulties, occurred. The clinical evaluation demonstrated dysarthria, incomplete palpebral closure, bilateral facial, and tongue paresis. The electromyography was compatible with a motor demyelinating polyneuropathy, confirming the diagnosis of the Guillain-Barré syndrome. Management with five sessions of plasma exchange was prescribed, with favorable clinical results.</p><p><strong>Conclusions: </strong>Clinical and laboratory tests confirmed the Guillain-Barré syndrome and the time elapsed from the date of the vaccine administration to the appearance of initial symptoms, added to the absence of other causes, and allowed to establish that the disease was caused by the vaccination.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"3290956"},"PeriodicalIF":1.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49688856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}