Association Between Geriatric Nutritional Risk Index and Discharge Outcome after Elective Thoracic Endovascular Aortic Repair.

IF 2.8 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Takafumi Ouchi, Noriyuki Kato, Hiroaki Kato, Takatoshi Higashigawa, Hisato Ito, Ken Nakajima, Shuji Chino, Toshiya Tokui, Kensuke Oue, Toru Mizumoto, Yasutaka Ichikawa, Hajime Sakuma
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Abstract

Purpose: To evaluate the utility of the Geriatric Nutritional Risk Index (GNRI) in predicting nonhome discharge (NHD) and delayed discharge after elective thoracic endovascular aortic repair (TEVAR).

Methods: The study population included patients undergoing elective simple TEVAR for intact thoracic aortic aneurysm or subacute or chronic aortic dissection between January 2009 and December 2022 and not experiencing neurological complications or re-interventions during hospitalization. The primary outcome measure was NHD and significantly delayed discharge. GNRI was calculated using the following equation: GNRI = 14.89 × serum albumin (g/dL) + 41.7 × (body mass index [kg/m2] / 22). A univariable logistic regression model was used to determine the odds ratio for GNRI. The predictive performance of GNRI was evaluated using the area under the receiver operating characteristic curve (AUC).

Results: A total of 229 patients were analyzed and the overall rate of the primary outcome was 5.7% (NHD, n = 6; delayed discharge, n = 10; both, n = 3). Patients with the primary outcome were more likely to have a lower GNRI (98 vs 103; P = .01) than those without. The logistic regression model showed that a high GNRI was protective against NHD (odds ratio, 0.38; 95% confidence interval, 0.18-0.76; P = .008). The AUC for GNRI was 0.710 (95% confidence interval, 0.602-0.821). The sensitivity, specificity, positive predictive value, and negative predictive value of GNRI < 92 were 23%, 89%, 11%, and 95%, respectively.

Conclusions: Preoperative evaluation of GNRI may be useful in predicting NHD and delayed discharge.

择期胸腔血管内主动脉修复术后老年人营养风险指数与出院预后的关系。
目的:评价老年人营养风险指数(GNRI)在预测择期胸腔血管内主动脉修复(TEVAR)术后非居家出院(NHD)和延迟出院中的应用价值。方法:研究人群包括2009年1月至2022年12月期间接受选择性简单TEVAR治疗完整胸主动脉瘤或亚急性或慢性主动脉夹层的患者,且住院期间未发生神经系统并发症或再次干预。主要结局指标为NHD和显著延迟出院。GNRI的计算公式为:GNRI = 14.89 ×血清白蛋白(g/dL) + 41.7 ×(体重指数[kg/m2] / 22)。采用单变量logistic回归模型确定GNRI的优势比。采用受者工作特征曲线下面积(AUC)评价GNRI的预测性能。结果:共分析229例患者,主要转归率为5.7% (NHD, n = 6;延迟放电,n = 10;都是,n = 3)。具有主要结局的患者更有可能具有较低的GNRI (98 vs 103;P = 0.01)。logistic回归模型显示,高GNRI对NHD有保护作用(优势比,0.38;95%置信区间为0.18-0.76;p = .008)。GNRI的AUC为0.710(95%可信区间为0.602-0.821)。结论:术前评估GNRI对NHD和延迟出院有一定的预测价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.50
自引率
13.80%
发文量
306
审稿时长
3-8 weeks
期刊介绍: CardioVascular and Interventional Radiology (CVIR) is the official journal of the Cardiovascular and Interventional Radiological Society of Europe, and is also the official organ of a number of additional distinguished national and international interventional radiological societies. CVIR publishes double blinded peer-reviewed original research work including clinical and laboratory investigations, technical notes, case reports, works in progress, and letters to the editor, as well as review articles, pictorial essays, editorials, and special invited submissions in the field of vascular and interventional radiology. Beside the communication of the latest research results in this field, it is also the aim of CVIR to support continuous medical education. Articles that are accepted for publication are done so with the understanding that they, or their substantive contents, have not been and will not be submitted to any other publication.
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