Haneyeh Shahbazian, Johannes L Du Pisane, David Brandon, James R Galt, S Cheenu Kappadath, David M Schuster, Minzhi Xing, Ali Afrasiabi, Sandra Gad, Nima Kokabi
{"title":"Quantitative Comparison of Yettirium-90 (Y90) PET/CT and Y90 SPECT/CT Voxel-Based Dosimetry post Resin Y90 Microsphere Radioembolization.","authors":"Haneyeh Shahbazian, Johannes L Du Pisane, David Brandon, James R Galt, S Cheenu Kappadath, David M Schuster, Minzhi Xing, Ali Afrasiabi, Sandra Gad, Nima Kokabi","doi":"10.1007/s00270-026-04620-2","DOIUrl":"https://doi.org/10.1007/s00270-026-04620-2","url":null,"abstract":"<p><strong>Purpose: </strong>To quantitatively compare Y90 PET/CT and Y90 SPECT/CT voxel-based dosimetry after RESIN Y90 TARE in hepatocellular carcinoma (HCC). This was a secondary aim of a previously published prospective single-center trial evaluating low-dose scout RESIN Y90 for treatment planning (NCT04172714).</p><p><strong>Materials and methods: </strong>Thirty patients with 33 treatment-naïve HCC lesions underwent Y90 PET/CT and SPECT/CT after scout and therapeutic RESIN Y90. Voxel-based dosimetry (local deposition method) yielded mean, minimum, and the mean dose to the highest-dosed 30% (V30) and 70% (V70) of the volume, for tumor dose (TD) and non-tumoral liver dose (NTLD). Identical PET/CT-derived contours were applied to the SPECT/CT, and agreement was assessed by Bland-Altman analysis and intraclass correlation (ICC).</p><p><strong>Results: </strong>TD-mean (494 vs. 366 Gy), TD-V30 (594 vs. 408 Gy), and TD-V70 (405 vs. 326 Gy) were higher on PET/CT than SPECT/CT, while NTLD-mean (103 vs. 182 Gy) and NTLD-V70 (77 vs. 141 Gy) were lower on PET/CT (all p < 0.001). Correlations were very strong for TD-mean, TD-min, TD-V30, TD-V70, NTLD-mean, and NTLD-V30 (r > 0.9). Relative to PET/CT, SPECT/CT underestimated TD-mean by 127 Gy (95% limits of agreement -435 to 181 Gy) and overestimated NTLD-mean by 79 Gy; ICC was low for several non-tumoral endpoints (NTLD-mean 0.57, 95% CI -0.09 to 0.86) despite strong correlation.</p><p><strong>Conclusions: </strong>After RESIN Y90 TARE for HCC, PET/CT calculated higher TD and lower NTLD than SPECT/CT, correlating strongly but with a potentially clinically relevant systematic bias and wide limits of agreement. The modalities should not be considered interchangeable without modality-specific thresholds or further validation.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149036431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pietro Zappala, M L J Smits, P W K Vos, P Goossen-Nachtigall, D A F van den Heuvel, P C Jacobs, K P van Lienden, M van Leersum, M van Strijen
{"title":"Feasibility and Usability of Head-Mounted Display Augmented Reality During Routine Radiological Interventions: The Prospective AZURION-AR Study.","authors":"Pietro Zappala, M L J Smits, P W K Vos, P Goossen-Nachtigall, D A F van den Heuvel, P C Jacobs, K P van Lienden, M van Leersum, M van Strijen","doi":"10.1007/s00270-026-04615-z","DOIUrl":"https://doi.org/10.1007/s00270-026-04615-z","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the feasibility, usability, and perceived workload of the AZURION-AR augmented reality (AR) medical device during routine interventional radiology procedures in a real-world clinical setting.</p><p><strong>Materials and methods: </strong>This prospective, single-center, single-arm feasibility study included six interventional radiologists performing 34 AR-assisted vascular and non-vascular procedures. The AZURION-AR system projected virtual monitor and touchscreen interfaces within the operator's visual field. Post-procedural structured interviews and standardized 5-point Likert questionnaires assessed usability (System Usability Scale, SUS; 1-5 per item, max score: 100), workload (NASA Task Load Index, NASA-TLX; 0-21 per domain), and image quality (1-5 scale).</p><p><strong>Results: </strong>Continuous head-mounted display use throughout the procedure occurred in 20 cases (58%); mean wearing time was 40 min [5-140 min] versus a mean procedure duration of 59 min [20-240 min]. Mean SUS score was 64.5 ± 11.1, indicating moderate usability with considerable inter-operator variability. Mean NASA-TLX score was 7.6 ± 1.4, reflecting acceptable workload. Mean image quality score was 3.5 ± 0.6, with substantial variability across interventions. Scores tended to be lower in vascular and complex drainage procedures, reflecting increased effort and frustration, reduced anatomical detail, limited spatial resolution, and technical issues such as battery depletion and signal lag.</p><p><strong>Conclusion: </strong>The AZURION-AR medical device proved feasible for use during routine interventional radiology offering unanimously rated perceived ergonomic advantages. Although usability was moderate, limitations in image resolution, technical reliability, and battery life require further refinement before reliable routine clinical implementation can be achieved, particularly for procedures requiring high spatial resolution and detailed anatomical assessment.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149029800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vinicius Adami Vayego Fornazari, Thiago Franch Nunes, Belarmino Gonçalves, Renato Abu Hana, Grit Armstrong Adler, Muneeb Ahmed
{"title":"Toward a Common Language for Percutaneous Palliative Stenting of Malignant Hilar Biliary Obstruction: A Three-Domain Descriptor Framework.","authors":"Vinicius Adami Vayego Fornazari, Thiago Franch Nunes, Belarmino Gonçalves, Renato Abu Hana, Grit Armstrong Adler, Muneeb Ahmed","doi":"10.1007/s00270-026-04618-w","DOIUrl":"https://doi.org/10.1007/s00270-026-04618-w","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149029796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susan van der Lei, Madelon Dijkstra, Elizabeth M Ruiz, Nuran Seneviratne, Danielle J W Vos, Praveen Peddu, Govindarajan Narayanan, Martijn R Meijerink
{"title":"Irreversible Electroporation for Colorectal Liver Metastases: Long-term Outcomes from a Transatlantic Multicenter Study.","authors":"Susan van der Lei, Madelon Dijkstra, Elizabeth M Ruiz, Nuran Seneviratne, Danielle J W Vos, Praveen Peddu, Govindarajan Narayanan, Martijn R Meijerink","doi":"10.1007/s00270-026-04617-x","DOIUrl":"https://doi.org/10.1007/s00270-026-04617-x","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate safety and long-term oncologic outcomes of irreversible electroporation (IRE) for colorectal liver metastases (CRLM) across three high-volume expert centres.</p><p><strong>Materials and methods: </strong>This retrospective multicentre study included patients treated with IRE for unresectable and unablatable CRLM between 2012 and 2025. The primary outcome measure was local tumour progression free-survival (LTPFS). Secondary outcome measures included local control (LC) allowing repeat treatment, overall survival (OS), distant progression-free survival (DPFS), adverse events (AE; CTCAE v5.0) and length-of-hospital-stay.</p><p><strong>Results: </strong>Overall, 162 patients underwent 191 IRE procedures for 219 tumours. Median follow-up was 33.7 months. Per-tumour LTPFS at 1, 2, and 3-years was 68.2%, 55.5%, and 52.6%. Tumours ≤ 3cm demonstrated superior LTPFS compared with tumours >3cm, with 1, 2 and 3-year LTPFS rates of 77.5%, 63.8%, and 60.3% versus 37.4%, 28.5, and 28.5%, (HR 2.89; 95% CI 1.82-4.60; p<0.001). LTPFS did not differ between centres (p = 0.80). Per-tumour LC rates at 1, 2, and 3-years were 97.4%, 95.7%, and 94.8%. OS at 1, 3, 5 and 10-years was 89.3%, 44.6%, 24.2%, and 14.0%. AEs occurred in 23.0% of procedures, predominantly grade 1-2 (72.7%); no grade 5 events occurred. Median hospital-stay was 1 day (IQR 1-2).</p><p><strong>Conclusion: </strong>IRE is a feasible and safe treatment option in expert centres for selected patients with CRLM, ineligible for thermal ablation or resection. Tumour size is a key determinant of LTP, with superior outcomes in lesions ≤ 3cm. Local recurrences are frequently amenable to repeat local treatment, eventually resulting in durable LC in the majority of patients.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149029831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Avinash Deshwal, Padraig Cronin, Hugo C Temperley, Niall J O'Sullivan, Wanyang Qian, Abhinav Deshwal, Rostyslav Nikolenko, James Ryan, Mohamed Elfaki, Nicholas Clausen, Reuben D Mac Curtain, Matthew Mullins, Stephen P Power, Benjamin M Mac Curtain, Ardeshir R Rastinehad
{"title":"Transrenal Ureteric Embolic Occlusion for Refractory Urinary Leakage and Fistulae: A Systematic Review and Meta-analysis.","authors":"Avinash Deshwal, Padraig Cronin, Hugo C Temperley, Niall J O'Sullivan, Wanyang Qian, Abhinav Deshwal, Rostyslav Nikolenko, James Ryan, Mohamed Elfaki, Nicholas Clausen, Reuben D Mac Curtain, Matthew Mullins, Stephen P Power, Benjamin M Mac Curtain, Ardeshir R Rastinehad","doi":"10.1007/s00270-026-04621-1","DOIUrl":"https://doi.org/10.1007/s00270-026-04621-1","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the technical success, clinical success, safety, and re-intervention rates of ureteric embolic occlusion in patients with refractory urinary leakage or fistulae who were unsuitable for surgical management, and to summarise the available evidence regarding procedural durability and adverse events.</p><p><strong>Materials and methods: </strong>PubMed, EMBASE, and Cochrane CENTRAL were searched through 31 May 2026 for studies reporting outcomes of permanent ureteric embolic occlusion. Eligible studies underwent independent screening, data extraction, quality assessment, and meta-analysis. Pooled technical success, clinical success, and re-intervention rates were calculated using a random effects model with 95% confidence intervals.</p><p><strong>Results: </strong>Twelve retrospective studies involving 129 patients and 209 ureters were included. Pooled technical success was 100% (95% CI, 0.99-1.00), demonstrating near-universal immediate ureteric occlusion. Clinical success was 96% (95% CI, 0.87-1.00), although definitions of clinical response varied between studies. The overall re-intervention rate was 7.2% (95% CI, 0-0.09), reflecting repeat embolisation for recanalisation or persistent urinary leakage. No procedure-related mortality or major complications were reported. Adverse events were generally minor and included device migration, nephrostomy-related complications, urinary tract infections, and rare vascular complications.</p><p><strong>Conclusion: </strong>Ureteric embolic occlusion provides excellent short-term technical and clinical outcomes with minimal morbidity and low re-intervention rates in carefully selected non-surgical patients. However, the available evidence is limited by small retrospective cohorts, heterogeneous outcome definitions, and limited long-term follow-up. Future prospective multicentre studies should standardise definitions of clinical success, assess long-term durability, report nephrostomy-associated morbidity and patient-reported outcomes, and directly compare different embolic techniques and materials used more comprehensively.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149029832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Re-intervention After Balloon Pulmonary Angioplasty: A Staging Decision, Not a Failure.","authors":"Nariman Nezami, Peiman Habibollahi","doi":"10.1007/s00270-026-04623-z","DOIUrl":"https://doi.org/10.1007/s00270-026-04623-z","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149029852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Giurazza, Anna Maria Ierardi, José Urbano, Clare Bent, Pietro Roccatagliata, Romaric Loffroy
{"title":"CIRSE Standards of Practice for the Use of Non-sclerosant Liquid Embolic Agents in IR Practice.","authors":"Francesco Giurazza, Anna Maria Ierardi, José Urbano, Clare Bent, Pietro Roccatagliata, Romaric Loffroy","doi":"10.1007/s00270-026-04610-4","DOIUrl":"https://doi.org/10.1007/s00270-026-04610-4","url":null,"abstract":"<p><strong>Background: </strong>Non-sclerosant liquid embolic agents are safe and effective embolics that have been used in interventional radiology for more than 50 years, in both emergency and elective scenarios.</p><p><strong>Purpose: </strong>This document aims to review the chemical principles and technical considerations involved, to make recommendations regarding clinical indications for the use of non-sclerosant liquid embolic agents, and to review the literature regarding outcomes and complications. CIRSE Standards of Practice documents are not intended to impose a standard of clinical patient care, but to recommend a reasonable approach to, and best practices for, procedural performance, in this instance the use of non-sclerosant liquid embolic agents.</p><p><strong>Methods: </strong>The writing group was established by the CIRSE Standards of Practice Committee and consisted of five clinicians with internationally recognised expertise in non-sclerosant liquid embolic agents and a research assistant (P.R.). The writing group reviewed the existing literature on non-sclerosant liquid embolic agents, performing a pragmatic evidence search using PUBMED and EMBASE focussing on English-language publications, preferably from 2009 up to December 2025, and including more than ten patients. Where clear gaps were evident, older literature was searched and select references included. The final recommendations were formulated through consensus.</p><p><strong>Results: </strong>Non-sclerosant liquid embolic agents are represented by cyanoacrylates and polymers which are safe and effective agents that can be used in a wide range of clinical scenarios, resulting in effective embolization even in patients with impaired coagulation function. Knowing their chemical properties provides understanding of their correct preparation, technical application and clinical indication. Compared to mechanical and particulate agents, non-sclerosant liquid embolic agents present a steeper learning curve, and thus, thorough training in their use is essential.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149029792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Robotic Bronchoscopic Lung Ablation: Can Evidence Generation Keep Pace with Technological Innovation?","authors":"Nafi Iftekhar, Jim Zhong","doi":"10.1007/s00270-026-04616-y","DOIUrl":"https://doi.org/10.1007/s00270-026-04616-y","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"BOREALIS: Building the Prospective Evidence Base for Curative-Intent Cryoablation of Bone Metastases.","authors":"Ignacio Andrés-Cano","doi":"10.1007/s00270-026-04625-x","DOIUrl":"https://doi.org/10.1007/s00270-026-04625-x","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}