Thuraya Al-Busaidi, Fatma Al-Bulushi, Adil Al-Zadjali, Abdulaziz Bakathir, Abdullah Balkhair, Ibrahim Al Busaidi
{"title":"Overcoming the Odds: Successful Treatment of Disseminated Mucormycosis with Gastrointestinal and Jaw Involvement in a Patient with Acute Myeloid Leukemia.","authors":"Thuraya Al-Busaidi, Fatma Al-Bulushi, Adil Al-Zadjali, Abdulaziz Bakathir, Abdullah Balkhair, Ibrahim Al Busaidi","doi":"10.1155/2023/5556540","DOIUrl":"10.1155/2023/5556540","url":null,"abstract":"<p><p>Disseminated mucormycosis is a rare life-threatening fungal infection that is uniquely seen in severely immunocompromised patients including those with hematological malignancies. We report a case of disseminated mucormycosis with a biopsy-proven gastrointestinal and oral cavity involvement in a patient with acute myeloid leukemia during induction chemotherapy. The patient had a successful outcome with limited resection of the involvement bowel segment, multiple maxillary dental extractions, debridement of the alveolus and hard palate, and combined antifungal therapy. After clinical improvement, stable infection on serial abdominal imaging, and completion of 6 weeks of combined antifungal therapy, consolidation chemotherapy was given, and molecular remission was achieved. The patient remained clinically well on secondary antifungal prophylaxis.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"5556540"},"PeriodicalIF":1.1,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10564569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41192164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maryam Hasanzarrini, Amir Mohammad Salehi, Samira Nirumandi Jahromi
{"title":"Development of Peptic Ulcer following Second Shot of Sputnik V Vaccine: A Case Report and Literature Review of Rare Side Effects of Sputnik V Vaccine.","authors":"Maryam Hasanzarrini, Amir Mohammad Salehi, Samira Nirumandi Jahromi","doi":"10.1155/2023/9989515","DOIUrl":"https://doi.org/10.1155/2023/9989515","url":null,"abstract":"<p><p>Considering the global spread of the coronavirus disease 2019 (COVID-19), it is expected that vaccination against its causative agent, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), will reduce the related morbidity and mortality. However, the safety of the COVID-19 vaccines and their potential and unknown side effects are a matter of concern. With the ongoing development and implementation of COVID-19 vaccination programs around the world, the side effects, safety, and effectiveness of these vaccines are gradually being reported, providing researchers with valuable information that can affect the production and utilization of the COVID-19 vaccines. The present study intended to report a case of peptic ulcer disease (PUD) development following vaccination with Gam-COVID-Vac, a vector-based COVID-19 vaccine containing two recombinant human adenoviruses (rAd26 and rAd5).</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"9989515"},"PeriodicalIF":1.1,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10539083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41107961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tariq Abdul Hamid, Nayab Mustafa, Almas Zulfiquar Parkar, Sherin Marina Varghese, Ossama Sayedahmed, Mohammed Ghanaim
{"title":"Manifestation of Guillain-Barre Syndrome in a Case of Monkeypox Virus Infection: A Rare Case Report.","authors":"Tariq Abdul Hamid, Nayab Mustafa, Almas Zulfiquar Parkar, Sherin Marina Varghese, Ossama Sayedahmed, Mohammed Ghanaim","doi":"10.1155/2023/2426659","DOIUrl":"https://doi.org/10.1155/2023/2426659","url":null,"abstract":"<p><p>Monkeypox virus (MPXV) is one of the rare zoonotic infections caused by orthopoxvirus. MPXV has recently been an evolving threat to public health with its contagious human-to-human transmission. Various presentations of MPXV infection have been reported ranging from generalised symptoms such as fever, chills, body aches, and swollen lymph nodes to dermatological presentations. Neurological manifestations that have been reported include headaches, myalgia, seizures, and even mood disturbances. Postinfectious complications such as encephalitis, vision problems, and skin infections have also been noticed. Guillain-Barre Syndrome (GBS) is an acquired acute inflammatory polyradiculoneuropathy characterized by progressive, symmetrical, proximal, and distal tingling and weakness. Although various microorganisms are known to cause GBS and have been linked to the smallpox vaccine, they are rarely linked to MPXV disease. In this report, we describe a case of a confirmed monkeypox infection in a patient presenting with Guillain-Barre Syndrome.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"2426659"},"PeriodicalIF":1.1,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41100775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mhd Mustafa Albitar, Nafiza Martini, Sandy Alkhalil, Tamim Alsuliman, Ali Alrstom
{"title":"Malaria and an Amoebic Abscess in a Returning Traveler from Liberia.","authors":"Mhd Mustafa Albitar, Nafiza Martini, Sandy Alkhalil, Tamim Alsuliman, Ali Alrstom","doi":"10.1155/2023/1466397","DOIUrl":"10.1155/2023/1466397","url":null,"abstract":"<p><p>Malaria is an infectious <i>Anopheles</i> mosquito-borne disease caused by five different eukaryotic protozoa parasites. Amoebiasis is a parasitic infection caused by <i>Entamoeba histolytica</i>. Both diseases are widespread in Liberia. A returning traveler was diagnosed and treated for malaria, and 20 days later, an amoebic liver abscess was discovered, meaning that the malaria infection masked the amoebic infection, which emphasizes the importance of a complete examination of returning travelers, especially for those returning from Sub-Saharan Africa, where coinfections are more common. Herein, we propose that the relationship between Malaria and amoebic liver abscesses should be explored by researching the effects of malaria on ferritin levels and the immune components in the liver and whether it helps the emergence of hepatic amoebic abscesses or not.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"1466397"},"PeriodicalIF":1.1,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9901467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Disseminated Tuberculosis Mimicking as Crohn's Disease in a Paediatric Patient.","authors":"Elizabeth Feenstra, Yentl Driesen, Nicolette Moes, Nathalie Jouret, Koen Vanden Driessche","doi":"10.1155/2023/7312630","DOIUrl":"10.1155/2023/7312630","url":null,"abstract":"<p><p>Tuberculosis is an important infectious disease for children worldwide. The clinical presentation of tuberculosis in children is diverse and, depending on the affected organs, it is often accompanied with nonspecific symptoms that can mimic other diseases. In this report, we present a case of disseminated tuberculosis in an 11-year-old boy with intestinal followed by pulmonary involvement. The diagnosis was delayed for several weeks due to the clinical picture which was mimicking Crohn's disease, the known difficulties in diagnostic tests and the improvement on meropenem. This case demonstrates the importance of a detailed microscopic examination of gastrointestinal biopsies and the tuberculostatic effect of meropenem which physicians should be aware of.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"7312630"},"PeriodicalIF":1.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9810950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coinfection with SARS-CoV-2 and Cytomegalovirus in a Patient with Mild COVID-19.","authors":"Kazuya Ura, Yumi Goubaru, Misato Motoya, Hidehiro Ishii","doi":"10.1155/2023/6684783","DOIUrl":"10.1155/2023/6684783","url":null,"abstract":"<p><p>Persistent fever due to coronavirus disease 2019 (COVID-19) is a considerable issue for patients and physicians that requires a broad differential diagnosis and evaluation of complications. Coinfections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and various respiratory viruses have also been reported. In severe cases of COVID-19, cytomegalovirus (CMV) reactivation or CMV coinfection with SARS-CoV-2 has been reported in association with critical illnesses and immunosuppressive therapy; however, in mild COVID-19 cases, CMV coinfection with SARS-CoV-2 has been reported only in severely immunocompromised patients, and its incidence and clinical importance remain unclear. Herein, we report a rare case of coinfection with SARS-CoV-2 and CMV in a patient with mild COVID-19 and untreated diabetes mellitus, which led to persistent fever for approximately 4 weeks. CMV coinfection should be considered in patients with COVID-19 who exhibit persistent fever.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"6684783"},"PeriodicalIF":1.0,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9600578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Severe Malaria with a Rare Tetrad of Blackwater Fever, Acute Renal Failure, Disseminated Intravascular Coagulopathy, and Acute Acalculous Cholecystitis.","authors":"Hira Hanif, Biraj Shrestha, Salina Munankami, Manish Shrestha, Bidhya Poudel, Roopika Reddy, Syed Jaleel, Debra Powell","doi":"10.1155/2023/5796881","DOIUrl":"10.1155/2023/5796881","url":null,"abstract":"<p><strong>Background: </strong>Blackwater fever (BWF) is a severe clinical syndrome occurring as a complication of malarial infection characterized by intravascular hemolysis, hemoglobinuria, and acute renal failure in people exposed to <i>Plasmodium falciparum</i> and, to some extent, in people who were exposed to medications like quinine and mefloquine. The exact pathogenesis of classic BWF remains unclear. The mechanism leading to damage to the red blood cells (RBCs) can be immunologic nonimmunologic, leading to massive intravascular hemolysis. <i>Case Presentation</i>. We present a case of classic blackwater fever in a 24-year-old otherwise previously healthy male without any history of antimalarial prophylaxis use, returning from recent travel to Sierra Leone. He was detected to have <i>P. falciparum</i> malaria in the peripheral smear test. He was treated with artemether/lumefantrine combination therapy. Unfortunately, his presentation was complicated by renal failure and was managed with plasmapheresis and renal replacement therapy.</p><p><strong>Conclusion: </strong>Malaria continues to be a parasitic disease that can have devastating effects and continues to be a challenge globally. Although cases of malaria in the United States are rare and cases of severe malaria, mainly attributed to <i>P. falciparum</i>, are even more uncommon. Care should be taken to retain a high level of suspicion to consider the diagnosis, especially in returning travelers from endemic areas.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"5796881"},"PeriodicalIF":1.1,"publicationDate":"2023-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9838436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Waleed Amsaib M Ahmed, Khalid Ahmed Khalil, Asma Azwari, Gamal T A Ebid, Imran Nazir, Mohamed Hassan Aly
{"title":"Life-Threatening Severe Thrombocytopenia and Mild Autoimmune Hemolytic Anemia Associated with Brucellosis.","authors":"Waleed Amsaib M Ahmed, Khalid Ahmed Khalil, Asma Azwari, Gamal T A Ebid, Imran Nazir, Mohamed Hassan Aly","doi":"10.1155/2023/6608279","DOIUrl":"10.1155/2023/6608279","url":null,"abstract":"<p><strong>Methods: </strong>We report the case of a 73-year-old Saudi female who presented with severe thrombocytopenia and mild autoimmune hemolytic anemia associated with brucellosis. The coexistence of published cases of two hematological disorders with brucellosis is rare.</p><p><strong>Results: </strong>Despite the initial treatment with eltrombopag and intravenous immunoglobulin (IVIG), our patient's platelets count remained low and significantly improved after initiation of brucellosis treatment in the form of rifampicin and doxycycline. <i>Discussion</i>. We conclude by reviewing the case that in many parts of Saudi Arabia, brucellosis remains a prevalent infection. Hence, it should be considered as a possible diagnosis in febrile individuals with no localizing indications and the presence of severe thrombocytopenia in acute febrile illness. Although it is a rare association, it could be related to brucellosis.</p><p><strong>Conclusion: </strong>This is our region's first published case of severe thrombocytopenia and mild autoimmune hemolytic anemia associated with brucellosis. It contributes to the literature on the successful use of rifampicin and doxycycline to treat hematological disorders associated with brucellosis.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"6608279"},"PeriodicalIF":1.0,"publicationDate":"2023-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9191850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helina Fikre, Ermias Teklehaimanot, Rezika Mohammed, Miklol Mengistu, Bewketu Abebe, Johan van Griensven, Saskia van Henten
{"title":"Atypical Mucocutaneous Leishmaniasis Presentation Mimicking Rectal Cancer.","authors":"Helina Fikre, Ermias Teklehaimanot, Rezika Mohammed, Miklol Mengistu, Bewketu Abebe, Johan van Griensven, Saskia van Henten","doi":"10.1155/2023/2768626","DOIUrl":"https://doi.org/10.1155/2023/2768626","url":null,"abstract":"<p><p>Cutaneous leishmaniasis is a neglected tropical disease affecting mostly the exposed skin, causing severe and disfiguring lesions in Ethiopia. In this report, we present two cases of atypical mucocutaneous leishmaniasis; one HIV positive and one HIV negative patient. <i>Cases</i>. A 32-year-old male HIV patient presented with 40 days of bleeding per-rectum and a perianal lesion of 5 years. An erythematous nontender plaque measuring 5 cm by 5 cm was observed over the right perianal area with circumferential constricting firm swelling of the rectum. The patient was cured with AmBisome and miltefosine after an incisional biopsy revealed leishmaniasis. A 40-year-old presented with bleeding per-rectum and stool incontinence of 3 months, generalized body swelling of 2 months, and mass around his anus for ten years. A 6 by 3 cm indurated ulcerating mass surrounding the anus and a fungating circumferential mass of 8 cm were seen above the proximal anal verge. An excisional biopsy revealed leishmaniasis, and the patient was treated with AmBisome but passed away due to complications with colostomy diarrhea. <i>Conclusion</i>. Clinicians should consider atypical mucocutaneous leishmaniasis as a possible diagnosis in patients with chronic skin lesions resembling hemorrhoids and colorectal masses, especially in endemic areas such as Ethiopia, regardless of their HIV status.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"2768626"},"PeriodicalIF":1.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9383846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Immunocompetent Adult Male Presented with a Liver Abscess Caused by the <i>Mycobacterium tuberculosis</i>: A Case Report from India.","authors":"Akash Pawar, Sagar Khadanga, Abhishek Singhai","doi":"10.1155/2023/9049315","DOIUrl":"https://doi.org/10.1155/2023/9049315","url":null,"abstract":"<p><p>A liver abscess is a collection of purulent fluid in the liver parenchyma caused by a variety of etiological organisms such as bacteria, protozoa, and in rare occasions fungi. <i>Mycobacterium tuberculosis</i> (MTB) is a frequent and widespread infection in underdeveloped nations such as India, which can manifest in many ways. Tuberculosis mostly affects the lungs, although it can also affect any organ in the body. We are reporting a case of liver abscess caused by MTB infection in order to raise general awareness among physicians about the importance of suspecting and ruling out tuberculosis as a cause of liver abscess. To the best of our knowledge, there have been very few such cases reported from India/the rest of the world.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2023 ","pages":"9049315"},"PeriodicalIF":1.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10058058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}